Risk-stratified therapy for children with FLT3-ITD-positive acute myeloid leukemia: results from the JPLSG AML-05 study.

scientific article published on 12 January 2018

Risk-stratified therapy for children with FLT3-ITD-positive acute myeloid leukemia: results from the JPLSG AML-05 study. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S12185-017-2395-X
P698PubMed publication ID29330746

P50authorAkira ShimadaQ57578382
P2093author name stringKeizo Horibe
Shotaro Iwamoto
Hiroyuki Takahashi
Takashi Taga
Yasuhide Hayashi
Katsuyoshi Koh
Hiroshi Moritake
Nobutaka Kiyokawa
Hideki Nakayama
Souichi Adachi
Kiminori Terui
Tomoyuki Watanabe
Daisuke Tomizawa
Shiro Tanaka
Yusuke Hara
Akitoshi Kinoshita
Akiko Moriya Saito
Hiroaki Goto
Yoshiyuki Kosaka
Akio Tawa
Kentaro Oki
Miho Yamada
Yuka Iijima-Yamashita
Shiba Norio
P2860cites workThe impact of FLT3 internal tandem duplication mutant level, number, size, and interaction with NPM1 mutations in a large cohort of young adult patients with acute myeloid leukemiaQ27851416
Impact of FLT3(ITD) mutant allele level on relapse risk in intermediate-risk acute myeloid leukemia.Q27853008
TET2 gene mutation is unfavorable prognostic factor in cytogenetically normal acute myeloid leukemia patients with NPM1+ and FLT3-ITD - mutationsQ27853009
Prevalence and prognostic significance of Flt3 internal tandem duplication in pediatric acute myeloid leukemiaQ31774863
NUP98/NSD1 and FLT3/ITD coexpression is more prevalent in younger AML patients and leads to induction failure: a COG and SWOG reportQ34318490
Clinical implications of FLT3 mutations in pediatric AML.Q35848876
FLT3 inhibitors for acute myeloid leukemia: a review of their efficacy and mechanisms of resistanceQ38101284
Differential impact of allelic ratio and insertion site in FLT3-ITD-positive AML with respect to allogeneic transplantationQ38422959
FLT3 Inhibitors in Acute Myeloid Leukemia: Current Status and Future DirectionsQ38675400
Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 MutationQ38712298
Internal tandem duplication of FLT3 deregulates proliferation and differentiation and confers resistance to the FLT3 inhibitor AC220 by Up-regulating RUNX1 expression in hematopoietic cellsQ40293334
Sorafenib and azacitidine as salvage therapy for relapse of FLT3-ITD mutated AML after allo-SCT.Q40454294
Haematopoietic cell transplantation with and without sorafenib maintenance for patients with FLT3-ITD acute myeloid leukaemia in first complete remissionQ40513646
WT1 mutation in pediatric patients with acute myeloid leukemia: a report from the Japanese Childhood AML Cooperative Study GroupQ44097808
NUP98-NSD1 gene fusion and its related gene expression signature are strongly associated with a poor prognosis in pediatric acute myeloid leukemiaQ44123939
FLT3 internal tandem duplication in 234 children with acute myeloid leukemia: prognostic significance and relation to cellular drug resistanceQ44484460
Insertion of FLT3 internal tandem duplication in the tyrosine kinase domain-1 is associated with resistance to chemotherapy and inferior outcome.Q45929224
Medium-sized FLT3 internal tandem duplications confer worse prognosis than short and long duplications in a non-elderly acute myeloid leukemia cohort.Q46576832
Positive Minimal Residual Disease of FLT3-ITD before Hematopoietic Stem Cell Transplantation Resulted in a Poor Prognosis of an Acute Myeloid Leukemia.Q51122226
RAS mutations are frequent in FAB type M4 and M5 of acute myeloid leukemia, and related to late relapse: a study of the Japanese Childhood AML Cooperative Study Group.Q53384430
High WT1 mRNA expression after induction chemotherapy and FLT3-ITD have prognostic impact in pediatric acute myeloid leukemia: a study of the Japanese Childhood AML Cooperative Study Group.Q54488953
Presence of FLT3-ITD and high BAALC expression are independent prognostic markers in childhood acute myeloid leukemiaQ57415017
Favorable outcome of patients with acute myeloid leukemia harboring a low-allelic burden FLT3-ITD mutation and concomitant NPM1 mutation: relevance to post-remission therapyQ62078641
Tandem duplications of MLL and FLT3 are correlated with poor prognoses in pediatric acute myeloid leukemia: a study of the Japanese childhood AML Cooperative Study GroupQ80974291
NUP98/NSD1 characterizes a novel poor prognostic group in acute myeloid leukemia with a distinct HOX gene expression patternQ84668776
Appropriate dose reduction in induction therapy is essential for the treatment of infants with acute myeloid leukemia: a report from the Japanese Pediatric Leukemia/Lymphoma Study GroupQ86040728
P433issue5
P921main subjectleukemiaQ29496
acute myeloid leukemiaQ264118
P304page(s)586-595
P577publication date2018-01-12
P1433published inInternational Journal of HematologyQ6051416
P1476titleRisk-stratified therapy for children with FLT3-ITD-positive acute myeloid leukemia: results from the JPLSG AML-05 study
P478volume107

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cites work (P2860)
Q58699070Identification of long non-coding RNA competing interactions and biological pathways associated with prognosis in pediatric and adolescent cytogenetically normal acute myeloid leukemia
Q92503784Nucleophosmin mutations confer an independent favorable prognostic impact in 869 pediatric patients with acute myeloid leukemia