Misidentification of transthyretin and immunoglobulin variants by proteomics due to methyl lysine formation in formalin-fixed paraffin-embedded amyloid tissue

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Misidentification of transthyretin and immunoglobulin variants by proteomics due to methyl lysine formation in formalin-fixed paraffin-embedded amyloid tissue is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1080/13506129.2017.1385452
P698PubMed publication ID29016222

P50authorSara MottaQ57022158
V BellottiQ72990986
Pietroluigi MauriQ73050672
Guglielmo VeronaQ86281638
Graham W TaylorQ89523480
Sofia GiorgettiQ92289341
Dorota RowczenioQ92345353
Janet A GilbertsonQ114292763
P2093author name stringJulian D Gillmore
Antonella De Palma
Diana Canetti
Lucia Di Vagno
Nigel Brian Rendell
Palma Patrizia Mangione
Phillip N Hawkins
Tamar Rezk
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Fibril in senile systemic amyloidosis is derived from normal transthyretinQ24558717
Dissecting the structure, thermodynamic stability, and aggregation properties of the A25T transthyretin (A25T-TTR) variant involved in leptomeningeal amyloidosis: identifying protein partners that co-aggregate during A25T-TTR fibrillogenesis in [...]Q27675618
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Immunoglobulin derived depositions in the nervous system: novel mass spectrometry application for protein characterization in formalin-fixed tissuesQ33361143
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The amyloidogenic V122I transthyretin variant in elderly black AmericansQ35242225
A comparison of immunohistochemistry and mass spectrometry for determining the amyloid fibril protein from formalin-fixed biopsy tissueQ35552353
Unrestricted modification search reveals lysine methylation as major modification induced by tissue formalin fixation and paraffin embedding.Q35590688
A novel mechano-enzymatic cleavage mechanism underlies transthyretin amyloidogenesisQ36159473
Implementation and evaluation of amyloidosis subtyping by laser-capture microdissection and tandem mass spectrometryQ36178028
Marked biochemical difference in amyloid proportion between intra- and extraocular tissues in a liver-transplanted patient with hereditary ATTR amyloidosisQ36248042
An analysis of the sequences of the variable regions of Bence Jones proteins and myeloma light chains and their implications for antibody complementarityQ36270017
Assessment of renal response with urinary exosomes in patients with AL amyloidosis: A proof of conceptQ36308575
Mass spectrometric analysis of formalin-fixed paraffin-embedded tissue: unlocking the proteome withinQ36519169
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On typing amyloidosis using immunohistochemistry. Detailled illustrations, review and a note on mass spectrometryQ38028148
Clinical proteomics for diagnosis and typing of systemic amyloidoses.Q38062901
Transthyretin V122I (pV142I)* cardiac amyloidosis: an age-dependent autosomal dominant cardiomyopathy too common to be overlooked as a cause of significant heart disease in elderly African Americans.Q39095033
Genetic testing improves identification of transthyretin amyloid (ATTR) subtype in cardiac amyloidosisQ39298962
Proteomic detection of immunoglobulin light chain variable region peptides from amyloidosis patient biopsiesQ41312103
A practical approach to the diagnosis of systemic amyloidoses.Q41505050
Increasing the accuracy of proteomic typing by decellularisation of amyloid tissue biopsies.Q41519716
False EX1 signatures caused by sample carryover during HX MS analysesQ42744840
Two types of amyloid in a single heartQ42986387
A novel approach for the purification and proteomic analysis of pathogenic immunoglobulin free light chains from serum.Q43586549
Identification of formaldehyde-induced modifications in proteins: reactions with model peptidesQ44669066
Clinical proteome informatics workbench detects pathogenic mutations in hereditary amyloidosesQ45258509
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Amyloid fibril proteins and amyloidosis: chemical identification and clinical classification International Society of Amyloidosis 2016 Nomenclature GuidelinesQ46502103
P433issue4
P304page(s)233-241
P577publication date2017-10-10
P1433published inAmyloidQ4749545
P1476titleMisidentification of transthyretin and immunoglobulin variants by proteomics due to methyl lysine formation in formalin-fixed paraffin-embedded amyloid tissue
P478volume24

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cites work (P2860)
Q91976646Proteomic Analysis for the Diagnosis of Fibrinogen Aα-chain Amyloidosis
Q64360352The complementary role of histology and proteomics for diagnosis and typing of systemic amyloidosis

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