| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/J.XPHS.2017.08.011 |
| P8608 | Fatcat ID | release_mumihkgbevfyfezyp7at24s36e |
| P932 | PMC publication ID | 6178931 |
| P698 | PubMed publication ID | 28843351 |
| P50 | author | Krishna M G Mallela | Q81162830 |
| Surinder P Singh | Q96189566 | ||
| P2093 | author name string | David N M Jones | |
| Swati Bandi | |||
| P2860 | cites work | Effects of Tween 20 and Tween 80 on the stability of Albutropin during agitation | Q28247401 |
| The Surface Activity of Proteins | Q30052500 | ||
| Technical decision-making with higher order structure data: specific binding of a nonionic detergent perturbs higher order structure of a therapeutic monoclonal antibody. | Q30370227 | ||
| Infrared Spectroscopic Studies of Lyophilization‐ and Temperature‐Induced Protein Aggregation | Q30417494 | ||
| Protein structural changes induced by their uptake at interfaces | Q30692647 | ||
| Global analysis of three-state protein unfolding data | Q30947045 | ||
| Isothermal titration calorimetry: experimental design, data analysis, and probing macromolecule/ligand binding and kinetic interactions | Q31134461 | ||
| Anatomy of the antibody molecule | Q34060425 | ||
| Role of benzyl alcohol in the unfolding and aggregation of interferon α-2a. | Q35032786 | ||
| Physical stability of proteins in aqueous solution: mechanism and driving forces in nonnative protein aggregation | Q35563682 | ||
| Backbone (1)H, (13)C, and (15)N resonance assignments of the Fc fragment of human immunoglobulin G glycoprotein | Q36054689 | ||
| Two-state vs. multistate protein unfolding studied by optical melting and hydrogen exchange | Q36281744 | ||
| Antibody structure, instability, and formulation | Q36602885 | ||
| Protein aggregation and bioprocessing | Q36616347 | ||
| Raman spectroscopy of protein pharmaceuticals | Q36936948 | ||
| Tween protects recombinant human growth hormone against agitation-induced damage via hydrophobic interactions | Q77214878 | ||
| Effect of Tween 20 on freeze-thawing- and agitation-induced aggregation of recombinant human factor XIII | Q77214915 | ||
| Investigation of protein-surfactant interactions by analytical ultracentrifugation and electron paramagnetic resonance: the use of recombinant human tissue factor as an example | Q77974386 | ||
| Dual effects of Tween 80 on protein stability | Q80782787 | ||
| Development of high concentration protein biopharmaceuticals: the use of platform approaches in formulation development | Q83618897 | ||
| Surface activity of a monoclonal antibody | Q84350038 | ||
| Formulation Development of Therapeutic Monoclonal Antibodies Using High-Throughput Fluorescence and Static Light Scattering Techniques: Role of Conformational and Colloidal Stability | Q85226583 | ||
| Gelation of a monoclonal antibody at the silicone oil-water interface and subsequent rupture of the interfacial gel results in aggregation and particle formation | Q86634452 | ||
| Partial unfolding of a monoclonal antibody: role of a single domain in driving protein aggregation | Q87827567 | ||
| Polysorbates 20 and 80 used in the formulation of protein biotherapeutics: structure and degradation pathways | Q36987089 | ||
| Biosimilar structural comparability assessment by NMR: from small proteins to monoclonal antibodies | Q37220066 | ||
| A comparison of biophysical characterization techniques in predicting monoclonal antibody stability | Q37287010 | ||
| Irreversible inactivation of interleukin 2 in a pump-based delivery environment | Q37589083 | ||
| Effect of antimicrobial preservatives on partial protein unfolding and aggregation | Q37708774 | ||
| The therapeutic monoclonal antibody market | Q38296275 | ||
| Effects of Tween 80 and sucrose on acute short-term stability and long-term storage at -20 degrees C of a recombinant hemoglobin | Q38333776 | ||
| Investigation on fouling mechanisms for recombinant human growth hormone sterile filtration | Q38554635 | ||
| Protein denaturation by combined effect of shear and air-liquid interface | Q38554752 | ||
| Mechanisms of m-cresol-induced protein aggregation studied using a model protein cytochrome c. | Q39164829 | ||
| Trends on Analytical Characterization of Polysorbates and Their Degradation Products in Biopharmaceutical Formulations | Q39182721 | ||
| Effects of Protein Conformation, Apparent Solubility, and Protein-Protein Interactions on the Rates and Mechanisms of Aggregation for an IgG1Monoclonal Antibody | Q39630102 | ||
| The effects of excipients on protein aggregation during agitation: an interfacial shear rheology study | Q41907182 | ||
| Correlations between changes in conformational dynamics and physical stability in a mutant IgG1 mAb engineered for extended serum half-life | Q42107564 | ||
| Silicone oil- and agitation-induced aggregation of a monoclonal antibody in aqueous solution | Q42108007 | ||
| A new mechanism for decreasing aggregation of recombinant human interferon-gamma by a surfactant: slowed dissolution of lyophilized formulations in a solution containing 0.03% polysorbate 20. | Q42163409 | ||
| Role of partial protein unfolding in alcohol-induced protein aggregation | Q42496692 | ||
| Effect of polysorbate 80 concentration on thermal and photostability of a monoclonal antibody | Q43240322 | ||
| Protein adsorption and excipient effects on kinetic stability of silicone oil emulsions | Q43247305 | ||
| Effect of freezing on aggregation of human growth hormone | Q43954952 | ||
| Applications of circular dichroism (CD) for structural analysis of proteins: qualification of near- and far-UV CD for protein higher order structural analysis | Q44099920 | ||
| Surface denaturation and amyloid fibril formation of insulin at model lipid-water interfaces | Q44261780 | ||
| Loss of factor VIII activity during storage in PVC containers due to adsorption. | Q45867033 | ||
| Inverse relationship of protein concentration and aggregation. | Q46007242 | ||
| Physical and biophysical effects of polysorbate 20 and 80 on darbepoetin alfa. | Q46039740 | ||
| Quantitative spectral comparison by weighted spectral difference for protein higher order structure confirmation | Q46346139 | ||
| Protein effects on surfactant adsorption suggest the dominant mode of surfactant-mediated stabilization of protein | Q46348044 | ||
| 2D (1)H(N), (15)N Correlated NMR Methods at Natural Abundance for Obtaining Structural Maps and Statistical Comparability of Monoclonal Antibodies | Q46656897 | ||
| Structural characterization of an equilibrium unfolding intermediate in cytochrome c. | Q46940734 | ||
| Adsorption and function of recombinant Factor VIII at the air-water interface in the presence of Tween 80. | Q47355398 | ||
| A thermodynamic analysis of the binding interaction between polysorbate 20 and 80 with human serum albumins and immunoglobulins: a contribution to understand colloidal protein stabilisation | Q47846685 | ||
| Adsorption and function of recombinant factor VIII at solid-water interfaces in the presence of Tween-80. | Q47847496 | ||
| Isomerization and Oxidation in the Complementarity-Determining Regions of a Monoclonal Antibody: A Study of the Modification-Structure-Function Correlations by Hydrogen-Deuterium Exchange Mass Spectrometry. | Q51739313 | ||
| Mapping monoclonal antibody structure by 2D 13C NMR at natural abundance. | Q51744309 | ||
| Insights into protein-polysorbate interactions analysed by means of isothermal titration and differential scanning calorimetry. | Q51843226 | ||
| Excipients and their use in injectable products. | Q52193709 | ||
| Contribution of variable domains to the stability of humanized IgG1 monoclonal antibodies. | Q52581515 | ||
| Determination of CMC of polysorbate 20 in aqueous solution by surface tension method. | Q52971833 | ||
| Direct NMR evidence for an intermediate preceding the rate-limiting step in the unfolding of ribonuclease A | Q60091267 | ||
| Influence of viscosity and solubilization on dissolution rate | Q70450399 | ||
| Effect of surfactants on the physical stability of recombinant human growth hormone | Q71750056 | ||
| Surface-induced denaturation of proteins during freezing and its inhibition by surfactants | Q71876967 | ||
| Molten globule intermediate of recombinant human growth hormone: stabilization with surfactants | Q71944014 | ||
| Stability of protein formulations: investigation of surfactant effects by a novel EPR spectroscopic technique | Q72175754 | ||
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 3486-3498 | |
| P577 | publication date | 2017-08-23 | |
| P1433 | published in | Journal of Pharmaceutical Sciences | Q3186933 |
| P1476 | title | Effect of Polysorbate 20 and Polysorbate 80 on the Higher-Order Structure of a Monoclonal Antibody and Its Fab and Fc Fragments Probed Using 2D Nuclear Magnetic Resonance Spectroscopy | |
| P478 | volume | 106 |
| Q91693962 | An Evaluation of the Potential of NMR Spectroscopy and Computational Modelling Methods to Inform Biopharmaceutical Formulations |
| Q94678395 | Assessment of the Higher-Order Structure of Formulated Monoclonal Antibody Therapeutics by 2D Methyl Correlated NMR and Principal Component Analysis |
| Q91410173 | Comparison of Polysorbate 80 Hydrolysis and Oxidation on the Aggregation of a Monoclonal Antibody |
| Q57465381 | Effect of Chemical Oxidation on the Higher Order Structure, Stability, Aggregation, and Biological Function of Interferon Alpha-2a: Role of Local Structural Changes Detected by 2D NMR |
| Q61814353 | Enabling adoption of 2D-NMR for the higher order structure assessment of monoclonal antibody therapeutics |
| Q52680300 | Formulation Stabilization and Disaggregation of Bevacizumab, Ranibizumab and Aflibercept in Dilute Solutions. |
| Q98658070 | High Performance Size Exclusion Chromatography and High-Throughput Dynamic Light Scattering as orthogonal methods to screen for aggregation and stability of monoclonal antibody drug products |
| Q100311645 | Impact of polysorbate 80 grade on the interfacial properties and interfacial stress induced subvisible particle formation in monoclonal antibodies |
| Q47943464 | Multivariate Analysis of Two-Dimensional 1H, 13C Methyl NMR Spectra of Monoclonal Antibody Therapeutics To Facilitate Assessment of Higher Order Structure. |
| Q92984377 | Physicochemical Stability of Monoclonal Antibodies: A Review |
| Q101131574 | Room temperature intrinsic emission ratio of BSA correlates with percent aggregates during long-term storage |
| Q92632344 | The impact of standard accelerated stability conditions on antibody higher order structure as assessed by mass spectrometry |
| Q90718317 | What Makes Polysorbate Functional? Impact of Polysorbate 80 Grade and Quality on IgG Stability During Mechanical Stress |
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