Chk1 and 14-3-3 proteins inhibit atypical E2Fs to prevent a permanent cell cycle arrest

scientific article

Chk1 and 14-3-3 proteins inhibit atypical E2Fs to prevent a permanent cell cycle arrest is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.15252/EMBJ.201797877
P932PMC publication ID5830916
P698PubMed publication ID29363506

P50authorAlain de BruinQ32422181
Harmjan VosQ57041767
Bart WestendorpQ93052648
P2093author name stringJing Chen
Boudewijn Mt Burgering
Robert M van Es
Ruixue Yuan
P2860cites workE2F7, a novel target, is up-regulated by p53 and mediates DNA damage-dependent transcriptional repressionQ24293588
MDC1 is a mediator of the mammalian DNA damage checkpointQ24296229
Chk2 activates E2F-1 in response to DNA damageQ24300634
DNA-damage response control of E2F7 and E2F8Q24306816
Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserineQ24322674
Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpointsQ24538300
The DNA-damage response in human biology and diseaseQ24606586
Amplification of LAPTM4B and YWHAZ contributes to chemotherapy resistance and recurrence of breast cancerQ24644185
Cdc7-Dbf4 and the human S checkpoint response to UVCQ24672815
The DNA Damage Response: Making It Safe to Play with KnivesQ27861055
Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like proteinQ27933995
Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25Q28247761
14-3-3 zeta as novel molecular target for cancer therapyQ28264735
Checkpoint kinase 1 in DNA damage response and cell cycle regulationQ28287480
Roles of Chk1 in cell biology and cancer therapyQ28289548
Isoforms of 14-3-3 protein can form homo- and heterodimers in vivo and in vitro: implications for function as adapter proteinsQ28293607
The radiosensitizing agent 7-hydroxystaurosporine (UCN-01) inhibits the DNA damage checkpoint kinase hChk1Q28377992
Cloning and characterization of mouse E2F8, a novel mammalian E2F family member capable of blocking cellular proliferationQ28505582
Identification and characterization of E2F7, a novel mammalian E2F family member capable of blocking cellular proliferationQ28510107
14-3-3 proteins integrate E2F activity with the DNA damage response.Q28512082
E2F7 represses a network of oscillating cell cycle genes to control S-phase progressionQ28592916
Rapid destruction of human Cdc25A in response to DNA damageQ28611930
The structural basis for 14-3-3:phosphopeptide binding specificityQ29547190
The DNA replication checkpoint response stabilizes stalled replication forksQ29618306
Temporally coordinated assembly and disassembly of replication factories in the absence of DNA synthesisQ30939848
Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakageQ31160033
E2F3 is a mediator of DNA damage-induced apoptosisQ33558803
The G(2) DNA damage checkpoint targets both Wee1 and Cdc25.Q33898498
14-3-3 proteins: regulation of subcellular localization by molecular interferenceQ34127838
New insights into checkpoint kinase 1 in the DNA damage response signaling networkQ34129155
Chk1 promotes replication fork progression by controlling replication initiationQ34136566
Different roles for nonhomologous end joining and homologous recombination following replication arrest in mammalian cellsQ34284545
Unlocking the code of 14-3-3.Q35748302
14-3-3ζ coordinates adipogenesis of visceral fat.Q35941573
Proteogenomics connects somatic mutations to signalling in breast cancerQ36037203
The atypical E2F family member E2F7 couples the p53 and RB pathways during cellular senescenceQ36114088
E2F8 as a Novel Therapeutic Target for Lung CancerQ36294944
Feedback regulation between atypical E2Fs and APC/CCdh1 coordinates cell cycle progressionQ36636175
E2f8 mediates tumor suppression in postnatal liver developmentQ37137905
14-3-3ζ regulates the mitochondrial respiratory reserve linked to platelet phosphatidylserine exposure and procoagulant functionQ37314976
Copy number gain and oncogenic activity of YWHAZ/14-3-3zeta in head and neck squamous cell carcinomaQ37372476
A role for 14-3-3 tau in E2F1 stabilization and DNA damage-induced apoptosisQ37523583
Synergistic functions of E2F7 and E2F8 are critical to suppress stress-induced skin cancer.Q37644047
Chk1 inhibits E2F6 repressor function in response to replication stress to maintain cell-cycle transcriptionQ38633360
E2F-7 couples DNA damage-dependent transcription with the DNA repair process.Q39105557
Toward a comprehensive characterization of a human cancer cell phosphoproteome.Q39237219
A novel function of YWHAZ/β-catenin axis in promoting epithelial-mesenchymal transition and lung cancer metastasis.Q39293295
Suppressed miR-424 expression via upregulation of target gene Chk1 contributes to the progression of cervical cancerQ39370408
A new nonpeptidic inhibitor of 14-3-3 induces apoptotic cell death in chronic myeloid leukemia sensitive or resistant to imatinibQ39637274
Chk1-deficient tumour cells are viable but exhibit multiple checkpoint and survival defectsQ39698998
E2F8 contributes to human hepatocellular carcinoma via regulating cell proliferation.Q39752834
Sustained E2F-Dependent Transcription Is a Key Mechanism to Prevent Replication-Stress-Induced DNA Damage.Q39781748
E2F7 can regulate proliferation, differentiation, and apoptotic responses in human keratinocytes: implications for cutaneous squamous cell carcinoma formationQ39882791
The E2F-regulated gene Chk1 is highly expressed in triple-negative estrogen receptor /progesterone receptor /HER-2 breast carcinomasQ40105586
Nuclear localization of Cdc25 is regulated by DNA damage and a 14-3-3 proteinQ46098415
ATR-CHK1-E2F3 signaling transactivates human ribonucleotide reductase small subunit M2 for DNA repair induced by the chemical carcinogen MNNG.Q54211934
UCN-01-mediated G1 arrest in normal but not tumor breast cells is pRb-dependent and p53-independentQ73088364
P4510describes a project that usesRStudioQ4798119
P433issue5
P407language of work or nameEnglishQ1860
P577publication date2018-01-23
P1433published inThe EMBO JournalQ1278554
P1476titleChk1 and 14-3-3 proteins inhibit atypical E2Fs to prevent a permanent cell cycle arrest
P478volume37

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cites work (P2860)
Q93052652Cyclin F-dependent degradation of E2F7 is critical for DNA repair and G2-phase progression
Q89883637Identification of the Different Roles and Potential Mechanisms of T Isoforms in the Tumor Recurrence and Cell Cycle of Chordomas
Q90387479Loss of E2F7 confers resistance to poly-ADP-ribose polymerase (PARP) inhibitors in BRCA2-deficient cells
Q57793036The Impact of Replication Stress in Human Papillomavirus Pathogenesis
Q91752429The broken cycle: E2F dysfunction in cancer
Q55172809The live cell DNA stain SiR-Hoechst induces DNA damage responses and impairs cell cycle progression.

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