A central role for induced regulatory T cells in tolerance induction in experimental colitis

scientific article published on March 2009

A central role for induced regulatory T cells in tolerance induction in experimental colitis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4049/JIMMUNOL.0802535
P932PMC publication ID2763205
P698PubMed publication ID19265124
P5875ResearchGate publication ID24180960

P50authorNita H. SalzmanQ42568978
Talal A ChatilaQ60539789
Dipica HaribhaiQ124216890
Jennifer ZiegelbauerQ124216891
P2093author name stringWen Lin
Pippa M Simpson
Calvin B Williams
Shun-Hwa Li
Brandon Edwards
Marc R Carlson
P2860cites workBioconductor: open software development for computational biology and bioinformaticsQ21194861
Allergic dysregulation and hyperimmunoglobulinemia E in Foxp3 mutant miceQ24293865
Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early deathQ24563654
Helios, a T cell-restricted Ikaros family member that quantitatively associates with Ikaros at centromeric heterochromatinQ24605629
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3Q24672849
Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory diseaseQ28202655
The chromatin remodeler Mi-2beta is required for CD4 expression and T cell developmentQ28266281
Helios, a novel dimerization partner of Ikaros expressed in the earliest hematopoietic progenitorsQ28268827
Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptorQ28273769
Where CD4+CD25+ T reg cells impinge on autoimmune diabetesQ28506933
Regulatory T cell lineage specification by the forkhead transcription factor foxp3Q28510328
An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoiresQ28590409
Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7Q28591451
Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptorQ28593665
A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanismQ29614266
Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acidQ29615586
Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acidQ29619479
Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responsesQ29619908
Epigenetic control of the foxp3 locus in regulatory T cellsQ33273617
Cutting edge: cure of colitis by CD4+CD25+ regulatory T cellsQ34189120
Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid miceQ34321778
In vivo instruction of suppressor commitment in naive T cellsQ34548023
TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cellsQ34556464
Transforming growth factor-beta controls development, homeostasis, and tolerance of T cells by regulatory T cell-dependent and -independent mechanismsQ34570917
Cutting Edge: IL-2 is essential for TGF-beta-mediated induction of Foxp3+ T regulatory cellsQ34577919
Predominant interaction of both Ikaros and Helios with the NuRD complex in immature thymocytesQ34660281
Inflammatory bowel disease in C.B-17 scid mice reconstituted with the CD45RBhigh subset of CD4+ T cells.Q35773643
TCR-based lineage tracing: no evidence for conversion of conventional into regulatory T cells in response to a natural self-antigen in pancreatic isletsQ36229637
Sequential development of interleukin 2-dependent effector and regulatory T cells in response to endogenous systemic antigenQ36403106
Developmental regulation of Foxp3 expression during ontogeny.Q36403564
Regulatory T cells suppress systemic and mucosal immune activation to control intestinal inflammationQ36563545
Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans.Q36891917
Ligand-independent regulation of transforming growth factor beta1 expression and cell cycle progression by the aryl hydrocarbon receptor.Q38300363
Nonself-antigens are the cognate specificities of Foxp3+ regulatory T cellsQ42114183
Transforming growth factor beta induced FoxP3+ regulatory T cells suppress Th1 mediated experimental colitis.Q42844822
Regulatory T cell development in the absence of functional Foxp3.Q44440268
IL-2 is essential for TGF-beta to convert naive CD4+CD25- cells to CD25+Foxp3+ regulatory T cells and for expansion of these cellsQ46040716
DNA demethylation in the human FOXP3 locus discriminates regulatory T cells from activated FOXP3(+) conventional T cells.Q52924279
Foxp3-dependent and -independent molecules specific for CD25+CD4+ natural regulatory T cells revealed by DNA microarray analysis.Q54597061
Foxp3-dependent programme of regulatory T-cell differentiationQ59084714
Foxp3 Transcription-Factor-Dependent and -Independent Regulation of the Regulatory T Cell Transcriptional SignatureQ61713917
CD25+ CD4+ T cells regulate the expansion of peripheral CD4 T cells through the production of IL-10Q73509865
Regulatory T cells dynamically control the primary immune response to foreign antigenQ79803360
Origin and T cell receptor diversity of Foxp3+CD4+CD25+ T cellsQ80034250
Recognition of the peripheral self by naturally arising CD25+ CD4+ T cell receptorsQ80444910
CD25- T cells generate CD25+Foxp3+ regulatory T cells by peripheral expansionQ81111400
Inducing and expanding regulatory T cell populations by foreign antigenQ81392563
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)3461-3468
P577publication date2009-03-01
P1433published inJournal of ImmunologyQ3521441
P1476titleA central role for induced regulatory T cells in tolerance induction in experimental colitis
P478volume182

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