The MyD88-dependent, but not the MyD88-independent, pathway of TLR4 signaling is important in clearing nontypeable haemophilus influenzae from the mouse lung

scientific article published in November 2005

The MyD88-dependent, but not the MyD88-independent, pathway of TLR4 signaling is important in clearing nontypeable haemophilus influenzae from the mouse lung is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4049/JIMMUNOL.175.9.6042
P698PubMed publication ID16237099
P5875ResearchGate publication ID7529612

P50authorBruce BeutlerQ104592
Tom van der PollQ63136192
Kiyoshi TakedaQ87702013
Catharina W WielandQ114313281
Nico A MarisQ114313296
Sandrine FlorquinQ21264632
Kasper HoebeQ30503726
P2093author name stringShizuo Akira
P2860cites workTICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta inductionQ40675827
IRF3 mediates a TLR3/TLR4-specific antiviral gene programQ40700858
Haemophilus influenzae stimulates ICAM-1 expression on respiratory epithelial cellsQ40831617
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Platelet-activating factor receptor-deficient mice show an unaltered clearance of nontypeable Haemophilus influenzae from their respiratory tractQ45151947
Toll-like receptor 4 mediates innate immune responses to Haemophilus influenzae infection in mouse lungQ45882366
Cutting edge: myeloid differentiation factor 88 is essential for pulmonary host defense against Pseudomonas aeruginosa but not Staphylococcus aureus.Q47992063
Nontypeable Haemophilus influenzae in the lower respiratory tract of patients with chronic bronchitis.Q51340978
The pathogenicity of Haemophilus influenzae.Q53775934
The development of early host response to Pseudomonas aeruginosa lung infection is critically dependent on myeloid differentiation factor 88 in mice.Q54701109
Non–Mannose-capped Lipoarabinomannan Induces Lung Inflammation via Toll-like Receptor 2Q62516245
Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genesQ77137033
Community-acquired pneumoniaQ77464123
Differential involvement of IFN-beta in Toll-like receptor-stimulated dendritic cell activationQ78304878
Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transductionQ24291653
Toll-like receptor signallingQ24570126
LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIFQ24672442
Toll-like receptorsQ27860671
TIRAP: an adapter molecule in the Toll signaling pathwayQ28214613
TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathwayQ28505835
Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall componentsQ28511151
Identification of Lps2 as a key transducer of MyD88-independent TIR signallingQ28587545
Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathwayQ28592087
Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signalingQ28646137
Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated functionQ29617462
Simultaneous quantitation of 15 cytokines using a multiplexed flow cytometric assayQ30771030
Enhancement of clearance of bacteria from murine lungs by immunization with detoxified lipooligosaccharide from Moraxella catarrhalis conjugated to proteinsQ33597864
TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to toll-like receptor 4 TICAM-1 that induces interferon-beta.Q34266420
Host defense in respiratory infectionsQ34419617
Neisseria meningitidis lipooligosaccharide structure-dependent activation of the macrophage CD14/Toll-like receptor 4 pathwayQ36227394
Activation of NF-kappa B by nontypeable Hemophilus influenzae is mediated by toll-like receptor 2-TAK1-dependent NIK-IKK alpha /beta-I kappa B alpha and MKK3/6-p38 MAP kinase signaling pathways in epithelial cellsQ37114758
Toll-like receptor 2 plays a role in the early inflammatory response to murine pneumococcal pneumonia but does not contribute to antibacterial defenseQ39141528
Nontypable Haemophilus influenzae: a review of clinical aspects, surface antigens, and the human immune response to infection.Q39759511
Haemophilus influenzae porin induces Toll-like receptor 2-mediated cytokine production in human monocytes and mouse macrophages.Q40469752
Regulation of interactions of endotoxin with host cells.Q40597635
P433issue9
P407language of work or nameEnglishQ1860
P921main subjecttoll-like receptorQ408004
Haemophilus influenzaeQ1141979
P304page(s)6042-6049
P577publication date2005-11-01
P1433published inJournal of ImmunologyQ3521441
P1476titleThe MyD88-dependent, but not the MyD88-independent, pathway of TLR4 signaling is important in clearing nontypeable haemophilus influenzae from the mouse lung
P478volume175

Reverse relations

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