Gene-set analysis shows association between FMRP targets and autism spectrum disorder

scientific article

Gene-set analysis shows association between FMRP targets and autism spectrum disorder is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/EJHG.2017.55
P2888exact matchhttps://scigraph.springernature.com/pub.10.1038/ejhg.2017.55
P932PMC publication ID5520067
P698PubMed publication ID28422133

P50authorArija G JansenQ92190837
Danielle PosthumaQ21257977
Tinca PoldermanQ42634768
Matthijs VerhageQ56905118
P2093author name stringAugust B Smit
Frank C Verhulst
Gwen C Dieleman
P2860cites workDSM-5Q3064664
Biological insights from 108 schizophrenia-associated genetic lociQ24561833
Functional impact of global rare copy number variation in autism spectrum disordersQ24596191
Common genetic variants on 5p14.1 associate with autism spectrum disordersQ24603204
Rare structural variation of synapse and neurotransmission genes in autismQ24608775
Mitochondrial dysfunction in autism spectrum disorders: a systematic review and meta-analysisQ24630557
FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autismQ24631425
A genome-wide association study of autism reveals a common novel risk locus at 5p14.1Q24634148
PLINK: a tool set for whole-genome association and population-based linkage analysesQ24677407
Fragile X spectrum disordersQ26824376
The role of glutamate and its receptors in autism and the use of glutamate receptor antagonists in treatmentQ26998975
The FMRP regulon: from targets to disease convergenceQ27014002
A genome-wide association study of autism using the Simons Simplex Collection: Does reducing phenotypic heterogeneity in autism increase genetic homogeneity?Q27326701
FMRP targets distinct mRNA sequence elements to regulate protein expressionQ28117931
Synaptic, transcriptional and chromatin genes disrupted in autismQ28250800
The contribution of de novo coding mutations to autism spectrum disorderQ28250812
Meta-analysis of the heritability of human traits based on fifty years of twin studiesQ28262090
Patterns and rates of exonic de novo mutations in autism spectrum disordersQ28264242
Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndromeQ28273791
Individual common variants exert weak effects on the risk for autism spectrum disordersQ28943296
A genome-wide scan for common alleles affecting risk for autismQ28943508
Sporadic autism exomes reveal a highly interconnected protein network of de novo mutationsQ29030218
De Novo Gene Disruptions in Children on the Autistic SpectrumQ29394534
De novo mutations revealed by whole-exome sequencing are strongly associated with autismQ29547269
MAGMA: generalized gene-set analysis of GWAS dataQ30935493
A genome-wide association study of autism incorporating autism diagnostic interview-revised, autism diagnostic observation schedule, and social responsiveness scaleQ33161703
A genome-wide association study of social and non-social autistic-like traits in the general population using pooled DNA, 500 K SNP microarrays and both community and diagnosed autism replication samplesQ33556118
Functional gene group analysis reveals a role of synaptic heterotrimeric G proteins in cognitive abilityQ33645949
Convergence of genes and cellular pathways dysregulated in autism spectrum disordersQ33794546
Genetic architectures of psychiatric disorders: the emerging picture and its implicationsQ33949729
A polygenic burden of rare disruptive mutations in schizophreniaQ34060200
Age-dependent brain gene expression and copy number anomalies in autism suggest distinct pathological processes at young versus mature agesQ34211584
INRICH: interval-based enrichment analysis for genome-wide association studiesQ34269233
Insights into Autism Spectrum Disorder Genomic Architecture and Biology from 71 Risk LociQ34495555
De novo mutations in schizophrenia implicate synaptic networksQ34540372
A noise-reduction GWAS analysis implicates altered regulation of neurite outgrowth and guidance in autismQ34557745
Copy number variation in schizophrenia in SwedenQ34742638
Pathway analyses implicate glial cells in schizophreniaQ35107323
Regulation of molecular pathways in the Fragile X Syndrome: insights into Autism Spectrum DisordersQ35196556
Functional gene group analysis identifies synaptic gene groups as risk factor for schizophrenia.Q36253911
Myelination-related genes are associated with decreased white matter integrity in schizophreniaQ36591201
Pathway analysis of seven common diseases assessed by genome-wide associationQ37014849
Impaired activity-dependent neural circuit assembly and refinement in autism spectrum disorder genetic modelsQ37564195
Impaired mitochondrial function in psychiatric disordersQ38003304
The glial perspective of autism spectrum disordersQ38168409
The role of de novo mutations in the genetics of autism spectrum disordersQ38178892
Recent advances in the genetics of autism spectrum disorderQ38462559
Gene set analysis: A step-by-step guideQ38522741
The statistical properties of gene-set analysisQ38806240
Comorbid Symptomology in Adults with Autism Spectrum Disorder and Intellectual Disability.Q41501872
Up-Regulation of Oligodendrocyte Lineage Markers in the Cerebellum of Autistic Patients: Evidence from Network Analysis of Gene Expression.Q50309596
P433issue7
P921main subjectautismQ38404
autism spectrum disorderQ1436063
P304page(s)863-868
P577publication date2017-04-19
P1433published inEuropean Journal of Human GeneticsQ2155433
P1476titleGene-set analysis shows association between FMRP targets and autism spectrum disorder
P478volume25

Reverse relations

cites work (P2860)
Q64244012Analysis of a Sardinian Multiplex Family with Autism Spectrum Disorder Points to Post-Synaptic Density Gene Variants and Identifies as a Functionally Relevant Candidate Gene
Q64081528Family History of Mental and Neurological Disorders and Risk of Autism
Q100737121Genetic association of FMRP targets with psychiatric disorders
Q88956981Multi-marker analysis of genomic annotation on gastric cancer GWAS data from Chinese populations
Q90574779Reduced neonatal brain-derived neurotrophic factor is associated with autism spectrum disorders
Q92065725Synaptic and brain-expressed gene sets relate to the shared genetic risk across five psychiatric disorders
Q100751528The influence of common polygenic risk and gene sets on social skills group training response in autism spectrum disorder
Q92052257The mTOR Signaling Pathway Activity and Vitamin D Availability Control the Expression of Most Autism Predisposition Genes
Q90597084Widespread RNA editing dysregulation in brains from autistic individuals

Search more.