Altered expression and molecular abnormalities of cell-cycle-regulatory proteins in rhabdomyosarcoma

scientific article published in June 2004

Altered expression and molecular abnormalities of cell-cycle-regulatory proteins in rhabdomyosarcoma is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/MODPATHOL.3800101
P698PubMed publication ID15098008
P5875ResearchGate publication ID8606361

P2093author name stringHidetaka Yamamoto
Yoshinao Oda
Masazumi Tsuneyoshi
Sachiyo Suita
Yukiko Takahashi
Sadafumi Tamiya
Ken-Ichi Kawaguchi
P2860cites workThe mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivationQ28280958
Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53Q29615851
Mechanisms of p53 loss in human sarcomasQ33722859
Germline p53 mutations are frequently detected in young children with rhabdomyosarcomaQ34207682
Molecular pathogenesis of rhabdomyosarcomaQ34779149
P53 mutation and MDM2 amplification frequency in pediatric rhabdomyosarcoma tumors and cell linesQ40864851
Alterations of cell cycle regulators affecting the RB pathway in nonfamilial retinoblastomaQ43623316
Evaluation of proliferative index and cell cycle protein expression in choroid plexus tumors in children.Q44925915
MDM2 amplification, P53 mutation, and accumulation of the P53 gene product in malignant fibrous histiocytomaQ44984040
Immunohistochemical expression of cell cycle proteins E2F-1, Cdk-2, Cyclin E, p27(kip1), and Ki-67 in normal placenta and gestational trophoblastic disease.Q45947856
Retinoblastoma protein expression and MIB-1 correlate with survival of patients with malignant astrocytomaQ48657987
Immunohistochemical detection of p53 protein in rhabdomyosarcoma: association with clinicopathological features and outcome.Q50968542
High prognostic significance of Mdm2/p53 co-overexpression in soft tissue sarcomas of the extremitiesQ56566036
Analysis of alterations in the retinoblastoma gene and tumor grade in bone and soft-tissue sarcomasQ68184562
Altered expression of the retinoblastoma gene product in human sarcomasQ68593145
Expression of the retinoblastoma susceptibility gene in childhood rhabdomyosarcomasQ70525044
Frequent occurrence of p53 mutations in rhabdomyosarcoma and leiomyosarcoma, but not in fibrosarcoma and malignant neural tumorsQ71513567
Molecular abnormalities of p53, MDM2, and H-ras in synovial sarcomaQ73009035
Loss of RB and MTS1/CDKN2 (p16) expression in human sarcomasQ73622335
Mutation analysis of p53 gene in childhood malignant solid tumorsQ73622699
Molecular analysis of p53, MDM2, and H-ras genes in osteosarcoma and malignant fibrous histiocytoma of bone in patients older than 40 yearsQ74615780
H-ras and K-ras mutations in soft tissue sarcoma: comparative studies of sarcomas from Korean and American patientsQ77953988
p53 and mdm-2 expression in Rhabdomyosarcoma of childhood and adolescence: clinicopathologic study by the Kiel Pediatric Tumor Registry and the German Cooperative Soft Tissue Sarcoma StudyQ78947823
P433issue6
P921main subjectrhabdomyosarcomaQ1898141
P304page(s)660-669
P577publication date2004-06-01
P1433published inModern PathologyQ15724578
P1476titleAltered expression and molecular abnormalities of cell-cycle-regulatory proteins in rhabdomyosarcoma
P478volume17

Reverse relations

cites work (P2860)
Q56997205A magnetic electrochemical immunosensor for the detection of phosphorylated p53 based on enzyme functionalized carbon nanospheres with signal amplification
Q55265062A review of soft-tissue sarcomas: translation of biological advances into treatment measures.
Q37580831Advances in pediatric rhabdomyosarcoma characterization and disease model development
Q36588372Alveolar rhabdomyosarcoma - The molecular drivers of PAX3/7-FOXO1-induced tumorigenesis
Q37598848Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function.
Q34235576Anaplastic rhabdomyosarcoma in TP53 germline mutation carriers
Q36093810CDK4 Amplification Reduces Sensitivity to CDK4/6 Inhibition in Fusion-Positive Rhabdomyosarcoma
Q36240990Cyclin D1 as a diagnostic immunomarker for endometrial stromal sarcoma with YWHAE-FAM22 rearrangement
Q37881290Developmental origins of fusion-negative rhabdomyosarcomas.
Q34580128Evidence for an unanticipated relationship between undifferentiated pleomorphic sarcoma and embryonal rhabdomyosarcoma
Q33819295Fine needle aspiration biopsy diagnosis of dedifferentiated liposarcoma: Cytomorphology and MDM2 amplification by FISH
Q24319144IRIZIO: a novel gene cooperating with PAX3-FOXO1 in alveolar rhabdomyosarcoma (ARMS)
Q83051301Immunoglobulin G is present in a wide variety of soft tissue tumors and correlates well with proliferation markers and tumor grades
Q45947620Immunostaining for peroxisome proliferator gamma distinguishes dedifferentiated liposarcoma from other retroperitoneal sarcomas.
Q34162514Impaired Wnt signaling in embryonal rhabdomyosarcoma cells from p53/c-fos double mutant mice
Q30411722Lineage of origin in rhabdomyosarcoma informs pharmacological response
Q35897781Low Prevalence of TP53 Mutations and MDM2 Amplifications in Pediatric Rhabdomyosarcoma
Q34999483MI-63: a novel small-molecule inhibitor targets MDM2 and induces apoptosis in embryonal and alveolar rhabdomyosarcoma cells with wild-type p53.
Q54239289MYCN and survivin cooperatively contribute to malignant transformation of fibroblasts.
Q26852728Mechanisms of impaired differentiation in rhabdomyosarcoma
Q42947899Mice lacking dystrophin or alpha sarcoglycan spontaneously develop embryonal rhabdomyosarcoma with cancer-associated p53 mutations and alternatively spliced or mutant Mdm2 transcripts
Q37630588Molecular and cellular biology of rhabdomyosarcoma.
Q37343475Noonan, Costello and cardio-facio-cutaneous syndromes: dysregulation of the Ras-MAPK pathway
Q30437251PDGFR-A is a therapeutic target in alveolar rhabdomyosarcoma
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Q34255856Rb1 loss modifies but does not initiate alveolar rhabdomyosarcoma
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Q48104644Ultraviolet A eye irradiation ameliorates colon carcinoma induced by azoxymethane and dextran sodium sulfate through β-endorphin and methionine-enkephalin.

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