Development of a reactive stroma associated with prostatic intraepithelial neoplasia in EAF2 deficient mice

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Development of a reactive stroma associated with prostatic intraepithelial neoplasia in EAF2 deficient mice is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2013PLoSO...879542P
P356DOI10.1371/JOURNAL.PONE.0079542
P932PMC publication ID3832612
P698PubMed publication ID24260246
P5875ResearchGate publication ID258826077

P50authorBrian W. SimonsQ55381217
Javid A DarQ57046456
Laura E PascalQ57144929
Khalid Z. MasoodiQ48235634
P2093author name stringDan Wang
Xinhui Wang
Zhou Wang
Anil V Parwani
Yujuan Wang
Luyuan Li
Junkui Ai
Lora H Rigatti
Kurtis Eisermann
Benjamin J Davies
Hei M Ma
Katherine J O'Malley
Michael M Ittman
P2860cites workVascular endothelial growth factor expression and tumor angiogenesis are regulated by androgens in hormone responsive human prostate carcinoma: evidence for androgen dependent destabilization of vascular endothelial growth factor transcriptsQ73436686
Interfocal heterogeneity of PTEN/MMAC1 gene alterations in multiple metastatic prostate cancer tissuesQ74093343
Thrombospondin-1, vascular endothelial growth factor and fibroblast growth factor-2 are key functional regulators of angiogenesis in the prostateQ77359737
Inhibition of transforming growth factor-beta activity decreases angiogenesis in a human prostate cancer-reactive stroma xenograft modelQ78469525
Inducible prostate intraepithelial neoplasia with reversible hyperplasia in conditional FGFR1-expressing miceQ79370200
ADAMTS1, a putative anti-angiogenic factor, is decreased in human prostate cancerQ84065037
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesisQ24681977
Continuous cultures of fused cells secreting antibody of predefined specificityQ26776979
PTEN: one gene, many syndromesQ28203387
Androgens repress the expression of the angiogenesis inhibitor thrombospondin-1 in normal and neoplastic prostateQ28568984
Suppression of prostate tumor growth by U19, a novel testosterone-regulated apoptosis inducerQ28587720
U19/Eaf2 knockout causes lung adenocarcinoma, B-cell lymphoma, hepatocellular carcinoma and prostatic intraepithelial neoplasiaQ28590029
Practical aspects of planning, building, and interpreting tissue microarrays: the Cooperative Prostate Cancer Tissue Resource experienceQ30483391
Androgen regulation of spermidine synthase expression in the rat prostateQ31040745
The expression of androgen-responsive genes is up-regulated in the epithelia of benign prostatic hyperplasiaQ33493120
U19/Eaf2 binds to and stabilizes von hippel-lindau proteinQ33590977
PrimerBank: a resource of human and mouse PCR primer pairs for gene expression detection and quantificationQ33600700
Tumor suppressor U19/EAF2 regulates thrombospondin-1 expression via p53Q33604141
CD90/THY1 is overexpressed in prostate cancer-associated fibroblasts and could serve as a cancer biomarkerQ33609625
The effects of aging on the molecular and cellular composition of the prostate microenvironmentQ33687098
TGF-β1 induces an age-dependent inflammation of nerve ganglia and fibroplasia in the prostate gland stroma of a novel transgenic mouseQ33741877
VHL and PTEN loss coordinate to promote mouse liver vascular lesionsQ33862155
Plasma fibronectin promotes lung metastasis by contributions to fibrin clots and tumor cell invasionQ33892041
The effects of androgen deprivation on the prostate gland: cell death mediated by vascular regressionQ34045475
Reactive stroma as a predictor of biochemical-free recurrence in prostate cancerQ34272599
Derivation of androgen-independent human LNCaP prostatic cancer cell sublines: role of bone stromal cellsQ34340236
Reactive stroma in prostate cancer progressionQ34429976
Determining prostate cancer-specific death through quantification of stromogenic carcinoma area in prostatectomy specimensQ34756267
EAF2 loss enhances angiogenic effects of Von Hippel-Lindau heterozygosity on the murine liver and prostateQ35161330
Tumor progression: the effects of thrombospondin-1 and -2.Q35749722
Androgen deprivation induces rapid involution and recovery of human prostate vasculatureQ35760385
Hormonal, cellular, and molecular regulation of normal and neoplastic prostatic developmentQ36017017
Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expressionQ36067596
Genes regulated by androgen in the rat ventral prostateQ36715055
Gene Expression Profiling Reveals Regulation of ERK Phosphorylation by Androgen-Induced Tumor Suppressor U19/EAF2 in the Mouse Prostate.Q37373807
Reactive stroma in human prostate cancer: induction of myofibroblast phenotype and extracellular matrix remodeling.Q38362968
Thrombospondin-1, vascular endothelial growth factor expression and their relationship with p53 status in prostate cancer and benign prostatic hyperplasiaQ38457725
Differential Inductive Signaling of CD90 Prostate Cancer-Associated Fibroblasts Compared to Normal Tissue Stromal Mesenchyme Cells.Q39556027
Crucial role of the sarcoplasmic reticulum in the developmental regulation of Ca2+ transients and contraction in cardiomyocytes derived from embryonic stem cells.Q40358000
Loss of a small region around the PTEN locus is a major chromosome 10 alteration in prostate cancer xenografts and cell linesQ40597735
Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epitheliumQ40923257
Profiling molecular targets of TGF-beta1 in prostate fibroblast-to-myofibroblast transdifferentiationQ44320388
Purification of murine IgG monoclonal antibodies by precipitation with caprylic acid: comparison with other methods of purificationQ44966383
A crucial role for forebrain adenosine A(2A) receptors in amphetamine sensitizationQ45189219
The prostatic environment suppresses growth of androgen-independent prostate cancer xenografts: an effect influenced by testosterone.Q46033903
Independent association of angiogenesis index with outcome in prostate cancerQ46071411
Expression of murine ELL‐associated factor 2 (Eaf2) is developmentally regulatedQ46383343
A method to generate antigen-specific mAb capable of staining formalin-fixed, paraffin-embedded tissue sectionsQ46493041
Tenascin-C expression in prostatic intraepithelial neoplasia (PIN): a marker of progression?Q47689089
A set of novel tadpole specific genes expressed only in the epidermis are down-regulated by thyroid hormone during Xenopus laevis metamorphosisQ48053838
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectintraepithelial neoplasiaQ6058399
prostatic intraepithelial neoplasiaQ54911767
P304page(s)e79542
P577publication date2013-11-18
P1433published inPLOS OneQ564954
P1476titleDevelopment of a reactive stroma associated with prostatic intraepithelial neoplasia in EAF2 deficient mice
P478volume8

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cites work (P2860)
Q47657085Combined Loss of EAF2 and p53 Induces Prostate Carcinogenesis in Male Mice.
Q61455990Concurrent EAF2 and ELL2 loss phenocopies individual EAF2 or ELL2 loss in prostate cancer cells and murine prostate
Q92961694Conditional Deletion of Eaf1 Induces Murine Prostatic Intraepithelial Neoplasia in Mice
Q47701028Conditional deletion of ELL2 induces murine prostate intraepithelial neoplasia
Q52666493EAF2 and p53 Co-Regulate STAT3 Activation in Prostate Cancer.
Q90643584EAF2 loss induces prostatic intraepithelial neoplasia from luminal epithelial cells in mice
Q36661580EAF2 mediates germinal centre B-cell apoptosis to suppress excessive immune responses and prevent autoimmunity.
Q37746393EAF2 regulates DNA repair through Ku70/Ku80 in the prostate.
Q53421985Reactive stroma in the prostate during late life: The role of microvasculature and antiangiogenic therapy influences.
Q90227095Regulation of ELL2 stability and polyubiquitination by EAF2 in prostate cancer cells
Q37301786Regulation of tumor suppressor EAF2 polyubiquitination by ELL1 and SIAH2 in prostate cancer cells

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