Custirsen in combination with docetaxel and prednisone for patients with metastatic castration-resistant prostate cancer (SYNERGY trial): a phase 3, multicentre, open-label, randomised trial.

scientific article published on 7 March 2017

Custirsen in combination with docetaxel and prednisone for patients with metastatic castration-resistant prostate cancer (SYNERGY trial): a phase 3, multicentre, open-label, randomised trial. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S1470-2045(17)30168-7
P8608Fatcat IDrelease_l7ir45nntfhj5g2ednvjekfedq
P698PubMed publication ID28283282

P50authorFred SaadQ88065306
Celestia HiganoQ126877419
P2093author name stringMartin Gleave
Arnulf Stenzl
Johann S de Bono
Axel S Merseburger
Kim N Chi
Jean-Marc Ferrero
Andries M Bergman
Som D Mukherjee
Susan Feyerabend
Pawel Zalewski
Gwenaelle Gravis
Brent Blumenstein
James Reeves
Cindy Jacobs
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Clusterin expression predicts survival of invasive cervical cancer patients treated with radical hysterectomy and systematic lymphadenectomy.Q43661967
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A phase I pharmacokinetic and pharmacodynamic study of OGX-011, a 2'-methoxyethyl antisense oligonucleotide to clusterin, in patients with localized prostate cancerQ46689589
Clusterin Has Chaperone-like Activity Similar to That of Small Heat Shock ProteinsQ57639622
Clusterin expression and univariate analysis of overall survival in human breast cancerQ79377021
Value of clusterin immunoreactivity as a predictive factor in muscle-invasive urothelial bladder carcinomaQ82264106
Randomized, open-label phase III trial of docetaxel plus high-dose calcitriol versus docetaxel plus prednisone for patients with castration-resistant prostate cancerQ83831101
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Clusterin is an ATP-independent chaperone with very broad substrate specificity that stabilizes stressed proteins in a folding-competent stateQ24290651
Clusterin facilitates COMMD1 and I-kappaB degradation to enhance NF-kappaB activity in prostate cancer cellsQ24294824
Clusterin inhibits apoptosis by interacting with activated BaxQ24316499
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Docetaxel and atrasentan versus docetaxel and placebo for men with advanced castration-resistant prostate cancer (SWOG S0421): a randomised phase 3 trialQ28294857
The mutational landscape of lethal castration-resistant prostate cancerQ29614634
Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancerQ29616218
Increased survival with enzalutamide in prostate cancer after chemotherapyQ29617511
Abiraterone and increased survival in metastatic prostate cancerQ29617512
Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomised open-label trialQ29620155
Clusterin facilitates stress-induced lipidation of LC3 and autophagosome biogenesis to enhance cancer cell survivalQ30611108
Design and end points of clinical trials for patients with progressive prostate cancer and castrate levels of testosterone: recommendations of the Prostate Cancer Clinical Trials Working GroupQ33566395
Enzalutamide in metastatic prostate cancer before chemotherapyQ34422206
Chemosensitization of human renal cell cancer using antisense oligonucleotides targeting the antiapoptotic gene clusterinQ34780639
Docetaxel and prednisone with or without lenalidomide in chemotherapy-naive patients with metastatic castration-resistant prostate cancer (MAINSAIL): a randomised, double-blind, placebo-controlled phase 3 trialQ35572535
P433issue4
P921main subjectdocetaxelQ420436
multicenter clinical trialQ6934595
phase III clinical trialQ42824827
P304page(s)473-485
P577publication date2017-03-07
P1433published inLancet Oncology CommissionQ13747613
P1476titleCustirsen in combination with docetaxel and prednisone for patients with metastatic castration-resistant prostate cancer (SYNERGY trial): a phase 3, multicentre, open-label, randomised trial.
P478volume18

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