Antigen-specific Treg cells in immunological tolerance: implications for allergic diseases.

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Antigen-specific Treg cells in immunological tolerance: implications for allergic diseases. is …
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scholarly articleQ13442814

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P356DOI10.12688/F1000RESEARCH.12650.1
P932PMC publication ID5765398
P698PubMed publication ID29375821

P50authorTalal A ChatilaQ60539789
Azza Abdel-GadirQ87628797
P2093author name stringAmir H Massoud
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A requisite role for induced regulatory T cells in tolerance based on expanding antigen receptor diversityQ24622687
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Control of regulatory T cell development by the transcription factor Foxp3Q27860489
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseasesQ28131652
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T cell-mediated oral tolerance is intact in germ-free miceQ82599417
Oral tolerance can be established via gap junction transfer of fed antigens from CX3CR1⁺ macrophages to CD103⁺ dendritic cellsQ87163156
Interleukin-6 receptor blockade enhances CD39+ regulatory T cell development in rheumatoid arthritis and in experimental arthritisQ87248599
Oral immunotherapy for the treatment of food allergyQ38271442
Thymus medulla fosters generation of natural Treg cells, invariant γδ T cells, and invariant NKT cells: what we learn from intrathymic migrationQ38330134
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An essential role of the transcription factor GATA-3 for the function of regulatory T cellsQ38586280
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Protein kinase CK2 enables regulatory T cells to suppress excessive TH2 responses in vivo.Q38918816
Regulatory T cells in allergic diseases.Q38946820
Identification of novel immune phenotypes for allergic and nonallergic childhood asthmaQ39128198
Regulatory T Cell Specificity Directs Tolerance versus Allergy against Aeroantigens in HumansQ39257312
Alveolar macrophages contribute to respiratory tolerance by inducing FoxP3 expression in naive T cellsQ39451665
Epicutaneous immunotherapy induces gastrointestinal LAP+ regulatory T cells and prevents food-induced anaphylaxisQ39601654
Antigen-specific Treg regulate Th17-mediated lung neutrophilic inflammation, B-cell recruitment and polymeric IgA and IgM levels in the airwaysQ39910461
Helicobacter species are potent drivers of colonic T cell responses in homeostasis and inflammationQ40124338
Response to self antigen imprints regulatory memory in tissuesQ40573313
Memory of Inflammation in Regulatory T CellsQ41266256
TCR repertoire and Foxp3 expression define functionally distinct subsets of CD4+ regulatory T cellsQ41810922
Anti-TNF-alpha therapy induces a distinct regulatory T cell population in patients with rheumatoid arthritis via TGF-betaQ42096868
Regulatory T cell development in the absence of functional Foxp3.Q44440268
Continuous T cell receptor signaling required for synapse maintenance and full effector potentialQ46556005
A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanismQ29614266
Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiotaQ29614272
Regulatory T cells and immune toleranceQ29616864
Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cellsQ29618126
X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfyQ29619109
Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-selfQ29619194
The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3Q29619324
Molecular antagonism and plasticity of regulatory and inflammatory T cell programsQ29619478
The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiotaQ29619977
CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearanceQ29620412
Decreased gut microbiota diversity, delayed Bacteroidetes colonisation and reduced Th1 responses in infants delivered by caesarean sectionQ30221761
Dynamic imaging of dendritic cell extension into the small bowel lumen in response to epithelial cell TLR engagementQ33265418
Commensal bacteria at the interface of host metabolism and the immune systemQ33578547
Interleukin 4 promotes the development of ex-Foxp3 Th2 cells during immunity to intestinal helminthsQ33769549
Oral tolerance in the absence of naturally occurring TregsQ33840440
Does the use of antibiotics in early childhood increase the risk of asthma and allergic disease?Q33924563
In vivo regulation of the allergic response by the IL-4 receptor alpha chain immunoreceptor tyrosine-based inhibitory motifQ33930790
Peanut oral immunotherapy results in increased antigen-induced regulatory T-cell function and hypomethylation of forkhead box protein 3 (FOXP3).Q33999649
Immunoglobulin E signal inhibition during allergen ingestion leads to reversal of established food allergy and induction of regulatory T cellsQ34007974
The 'hygiene hypothesis' for autoimmune and allergic diseases: an updateQ34111851
Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantationQ34162461
Regulatory T cells and their roles in immune dysregulation and allergy.Q34166571
Is there an association between microbial exposure and food allergy? A systematic review.Q34338632
Oral and sublingual immunotherapy for food allergy: current progress and future directions.Q34366285
A special population of regulatory T cells potentiates muscle repairQ34390308
Transforming growth factor-beta controls development, homeostasis, and tolerance of T cells by regulatory T cell-dependent and -independent mechanismsQ34570917
T-cell regulation by CD28 and CTLA-4.Q34572202
All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulationQ34580976
Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfacesQ34590015
Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunityQ34596060
Antigen-specific peripheral shaping of the natural regulatory T cell populationQ34601484
IgE-mediated systemic anaphylaxis and impaired tolerance to food antigens in mice with enhanced IL-4 receptor signalingQ34629109
Lung-resident tissue macrophages generate Foxp3+ regulatory T cells and promote airway toleranceQ34649990
Short-chain fatty acids induce both effector and regulatory T cells by suppression of histone deacetylases and regulation of the mTOR-S6K pathwayQ34681642
Regulatory T cells and immune tolerance in the intestineQ34789108
Models of self-peptide sampling by developing T cells identify candidate mechanisms of thymic selectionQ34916448
Control of regulatory T cells and airway tolerance by lung macrophages and dendritic cellsQ34984616
Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivoQ37312884
The T-cell receptor repertoire of regulatory T cellsQ37364109
A microbiota signature associated with experimental food allergy promotes allergic sensitization and anaphylaxisQ37387330
A central role for induced regulatory T cells in tolerance induction in experimental colitisQ37390209
Regulatory T cell memoryQ37420611
Natural and adaptive foxp3+ regulatory T cells: more of the same or a division of labor?Q37493607
Cutting edge: Self-antigen controls the balance between effector and regulatory T cells in peripheral tissuesQ37585817
Direct control of regulatory T cells by keratinocytesQ37643819
Diversity in T cell memory: an embarrassment of richesQ37671907
From the thymus to longevity in the periphery.Q37727632
Epidemiology of food allergyQ37828758
Induced CD4+Foxp3+ regulatory T cells in immune toleranceQ37973769
Selection of regulatory T cells in the thymusQ37982939
Instability of Foxp3 expression limits the ability of induced regulatory T cells to mitigate graft versus host diseaseQ35053246
Lung microbiota promotes tolerance to allergens in neonates via PD-L1.Q35165937
Regulatory T cell reprogramming toward a Th2-cell-like lineage impairs oral tolerance and promotes food allergyQ35196374
Microbiome diversity and asthma and allergy riskQ35230090
Peripheral education of the immune system by colonic commensal microbiota.Q35341308
GATA3 controls Foxp3⁺ regulatory T cell fate during inflammation in miceQ35484886
MUCOSAL IMMUNOLOGY. The microbiota regulates type 2 immunity through RORγt⁺ T cellsQ35687488
MUCOSAL IMMUNOLOGY. Individual intestinal symbionts induce a distinct population of RORγ⁺ regulatory T cells.Q35745717
Requirement of full TCR repertoire for regulatory T cells to maintain intestinal homeostasisQ35792972
Changes in antigen-specific T-cell number and function during oral desensitization in cow's milk allergy enabled with omalizumabQ35894673
Dietary antigens limit mucosal immunity by inducing regulatory T cells in the small intestine.Q35907784
MyD88 Adaptor-Dependent Microbial Sensing by Regulatory T Cells Promotes Mucosal Tolerance and Enforces CommensalismQ35984305
Development and maintenance of intestinal regulatory T cellsQ35992122
Regulatory T cells in asthmaQ36064548
Type 1 regulatory T cells: a new mechanism of peripheral immune toleranceQ36085099
A Distinct Function of Regulatory T Cells in Tissue ProtectionQ36155521
A commensal symbiotic factor derived from Bacteroides fragilis promotes human CD39(+)Foxp3(+) T cells and Treg functionQ36191738
Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cellsQ36278051
Pregnancy imprints regulatory memory that sustains anergy to fetal antigenQ36300965
CD4+ T Cell Tolerance to Tissue-Restricted Self Antigens Is Mediated by Antigen-Specific Regulatory T Cells Rather Than DeletionQ36304455
Extrathymically generated regulatory T cells control mucosal TH2 inflammationQ36359813
Number of T reg cells that differentiate does not increase upon encounter of agonist ligand on thymic epithelial cells.Q36399562
Microbe sampling by mucosal dendritic cells is a discrete, MyD88-independent step in DeltainvG S. Typhimurium colitisQ36502893
The TCR repertoires of regulatory and conventional T cells specific for the same foreign antigen are distinctQ36511889
Antigen-specific memory regulatory CD4+Foxp3+ T cells control memory responses to influenza virus infectionQ36717926
Early infection with respiratory syncytial virus impairs regulatory T cell function and increases susceptibility to allergic asthmaQ36810987
Classical dendritic cells are required for dietary antigen-mediated induction of peripheral T(reg) cells and toleranceQ36814061
TCR signaling by conventional CD4+ T cells is required for optimal maintenance of peripheral regulatory T cell numbersQ36933643
Induced and natural regulatory T cells in the development of inflammatory bowel diseaseQ36948341
Differentiation of regulatory Foxp3+ T cells in the thymic cortexQ36954436
Control of T cell fates and immune tolerance by p38α signaling in mucosal CD103+ dendritic cellsQ36986269
Oral tolerance, food allergy, and immunotherapy: implications for future treatmentQ37138202
Regulatory T cell differentiation of thymocytes does not require a dedicated antigen-presenting cell but is under T cell-intrinsic developmental control.Q37223249
An asthma-associated IL4R variant exacerbates airway inflammation by promoting conversion of regulatory T cells to TH17-like cellsQ37239169
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P921main subjectimmunologyQ101929
P304page(s)38
P577publication date2018-01-10
P1433published inF1000ResearchQ27701587
P1476titleAntigen-specific Treg cells in immunological tolerance: implications for allergic diseases
P478volume7

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cites work (P2860)
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