Thrombospondin-1, vascular endothelial growth factor and fibroblast growth factor-2 are key functional regulators of angiogenesis in the prostate

scientific article published on 01 December 2001

Thrombospondin-1, vascular endothelial growth factor and fibroblast growth factor-2 are key functional regulators of angiogenesis in the prostate is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/PROS.10025
P698PubMed publication ID11746276

P2093author name stringS E Crawford
S C Campbell
N P Bouck
M R Pins
F K Reiher
J A Doll
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Vascular density is a predictor of cancer-specific survival in prostatic carcinomaQ73690891
Changes in growth factor expression in the ageing prostate may disrupt epithelial-stromal homeostasisQ74175806
Expression of multiple angiogenic cytokines in cultured normal human prostate epithelial cells: predominance of vascular endothelial growth factorQ74601078
Transforming growth factor beta1 is associated with angiogenesis, metastasis, and poor clinical outcome in prostate cancerQ77164555
Inactivation of the PTEN tumor suppressor gene is associated with increased angiogenesis in clinically localized prostate carcinomaQ77340398
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FGF7 and FGF2 are increased in benign prostatic hyperplasia and are associated with increased proliferationQ78015006
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Peptides derived from two separate domains of the matrix protein thrombospondin-1 have anti-angiogenic activityQ24674570
Pigment epithelium-derived factor: a potent inhibitor of angiogenesisQ28139159
VEGF overexpression in clinically localized prostate tumors and neuropilin-1 overexpression in metastatic formsQ28141270
Testosterone induces vascular endothelial growth factor synthesis in the ventral prostate in castrated ratsQ28373686
Thrombospondin-1 is a major activator of TGF-beta1 in vivoQ28513856
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesisQ29547178
Endothelial cell death, angiogenesis, and microvascular function after castration in an androgen-dependent tumor: role of vascular endothelial growth factorQ33556391
What might a stromal response mean to prostate cancer progression?Q33715210
A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondinQ33763790
Growth factors and epithelial-stromal interactions in prostate cancer developmentQ33955332
Distinct CXC chemokines mediate tumorigenicity of prostate cancer cellsQ35786924
Fibroblast growth factor-2 (FGF-2) induces vascular endothelial growth factor (VEGF) expression in the endothelial cells of forming capillaries: an autocrine mechanism contributing to angiogenesisQ36256017
A human fibrosarcoma inhibits systemic angiogenesis and the growth of experimental metastases via thrombospondin-1.Q37402504
Microvessel density predicts survival in prostate cancer patients subjected to watchful waitingQ38470808
Angiogenesis and prostate cancer: in vivo and in vitro expression of angiogenesis factors by prostate cancer cellsQ38472948
Evidence of independent origin of multiple tumors from patients with prostate cancerQ38529357
Optimized microvessel density analysis improves prediction of cancer stage from prostate needle biopsiesQ39424954
Vascular endothelial growth factor (VEGF) expression in prostatic tumours and its relationship to neuroendocrine cellsQ39999738
The application of an anti-angiogenic gene (thrombospondin-1) in the treatment of human prostate cancer xenograftsQ40823128
Neutralizing anti-vascular endothelial growth factor antibody completely inhibits angiogenesis and growth of human prostate carcinoma micro tumors in vivoQ41051413
The p53 tumor suppressor gene inhibits angiogenesis by stimulating the production of thrombospondin.Q41506143
Assay and purification of naturally occurring inhibitor of angiogenesisQ41703789
Influence of tumour size on human prostate tumour metastasis in athymic nude miceQ42374194
Topography of neovascularity in human prostate carcinomaQ42477426
Cathepsin B in angiogenesis of human prostate: an immunohistochemical and immunoelectron microscopic analysisQ42477520
Vascular endothelial growth factor expression and capillary architecture in high-grade PIN and prostate cancer in untreated and androgen-ablated patientsQ42492515
Endothelial cell proliferation activity in benign prostatic hyperplasia and prostate cancer: an in vitro model for assessmentQ47901241
Methylation and silencing of the Thrombospondin-1 promoter in human cancerQ48192580
Regulation of the activity of a new inhibitor of angiogenesis by a cancer suppressor gene.Q53516782
An analysis of microvessel density, androgen receptor, p53 and HER-2/neu expression and Gleason score in prostate cancer . preliminary results and therapeutic implications.Q54118091
Extracellular matrix-associated transforming growth factor-beta: role in cancer cell growth and invasion.Q54127845
Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitroQ67466166
Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1Q71644976
Association of transforming growth factor-β1 with prostate cancer: An immunohistochemical studyQ72067102
Tumor angiogenesis correlates with progression after radical prostatectomy but not with pathologic stage in Gleason sum 5 to 7 adenocarcinoma of the prostateQ73048634
P433issue4
P304page(s)293-305
P577publication date2001-12-01
P1433published inThe ProstateQ7758608
P1476titleThrombospondin-1, vascular endothelial growth factor and fibroblast growth factor-2 are key functional regulators of angiogenesis in the prostate
P478volume49

Reverse relations

cites work (P2860)
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