Up-regulation of cathepsin S expression by HSP90 and 5-HT7 receptor-dependent serotonin signaling correlates with triple negativity of human breast cancer

scientific article published on 27 October 2016

Up-regulation of cathepsin S expression by HSP90 and 5-HT7 receptor-dependent serotonin signaling correlates with triple negativity of human breast cancer is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S10549-016-4027-1
P8608Fatcat IDrelease_qfpqxyymjrcsjb6iohifg4sjhy
P698PubMed publication ID27796714

P50authorYoung Kyung BaeQ80059987
Jung-Ae KimQ87859352
P2093author name stringJaya Gautam
P2860cites workHallmarks of Cancer: The Next GenerationQ22252312
Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistanceQ24645668
Role for cysteine protease cathepsins in heart disease: focus on biology and mechanisms with clinical implicationQ26864203
Hsp90 isoforms: functions, expression and clinical importanceQ28255212
Expression of cathepsins B and S in the progression of prostate carcinomaQ32160033
Degradation of HER2/neu by ANT2 shRNA suppresses migration and invasiveness of breast cancer cellsQ33637919
Distinct roles for cysteine cathepsin genes in multistage tumorigenesisQ34471105
Hsp90 inhibitors as novel cancer chemotherapeutic agentsQ34583912
Analysis of tumour- and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin SQ34599128
Cysteine cathepsins and the cutting edge of cancer invasionQ34605340
High levels of nuclear heat-shock factor 1 (HSF1) are associated with poor prognosis in breast cancerQ35546764
The role of Cathepsin S as a marker of prognosis and predictor of chemotherapy benefit in adjuvant CRC: a pilot studyQ35623073
Targeting inflammatory pathways for prevention and therapy of cancer: short-term friend, long-term foe.Q37369658
Deciphering the role of PI3K/Akt/mTOR pathway in breast cancer biology and pathogenesisQ37813282
Blockade of CD47-mediated cathepsin S/protease-activated receptor 2 signaling provides a therapeutic target for hepatocellular carcinoma.Q39024382
Silencing cathepsin S gene expression inhibits growth, invasion and angiogenesis of human hepatocellular carcinoma in vitro.Q39314730
miR-520c and miR-373 upregulate MMP9 expression by targeting mTOR and SIRT1, and activate the Ras/Raf/MEK/Erk signaling pathway and NF-κB factor in human fibrosarcoma cellsQ39427500
PI3K/Akt-dependent transcriptional regulation and activation of BMP-2-Smad signaling by NF-kappaB in metastatic prostate cancer cellsQ39926569
High HSP90 expression is associated with decreased survival in breast cancerQ40149432
Phosphatidylinositol-3-OH kinase or RAS pathway mutations in human breast cancer cell linesQ40168416
Antibody-mediated inhibition of cathepsin S blocks colorectal tumor invasion and angiogenesisQ43269533
Fibronectin expression in carcinoma cells correlates with tumor aggressiveness and poor clinical outcome in patients with invasive breast cancer.Q43728820
Association between serum cathepsin S and mortality in older adultsQ44578257
Cathepsin S controls angiogenesis and tumor growth via matrix-derived angiogenic factors.Q46859366
Binding of chondroitin 4-sulfate to cathepsin S regulates its enzymatic activityQ47724503
Cathepsin S expression: An independent prognostic factor in glioblastoma tumours--A pilot studyQ48610874
Molecular fingerprinting and autocrine growth regulation of endothelial cells in a murine model of hepatocellular carcinoma.Q53350643
Secretory leucocyte protease inhibitor inhibits interferon-gamma-induced cathepsin S expression.Q53526931
Androgen receptor expression predicts decreased survival in early stage triple-negative breast cancer.Q54328011
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)29-40
P577publication date2016-10-27
P1433published inBreast Cancer Research and TreatmentQ326085
P1476titleUp-regulation of cathepsin S expression by HSP90 and 5-HT7 receptor-dependent serotonin signaling correlates with triple negativity of human breast cancer
P478volume161

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cites work (P2860)
Q906364375-HT7 Receptor Contributes to Proliferation, Migration and Invasion in NSCLC Cells
Q92187139A Novel Role for Cathepsin S as a Potential Biomarker in Triple Negative Breast Cancer
Q58763841Down-regulation of cathepsin S and matrix metalloproteinase-9 via Src, a non-receptor tyrosine kinase, suppresses triple-negative breast cancer growth and metastasis
Q99406536Heat shock protein 90α in thymic epithelial tumors and non-thymomatous myasthenia gravis
Q88636947Integrated bioinformatics analysis reveals that the expression of cathepsin S is associated with lymph node metastasis and poor prognosis in papillary thyroid cancer

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