Differential binding of tetrodotoxin and its derivatives to voltage-sensitive sodium channel subtypes (Nav 1.1 to Nav 1.7).

scientific article published on 18 August 2017

Differential binding of tetrodotoxin and its derivatives to voltage-sensitive sodium channel subtypes (Nav 1.1 to Nav 1.7). is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/BPH.13985
P932PMC publication ID5647187
P698PubMed publication ID28832970

P50authorYuko ChoQ59393016
Minoru WakamoriQ77696685
Keiichi KonokiQ86446496
Mari Yotsu-YamashitaQ87677978
Toshio NishikawaQ87851860
Tadaaki TsukamotoQ88833323
Masaatsu AdachiQ88833325
P2093author name stringShouta Tokoro
Yoshiki Satake
Ryo Sakakibara
Takuya Imazu
Yukie Chiba
Shunsuke Tsunogae
Tomoshi Yamada
P2860cites workFibroblast growth factor 14 is an intracellular modulator of voltage-gated sodium channelsQ24544162
TETRODOTOXIN BLOCKAGE OF SODIUM CONDUCTANCE INCREASE IN LOBSTER GIANT AXONSQ24672060
High-efficiency transformation of mammalian cells by plasmid DNAQ27860469
Selective blocking effects of 4,9-anhydrotetrodotoxin, purified from a crude mixture of tetrodotoxin analogues, on NaV1.6 channels and its chemical aspectsQ28084324
A sodium-channel mutation causes isolated cardiac conduction diseaseQ28203120
Recent progress in sodium channel modulators for painQ28244676
International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channelsQ28289125
Cardiac sodium channels (hH1) are intrinsically more sensitive to block by lidocaine than are skeletal muscle (mu 1) channelsQ28379079
The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligandsQ28603128
G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciencesQ29547562
Evidence for a role of Nav1.6 in facilitating increases in neuronal hyperexcitability during epileptogenesisQ30411051
The Concise Guide to PHARMACOLOGY 2015/16: Voltage-gated ion channels.Q30488645
Voltage-gated ion channels and gating modifier toxins.Q34161355
Tonic and phasic tetrodotoxin block of sodium channels with point mutations in the outer pore regionQ34170820
Interactions of the C-11 hydroxyl of tetrodotoxin with the sodium channel outer vestibuleQ34180126
First asymmetric total synthesis of tetrodotoxinQ34214527
An efficient total synthesis of optically active tetrodotoxinQ34348138
Brugada syndrome: report of the second consensus conference: endorsed by the Heart Rhythm Society and the European Heart Rhythm Association.Q34385271
Sodium channel mutations in epilepsy and other neurological disordersQ36216288
Marked difference in saxitoxin and tetrodotoxin affinity for the human nociceptive voltage-gated sodium channel (Nav1.7) [corrected]Q36397948
Actions of chiriquitoxin on frog skeletal muscle fibers and implications for the tetrodotoxin/saxitoxin receptorQ36434992
The role of sodium channels in chronic inflammatory and neuropathic painQ36456961
Characterization of Endogenous Sodium Channels in the ND7-23 Neuroblastoma Cell Line: Implications for Use as a Heterologous Ion Channel Expression System Suitable for Automated Patch Clamp ScreeningQ36707638
First Identification of 5,11-Dideoxytetrodotoxin in Marine Animals, and Characterization of Major Fragment Ions of Tetrodotoxin and Its Analogs by High Resolution ESI-MS/MSQ37155580
The voltage-gated sodium ion channel inhibitory activities of a new tetrodotoxin analogue, 4,4a-anhydrotetrodotoxin, and three other analogues evaluated by colorimetric cell-based assayQ38769215
A structural model of the tetrodotoxin and saxitoxin binding site of the Na+ channelQ39452849
Modeling P-loops domain of sodium channel: homology with potassium channels and interaction with ligandsQ40311449
Sodium channel mutation leading to saxitoxin resistance in clams increases risk of PSP.Q40437850
A quantitative and comparative study of the effects of a synthetic ciguatoxin CTX3C on the kinetic properties of voltage-dependent sodium channelsQ40545361
Biological activity of 8,11-dideoxytetrodotoxin: lethality to mice and the inhibitory activity to cytotoxicity of ouabain and veratridine in mouse neuroblastoma cells, Neuro-2aQ40628727
Chiriquitoxin, a new tool for mapping ionic channelsQ41550686
Experimental design and analysis and their reporting: new guidance for publication in BJP.Q42356330
Synthesis of 5- and 8-deoxytetrodotoxinQ47866203
Isolation of 6-deoxytetrodotoxin from the pufferfish, Takifugu pardalis, and a comparison of the effects of the C-6 and C-11 hydroxy groups of tetrodotoxin on its activityQ47895256
Total synthesis of chiriquitoxin, an analogue of tetrodotoxin isolated from the skin of a dart frogQ47920539
Resurgent-like currents in mouse vas deferens myocytes are mediated by NaV1.6 voltage-gated sodium channelsQ48130212
Effects of specific modifications of several hydroxyls of tetrodotoxin on its affinity to rat brain membraneQ48205069
A mutant of TTX-resistant cardiac sodium channels with TTX-sensitive propertiesQ48479782
The TTX metabolite 4,9-anhydro-TTX is a highly specific blocker of the Na(v1.6) voltage-dependent sodium channelQ48595392
An efficient total synthesis of optically active tetrodotoxin from levoglucosenoneQ48605656
Mapping the site of block by tetrodotoxin and saxitoxin of sodium channel II.Q50796508
Geographutoxin II, a novel peptide inhibitor of Na channels of skeletal muscles and autonomic nervesQ51803246
Saxitoxin and Tetrodotoxin: Comparison of Nerve Blocking MechanismQ52755804
Stereocontrolled Synthesis of (-)-5,11-DideoxytetrodotoxinQ73129520
P433issue21
P407language of work or nameEnglishQ1860
P304page(s)3881-3892
P577publication date2017-09-20
P1433published inBritish Journal of PharmacologyQ919631
P1476titleDifferential binding of tetrodotoxin and its derivatives to voltage-sensitive sodium channel subtypes (Nav 1.1 to Nav 1.7)
P478volume174

Reverse Query: null

Search more.