Modeling cocaine relapse in rodents: Behavioral considerations and circuit mechanisms.

scientific article published on 3 January 2018

Modeling cocaine relapse in rodents: Behavioral considerations and circuit mechanisms. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.PNPBP.2018.01.002
P932PMC publication ID6034989
P698PubMed publication ID29305936

P50authorStephen V. MahlerQ53481431
P2093author name stringHannah Schoch
Mitchell R Farrell
P2860cites workDamage to the insula disrupts addiction to cigarette smokingQ24605252
Linking context with reward: a functional circuit from hippocampal CA3 to ventral tegmental areaQ24623124
Stress, dysregulation of drug reward pathways, and the transition to drug dependenceQ24629577
Memory Systems and the Addicted BrainQ26768574
Neural substrates of cue reactivity: association with treatment outcomes and relapseQ26782278
Multiple roles for orexin/hypocretin in addictionQ27009536
The Dorsal Agranular Insular Cortex Regulates the Cued Reinstatement of Cocaine-Seeking, but not Food-Seeking, Behavior in RatsQ27310605
Excessive cocaine use results from decreased phasic dopamine signaling in the striatumQ27313191
Drug dependence, a chronic medical illness: implications for treatment, insurance, and outcomes evaluationQ28140216
Meta-analysis of cue-reactivity in addiction researchQ28140862
Extinction circuits for fear and addiction overlap in prefrontal cortexQ28241943
Differential effects of the novel kappa opioid receptor antagonist, JDTic, on reinstatement of cocaine-seeking induced by footshock stressors vs cocaine primes and its antidepressant-like effects in ratsQ28273954
Functional differentiation in the hippocampusQ28293360
Neuroadaptation. Incubation of cocaine craving after withdrawalQ28343773
Fos protein expression and cocaine-seeking behavior in rats after exposure to a cocaine self-administration environmentQ28368213
Limbic activation during cue-induced cocaine cravingQ28369526
A role for the bed nucleus of the stria terminalis, but not the amygdala, in the effects of corticotropin-releasing factor on stress-induced reinstatement of cocaine seekingQ28373935
Cue-Reactors: Individual Differences in Cue-Induced Craving after Food or Smoking AbstinenceQ28476066
Effects of length of abstinence on decision-making and craving in methamphetamine abusersQ28534826
The ventral pallidum: Subregion-specific functional anatomy and roles in motivated behaviors.Q28603668
A Memory Retrieval-Extinction Procedure to Prevent Drug Craving and RelapseQ28972241
The neural basis of addiction: a pathology of motivation and choiceQ29615901
The reinstatement model of drug relapse: history, methodology and major findingsQ29616241
Are the dorsal and ventral hippocampus functionally distinct structures?Q29619734
The reward circuit: linking primate anatomy and human imagingQ29619828
Stress-Induced Reinstatement of Drug Seeking: 20 Years of Progress.Q30366964
Optogenetic dissection of neural circuits underlying emotional valence and motivated behaviorsQ30434815
Serotonin 2A receptors differentially contribute to abuse-related effects of cocaine and cocaine-induced nigrostriatal and mesolimbic dopamine overflow in nonhuman primatesQ30443072
Specificity in the projection patterns of accumbal core and shell in the rat.Q30451154
Noradrenergic transmission in the extended amygdala: role in increased drug-seeking and relapse during protracted drug abstinenceQ30455336
Neurobiology of craving, conditioned reward and relapseQ36015599
Why does the rapid delivery of drugs to the brain promote addiction?Q36024367
The motivation to self-administer is increased after a history of spiking brain levels of cocaineQ36035934
Role of a Lateral Orbital Frontal Cortex-Basolateral Amygdala Circuit in Cue-Induced Cocaine-Seeking Behavior.Q36106078
Hypocretin/orexin regulation of dopamine signaling: implications for reward and reinforcement mechanismsQ36177962
Toward biomarkers of the addicted human brain: Using neuroimaging to predict relapse and sustained abstinence in substance use disorderQ36316106
Anatomy and pharmacology of cocaine priming-induced reinstatement of drug seekingQ36328136
Nicotine and nonnicotine factors in cigarette addictionQ36345893
How Preclinical Models Evolved to Resemble the Diagnostic Criteria of Drug AddictionQ36433035
A Method for Psychosocial Stress-Induced Reinstatement of Cocaine Seeking in RatsQ36445727
Contextual and temporal modulation of extinction: behavioral and biological mechanisms.Q36450189
Context-induced relapse to alcohol seeking after punishment in a rat modelQ36454445
Antagonism of GABA-B but not GABA-A receptors in the VTA prevents stress- and intra-VTA CRF-induced reinstatement of extinguished cocaine seeking in ratsQ36474838
Prefrontal mechanisms in extinction of conditioned fear.Q36483236
Hierarchical recruitment of phasic dopamine signaling in the striatum during the progression of cocaine use.Q36483638
Inhibitory control and emotional stress regulation: neuroimaging evidence for frontal-limbic dysfunction in psycho-stimulant addictionQ36489516
Harnessing reconsolidation to weaken fear and appetitive memories: A meta-analysis of post-retrieval extinction effectsQ36599325
The behavioral economics of drug self-administration: a review and new analytical approach for within-session proceduresQ36609580
Contingency management for treatment of substance use disorders: a meta-analysisQ36620696
The neural encoding of cocaine-induced devaluation in the ventral pallidumQ36763222
The selective dopamine β-hydroxylase inhibitor nepicastat attenuates multiple aspects of cocaine-seeking behaviorQ36775245
Regulation of firing of dopaminergic neurons and control of goal-directed behaviorsQ36776758
Recent developments in animal models of drug relapse.Q36817017
Norepinephrine at the nexus of arousal, motivation and relapseQ36932596
Ventral Pallidum Neurons Encode Incentive Value and Promote Cue-Elicited Instrumental ActionsQ37014182
Ventral pallidum roles in reward and motivationQ37023219
Review. Context-induced relapse to drug seeking: a reviewQ37024146
Review. Positron emission tomography imaging studies of dopamine receptors in primate models of addictionQ37024151
An orexin hotspot in ventral pallidum amplifies hedonic 'liking' for sweetnessQ37030166
Behavioral economic assessment of price and cocaine consumption following self-administration histories that produce escalation of either final ratios or intakeQ37060495
Evaluation of the "Pipeline" for Development of Medications for Cocaine Use Disorder: A Review of Translational Preclinical, Human Laboratory, and Clinical Trial ResearchQ37062538
Reinstatement in a cocaine versus food choice situation: reversal of preference between drug and non-drug rewardsQ37067288
A conflict rat model of cue-induced relapse to cocaine seekingQ37069439
Individual differences in the attribution of incentive salience to reward-related cues: Implications for addictionQ37082580
Neural Activity in the Ventral Pallidum Encodes Variation in the Incentive Value of a Reward CueQ37127862
Orexins contribute to restraint stress-induced cocaine relapse by endocannabinoid-mediated disinhibition of dopaminergic neurons.Q37128023
Optogenetic evidence that pallidal projections, not nigral projections, from the nucleus accumbens core are necessary for reinstating cocaine seekingQ37128118
The reinstatement model of drug relapse: recent neurobiological findings, emerging research topics, and translational researchQ37164797
Prelimbic to Accumbens Core Pathway Is Recruited in a Dopamine-Dependent Manner to Drive Cued Reinstatement of Cocaine SeekingQ37180972
Control of arousal by the orexin neuronsQ37198793
Reinstatement of cocaine seeking by hypocretin (orexin) in the ventral tegmental area: independence from the local corticotropin-releasing factor networkQ37250738
Cortico-limbic-striatal circuits subserving different forms of cost-benefit decision makingQ37334621
Conflation of cocaine seeking and cocaine taking responses in IV self-administration experiments in rats: methodological and interpretational considerationsQ37337379
The Neural Bases of Disgust for Cheese: An fMRI StudyQ37342474
Addiction as a pathology in prefrontal cortical regulation of corticostriatal habit circuitryQ37346465
c-Fos expression associated with reinstatement of cocaine-seeking behavior by response-contingent conditioned cuesQ37357317
Opioid modulation of ventral pallidal afferents to ventral tegmental area neuronsQ37398003
Escalation of drug self-administration as a hallmark of persistent addiction liabilityQ37400689
Orexin/hypocretin signaling at the orexin 1 receptor regulates cue-elicited cocaine-seekingQ37407124
Optogenetic dissection of basolateral amygdala projections during cue-induced reinstatement of cocaine seekingQ37412121
Fos expression induced by cocaine-conditioned cues in male and female ratsQ37424530
Orexin/hypocretin is necessary for context-driven cocaine-seekingQ37439538
Carrots and sticks fail to change behavior in cocaine addictionQ37485715
Contribution of a mesocorticolimbic subcircuit to drug context-induced reinstatement of cocaine-seeking behavior in ratsQ37491577
Incubation of Cue-Induced Craving in Adults Addicted to Cocaine Measured by Electroencephalography.Q37550680
Role of CRF and other neuropeptides in stress-induced reinstatement of drug seekingQ37561918
Hypocretin/orexin in arousal and stressQ37596060
Role of Dorsomedial Striatum Neuronal Ensembles in Incubation of Methamphetamine Craving after Voluntary Abstinence.Q37630520
Relapse to drug seeking following prolonged abstinence: the role of environmental stimuliQ37657129
Designer receptors show role for ventral pallidum input to ventral tegmental area in cocaine seekingQ37680125
Disruption of model-based behavior and learning by cocaine self-administration in ratsQ37696482
Hypocretin (orexin) facilitates reward by attenuating the antireward effects of its cotransmitter dynorphin in ventral tegmental area.Q37725194
Validation crisis in animal models of drug addiction: beyond non-disordered drug use toward drug addiction.Q37736785
Treatment of addiction and anxiety using extinction approaches: neural mechanisms and their treatment implications.Q37781128
Risk assessment as an evolved threat detection and analysis processQ37807747
Extinction of drug seekingQ37809133
Prefrontal cortical regulation of drug seeking in animal models of drug relapseQ37821388
Conditioned stress prevents cue-primed cocaine reinstatement only in stress-responsive ratsQ47430640
Incubation of alcohol craving during abstinence in patients with alcohol dependenceQ47783054
Conditioned increases in anxiogenic-like behavior following exposure to contextual stimuli associated with cocaine are mediated by corticotropin-releasing factorQ47794223
Effects of the 5-HT2C receptor agonist CP809101 in the amygdala on reinstatement of cocaine-seeking behavior and anxiety-like behaviorQ47849383
The role of corticotropin-releasing factor and corticosterone in stress- and cocaine-induced relapse to cocaine seeking in rats.Q47892402
Neural mechanisms of extinguishing drug and pleasant cue associations in human addiction: role of the VMPFC.Q48033920
Interactions of the basolateral amygdala with the dorsal hippocampus and dorsomedial prefrontal cortex regulate drug context-induced reinstatement of cocaine-seeking in ratsQ48097153
Molecular and synaptic mechanisms regulating drug-associated memories: Towards a bidirectional treatment strategy.Q48110676
Behavioral and neural mechanisms underlying habitual and compulsive drug seekingQ48121261
Disgust sensitivity predicts the insula and pallidal response to pictures of disgusting foods.Q48145065
Dorsal Hippocampus Drives Context-Induced Cocaine Seeking via Inputs to Lateral Septum.Q48201605
Context-induced relapse to cocaine seeking after punishment-imposed abstinence is associated with activation of cortical and subcortical brain regions.Q48203236
The neural correlates and role of D1 dopamine receptors in renewal of extinguished alcohol-seeking.Q48242786
Individual differences in rhesus monkeys' demand for drugs of abuseQ48247372
Ventral pallidal projections to mediodorsal thalamus and ventral tegmental area play distinct roles in outcome-specific Pavlovian-instrumental transfer.Q48262090
Orexin-1 receptor signalling within the ventral tegmental area, but not the paraventricular thalamus, is critical to regulating cue-induced reinstatement of cocaine-seeking.Q48275805
CP-154,526, a CRF type-1 receptor antagonist, attenuates the cue-and methamphetamine-induced reinstatement of extinguished methamphetamine-seeking behavior in ratsQ48362344
Conditioned release of corticosterone by contextual stimuli associated with cocaine is mediated by corticotropin-releasing factorQ48445424
Central injections of CRF reinstate cocaine seeking in rats after postinjection delays of up to 3 h: an influence of time and environmental contextQ48500729
Conditioning factors in drug abuse: can they explain compulsion?Q48722496
Orexin (hypocretin) neurons contain dynorphin.Q48785521
Two transpallidal pathways originating in the rat nucleus accumbensQ48835505
Exacerbated Craving in the Presence of Stress and Drug Cues in Drug-Dependent PatientsQ50143465
Gender differences in the relapse experiences of cocaine patients.Q50992697
Psychological stress, drug-related cues and cocaine craving.Q51074066
Conditioned responses to cocaine-related stimuli in cocaine abuse patients.Q51153833
Alternative reinforcers differentially modify cocaine self-administration by humans.Q51400652
Vertical shifts in self-administration dose-response functions predict a drug-vulnerable phenotype predisposed to addiction.Q51401027
Abstinence symptomatology and psychiatric diagnosis in cocaine abusers. Clinical observations.Q51813794
Where does damage lead to enhanced food aversion: the ventral pallidum/substantia innominata or lateral hypothalamus?Q52222348
Progressive ratio as a measure of reward strength.Q52357905
Stress-induced relapse to heroin and cocaine seeking in rats: a reviewQ74248968
Optogenetic activation of GABAergic neurons in the nucleus accumbens decreases the activity of the ventral pallidum and the expression of cocaine-context-associated memoryQ42452997
Time-dependent changes in cocaine-seeking behavior and extracellular dopamine levels in the amygdala during cocaine withdrawal.Q42456000
Transition from moderate to excessive drug intake: change in hedonic set point.Q42539135
Stress-induced relapse to drug seeking in the rat: role of the bed nucleus of the stria terminalis and amygdalaQ42720381
Alpha-2 adrenergic receptor agonists block stress-induced reinstatement of cocaine seekingQ43504794
Dopamine, but not glutamate, receptor blockade in the basolateral amygdala attenuates conditioned reward in a rat model of relapse to cocaine-seeking behaviorQ43606990
Conditioned reinstatement of drug-seeking behavior with a discrete compound stimulus classically conditioned with intravenous cocaineQ43755263
The circuitry mediating cocaine-induced reinstatement of drug-seeking behavior.Q43770574
Neural systems and cue-induced cocaine cravingQ43890442
Blockade of stress-induced but not cocaine-induced reinstatement by infusion of noradrenergic antagonists into the bed nucleus of the stria terminalis or the central nucleus of the amygdala.Q44050094
Effects of SCH 23390 and eticlopride on cocaine-seeking produced by cocaine and WIN 35,428 in ratsQ44208074
A role for the prefrontal cortex in stress- and cocaine-induced reinstatement of cocaine seeking in ratsQ44222954
Effect of dopamine receptor antagonists on renewal of cocaine seeking by reexposure to drug-associated contextual cuesQ44237566
Administration of the D1-like dopamine receptor antagonist SCH-23390 into the medial nucleus accumbens shell attenuates cocaine priming-induced reinstatement of drug-seeking behavior in ratsQ44255256
Excitation of ventral tegmental area dopaminergic and nondopaminergic neurons by orexins/hypocretins.Q44270164
D1-receptor drugs and cocaine-seeking behavior: investigation of receptor mediation and behavioral disruption in ratsQ44273583
Opioid limbic circuit for reward: interaction between hedonic hotspots of nucleus accumbens and ventral pallidum.Q44333851
κ-Opioid Agonists Directly Inhibit Midbrain Dopaminergic NeuronsQ44343360
Afferent modulation of dopamine neuron firing differentially regulates tonic and phasic dopamine transmissionQ44536213
Differential roles of 5-HT receptor subtypes in cue and cocaine reinstatement of cocaine-seeking behavior in ratsQ44662298
Assessing the initiation of cocaine self-administration in humans during abstinence: effects of dose, alternative reinforcement, and primingQ44675322
Limbic and motor circuitry underlying footshock-induced reinstatement of cocaine-seeking behavior.Q44770090
Cocaine seeking over extended withdrawal periods in rats: different time courses of responding induced by cocaine cues versus cocaine priming over the first 6 monthsQ44835552
Individual differences in sensitivity to factors provoking reinstatement of cocaine-seeking behavior.Q44890749
The role of prefrontal cortex D1-like and D2-like receptors in cocaine-seeking behavior in ratsQ45017073
Evidence for addiction-like behavior in the rat.Q45018179
Drug seeking becomes compulsive after prolonged cocaine self-administration.Q45018183
The role of the dorsomedial prefrontal cortex, basolateral amygdala, and dorsal hippocampus in contextual reinstatement of cocaine seeking in ratsQ45106402
Rapid dopamine signaling in the nucleus accumbens during contingent and noncontingent cocaine administrationQ45153783
A paradigm to investigate the self-regulation of cocaine administration in humansQ45279117
A choice-based screening method for compulsive drug users in rats.Q45334023
High impulsivity predicts relapse to cocaine-seeking after punishment-induced abstinenceQ46139709
Interaction between noradrenaline and corticotrophin-releasing factor in the reinstatement of cocaine seeking in the rat.Q46263923
Molecular substrates for retrieval and reconsolidation of cocaine-associated contextual memoryQ46269232
Effects of haloperidol on reactions to smoking cues in humans.Q46379112
Pattern of intake and drug craving predict the development of cocaine addiction-like behavior in rats.Q46474451
A Decade of Orexin/Hypocretin and Addiction: Where Are We Now?Q46514264
Afferents of the ventral tegmental area in the rat-anatomical substratum for integrative functionsQ46636697
A role for lateral hypothalamic orexin neurons in reward seekingQ46650606
Disrupting reconsolidation of drug memories reduces cocaine-seeking behavior.Q46698686
Effects of intra-nucleus accumbens shell administration of dopamine agonists and antagonists on cocaine-taking and cocaine-seeking behaviors in the rat.Q46703907
The ventral pallidum and hedonic reward: neurochemical maps of sucrose "liking" and food intake.Q46715127
Administration of the D2 dopamine receptor antagonist sulpiride into the shell, but not the core, of the nucleus accumbens attenuates cocaine priming-induced reinstatement of drug seekingQ46736579
Stimulation of D1-like or D2 dopamine receptors in the shell, but not the core, of the nucleus accumbens reinstates cocaine-seeking behaviour in the rat.Q46899471
High and escalating levels of cocaine intake are dissociable from subsequent incentive motivation for the drug in ratsQ47310565
Dynorphin Counteracts Orexin in the Paraventricular Nucleus of the Thalamus: Cellular and Behavioral EvidenceQ47312810
Intermittent intake of rapid cocaine injections promotes robust psychomotor sensitization, increased incentive motivation for the drug and mGlu2/3 receptor dysregulationQ47368252
Incubation of Methamphetamine but not Heroin Craving After Voluntary Abstinence in Male and Female RatsQ47375023
Ventral Pallidum Output Pathways in Context-Induced Reinstatement of Alcohol Seeking.Q47383844
Convergence of Reinforcing and Anhedonic Cocaine Effects in the Ventral Pallidum.Q47385037
α(2) Adrenergic and imidazoline receptor agonists prevent cue-induced cocaine seekingQ30462473
Pathways to relapse: the neurobiology of drug- and stress-induced relapse to drug-takingQ30501299
Maturation of silent synapses in amygdala-accumbens projection contributes to incubation of cocaine cravingQ30556607
Subregion-specific role of glutamate receptors in the nucleus accumbens on drug context-induced reinstatement of cocaine-seeking behavior in ratsQ30635363
Chemogenetic manipulation of ventral pallidal neurons impairs acquisition of sign-tracking in ratsQ30699188
Ventral tegmental area glutamate neurons co-release GABA and promote positive reinforcement.Q30832524
Cocaine-seeking by rats: regulation, reinforcement and activationQ31515869
Imaging stress- and cue-induced drug and alcohol craving: association with relapse and clinical implicationsQ33278978
A ventral tegmental CRF-glutamate-dopamine interaction in addictionQ33643410
Regulation of cocaine self-administration in humans: lack of evidence for loading and maintenance phasesQ33665721
A critical role of lateral hypothalamus in context-induced relapse to alcohol seeking after punishment-imposed abstinence.Q33671645
The concepts of the ventral striatopallidal system and extended amygdalaQ33692710
Pharmacological and environmental determinants of relapse to cocaine-seeking behaviorQ33748935
Incubation of methamphetamine and palatable food craving after punishment-induced abstinenceQ33764326
The infralimbic cortex regulates the consolidation of extinction after cocaine self-administrationQ33781321
Regulation of cocaine-reinstated drug-seeking behavior by kappa-opioid receptors in the ventral tegmental area of ratsQ33835206
The hypocretin-orexin system regulates cocaine self-administration via actions on the mesolimbic dopamine systemQ33897435
CRF-R2 and the heterosynaptic regulation of VTA glutamate during reinstatement of cocaine seekingQ33969858
Economic demand predicts addiction-like behavior and therapeutic efficacy of oxytocin in the rat.Q34060612
A role for the CRF-containing pathway from central nucleus of the amygdala to bed nucleus of the stria terminalis in the stress-induced reinstatement of cocaine seeking in ratsQ34109948
Stress-induced cocaine seeking requires a beta-2 adrenergic receptor-regulated pathway from the ventral bed nucleus of the stria terminalis that regulates CRF actions in the ventral tegmental area.Q34162794
Role for hypocretin in mediating stress-induced reinstatement of cocaine-seeking behaviorQ34245006
The persistence of maladaptive memory: addiction, drug memories and anti-relapse treatmentsQ34250281
Reinstatement of cocaine-reinforced responding in the rat.Q34269959
Learning to forget: manipulating extinction and reconsolidation processes to treat addictionQ34277629
Effect of early and later colony housing on oral ingestion of morphine in ratsQ34283840
Prominent activation of brainstem and pallidal afferents of the ventral tegmental area by cocaineQ34297880
Yohimbine administration and cue-reactivity in cocaine-dependent individualsQ34308172
Pharmacologically-induced stress: a cross-species probe for translational research in drug addiction and relapseQ34310263
Sub-region specific contribution of the ventral hippocampus to drug context-induced reinstatement of cocaine-seeking behavior in ratsQ34328884
Optogenetic inhibition of cocaine seeking in ratsQ34347910
Opposite modulation of cocaine-seeking behavior by D1- and D2-like dopamine receptor agonistsQ34374970
Cocaine experience establishes control of midbrain glutamate and dopamine by corticotropin-releasing factor: a role in stress-induced relapse to drug seeking.Q34423187
Knockdown of CRF1 receptors in the ventral tegmental area attenuates cue- and acute food deprivation stress-induced cocaine seeking in mice.Q34435527
Interaction of the basolateral amygdala and orbitofrontal cortex is critical for drug context-induced reinstatement of cocaine-seeking behavior in ratsQ34490250
Orexin A in the VTA is critical for the induction of synaptic plasticity and behavioral sensitization to cocaine.Q34494218
Incubation of cue-induced cigarette craving during abstinence in human smokersQ34524958
Applying extinction research and theory to cue-exposure addiction treatmentsQ34541677
Neurobiology of relapse to heroin and cocaine seeking: a reviewQ34547387
Poststress block of kappa opioid receptors rescues long-term potentiation of inhibitory synapses and prevents reinstatement of cocaine seeking.Q34557997
High-novelty-preference rats are predisposed to compulsive cocaine self-administrationQ34661828
Ramifications of the globus pallidus in the rat as indicated by patterns of immunohistochemistryQ34707716
Self-administration of drugs in animals and humans as a model and an investigative toolQ34716722
Stimulation of dopamine D2/D3 but not D1 receptors in the central amygdala decreases cocaine-seeking behaviorQ34768667
Illuminating circuitry relevant to psychiatric disorders with optogeneticsQ34943448
Effect of yohimbine on reinstatement of operant responding in rats is dependent on cue contingency but not food reward historyQ35020124
Cognitive enhancers for facilitating drug cue extinction: insights from animal modelsQ35043180
Dopamine and effort-based decision makingQ35064882
Brain circuitry and the reinstatement of cocaine-seeking behaviorQ35090481
Toward a model of drug relapse: an assessment of the validity of the reinstatement procedureQ35103785
Motivational activation: a unifying hypothesis of orexin/hypocretin functionQ35105241
Drug Addiction, Relapse, and the AmygdalaQ35118434
Different neural substrates mediate cocaine seeking after abstinence versus extinction training: a critical role for the dorsolateral caudate-putamenQ35141659
Differentiating the rapid actions of cocaineQ35161471
Role of corticostriatal circuits in context-induced reinstatement of drug seekingQ35185615
Effects of mGluR1 antagonism in the dorsal hippocampus on drug context-induced reinstatement of cocaine-seeking behavior in ratsQ35239835
Translational and reverse translational research on the role of stress in drug craving and relapseQ35332832
New medications for drug addiction hiding in glutamatergic neuroplasticityQ35333393
Glutamatergic afferents of the ventral tegmental area in the rat.Q35460754
Interaction between the basolateral amygdala and dorsal hippocampus is critical for cocaine memory reconsolidation and subsequent drug context-induced cocaine-seeking behavior in ratsQ35513933
Cue-induced reinstatement of cocaine seeking in the rat "conflict model": effect of prolonged home-cage confinementQ35678062
Control of cocaine-seeking behavior by drug-associated stimuli in rats: effects on recovery of extinguished operant-responding and extracellular dopamine levels in amygdala and nucleus accumbensQ35682043
Satiating effects of cocaine are controlled by dopamine actions in the nucleus accumbens coreQ35689736
Orexin-1 receptor mediation of cocaine seeking in male and female ratsQ35776806
A novel IV cocaine self-administration procedure in rats: differential effects of dopamine, serotonin, and GABA drug pre-treatments on cocaine consumption and maximal price paidQ35789196
Selective inactivation of the ventral hippocampus attenuates cue-induced and cocaine-primed reinstatement of drug-seeking in ratsQ35850576
Effect of the Novel Positive Allosteric Modulator of Metabotropic Glutamate Receptor 2 AZD8529 on Incubation of Methamphetamine Craving After Prolonged Voluntary Abstinence in a Rat Model.Q35988776
Coding the direct/indirect pathways by D1 and D2 receptors is not valid for accumbens projectionsQ36001660
The behavioral economics of drug dependence: towards the consilience of economics and behavioral neuroscienceQ37821398
Stress-induced modulation of instrumental behavior: from goal-directed to habitual control of actionQ37827210
A cognitive model of drug urges and drug-use behavior: role of automatic and nonautomatic processesQ37921802
The science of making drug-addicted animals.Q37921873
Optogenetic investigation of neural circuits underlying brain disease in animal models.Q37994954
Optogenetic strategies to dissect the neural circuits that underlie reward and addictionQ38050149
Neurobiology of addiction versus drug use driven by lack of choiceQ38083389
Optogenetic insights into striatal function and behaviorQ38102812
Extinction of drug seeking: Neural circuits and approaches to augmentationQ38115079
Neurobiological mechanisms underlying relapse to cocaine use: contributions of CRF and noradrenergic systems and regulation by glucocorticoidsQ38170425
Neural and psychological mechanisms underlying compulsive drug seeking habits and drug memories--indications for novel treatments of addictionQ38220754
Emerging drugs for the treatment of cocaine use disorder: a review of neurobiological targets and pharmacotherapyQ38271498
Rescuing cocaine-induced prefrontal cortex hypoactivity prevents compulsive cocaine seeking.Q38421614
In search of predictive endophenotypes in addiction: insights from preclinical researchQ38611507
Animal models of drug relapse and craving: From drug priming-induced reinstatement to incubation of craving after voluntary abstinenceQ38715348
Norepinephrine regulates cocaine-primed reinstatement via α1-adrenergic receptors in the medial prefrontal cortexQ38845514
How contexts promote and prevent relapse to drug seeking.Q38950401
Hypocretin/Orexin and Plastic Adaptations Associated with Drug AbuseQ39183160
Hypocretin Neurotransmission Within the Central Amygdala Mediates Escalated Cocaine Self-administration and Stress-Induced Reinstatement in RatsQ39447778
Kappa opioid receptors regulate stress-induced cocaine seeking and synaptic plasticityQ39992483
Distinct Ventral Pallidal Neural Populations Mediate Separate Symptoms of Depression.Q40130435
Potentiation of cue-induced reinstatement of cocaine-seeking in rats by the anxiogenic drug yohimbineQ40296005
Interactions between VTA orexin and glutamate in cue-induced reinstatement of cocaine seeking in rats.Q40557626
Behavioral economics of drug self-administration: an introductionQ40791207
The economic context of drug and non-drug reinforcers affects acquisition and maintenance of drug-reinforced behavior and withdrawal effectsQ40791219
Selective Enhancement of Dopamine Release in the Ventral Pallidum of Methamphetamine-Sensitized MiceQ41524173
The Influence of Alternative Reinforcers on Cocaine Use and Abuse: A Brief ReviewQ41527769
Less is more: prolonged intermittent access cocaine self-administration produces incentive-sensitization and addiction-like behaviorQ41656843
Bidirectional modulation of incubation of cocaine craving by silent synapse-based remodeling of prefrontal cortex to accumbens projectionsQ41908316
Fos activation of selective afferents to ventral tegmental area during cue-induced reinstatement of cocaine seeking in ratsQ42039995
Balancing risk and reward: a rat model of risky decision makingQ42249282
Reduced forebrain serotonin transmission is causally involved in the development of compulsive cocaine seeking in ratsQ42325301
A role for the ventral pallidum in context-induced and primed reinstatement of alcohol seeking.Q42440091
P433issuePt A
P304page(s)33-47
P577publication date2018-01-03
P1433published inProgress in Neuro-Psychopharmacology & Biological PsychiatryQ15616665
P1476titleModeling cocaine relapse in rodents: Behavioral considerations and circuit mechanisms
P478volume87

Reverse relations

cites work (P2860)
Q93183273Chemogenetic Manipulations of Ventral Tegmental Area Dopamine Neurons Reveal Multifaceted Roles in Cocaine Abuse
Q91747948Common neurocircuitry mediating drug and fear relapse in preclinical models
Q92439407Contribution of D1R-expressing neurons of the dorsal dentate gyrus and Cav1.2 channels in extinction of cocaine conditioned place preference
Q90744653Dopamine receptor antagonists effects on low-dimensional attractors of local field potentials in optogenetic mice
Q89236068Overexpression of neuronal RNA-binding protein HuD increases reward induced reinstatement of an instrumental response
Q88612671Persistent effects of obesity: a neuroplasticity hypothesis
Q64244312Role of venlafaxine in relapse to methamphetamine seeking. Potential treatment option for drug dependence
Q52689998Ventral pallidal encoding of reward-seeking behavior depends on the underlying associative structure.
Q93058461Ventral pallidum is essential for cocaine relapse after voluntary abstinence in rats
Q64949941What does the Fos say? Using Fos-based approaches to understand the contribution of stress to substance use disorders.

Search more.