| scholarly article | Q13442814 |
| P356 | DOI | 10.1038/ONC.2012.121 |
| P2888 | exact match | https://scigraph.springernature.com/pub.10.1038/onc.2012.121 |
| P698 | PubMed publication ID | 22469983 |
| P2093 | author name string | J Xu | |
| X Wang | |||
| Y Li | |||
| X Xie | |||
| W Lu | |||
| B Cheng | |||
| F Wang | |||
| C Zhou | |||
| F Ye | |||
| P2860 | cites work | Ultra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumours and matched controls | Q21245318 |
| Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints | Q24538300 | ||
| miRBase: microRNA sequences, targets and gene nomenclature | Q24538656 | ||
| MicroRNAs: target recognition and regulatory functions | Q24609584 | ||
| miR-16 family induces cell cycle arrest by regulating multiple cell cycle genes. | Q24653347 | ||
| Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008 | Q27860674 | ||
| The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14 | Q27860849 | ||
| Identification of novel genes coding for small expressed RNAs | Q27860917 | ||
| Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells | Q28256740 | ||
| Mammalian G1- and S-phase checkpoints in response to DNA damage | Q29013238 | ||
| MicroRNAs in Cancer | Q29615539 | ||
| Repression of protein synthesis by miRNAs: how many mechanisms? | Q29620361 | ||
| MiR-322/424 and -503 are induced during muscle differentiation and promote cell cycle quiescence and differentiation by down-regulation of Cdc25A. | Q30434790 | ||
| A small piece in the cancer puzzle: microRNAs as tumor suppressors and oncogenes | Q33343251 | ||
| Aberrant expression of oncogenic and tumor-suppressive microRNAs in cervical cancer is required for cancer cell growth | Q33348593 | ||
| MicroRNA profiling of human intrahepatic cholangiocarcinoma cell lines reveals biliary epithelial cell-specific microRNAs | Q33503530 | ||
| microRNA profiling in Epstein-Barr virus-associated B-cell lymphoma | Q33742946 | ||
| Serine-345 is required for Rad3-dependent phosphorylation and function of checkpoint kinase Chk1 in fission yeast | Q33944461 | ||
| miRNA deregulation by epigenetic silencing disrupts suppression of the oncogene PLAG1 in chronic lymphocytic leukemia | Q34079123 | ||
| OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma. | Q34130311 | ||
| Hypoxia-induced microRNA-424 expression in human endothelial cells regulates HIF-α isoforms and promotes angiogenesis | Q34145466 | ||
| RNAi screen of the protein kinome identifies checkpoint kinase 1 (CHK1) as a therapeutic target in neuroblastoma | Q34602599 | ||
| microRNA-92a promotes lymph node metastasis of human esophageal squamous cell carcinoma via E-cadherin | Q34695995 | ||
| MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis | Q34835189 | ||
| Induction of microRNAs, mir-155, mir-222, mir-424 and mir-503, promotes monocytic differentiation through combinatorial regulation | Q35015735 | ||
| RBM3-regulated genes promote DNA integrity and affect clinical outcome in epithelial ovarian cancer | Q35116809 | ||
| ZBRK1 acts as a metastatic suppressor by directly regulating MMP9 in cervical cancer | Q35610737 | ||
| The interplay between the master transcription factor PU.1 and miR-424 regulates human monocyte/macrophage differentiation. | Q36288893 | ||
| Matrix metalloproteinases and tumor metastasis | Q36471104 | ||
| miR-21 as a key regulator of oncogenic processes | Q37554678 | ||
| Chk1-deficient tumour cells are viable but exhibit multiple checkpoint and survival defects | Q39698998 | ||
| Involvement of ATM-mediated Chk1/2 and JNK kinase signaling activation in HKH40A-induced cell growth inhibition. | Q39837434 | ||
| MiR-21 indicates poor prognosis in tongue squamous cell carcinomas as an apoptosis inhibitor | Q39840690 | ||
| The E2F-regulated gene Chk1 is highly expressed in triple-negative estrogen receptor /progesterone receptor /HER-2 breast carcinomas | Q40105586 | ||
| Identification of suitable reference genes for measurement of gene expression in human cervical tissues | Q42990032 | ||
| Progressive miRNA expression profiles in cervical carcinogenesis and identification of HPV-related target genes for miR-29. | Q53253196 | ||
| Influence of chk1 and plk1 silencing on radiation- or cisplatin-induced cytotoxicity in human malignant cells. | Q53603657 | ||
| Expression of MMP9 and CD147 in invasive squamous cell carcinoma of the uterine cervix and their implication. | Q54476793 | ||
| A proteomics analysis of cell signaling alterations in colorectal cancer | Q81234559 | ||
| Expression of leukaemia inhibitory factor in epithelial ovarian carcinoma: correlation with clinical characteristics | Q81425182 | ||
| Initial study of microRNA expression profiles of colonic cancer without lymph node metastasis | Q82783887 | ||
| Identification of suitable reference genes for gene expression studies of human serous ovarian cancer by real-time polymerase chain reaction | Q84270183 | ||
| Identification of glia maturation factor beta as an independent prognostic predictor for serous ovarian cancer | Q84402610 | ||
| P433 | issue | 8 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | cervix uterine cancer | Q160105 |
| P304 | page(s) | 976-987 | |
| P577 | publication date | 2012-04-02 | |
| P1433 | published in | Oncogene | Q1568657 |
| P1476 | title | Suppressed miR-424 expression via upregulation of target gene Chk1 contributes to the progression of cervical cancer | |
| P478 | volume | 32 |
| Q34049716 | A Comprehensive Review of Dysregulated miRNAs Involved in Cervical Cancer. |
| Q41346041 | A genome-wide microRNA profiling indicates miR-424-5p and miR-503-5p as regulators of ALK expression in neuroblastoma. |
| Q35919841 | A single nucleotide polymorphism in primary-microRNA-146a reduces the expression of mature microRNA-146a in patients with Alzheimer's disease and is associated with the pathogenesis of Alzheimer's disease |
| Q38511703 | A systematic study on dysregulated microRNAs in cervical cancer development |
| Q92134471 | An Emerging Class of Long Non-coding RNA With Oncogenic Role Arises From the snoRNA Host Genes |
| Q33635896 | Ataxin-3 promotes genome integrity by stabilizing Chk1. |
| Q40079471 | Biosemantics guided gene expression profiling of Sjögren's syndrome: a comparative analysis with systemic lupus erythematosus and rheumatoid arthritis |
| Q38379668 | CHK1 expression in Gastric Cancer is modulated by p53 and RB1/E2F1: implications in chemo/radiotherapy response |
| Q38965035 | CHK1 overexpression in T-cell acute lymphoblastic leukemia is essential for proliferation and survival by preventing excessive replication stress. |
| Q37327810 | CUL2 overexpression driven by CUL2/E2F1/miR-424 regulatory loop promotes HPV16 E7 induced cervical carcinogenesis |
| Q37693690 | Cell cycle proteins as promising targets in cancer therapy |
| Q42517538 | Checkpoint Kinase 1 Expression Predicts Poor Prognosis in Nigerian Breast Cancer Patients |
| Q48177734 | Chk1 and 14-3-3 proteins inhibit atypical E2Fs to prevent a permanent cell cycle arrest |
| Q34028486 | Chk1-induced CCNB1 overexpression promotes cell proliferation and tumor growth in human colorectal cancer |
| Q38973406 | Circular RNA ciRS-7-A Promising Prognostic Biomarker and a Potential Therapeutic Target in Colorectal Cancer. |
| Q45612220 | Clinical Impact of microRNAs Associated With Cancer Stem Cells as a Prognostic Factor in Ovarian Carcinoma |
| Q90481284 | Clinical and functional significance of CHK1-S, an alternatively spliced isoform of the CHK1 gene, in hepatocellular carcinoma |
| Q64106586 | Clinically Relevant Biomarker Discovery in High-Risk Recurrent Neuroblastoma |
| Q37065840 | Conformational Change of Human Checkpoint Kinase 1 (Chk1) Induced by DNA Damage |
| Q99630249 | Cyto-biological effects of microRNA-424-5p on human colorectal cancer cells |
| Q48114614 | DNA methylation regulated microRNAs in human cervical cancer. |
| Q47634492 | DNA methyltransferase 3a modulates chemosensitivity to gemcitabine and oxaliplatin via CHK1 and AKT in p53‑deficient pancreatic cancer cells |
| Q36414395 | DNMT1-dependent suppression of microRNA424 regulates tumor progression in human bladder cancer |
| Q30241934 | Deregulated miRNAs in human cervical cancer: functional importance and potential clinical use. |
| Q41837402 | Deregulation of the miRNAs expression in cervical cancer: human papillomavirus implications |
| Q35835227 | Down regulation of MiR-93 contributes to endometriosis through targeting MMP3 and VEGFA |
| Q37392777 | Downregulated miR-31 level associates with poor prognosis of gastric cancer and its restoration suppresses tumor cell malignant phenotypes by inhibiting E2F2. |
| Q38189740 | Epigenetics and cervical cancer: from pathogenesis to therapy |
| Q54962616 | Exploration of the molecular mechanisms of cervical cancer based on mRNA expression profiles and predicted microRNA interactions. |
| Q37635048 | FOXO1-suppressed miR-424 regulates the proliferation and osteogenic differentiation of MSCs by targeting FGF2 under oxidative stress |
| Q90363489 | Gene Expression Alterations and Molecular Analysis of CHEK1 in Solid Tumors |
| Q93361361 | H19X-encoded miR-424(322)/-503 cluster: emerging roles in cell differentiation, proliferation, plasticity and metabolism |
| Q34446691 | Hepatitis C virus represses the cellular antiviral response by upregulating the expression of signal transducer and activator of transcription 3 through sponging microRNA‑122 |
| Q39869306 | IL-8 induces miR-424-5p expression and modulates SOCS2/STAT5 signaling pathway in oral squamous cell carcinoma |
| Q28389846 | Identification of a core miRNA-pathway regulatory network in glioma by therapeutically targeting miR-181d, miR-21, miR-23b, β-Catenin, CBP, and STAT3 |
| Q92045294 | Inhibition of CHK 1 (Checkpoint Kinase 1) Elicits Therapeutic Effects in Pulmonary Arterial Hypertension |
| Q34584599 | Integrated microRNA and mRNA signatures associated with survival in triple negative breast cancer |
| Q30987198 | Integrative Analysis of MicroRNA and mRNA Data Reveals an Orchestrated Function of MicroRNAs in Skeletal Myocyte Differentiation in Response to TNF-α or IGF1. |
| Q35674157 | Let-7 miRNAs Modulate the Activation of NF-κB by Targeting TNFAIP3 and Are Involved in the Pathogenesis of Lupus Nephritis |
| Q36701100 | LncRNA OIP5-AS1/cyrano sponges RNA-binding protein HuR. |
| Q90353701 | LncRNA XIST depletion prevents cancer progression in invasive pituitary neuroendocrine tumor by inhibiting bFGF via upregulation of microRNA-424-5p |
| Q92302426 | Long Non-coding RNA PVT1 Competitively Binds MicroRNA-424-5p to Regulate CARM1 in Radiosensitivity of Non-Small-Cell Lung Cancer |
| Q53451121 | Long Noncoding RNA PVT1 Facilitates Cervical Cancer Progression via Negative Regulating of miR-424. |
| Q99603511 | Long non-coding RNA AGAP2-AS1 increases the invasiveness of papillary thyroid cancer |
| Q51474565 | Loss of MiR-424-3p, not miR-424-5p, confers chemoresistance through targeting YAP1 in non-small cell lung cancer. |
| Q92134710 | Low Expression of miR-424-3p is Highly Correlated with Clinical Failure in Prostate Cancer |
| Q50983395 | Meta-analysis of microRNA expression profiling studies in human cervical cancer. |
| Q41627612 | MiR-101 inhibits ovarian carcinogenesis by repressing the expression of brain-derived neurotrophic factor |
| Q87487172 | MiR-199a is overexpressed in plasma of type 2 diabetes patients which contributes to type 2 diabetes by targeting GLUT4 |
| Q41412976 | MiR-19a overexpression contributes to heart failure through targeting ADRB1. |
| Q34993681 | MiR-30a upregulates BCL2A1, IER3 and cyclin D2 expression by targeting FOXL2 |
| Q38784189 | MiR-424 functions as a tumor suppressor in glioma cells and is down-regulated by DNA methylation |
| Q64111543 | MiR-424 is over-expressed and attenuates ischemia-reperfusion kidney injury via p53 and death receptor 6 pathway |
| Q28393361 | MiR-424-5p reversed epithelial-mesenchymal transition of anchorage-independent HCC cells by directly targeting ICAT and suppressed HCC progression |
| Q61805848 | MiRNA detection in cervical exfoliated cells for missed high-grade lesions in women with LSIL/CIN1 diagnosis after colposcopy-guided biopsy |
| Q34299702 | MicroRNA detection in cervical exfoliated cells as a triage for human papillomavirus-positive women |
| Q36094121 | MicroRNA expression profiles of cancer stem cells in head and neck squamous cell carcinoma |
| Q35128098 | MicroRNA-125b upregulation confers aromatase inhibitor resistance and is a novel marker of poor prognosis in breast cancer |
| Q37564508 | MicroRNA-218 inhibits EMT, migration and invasion by targeting SFMBT1 and DCUN1D1 in cervical cancer. |
| Q52681887 | MicroRNA-378 enhances migration and invasion in cervical cancer by directly targeting autophagy-related protein 12. |
| Q39154906 | MicroRNA-424-5p suppresses the expression of SOCS6 in pancreatic cancer |
| Q49476088 | MicroRNA-424/E2F6 feedback loop modulates cell invasion, migration and EMT in endometrial carcinoma. |
| Q47389746 | MicroRNA-497 Accelerates Apoptosis While Inhibiting Proliferation, Migration, and Invasion through negative regulation of the MAPK/ERK signaling pathway via RAF-1. |
| Q45925107 | MicroRNA-7 downregulates XIAP expression to suppress cell growth and promote apoptosis in cervical cancer cells. |
| Q54213961 | MicroRNA-92a promotes tumor growth and suppresses immune function through activation of MAPK/ERK signaling pathway by inhibiting PTEN in mice bearing U14 cervical cancer. |
| Q38088117 | MicroRNAs Involved in Anti-Tumour Immunity |
| Q35207669 | MicroRNAs in pulmonary arterial hypertension |
| Q40156531 | MicroRNAs overexpressed in ovarian ALDH1-positive cells are associated with chemoresistance |
| Q39246781 | Microarray analysis revealed markedly differential miRNA expression profiles in cervical intraepithelial neoplasias and invasive squamous cell carcinoma |
| Q27001000 | Multistep model of cervical cancer: participation of miRNAs and coding genes |
| Q36952911 | Nip the HPV encoded evil in the cancer bud: HPV reshapes TRAILs and signaling landscapes |
| Q38831430 | PBX3 is targeted by multiple miRNAs and is essential for liver tumour-initiating cells |
| Q41138134 | Reduced miR-9 and miR-181a expression down-regulates Bim concentration and promote osteoclasts survival |
| Q43120247 | Reduced mir-29b-3p expression up-regulate CDK6 and contributes to IgA nephropathy |
| Q37282882 | Regulation of epithelial plasticity by miR-424 and miR-200 in a new prostate cancer metastasis model |
| Q35133520 | Retracted: MicroRNA-424 Is Down-Regulated in Hepatocellular Carcinoma and Suppresses Cell Migration and Invasion through c-Myb |
| Q38258014 | Role of microRNAs in cancers of the female reproductive tract: insights from recent clinical and experimental discovery studies |
| Q28289548 | Roles of Chk1 in cell biology and cancer therapy |
| Q39137856 | Simultaneously expressed miR-424 and miR-381 synergistically suppress the proliferation and survival of renal cancer cells---Cdc2 activity is up-regulated by targeting WEE1. |
| Q41924177 | Suppression of MicroRNA 424 Levels by Human Papillomaviruses Is Necessary for Differentiation-Dependent Genome Amplification |
| Q27023204 | Targeting DNA damage response in cancer therapy |
| Q41239908 | Targeting MicroRNAs in Prostate Cancer Radiotherapy |
| Q47139126 | The Mechanism of Synchronous Precise Regulation of Two Shrimp White Spot Syndrome Virus Targets by a Viral MicroRNA. |
| Q90179394 | The Role of microRNAs, Long Non-coding RNAs, and Circular RNAs in Cervical Cancer |
| Q33588077 | The miR-424(322)/503 cluster orchestrates remodeling of the epithelium in the involuting mammary gland. |
| Q33826132 | The unique expression and function of miR-424 in human placental trophoblasts |
| Q26745686 | Trial Watch: Targeting ATM-CHK2 and ATR-CHK1 pathways for anticancer therapy |
| Q38829529 | Tumor Necrosis Factor Alpha and Insulin-Like Growth Factor 1 Induced Modifications of the Gene Expression Kinetics of Differentiating Skeletal Muscle Cells |
| Q39908852 | Tumor suppressive microRNA-424 inhibits osteosarcoma cell migration and invasion via targeting fatty acid synthase |
| Q30543779 | Tumor suppressor function of miR-483-3p on squamous cell carcinomas due to its pro-apoptotic properties |
| Q48140189 | Tumour-suppressive microRNA-424-5p directly targets CCNE1 as potential prognostic markers in epithelial ovarian cancer. |
| Q35173567 | Up-regulated miR-93 contributes to coronary atherosclerosis pathogenesis through targeting ABCA1. |
| Q36866964 | Upregulation of microRNA-224 is associated with aggressive progression and poor prognosis in human cervical cancer |
| Q89949998 | Urinary Exosomal MicroRNAs as Potential Non-invasive Biomarkers in Breast Cancer Detection |
| Q42245758 | Viral and cellular biomarkers in the diagnosis of cervical intraepithelial neoplasia and cancer |
| Q91714449 | ZEB1: A Critical Regulator of Cell Plasticity, DNA Damage Response, and Therapy Resistance |
| Q89939443 | lncRNA CCAT2 Enhanced Resistance of Glioma Cells Against Chemodrugs by Disturbing the Normal Function of miR-424 |
| Q35677296 | miR-1228 promotes the proliferation and metastasis of hepatoma cells through a p53 forward feedback loop |
| Q37057240 | miR-2861 acts as a tumor suppressor via targeting EGFR/AKT2/CCND1 pathway in cervical cancer induced by human papillomavirus virus 16 E6 |
| Q37213856 | miR-322/-503 cluster is expressed in the earliest cardiac progenitor cells and drives cardiomyocyte specification |
| Q37718390 | miR-424 acts as a tumor radiosensitizer by targeting aprataxin in cervical cancer |
| Q58579773 | miR-424 coordinates multilayered regulation of cell cycle progression to promote esophageal squamous cell carcinoma cell proliferation |
| Q59800180 | miR-424 targets AKT3 and PSAT1 and has a tumor-suppressive role in human colorectal cancer |
| Q38707925 | miR-424(322)/503 is a breast cancer tumor suppressor whose loss promotes resistance to chemotherapy |
| Q91829030 | miR-424-5p Promotes Proliferation, Migration and Invasion of Laryngeal Squamous Cell Carcinoma |
| Q43162081 | miRs-138 and -424 control palmitoylation-dependent CD95-mediated cell death by targeting acyl protein thioesterases 1 and 2 in CLL. |
| Q38998609 | microRNAs 424 and 503 are mediators of the anti-proliferative and anti-invasive action of the thyroid hormone receptor beta |
| Q37659973 | microRNAs are biomarkers of oncogenic human papillomavirus infections |
| Q38160950 | microRNAs in cancer cell response to ionizing radiation. |
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