Conditional deletion of ELL2 induces murine prostate intraepithelial neoplasia

scientific article published in November 2017

Conditional deletion of ELL2 induces murine prostate intraepithelial neoplasia is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1530/JOE-17-0112
P932PMC publication ID5679084
P698PubMed publication ID28870994

P50authorKhalid Z. MasoodiQ48235634
Leandro M ColliQ56427644
Laura E PascalQ57144929
Zhou WangQ92438654
Jian ZhangQ95001421
Ricardo Zorzetto Nicoliello VêncioQ102311386
Yujuan WangQ123574061
P2093author name stringYi Lu
Yao Wang
Lora H Rigatti
Tiejun Yang
Yachen Zang
Uma Chandran
June Liu
Xiaonan Qiu
Qiong Song
P2860cites workIdentification, cloning, expression, and biochemical characterization of the testis-specific RNA polymerase II elongation factor ELL3Q22254564
The little elongation complex regulates small nuclear RNA transcriptionQ24300557
Cloning of ELL, a gene that fuses to MLL in a t(11;19)(q23;p13.1) in acute myeloid leukemiaQ24310726
Human mediator subunit MED26 functions as a docking site for transcription elongation factorsQ24310867
EAF2 suppresses hypoxia-induced factor 1α transcriptional activity by disrupting its interaction with coactivator CBP/p300Q24319939
ELL-associated factors 1 and 2 are positive regulators of RNA polymerase II elongation factor ELLQ24531614
The program of androgen-responsive genes in neoplastic prostate epitheliumQ24535711
Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancerQ24616117
Retrovirus-mediated gene transfer of MLL-ELL transforms primary myeloid progenitors and causes acute myeloid leukemias in miceQ24647139
DAVID: Database for Annotation, Visualization, and Integrated DiscoveryQ27499374
ELL2, a new member of an ELL family of RNA polymerase II elongation factorsQ28117345
Analyzing real-time PCR data by the comparative C(T) methodQ28131831
ELL-associated factor 2 (EAF2), a functional homolog of EAF1 with alternative ELL binding propertiesQ28215725
HDAC6 regulates androgen receptor hypersensitivity and nuclear localization via modulating Hsp90 acetylation in castration-resistant prostate cancerQ37484581
Divergent clonal evolution of castration-resistant neuroendocrine prostate cancerQ38768101
The Hsp90 inhibitor, 17-AAG, prevents the ligand-independent nuclear localization of androgen receptor in refractory prostate cancer cellsQ40183503
RTN4-C gene expression in hepatocellular carcinoma and its influence on SMMC7721 cell growth and apoptosis.Q40366476
Identification and characterization of a bovine neurite growth inhibitor (bNI-220).Q42828131
PDS5A, a novel translocation partner of MLL in acute myeloid leukemiaQ44271844
The bHLH transcription factors OLIG2 and OLIG1 couple neuronal and glial subtype specification.Q46021705
Gene expression profile of mouse prostate tumors reveals dysregulations in major biological processes and identifies potential murine targets for preclinical development of human prostate cancer therapy.Q54522194
Angiogenesis and prostate cancer: identification of a molecular progression switchQ73715181
SCC-112, a novel cell cycle-regulated molecule, exhibits reduced expression in human renal carcinomasQ28250311
The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics dataQ28266682
Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortalQ28288215
Suppression of prostate tumor growth by U19, a novel testosterone-regulated apoptosis inducerQ28587720
U19/Eaf2 knockout causes lung adenocarcinoma, B-cell lymphoma, hepatocellular carcinoma and prostatic intraepithelial neoplasiaQ28590029
Nonredundant roles of the elongation factor MEN in postimplantation developmentQ28594021
The mutational landscape of lethal castration-resistant prostate cancerQ29614634
Androgen regulation of spermidine synthase expression in the rat prostateQ31040745
Generation of a prostate epithelial cell-specific Cre transgenic mouse model for tissue-specific gene ablationQ32079218
The expression of androgen-responsive genes is up-regulated in the epithelia of benign prostatic hyperplasiaQ33493120
U19/Eaf2 binds to and stabilizes von hippel-lindau proteinQ33590977
Tumor suppressor U19/EAF2 regulates thrombospondin-1 expression via p53Q33604141
ELL is an HIF-1alpha partner that regulates and responds to hypoxia response in PC3 cellsQ33802059
AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemiaQ33857407
Cell- and gene-specific regulation of primary target genes by the androgen receptorQ34005736
dELL is an essential RNA polymerase II elongation factor with a general role in developmentQ34076115
Transcription elongation factor ELL2 drives Ig secretory-specific mRNA production and the unfolded protein responseQ34364860
A human protein atlas for normal and cancer tissues based on antibody proteomicsQ34446479
Concomitant loss of EAF2/U19 and Pten synergistically promotes prostate carcinogenesis in the mouse modelQ34740903
Development of a reactive stroma associated with prostatic intraepithelial neoplasia in EAF2 deficient miceQ35048524
Dynamic transcriptional events in embryonic stem cells mediated by the super elongation complex (SEC).Q35128809
EAF2 loss enhances angiogenic effects of Von Hippel-Lindau heterozygosity on the murine liver and prostateQ35161330
The eleven-nineteen lysine-rich leukemia gene (ELL2) influences the histone H3 protein modifications accompanying the shift to secretory immunoglobulin heavy chain mRNA productionQ35310763
Regulation of fertility, survival, and cuticle collagen function by the Caenorhabditis elegans eaf-1 and ell-1 genesQ35372544
Influence of E. coli-induced prostatic inflammation on expression of androgen-responsive genes and transforming growth factor beta 1 cascade genes in ratsQ35468651
Prostate pathology of genetically engineered mice: definitions and classification. The consensus report from the Bar Harbor meeting of the Mouse Models of Human Cancer Consortium Prostate Pathology Committee.Q35693712
Sphingosine-1-phosphate receptor inhibition prevents denervation-induced dendritic atrophyQ35976992
RHOBTB3 promotes proteasomal degradation of HIFα through facilitating hydroxylation and suppresses the Warburg effectQ36026989
Physical and Functional Interactions between ELL2 and RB in the Suppression of Prostate Cancer Cell Proliferation, Migration, and Invasion.Q36272250
Cloning of several species of MLL/MEN chimeric cDNAs in myeloid leukemia with t(11;19)(q23;p13.1) translocationQ36700425
Bleach gel: a simple agarose gel for analyzing RNA qualityQ36975439
Gene Expression Profiling Reveals Regulation of ERK Phosphorylation by Androgen-Induced Tumor Suppressor U19/EAF2 in the Mouse Prostate.Q37373807
Transcription elongation factor ELL2 directs immunoglobulin secretion in plasma cells by stimulating altered RNA processing.Q37408113
Steroidogenic factor 1 promotes aggressive growth of castration-resistant prostate cancer cells by stimulating steroid synthesis and cell proliferationQ37479334
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)123-136
P577publication date2017-11-01
P1433published inJournal of EndocrinologyQ6295150
P1476titleConditional deletion of ELL2 induces murine prostate intraepithelial neoplasia
P478volume235

Reverse relations

cites work (P2860)
Q90070043Anti-apoptotic factor Birc3 is up-regulated by ELL2 knockdown and stimulates proliferation in LNCaP cells
Q64087636Association of High miR-182 Levels with Low-Risk Prostate Cancer
Q61455990Concurrent EAF2 and ELL2 loss phenocopies individual EAF2 or ELL2 loss in prostate cancer cells and murine prostate
Q92961694Conditional Deletion of Eaf1 Induces Murine Prostatic Intraepithelial Neoplasia in Mice
Q47359744ELL2 regulates DNA non-homologous end joining (NHEJ) repair in prostate cancer cells.
Q90227095Regulation of ELL2 stability and polyubiquitination by EAF2 in prostate cancer cells