| scholarly article | Q13442814 |
| P2093 | author name string | Dayalan Sampath | |
| Andrew M White | |||
| Yogendra H Raol | |||
| Robert Valdez | |||
| P2860 | cites work | Antiepileptic drugs and apoptotic neurodegeneration in the developing brain | Q24538604 |
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| KCNQ2 and KCNQ3 potassium channel genes in benign familial neonatal convulsions: expansion of the functional and mutation spectrum | Q28208104 | ||
| The KCNQ2 potassium channel: splice variants, functional and developmental expression. Brain localization and comparison with KCNQ3 | Q28289632 | ||
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| Early expression of GABA(A) receptor delta subunit in the neonatal rat hippocampus | Q30975308 | ||
| Neonatal hypoxic-ischemic encephalopathy: multimodality imaging findings | Q31068045 | ||
| Flupirtine shows functional NMDA receptor antagonism by enhancing Mg2+ block via activation of voltage independent potassium channels. Rapid communication. | Q33883701 | ||
| Parent-reported benefits of flupirtine in juvenile neuronal ceroid lipofuscinosis (Batten disease; CLN3) are not supported by quantitative data | Q33894023 | ||
| GABA itself promotes the developmental switch of neuronal GABAergic responses from excitation to inhibition. | Q33948016 | ||
| Flupirtine blocks apoptosis in batten patient lymphoblasts and in human postmitotic CLN3- and CLN2-deficient neurons | Q34121060 | ||
| Flupirtine: Clinical pharmacology | Q34272694 | ||
| Flupirtine, a re-discovered drug, revisited | Q34322776 | ||
| Clinical Neonatal Seizures are Independently Associated with Outcome in Infants at Risk for Hypoxic-Ischemic Brain Injury | Q34457628 | ||
| Bumetanide enhances phenobarbital efficacy in a rat model of hypoxic neonatal seizures | Q34638960 | ||
| Antiepileptic drug-induced neuronal cell death in the immature brain: effects of carbamazepine, topiramate, and levetiracetam as monotherapy versus polytherapy | Q34652321 | ||
| Flupirtine: pharmacology and clinical applications of a nonopioid analgesic and potentially neuroprotective compound. | Q34985534 | ||
| Metabolic activation and analgesic effect of flupirtine in healthy subjects, influence of the polymorphic NAT2, UGT1A1 and GSTP1. | Q35135974 | ||
| Sex differences in mechanisms and outcome of neonatal hypoxia-ischemia in rodent models: implications for sex-specific neuroprotection in clinical neonatal practice | Q35837825 | ||
| Unexpected frequent hepatotoxicity of a prescription drug, flupirtine, marketed for about 30 years | Q36111238 | ||
| Neonatal exposure to antiepileptic drugs disrupts striatal synaptic development | Q36170106 | ||
| Flupirtine effectively prevents development of acute neonatal seizures in an animal model of global hypoxia | Q36244749 | ||
| G-protein-gated Inwardly Rectifying Potassium Channels Modulate Respiratory Depression by Opioids | Q36586207 | ||
| Switch in the expression of rat GABAA-receptor subtypes during postnatal development: an immunohistochemical study | Q36739893 | ||
| Comparison of the long-term behavioral effects of neonatal exposure to retigabine or phenobarbital in rats | Q36788737 | ||
| Flupirtine as neuroprotective add-on therapy in autoimmune optic neuritis | Q36943102 | ||
| A KCNQ channel opener for experimental neonatal seizures and status epilepticus | Q37151699 | ||
| Evidence for an extended duration of GABA-mediated excitation in the developing male versus female hippocampus | Q37267931 | ||
| Anticonvulsant drug-induced cell death in the developing white matter of the rodent brain | Q37558928 | ||
| Profile of retigabine-induced neuronal apoptosis in the developing rat brain | Q37559363 | ||
| Flupirtine-induced liver injury--seven cases from the Berlin Case-control Surveillance Study and review of the German spontaneous adverse drug reaction reporting database | Q38173690 | ||
| Phenobarbital compared with phenytoin for the treatment of neonatal seizures. | Q38499446 | ||
| δ Subunit-containing GABAA receptors are preferred targets for the centrally acting analgesic flupirtine. | Q38849244 | ||
| Different response to antiepileptic drugs according to the type of epileptic events in a neonatal ischemia-reperfusion model | Q39044899 | ||
| Concomitant facilitation of GABAA receptors and KV7 channels by the non-opioid analgesic flupirtine. | Q39424563 | ||
| Protective effect of the KCNQ activator flupirtine on a model of repetitive febrile seizures | Q40315679 | ||
| The temporal characteristics of seizures in neonatal hypoxic ischemic encephalopathy treated with hypothermia | Q40319341 | ||
| Educational readiness of survivors of neonatal encephalopathy associated with birth asphyxia at term | Q41907919 | ||
| Electrographic seizures in neonates correlate with poor neurodevelopmental outcome | Q41924438 | ||
| KCNQ2 encephalopathy: emerging phenotype of a neonatal epileptic encephalopathy. | Q42501055 | ||
| Influence of flupirtine on a G-protein coupled inwardly rectifying potassium current in hippocampal neurones | Q42682171 | ||
| gamma-Aminobutyric acid(A) receptor subunit expression predicts functional changes in hippocampal dentate granule cells during postnatal development | Q43627925 | ||
| Prolonged seizures exacerbate perinatal hypoxic-ischemic brain damage | Q43745507 | ||
| Seizure-associated brain injury in term newborns with perinatal asphyxia. | Q43896003 | ||
| Age-dependent modulation of hippocampal excitability by KCNQ-channels | Q44308121 | ||
| M channels containing KCNQ2 subunits modulate norepinephrine, aspartate, and GABA release from hippocampal nerve terminals. | Q44737230 | ||
| KCNQ2 is a nodal K+ channel. | Q44755361 | ||
| The distribution of thirteen GABAA receptor subunit mRNAs in the rat brain. III. Embryonic and postnatal development | Q44767968 | ||
| GABAA receptor function in developing rat thalamic reticular neurons: whole cell recordings of GABA-mediated currents and modulation by clonazepam | Q45100995 | ||
| Conditional transgenic suppression of M channels in mouse brain reveals functions in neuronal excitability, resonance and behavior. | Q45194025 | ||
| Neonatal seizures: after all these years we still love what doesn't work | Q45309156 | ||
| Clinical spectrum of early onset epileptic encephalopathies caused by KCNQ2 mutation. | Q45406859 | ||
| Neonatal seizures: treatment and treatment variability in 31 United States pediatric hospitals | Q46139293 | ||
| Expression and function of KCNQ channels in larval zebrafish | Q46208968 | ||
| Low expression of Kv7/M channels facilitates intrinsic and network bursting in the developing rat hippocampus | Q46359359 | ||
| Long-term effects of diazepam and phenobarbital treatment during development on GABA receptors, transporters and glutamic acid decarboxylase | Q46414495 | ||
| Drug treatment of neonatal seizures by neonatologists and paediatric neurologists | Q46598254 | ||
| Epileptiform activity induced by pharmacologic reduction of M-current in the developing hippocampus in vitro | Q46897469 | ||
| Postnatal development of hippocampal dentate granule cell gamma-aminobutyric acidA receptor pharmacological properties. | Q48273202 | ||
| Effect of treatment of subclinical neonatal seizures detected with aEEG: randomized, controlled trial | Q48333649 | ||
| Does the onset of neonatal seizures correlate with the timing of fetal neurologic injury? | Q48344884 | ||
| Neuroprotective effect of topiramate on hypoxic ischemic brain injury in neonatal rats. | Q48456646 | ||
| Doxycycline treatment in a neonatal rat model of hypoxia-ischemia reduces cerebral tissue and white matter injury: a longitudinal magnetic resonance imaging study | Q48507468 | ||
| The current etiologic profile and neurodevelopmental outcome of seizures in term newborn infants | Q48595093 | ||
| Sex-dependent maturation of GABAA receptor-mediated synaptic events in rat substantia nigra reticulata | Q48617214 | ||
| The relationship between the onset of electrographic seizure activity after birth and the time of cerebral injury in utero | Q48961254 | ||
| Incidence of epilepsy and unprovoked seizures in Rochester, Minnesota: 1935-1984. | Q51052283 | ||
| The effects of D-23129, a new experimental anticonvulsant drug, on neurotransmitter amino acids in the rat hippocampus in vitro. | Q51589015 | ||
| Long-term prognosis in children with neonatal seizures: a population-based study. | Q51897641 | ||
| Developmental changes in KCNQ2 and KCNQ3 expression in human brain: possible contribution to the age-dependent etiology of benign familial neonatal convulsions. | Q51968139 | ||
| Developmental changes in human γ‐aminobutyric acida receptor subunit composition | Q52222249 | ||
| Postnatal development of GABA-mediated synaptic inhibition in rat hippocampus. | Q52248285 | ||
| Whole exome sequencing identifies KCNQ2 mutations in Ohtahara syndrome | Q59697636 | ||
| Incidence of Neonatal Seizures in Harris County, Texas, 1992-1994 | Q60213758 | ||
| The influence of immaturity on hypoxic‐ischemic brain damage in the rat | Q70784641 | ||
| Neonatal hypoxia and epileptic risk: a clinical prospective study | Q70790314 | ||
| Flupirtine protects neurons against excitotoxic or ischemic damage and inhibits the increase in cytosolic Ca2+ concentration | Q71377073 | ||
| A population-based study of neonatal seizures in Fayette County, Kentucky | Q72173895 | ||
| Seizures accelerate anoxia-induced neuronal death in the neonatal rat hippocampus | Q73064718 | ||
| KCNQ/M-currents contribute to the resting membrane potential in rat visceral sensory neurons | Q79733814 | ||
| Cerebral blood flow response to a hypoxic-ischemic insult differs in neonatal and juvenile rats | Q80990041 | ||
| P921 | main subject | hypoxia | Q105688 |
| neonatal hypoxic-ischemic encephalopathy | Q5832339 | ||
| P1104 | number of pages | 10 | |
| P304 | page(s) | 126-135 | |
| P577 | publication date | 2017-06-03 | |
| P1433 | published in | Neuropharmacology | Q15332439 |
| P1476 | title | Anticonvulsant effect of flupirtine in an animal model of neonatal hypoxic-ischemic encephalopathy | |
| P478 | volume | 123 |
| Q58797159 | A Model of Perinatal Ischemic Stroke in the Rat: 20 Years Already and What Lessons? |
| Q60952978 | Brain Distribution and Metabolism of Flupirtine, a Nonopioid Analgesic Drug with Antiseizure Effects, in Neonatal Rats |
| Q92376694 | Effects of a potassium channel opener on brain injury and neurologic outcomes in an animal model of neonatal hypoxic-ischemic injury |
| Q60908036 | Flupirtine Analogues: Explorative Synthesis and Influence of Chemical Structure on K7.2/K7.3 Channel Opening Activity |
| Q47149739 | Flupirtine and diazepam combination terminates established status epilepticus: results in three rodent models |
| Q90768175 | Functional responses of the hippocampus to hyperexcitability depend on directed, neuron-specific KCNQ2 K+ channel plasticity |
| Q72502645 | Neuronal Circuit Activity during Neonatal Hypoxic–Ischemic Seizures in Mice |
| Q64956040 | Sex-Dependent Signaling Pathways Underlying Seizure Susceptibility and the Role of Chloride Cotransporters. |
| Q92303655 | Sulfide Analogues of Flupirtine and Retigabine with Nanomolar KV 7.2/KV 7.3 Channel Opening Activity |
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