Phenytoin causes a rapid increase in 6 beta-hydroxycortisol urinary excretion in humans--a putative measure of CYP3A induction

scientific article published on 01 March 1995

Phenytoin causes a rapid increase in 6 beta-hydroxycortisol urinary excretion in humans--a putative measure of CYP3A induction is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/JPS.2600840305
P698PubMed publication ID7616365

P2093author name stringG R Peters
J C Fleishaker
L K Pearson
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectphenytoinQ410400
P304page(s)292-294
P577publication date1995-03-01
P1433published inJournal of Pharmaceutical SciencesQ3186933
P1476titlePhenytoin causes a rapid increase in 6 beta-hydroxycortisol urinary excretion in humans--a putative measure of CYP3A induction
P478volume84

Reverse relations

cites work (P2860)
Q34979818A review of the common properties of drugs with idiosyncratic hepatotoxicity and the "multiple determinant hypothesis" for the manifestation of idiosyncratic drug toxicity.
Q28363552A single dose of methadone inhibits cytochrome P-4503A activity in healthy volunteers as assessed by the urinary cortisol ratio
Q77481302Comment: troglitazone drug interactions
Q43793296DEET (N,N-diethyl-m-toluamide) alone and in combination with permethrin increased urinary excretion of 6beta-hydroxycortisol in rats, a marker of hepatic CYP3A induction
Q33742243Differential kinetics of phenytoin in elderly patients.
Q44484816Drug interaction potential of soy extract and Panax ginseng
Q44415284Effect of intrapatient dosage escalation of irinotecan on its pharmacokinetics in pediatric patients who have high-grade gliomas and receive enzyme-inducing anticonvulsant therapy
Q36887501Experimental models for evaluating enzyme induction potential of new drug candidates in animals and humans and a strategy for their use.
Q42106492Gefitinib-phenytoin interaction is not correlated with the C-erythromycin breath test in healthy male volunteers
Q60705900Imipramine demethylation in vivo: Impact of CYP1A2, CYP2C19, and CYP3A4*
Q74277096Liquid chromatographic determination of urinary 6beta-hydroxycortisol to assess cytochrome p-450 3A activity in HIV positive pregnant women
Q52575640Metabolism of anabolic steroids by recombinant human cytochrome P450 enzymes. Gas chromatographic-mass spectrometric determination of metabolites.
Q44237138Microsomal enzyme induction and clinical aggravation of porphyria: the evaluation of human urinary 6beta-hydroxycortisol/cortisol ratio as the index of hepatic CYP3A4 activity
Q73469872Phenytoin and electric shock-induced apoptosis in rat peripheral blood lymphocytes
Q35596516Population pharmacokinetics of oral high-dose busulfan in adult patients undergoing hematopoietic stem cell transplantation
Q47266083Population pharmacokinetics of tirilazad: effects of weight, gender, concomitant phenytoin, and subarachnoid hemorrhage
Q37271469Role of intravenous levetiracetam in seizure prophylaxis of severe traumatic brain injury patients
Q48121272Seizures and Choice of Antiepileptic Drugs Following Subarachnoid Hemorrhage: A Review
Q55426998The cytochrome P450 isoenzyme and some new opportunities for the prediction of negative drug interaction in vivo.
Q47722116Time course of enzyme induction in humans: effect of pentobarbital on nortriptyline metabolism
Q33588554Troglitazone: a review of its use in the management of type 2 diabetes mellitus
Q35579020Urinary 6?-hydroxycortisol: a validated test for evaluating drug induction or drug inhibition mediated through CYP3A in humans and in animals

Search more.