Silencing of Kir2 channels by caveolin-1: cross-talk with cholesterol

scientific article published on 18 July 2014

Silencing of Kir2 channels by caveolin-1: cross-talk with cholesterol is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1113/JPHYSIOL.2014.273177
P932PMC publication ID4198012
P698PubMed publication ID25038242
P5875ResearchGate publication ID263969840

P2093author name stringRichard D Minshall
Zhenlong Chen
Irena Levitan
Frederick Sachs
Avia Rosenhouse-Dantsker
Yulia Epshtein
Huazhi Han
Radhakrishnan Gnanasambandam
P2860cites workInwardly rectifying potassium channels: their structure, function, and physiological rolesQ24296441
Nitrosation-dependent caveolin 1 phosphorylation, ubiquitination, and degradation and its association with idiopathic pulmonary arterial hypertensionQ24300536
Structural basis of PIP2 activation of the classical inward rectifier K+ channel Kir2.2Q24336573
MicroRNA 802 stimulates ROMK channels by suppressing caveolin-1Q24630318
International Union of Pharmacology. LIV. Nomenclature and Molecular Relationships of Inwardly Rectifying Potassium ChannelsQ24687431
Crystal Structure of the Eukaryotic Strong Inward-Rectifier K+ Channel Kir2.2 at 3.1 A ResolutionQ27646617
Crystal structure of a Kir3.1-prokaryotic Kir channel chimeraQ27647344
Caveolin-3 negatively regulates recombinant cardiac K(ATP) channelsQ28246820
Functional expression of Kir2.x in human aortic endothelial cells: the dominant role of Kir2.2Q28256776
Primary structure and functional expression of a mouse inward rectifier potassium channelQ28297815
Identification of peptide and protein ligands for the caveolin-scaffolding domain. Implications for the interaction of caveolin with caveolae-associated proteinsQ28304307
Caveolae localize protein kinase A signaling to arterial ATP-sensitive potassium channelsQ28574925
Caveolin isoforms in resident and elicited rat peritoneal macrophagesQ28580500
Interaction with caveolin-1 modulates vascular ATP-sensitive potassium (KATP) channel activityQ28582532
Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted miceQ29615180
Structure-based reassessment of the caveolin signaling model: do caveolae regulate signaling through caveolin-protein interactions?Q30524349
Enantioselective protein-sterol interactions mediate regulation of both prokaryotic and eukaryotic inward rectifier K+ channels by cholesterol.Q33894863
The Caveolin genes: from cell biology to medicineQ33985764
Modulation of endothelial inward-rectifier K+ current by optical isomers of cholesterolQ34179380
Cholesterol sensitivity and lipid raft targeting of Kir2.1 channelsQ34188073
Maximum likelihood estimation of ion channel kinetics from macroscopic currentsQ34189697
Evaluating caveolin interactions: do proteins interact with the caveolin scaffolding domain through a widespread aromatic residue-rich motif?Q34427576
Cholesterol sensitivity of KIR2.1 is controlled by a belt of residues around the cytosolic poreQ34494367
Merging functional studies with structures of inward-rectifier K+ channelsQ35584086
Role of caveolin-1 in endothelial BKCa channel regulation of vasoreactivityQ35601325
Nitric oxide-dependent Src activation and resultant caveolin-1 phosphorylation promote eNOS/caveolin-1 binding and eNOS inhibition.Q35861809
Anthrax lethal factor activates K(+) channels to induce IL-1β secretion in macrophagesQ36642550
Lipopolysaccharide-dependent interaction between PU.1 and c-Jun determines production of lipocalin-type prostaglandin D synthase and prostaglandin D2 in macrophagesQ37190211
Identification of a C-terminus domain critical for the sensitivity of Kir2.1 to cholesterolQ37194773
Identification of novel cholesterol-binding regions in Kir2 channelsQ37312194
Direct regulation of prokaryotic Kir channel by cholesterolQ37431875
Cholesterol and ion channelsQ37705156
Comparative analysis of cholesterol sensitivity of Kir channels: role of the CD loopQ41790734
Cholesterol regulates prokaryotic Kir channel by direct binding to channel proteinQ42233169
Structural characterization of the caveolin scaffolding domain in association with cholesterol-rich membranes.Q42621806
Evidence for a gamma-interferon receptor that regulates macrophage tumoricidal activityQ42937062
Caveolae targeting and regulation of large conductance Ca(2+)-activated K+ channels in vascular endothelial cells.Q45234635
Cytoplasmic domain structures of Kir2.1 and Kir3.1 show sites for modulating gating and rectificationQ46536039
Differential voltage-dependent K+ channel responses during proliferation and activation in macrophagesQ47684617
Relationship between Kir2.1/Kir2.3 activity and their distributions between cholesterol-rich and cholesterol-poor membrane domains.Q51017878
Hypercholesterolemia suppresses inwardly rectifying K+ channels in aortic endothelium in vitro and in vivo.Q51242120
Silent Inward Rectifier K + Channels in HypercholesterolemiaQ57374819
P433issue18
P407language of work or nameEnglishQ1860
P1104number of pages14
P304page(s)4025-4038
P577publication date2014-07-18
P1433published inJournal of PhysiologyQ7743612
P1476titleSilencing of Kir2 channels by caveolin-1: cross-talk with cholesterol
P478volume592

Reverse relations

cites work (P2860)
Q38819091Boosting the signal: Endothelial inward rectifier K+ channels
Q59341012Caveolin-3 Microdomain: Arrhythmia Implications for Potassium Inward Rectifier and Cardiac Sodium Channel
Q58801806Golgin-97 Targets Ectopically Expressed Inward Rectifying Potassium Channel, Kir2.1, to the -Golgi Network in COS-7 Cells
Q51744807Hypercholesterolemia-Induced Loss of Flow-Induced Vasodilation and Lesion Formation in Apolipoprotein E-Deficient Mice Critically Depend on Inwardly Rectifying K+ Channels.
Q34514622Interplay Between Lipid Modulators of Kir2 Channels: Cholesterol and PIP2.
Q47564800Inward Rectifier Potassium Channels (Kir2.x) and Caveolin-3 Domain-Specific Interaction: Implications for Purkinje Cell-Dependent Ventricular Arrhythmias.
Q47792775Inwardly rectifying K+ channels are major contributors to flow-induced vasodilatation in resistance arteries.
Q57044313Molecular Dynamics Simulations of Kir2.2 Interactions with an Ensemble of Cholesterol Molecules
Q47656632Perivascular adipose tissue and the dynamic regulation of Kv 7 and Kir channels: Implications for resistant hypertension
Q39195631Smooth Muscle Ion Channels and Regulation of Vascular Tone in Resistance Arteries and Arterioles
Q26864921Vascular inward rectifier K+ channels as external K+ sensors in the control of cerebral blood flow

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