Time course of enzyme induction in humans: effect of pentobarbital on nortriptyline metabolism

scientific article published in July 1998

Time course of enzyme induction in humans: effect of pentobarbital on nortriptyline metabolism is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0009-9236(98)90018-2
P698PubMed publication ID9695715

P50authorJohan GabrielssonQ42890327
P2093author name stringSteiner E
Koike Y
von Bahr C
P2860cites workInfluence of route of administration on drug availabilityQ34226637
Genetic control of the phenobarbital-induced shortening of plasma antipyrine half-lives in man.Q34283194
Decreased plasma concentrations and clinical effects of alprenolol during combined treatment with pentobarbitone in hypertensionQ34416708
The influence of enzyme induction on polymorphic sparteine oxidationQ34447764
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Enzyme induction in the cytochrome P-450 systemQ38140216
The role of Barbie box sequences as cis-acting elements involved in the barbiturate-mediated induction of cytochromes P450BM-1 and P450BM-3 in Bacillus megateriumQ38297907
Influence of pentobarbital on metoprolol plasma levelsQ41731335
Partial metabolic clearances as determinants of the oral bioavailability of propranololQ42015699
First-pass metabolism of nortriptyline in manQ42597560
Pharmacokinetics: time-dependent changes--autoinduction of carbamazepine epoxidationQ43434705
Pentobarbital elimination in patients with poor renal functionQ53798758
Nortriptyline and debrisoquine hydroxylations in Ghanaian and Swedish subjects.Q53909148
Time course of phenobarbital and cimetidine mediated changes in hepatic drug metabolismQ61794937
Effect of pentobarbital on the disposition of alprenololQ67653134
Gas chromatographic determination of barbiturates by extractive alkylation and support coated open tubular column separationQ67697171
The mephenytoin oxidation polymorphism is partially responsible for the N-demethylation of imipramineQ68183654
Kinetic models of induction: I. Persistence of the inducing substanceQ69494403
Dose-dependent enzyme inductionQ69559046
Oxidation of tricyclic antidepressant drugs, debrisoquine and 7-ethoxyresorufin, by human liver preparationsQ69582092
Disposition of single oral doses of E-10-hydroxynortriptyline in healthy subjects, with some observations on pharmacodynamic effectsQ69588593
Propranolol's metabolism is determined by both mephenytoin and debrisoquin hydroxylase activitiesQ69936283
Urinary excretion of 6 beta-hydroxycortisol and the time course measurement of enzyme induction in manQ69948291
Correlation between nortriptyline and debrisoquine hydroxylation in the human liverQ70442262
E- and Z-10-hydroxylation of nortriptyline: relationship to polymorphic debrisoquine hydroxylationQ70823716
Multidose studies in the human metabolism of pentobarbitoneQ71265109
Steady-state plasma levels of nortriptyline in twins: influence of genetic factors and drug therapyQ71347970
Phenobarbital induces the 2-hydroxylation of desipramineQ71633126
Phenytoin causes a rapid increase in 6 beta-hydroxycortisol urinary excretion in humans--a putative measure of CYP3A inductionQ71895507
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)18-26
P577publication date1998-07-01
P1433published inClinical Pharmacology & TherapeuticsQ1101529
P1476titleTime course of enzyme induction in humans: effect of pentobarbital on nortriptyline metabolism
P478volume64

Reverse relations

cites work (P2860)
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Q36053763A mechanism-based pharmacokinetic-enzyme model for cyclophosphamide autoinduction in breast cancer patients
Q46233590A mechanism-based population pharmacokinetic model for characterizing time-dependent pharmacokinetics of midostaurin and its metabolites in human subjects
Q37219133Accidental Overdose of Oral Cyclosporine in Haematopoietic Stem Cell Transplantation: A Case Report and Literature Review
Q32117273Clinical pharmacokinetics and pharmacodynamics of ifosfamide and its metabolites
Q60596730Dealing with Time-Dependent Pharmacokinetics during the Early Clinical Development of a New Leukotriene B4 Synthesis Inhibitor
Q38372360Effects of Strong CYP3A Inhibition and Induction on the Pharmacokinetics of Ixazomib, an Oral Proteasome Inhibitor: Results of Drug-Drug Interaction Studies in Patients With Advanced Solid Tumors or Lymphoma and a Physiologically Based Pharmacokinet
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Q40306549Mechanisms and Consequences of Drug-Drug Interactions
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Q28081063Pattern Recognition in Pharmacokinetic Data Analysis
Q46922851Pharmacodynamics of carbamazepine-mediated induction of CYP3A4, CYP1A2, and Pgp as assessed by probe substrates midazolam, caffeine, and digoxin
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Q44872854Population pharmacokinetics of artesunate and dihydroartemisinin during long-term oral administration of artesunate to patients with metastatic breast cancer.
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