| P50 | author | Wim Jiskoot | Q67247173 |
| P2093 | author name string | Tim Menzen | |
| | Klaus Wuchner | |
| | Andrea Hawe | |
| | Wendelin Kranz | |
| | Adam Dariusz Grabarek | |
| | Jannik Rousel | |
| | Ula Bozic | |
| P2860 | cites work | Tween protects recombinant human growth hormone against agitation-induced damage via hydrophobic interactions | Q77214878 |
| | Shaken, not stirred: mechanical stress testing of an IgG1 antibody | Q80607521 |
| | The degradation of polysorbates 20 and 80 and its potential impact on the stability of biotherapeutics | Q83519775 |
| | Analysis of polysorbate 80 and its related compounds by RP-HPLC with ELSD and MS detection | Q84030513 |
| | Meeting report on protein particles and immunogenicity of therapeutic proteins: filling in the gaps in risk evaluation and mitigation | Q84721767 |
| | The role of polysorbate 80 and HPβCD at the air-water interface of IgG solutions | Q84840874 |
| | Degradation of Polysorbates 20 and 80: Studies on Thermal Autoxidation and Hydrolysis | Q84965958 |
| | Free fatty acid particles in protein formulations, part 2: contribution of polysorbate raw material | Q85266301 |
| | Competitive adsorption of monoclonal antibodies and nonionic surfactants at solid hydrophobic surfaces | Q86103734 |
| | Gelation of a monoclonal antibody at the silicone oil-water interface and subsequent rupture of the interfacial gel results in aggregation and particle formation | Q86634452 |
| | Effect of Surfactants on Mechanical, Thermal, and Photostability of a Monoclonal Antibody | Q88668609 |
| | Considerations for the Use of Polysorbates in Biopharmaceuticals | Q88802216 |
| | Factors Influencing Polysorbate's Sensitivity Against Enzymatic Hydrolysis and Oxidative Degradation | Q91031529 |
| | Do not drop: mechanical shock in vials causes cavitation, protein aggregation, and particle formation | Q27333791 |
| | Effects of Tween 20 and Tween 80 on the stability of Albutropin during agitation | Q28247401 |
| | Response of a concentrated monoclonal antibody formulation to high shear | Q30480156 |
| | Classification and characterization of therapeutic antibody aggregates | Q30502491 |
| | Roles of conformational stability and colloidal stability in the aggregation of recombinant human granulocyte colony‐stimulating factor | Q36571961 |
| | Protein aggregation: pathways, induction factors and analysis | Q37281536 |
| | Molecular origins of surfactant-mediated stabilization of protein drugs. | Q37901731 |
| | Protein denaturation by combined effect of shear and air-liquid interface | Q38554752 |
| | Key interactions of surfactants in therapeutic protein formulations: A review | Q38598945 |
| | Inducing protein aggregation by extensional flow | Q38833560 |
| | Trends on Analytical Characterization of Polysorbates and Their Degradation Products in Biopharmaceutical Formulations | Q39182721 |
| | The effects of excipients on protein aggregation during agitation: an interfacial shear rheology study | Q41907182 |
| | Adsorption behavior of a human monoclonal antibody at hydrophilic and hydrophobic surfaces | Q41931928 |
| | Silicone oil- and agitation-induced aggregation of a monoclonal antibody in aqueous solution | Q42108007 |
| | Effect of polysorbate 80 quality on photostability of a monoclonal antibody | Q42135045 |
| | Effect of polysorbate 80 concentration on thermal and photostability of a monoclonal antibody | Q43240322 |
| | Relevant shaking stress conditions for antibody preformulation development | Q43850100 |
| | Ester hydrolysis of polysorbate 80 in mAb drug product: evidence in support of the hypothesized risk after the observation of visible particulate in mAb formulations | Q44281946 |
| | Renewal of the air-water interface as a critical system parameter of protein stability: aggregation of the human growth hormone and its prevention by surface-active compounds | Q44776180 |
| | Physical and biophysical effects of polysorbate 20 and 80 on darbepoetin alfa. | Q46039740 |
| | Effect of Polysorbate 20 and Polysorbate 80 on the Higher-Order Structure of a Monoclonal Antibody and Its Fab and Fc Fragments Probed Using 2D Nuclear Magnetic Resonance Spectroscopy | Q47902036 |
| | Friability Testing as a New Stress-Stability Assay for Biopharmaceuticals | Q48028978 |
| | A platform for preparing homogeneous proteinaceous sub-visible particles with distinct morphologies. | Q51731806 |
| | Polysorbates 20 and 80 Degradation by Group XV Lysosomal Phospholipase A2 Isomer X1 in Monoclonal Antibody Formulations. | Q51738350 |
| | Insights into protein-polysorbate interactions analysed by means of isothermal titration and differential scanning calorimetry. | Q51843226 |
| | Hydrolysis of Polysorbate 20 and 80 by a Range of Carboxylester Hydrolases. | Q53136814 |
| | Impact of Cavitation, High Shear Stress and Air/Liquid Interfaces on Protein Aggregation. | Q53426266 |
| | Postproduction Handling and Administration of Protein Pharmaceuticals and Potential Instability Issues | Q56977090 |
| | Polysorbate degradation in biotherapeutic formulations: Identification and discussion of current root causes | Q57296963 |
| | Protein aggregation - Mechanisms, detection, and control | Q57785794 |
| | Factors influencing antibody stability at solid-liquid interfaces in a high shear environment | Q58338079 |
| | Interfacial Stress in the Development of Biologics: Fundamental Understanding, Current Practice, and Future Perspective | Q64116563 |
| P433 | issue | 1 | |
| P304 | page(s) | 871-880 | |
| P577 | publication date | 2019-10-12 | |
| P1433 | published in | Journal of Pharmaceutical Sciences | Q3186933 |
| P1476 | title | What Makes Polysorbate Functional? Impact of Polysorbate 80 Grade and Quality on IgG Stability During Mechanical Stress | |
| P478 | volume | 109 | |