Differential oxygen sensitivity of the K+-Cl- cotransporter in normal and sickle human red blood cells

scientific article published in August 1998

Differential oxygen sensitivity of the K+-Cl- cotransporter in normal and sickle human red blood cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1469-7793.1998.225BI.X
P932PMC publication ID2231113
P698PubMed publication ID9679176
P5875ResearchGate publication ID13606272

P2093author name stringJ C Ellory
J S Gibson
P F Speake
P2860cites workThe function of calcium in the potassium permeability of human erythrocytesQ28184377
Inhibition of K+ efflux and dehydration of sickle cells by [(dihydroindenyl)oxy]alkanoic acid: an inhibitor of the K+ Cl- cotransport systemQ33868071
Effects of deoxygenation on active and passive Ca2+ transport and on the cytoplasmic Ca2+ levels of sickle cell anemia red cellsQ33908772
Erythrocyte K-Cl cotransport: properties and regulationQ35534126
The effects of sickling on ion transport. II. The effect of sickling on sodium and cesium transportQ36286980
Stochastic nature and red cell population distribution of the sickling-induced Ca2+ permeabilityQ37368255
Hemoglobin S gelation and sickle cell diseaseQ39672782
K+:Cl- cotransport: sulfhydryls, divalent cations, and the mechanism of volume activation in a red cellQ39850944
A mathematical model of the volume, pH, and ion content regulation in reticulocytes. Application to the pathophysiology of sickle cell dehydrationQ40339628
Evidence for a direct reticulocyte origin of dense red cells in sickle cell anemiaQ40339639
Osmotic effects of water compartments in protein polymersQ40410749
Regulation of Cl-dependent K transport by oxy-deoxyhemoglobin transitions in trout red cellsQ43614422
Selective inhibitors of KCl cotransport in human red cellsQ43654417
KCl Cotransport in HbAA and HbSS Red Cells: Activation by Intracellular Acidity and Disappearance During MaturationQ43777104
Deoxygenation inhibits the volume-stimulated, Cl(-)-dependent K+ efflux in SS and young AA cells: a cytosolic Mg2+ modulation.Q43805326
Effects of urea and oxygen tension on K flux in sickle cells.Q54142674
Volume-dependent and NEM-stimulated K+,Cl- transport is elevated in oxygenated SS, SC and CC human red cells.Q54428100
The effects of oxygenation upon the Cl-dependent K flux pathway in equine red cellsQ57251338
Na+ K+ pump and passive K+ transport in large and small red cell populations of anemic high and low K+ sheepQ67295823
Oxygenation-activated K fluxes in trout red blood cellsQ67586547
Rapid increase in red blood cell density driven by K:Cl cotransport in a subset of sickle cell anemia reticulocytes and discocytesQ67694355
Hemoglobin variants and activity of the (K+Cl-) cotransport system in human erythrocytesQ67732248
Demonstration of a [K+,Cl-]-cotransport system in human red cells by its sensitivity to [(dihydroindenyl)oxy]alkanoic acids: regulation of cell swelling and distinction from the bumetanide-sensitive [Na+,K+,Cl-]-cotransport systemQ68396356
Deoxygenation-induced cation fluxes in sickle cells: relationship between net potassium efflux and net sodium influxQ68407591
Deoxygenation permeabilizes sickle cell anaemia red cells to magnesium and reverses its gradient in the dense cellsQ68560168
Inhibition of K transport by divalent cations in sickle erythrocytesQ69441983
Evidence for the presence of volume-sensitive KCl transport in 'young' human red cellsQ69540419
Acid pH induces formation of dense cells in sickle erythrocytesQ69663626
The mechanism of in vitro formation of irreversibly sickled cells and modes of action of its inhibitorsQ70026551
Regulation of erythrocyte cation and water content in sickle cell anemiaQ70037500
Deoxygenation-induced cation fluxes in sickle cells. III. Cation selectivity and response to pH and membrane potentialQ70629863
Passive potassium transport in low potassium sheep red cells: dependence upon cell volume and chlorideQ71582391
Dehydration of transferrin receptor-positive sickle reticulocytes during continuous or cyclic deoxygenation: role of KCl cotransport and extracellular calciumQ71834818
Urea activation of K-Cl transport in human erythrocytesQ72198658
Role of protein phosphorylation in control of K flux pathways of trout red blood cellsQ72382889
Modulation of K(+)-Cl- cotransport in equine red blood cellsQ72584530
The involvement of the Ca-dependent K channel and of the KCl co-transport in sickle cell dehydration during cyclic deoxygenationQ72783174
K-Cl cotransport in rabbit red cells: further evidence for regulation by protein phosphatase type 1Q72948510
Urea-stimulated K-Cl cotransport in equine red blood cellsQ73204716
Effect of changes in respiratory blood parameters on equine red blood cell K-Cl cotransporterQ74065325
Oxygen-dependent K+ fluxes in sheep red cellsQ74315943
Passive sodium and potassium movements in sickle erythrocytesQ93603866
P407language of work or nameEnglishQ1860
P1104number of pages10
P304page(s)225-234
P577publication date1998-08-01
P1433published inJournal of PhysiologyQ7743612
P1476titleDifferential oxygen sensitivity of the K+-Cl- cotransporter in normal and sickle human red blood cells
P478volume511 ( Pt 1)

Reverse relations

cites work (P2860)
Q43662835A critical role of the strychnine-sensitive glycinergic system in spontaneous retinal waves of the developing rabbit.
Q45258621A model for fluid secretion in Rhodnius upper Malpighian tubules (UMT).
Q45200700Activation of ferret erythrocyte Na+-K+-2Cl- cotransport by deoxygenation
Q35980596Biochemical indicator of sickle cell disease: preliminary report from India
Q36540959Cation Homeostasis in Red Cells From Patients With Sickle Cell Disease Heterologous for HbS and HbC (HbSC Genotype).
Q36384751Characterization of the deoxyhemoglobin binding site on human erythrocyte band 3: implications for O2 regulation of erythrocyte properties
Q22009138Cloning, characterization, and chromosomal location of a novel human K+-Cl- cotransporter
Q43705401Direct estimate of 1:1 stoichiometry of K(+)-Cl(-) cotransport in rabbit erythrocytes
Q44308498Effect of 1-chloro-2,4-dinitrobenzene on K+ transport in normal and sickle human red blood cells
Q73084568Effect of dimethyl adipimidate on K+ transport and shape change in red blood cells from sickle cell patients
Q42090481Effect of intracellular magnesium and oxygen tension on K+-Cl- cotransport in normal and sickle human red cells
Q50466093Effects of 5-hydroxymethyl-2-furfural on the volume and membrane permeability of red blood cells from patients with sickle cell disease.
Q43792110GSH depletion, K-Cl cotransport, and regulatory volume decrease in high-K/high-GSH dog red blood cells
Q39390814In vivo rates of erythrocyte glutathione synthesis in adults with sickle cell disease.
Q35993299Ion transport pathology in the mechanism of sickle cell dehydration
Q43639884K(+) transport in red blood cells from human umbilical cord
Q47786564K+-Cl- cotransport: 'to be or not to be' oxygen sensitive
Q91804674K+-Cl- cotransporter 1 (KCC1): a housekeeping membrane protein that plays key supplemental roles in hematopoietic and cancer cells
Q73948162O(2)-dependent K(+) fluxes in trout red blood cells: the nature of O(2) sensing revealed by the O(2) affinity, cooperativity and pH dependence of transport
Q33726914Oxygen regulates the band 3-ankyrin bridge in the human erythrocyte membrane
Q64290557Oxygen tension–mediated erythrocyte membrane interactions regulate cerebral capillary hyperemia
Q74525939Oxygen-dependent K+ influxes in Mg2+-clamped equine red blood cells
Q34772272Oxygen-dependent cellular functions--why fishes and their aquatic environment are a prime choice of study.
Q35567943Pathological basis of symptoms and crises in sickle cell disorder: implications for counseling and psychotherapy
Q44435543Regulation of K-Cl cotransport by Syk and Src protein tyrosine kinases in deoxygenated sickle cells
Q36042361Regulation of K-Cl cotransport: from function to genes
Q57251327Regulation of Na+-K+-2Cl- cotransport in turkey red cells: the role of oxygen tension and protein phosphorylation
Q90621981Regulation of erythrocyte Na+/K+/2Cl- cotransport by an oxygen-switched kinase cascade
Q48327851Reversible binding of hemoglobin to band 3 constitutes the molecular switch that mediates O2 regulation of erythrocyte properties
Q55411797Squeezing for Life - Properties of Red Blood Cell Deformability.
Q92921024The Effect of Antioxidants on the Properties of Red Blood Cells From Patients With Sickle Cell Anemia
Q34734929The Properties of Red Blood Cells from Patients Heterozygous for HbS and HbC (HbSC Genotype)
Q35571006The clinical significance of K-Cl cotransport activity in red cells of patients with HbSC disease
Q41842805The effect of deoxygenation on whole-cell conductance of red blood cells from healthy individuals and patients with sickle cell disease.
Q64114706The effect of the antisickling compound GBT1118 on the permeability of red blood cells from patients with sickle cell anemia
Q48140044The super sickling haemoglobin HbS-Oman: a study of red cell sickling, K+ permeability and associations with disease severity in patients heterozygous for HbA and HbS-Oman (HbA/S-Oman genotype).
Q50732496Two different oxygen sensors regulate oxygen-sensitive K+ transport in crucian carp red blood cells.
Q35628941Urea stimulation of KCl cotransport induces abnormal volume reduction in sickle reticulocytes

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