Custirsen (OGX-011) combined with cabazitaxel and prednisone versus cabazitaxel and prednisone alone in patients with metastatic castration-resistant prostate cancer previously treated with docetaxel (AFFINITY): a randomised, open-label, internation

scientific article published on 9 October 2017

Custirsen (OGX-011) combined with cabazitaxel and prednisone versus cabazitaxel and prednisone alone in patients with metastatic castration-resistant prostate cancer previously treated with docetaxel (AFFINITY): a randomised, open-label, internation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S1470-2045(17)30605-8
P698PubMed publication ID29033099

P50authorKarim FizaziQ73569107
Fred SaadQ88065306
Tomasz M BeerQ90949746
P2093author name stringFlorence Joly
Vsevolod Matveev
Kim N Chi
Sebastien J Hotte
Aude Fléchon
Gwenaelle Gravis
Brent Blumenstein
Boris Alekseev
Cindy A Jacobs
Patricia S Stewart
Zafar Malik
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Clusterin knockdown using the antisense oligonucleotide OGX-011 re-sensitizes docetaxel-refractory prostate cancer PC-3 cells to chemotherapyQ40003248
Reduction in serum clusterin is a potential therapeutic biomarker in patients with castration-resistant prostate cancer treated with custirsen.Q42685237
Randomized phase II study of docetaxel and prednisone with or without OGX-011 in patients with metastatic castration-resistant prostate cancer.Q42928474
The interval from the last cycle of docetaxel-based chemotherapy to progression is associated with the efficacy of subsequent docetaxel in patients with prostate cancerQ43059748
Abiraterone acetate plus prednisone versus placebo plus prednisone in chemotherapy-naive men with metastatic castration-resistant prostate cancer (COU-AA-302): final overall survival analysis of a randomised, double-blind, placebo-controlled phase 3Q45957143
Docetaxel-based chemotherapy in elderly patients (age 75 and older) with castration-resistant prostate cancerQ46427019
A phase I pharmacokinetic and pharmacodynamic study of OGX-011, a 2'-methoxyethyl antisense oligonucleotide to clusterin, in patients with localized prostate cancerQ46689589
Activity of cabazitaxel in castration-resistant prostate cancer progressing after docetaxel and next-generation endocrine agentsQ47931535
Custirsen in combination with docetaxel and prednisone for patients with metastatic castration-resistant prostate cancer (SYNERGY trial): a phase 3, multicentre, open-label, randomised trial.Q51102220
Clusterin Has Chaperone-like Activity Similar to That of Small Heat Shock ProteinsQ57639622
P433issue11
P921main subjectdocetaxelQ420436
P304page(s)1532-1542
P577publication date2017-10-09
P1433published inLancet Oncology CommissionQ13747613
P1476titleCustirsen (OGX-011) combined with cabazitaxel and prednisone versus cabazitaxel and prednisone alone in patients with metastatic castration-resistant prostate cancer previously treated with docetaxel (AFFINITY): a randomised, open-label, internation
P478volume18

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