Plasminogen activator inhibitor-1 regulates the vascular expression of vitronectin

scientific article

Plasminogen activator inhibitor-1 regulates the vascular expression of vitronectin is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/JTH.13869
P932PMC publication ID5716874
P698PubMed publication ID29028290

P2093author name stringJ Wu
Y Luo
Y Ji
M Luo
R Li
W P Fay
P2860cites workPharmacological Targeting of Plasminogen Activator Inhibitor-1 Decreases Vascular Smooth Muscle Cell Migration and Neointima FormationQ42738253
Plasminogen activator inhibitor type 1 promotes the self-association of vitronectin into complexes exhibiting altered incorporation into the extracellular matrixQ43858114
Vitronectin is up-regulated after vascular injury and vitronectin blockade prevents neointima formationQ43939747
Purification of a protein from bovine plasma that binds to type 1 plasminogen activator inhibitor and prevents its interaction with extracellular matrix. Evidence that the protein is vitronectinQ44850338
Binding of type 1 plasminogen activator inhibitor to the extracellular matrix of cultured bovine endothelial cells.Q45944655
Kinetic analysis of integrin-dependent cell adhesion on vitronectin--the inhibitory potential of plasminogen activator inhibitor-1 and RGD peptidesQ47881843
Significance of vitronectin and PAI-1 activity levels in carotid artery disease: comparison of symptomatic and asymptomatic patients.Q50864888
Vitronectin inhibits plasminogen activator inhibitor-1-induced signalling and chemotaxis by blocking plasminogen activator inhibitor-1 binding to the low-density lipoprotein receptor-related protein.Q53460186
Augmented arterial wall expression of type-1 plasminogen activator inhibitor induced by thrombosisQ57222793
Immunoelectron-microscopic localization of S-protein/vitronectin in human atherosclerotic wallQ69102361
Induction of vascular smooth muscle cell expression of plasminogen activator inhibitor-1 by thrombinQ70523860
Increased intramural expression of plasminogen activator inhibitor type 1 after balloon injury: a potential progenitor of restenosisQ72811871
Inhibition of angiogenesis in vivo by plasminogen activator inhibitor-1Q73203966
Vitronectin expression and interaction with receptors in smooth muscle cells from human atheromatous plaqueQ74251022
Plasminogen activator inhibitor-1 contains a cryptic high affinity binding site for the low density lipoprotein receptor-related proteinQ74299355
Recognition of alpha 2-macroglobulin by the low density lipoprotein receptor-related protein requires the cooperation of two ligand binding cluster regionsQ74379625
Binding of receptor-recognized forms of alpha2-macroglobulin to the alpha2-macroglobulin signaling receptor activates phosphatidylinositol 3-kinaseQ74567337
C-reactive protein enhances tissue factor expression by vascular smooth muscle cells: mechanisms and in vivo significanceQ80706514
The serpin PAI-1 inhibits cell migration by blocking integrin alpha V beta 3 binding to vitronectinQ24310652
Endocytic receptor LRP together with tPA and PAI-1 coordinates Mac-1-dependent macrophage migrationQ24546040
Direct binding of occupied urokinase receptor (uPAR) to LDL receptor-related protein is required for endocytosis of uPAR and regulation of cell surface urokinase activityQ24633333
Regulation of proteolytic enzymes and inhibitors in two smooth muscle cell phenotypesQ28570169
Sequence identity between the alpha 2-macroglobulin receptor and low density lipoprotein receptor-related protein suggests that this molecule is a multifunctional receptorQ28610930
Interaction of vitronectin with collagenQ28645683
Plasminogen activator inhibitor type 1 is increased in the arterial wall of type II diabetic subjectsQ30700072
Vitronectin is not essential for normal mammalian development and fertility.Q33679049
Plasminogen activator inhibitor-1 gene-deficient mice. I. Generation by homologous recombination and characterizationQ33909797
Tiplaxtinin, a novel, orally efficacious inhibitor of plasminogen activator inhibitor-1: design, synthesis, and preclinical characterizationQ33979344
Three decades of research on plasminogen activator inhibitor-1: a multifaceted serpinQ34333539
Vitronectin in vascular context: facets of a multitalented matricellular proteinQ34631318
Vitronectin (serum spreading factor): its localisation in normal and fibrotic tissueQ34660527
Vitronectin gene expression in vivo. Evidence for extrahepatic synthesis and acute phase regulationQ34719534
Localization of vitronectin in the normal and atherosclerotic human vessel wallQ34740237
Old dogs and new tricks: proteases, inhibitors, and cell migrationQ35167706
The vitronectin-binding function of PAI-1 exacerbates lung fibrosis in miceQ35182731
Mouse model of venous bypass graft arteriosclerosisQ35753478
The human alpha 2-macroglobulin receptor: identification of a 420-kD cell surface glycoprotein specific for the activated conformation of alpha 2-macroglobulinQ36223019
Is plasminogen activator inhibitor-1 the molecular switch that governs urokinase receptor-mediated cell adhesion and release?Q36237406
Plasminogen activator inhibitor-1 detaches cells from extracellular matrices by inactivating integrinsQ36324236
Vitronectin in atherosclerotic diseaseQ36388057
Molecular evolution of plasminogen activator inhibitor-1 functional stabilityQ36688372
PAI-1 antagonists: predictable indications and unconventional applicationsQ36952097
Increased type 1 plasminogen activator inhibitor gene expression in atherosclerotic human arteriesQ37131350
Bleomycin-induced pulmonary fibrosis in transgenic mice that either lack or overexpress the murine plasminogen activator inhibitor-1 geneQ37351382
Plasminogen activator inhibitor-1 inhibitors: a patent review (2006-present).Q38092174
The low density lipoprotein receptor-related protein is a motogenic receptor for plasminogen activator inhibitor-1.Q40582221
IL-6 stimulates vitronectin gene expression in vivoQ41666791
Multifaceted role of plasminogen activator inhibitor-1 in regulating early remodeling of vein bypass graftsQ42128982
Inhibition of HCV by the serpin antithrombin IIIQ42406960
Plasminogen activator inhibitor-1 and vitronectin expression level and stoichiometry regulate vascular smooth muscle cell migration through physiological collagen matricesQ42425209
P433issue12
P304page(s)2451-2460
P577publication date2017-10-13
P1433published inJournal of Thrombosis and HaemostasisQ6296004
P1476titlePlasminogen activator inhibitor-1 regulates the vascular expression of vitronectin
P478volume15

Reverse relations

cites work (P2860)
Q90574765ACT001, a novel PAI-1 inhibitor, exerts synergistic effects in combination with cisplatin by inhibiting PI3K/AKT pathway in glioma
Q55491477Association between plasminogen activator inhibitor-1 and cardiovascular events: a systematic review and meta-analysis.
Q93093507Evaluation of Serum Levels of Inflammation, Fibrinolysis and Oxidative Stress Markers in Coronary Artery Disease Prediction: A Cross-Sectional Study

Search more.