Trigonelline insulates against oxidative stress, proinflammatory cytokines and restores BDNF levels in lipopolysaccharide induced cognitive impairment in adult mice

scientific article published on 26 December 2017

Trigonelline insulates against oxidative stress, proinflammatory cytokines and restores BDNF levels in lipopolysaccharide induced cognitive impairment in adult mice is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/S11011-017-0147-5
P2888exact matchhttps://scigraph.springernature.com/pub.10.1007/s11011-017-0147-5
P698PubMed publication ID29277879

P2093author name stringRenuka Munshi
Amrita A Chowdhury
Archana R Juvekar
Nitin B Gawali
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Trigonelline and diosgenin attenuate ER stress, oxidative stress-mediated damage in pancreas and enhance adipose tissue PPARγ activity in type 2 diabetic ratsQ87460136
In vitro antiglycating effect and in vivo neuroprotective activity of Trigonelline in d-galactose induced cognitive impairmentQ87871021
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Inhibition of the Nrf2 transcription factor by the alkaloid trigonelline renders pancreatic cancer cells more susceptible to apoptosis through decreased proteasomal gene expression and proteasome activityQ39251887
Acetylcholinesterase enzyme inhibitory potential of standardized extract of Trigonella foenum graecum L and its constituentsQ39301320
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BDNF mRNA is decreased in the hippocampus of individuals with Alzheimer's diseaseQ43727698
Trigonelline ameliorates oxidative stress in type 2 diabetic Goto-Kakizaki ratsQ44318693
LPS-induced oxidative stress and inflammatory reaction in the rat striatumQ45032073
Neurobehavioral assessment of hydroalcoholic extract of Trigonella foenum-graecum seeds in rodent models of Parkinson's disease.Q45383852
Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease.Q46303283
Decaffeinated coffee prevents scopolamine-induced memory impairment in ratsQ46347525
Coffee improves auditory neuropathy in diabetic miceQ46513736
Microglial phagocytosis induced by fibrillar beta-amyloid and IgGs are differentially regulated by proinflammatory cytokines.Q46691360
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Brain inflammatory response induced by intracerebroventricular infusion of lipopolysaccharide: an immunohistochemical studyQ47985685
Trigonelline-induced neurite outgrowth in human neuroblastoma SK-N-SH cellsQ48139437
Trigonelline and vildagliptin antidiabetic effect: improvement of insulin signalling pathway.Q48151784
Silibinin ameliorates LPS-induced memory deficits in experimental animals.Q48439199
Peripheral immune activation by lipopolysaccharide decreases neurotrophins in the cortex and hippocampus in rats.Q48880251
Acetylcholinesterase accelerates assembly of amyloid-beta-peptides into Alzheimer's fibrils: possible role of the peripheral site of the enzyme.Q49047282
Acute nicotine treatment attenuates lipopolysaccharide-induced cognitive dysfunction by increasing BDNF expression and inhibiting neuroinflammation in the rat hippocampus.Q50571712
Obovatol attenuates LPS-induced memory impairments in mice via inhibition of NF-κB signaling pathway.Q50981778
Effects of morphine and its withdrawal on Y-maze spatial recognition memory in mice.Q51974051
Role of interleukin 6 and alpha-globulins in differentiating Alzheimer and vascular dementias.Q53324311
Trigonelline isolated from fenugreek seed protects against isoproterenol-induced myocardial injury through down-regulation of Hsp27 and αB-crystallin.Q54404611
Region-Specific Neurotrophin Imbalances in Alzheimer DiseaseQ57833020
P921main subjectlipopolysaccharideQ421804
cognitive dysfunctionQ57859955
P577publication date2017-12-26
P1433published inMetabolic Brain DiseaseQ15764352
P1476titleTrigonelline insulates against oxidative stress, proinflammatory cytokines and restores BDNF levels in lipopolysaccharide induced cognitive impairment in adult mice

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cites work (P2860)
Q91972365Herbal Formula Fo Shou San Attenuates Alzheimer's Disease-Related Pathologies via the Gut-Liver-Brain Axis in APP/PS1 Mouse Model of Alzheimer's Disease
Q100428080Trigonelline recovers memory function in Alzheimer's disease model mice: evidence of brain penetration and target molecule
Q92298173Trigonelline reduced diabetic nephropathy and insulin resistance in type 2 diabetic rats through peroxisome proliferator-activated receptor-γ

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