An alien divalent ion reveals a major role for Ca²⁺ buffering in controlling slow transmitter release.

scientific article published in September 2014

An alien divalent ion reveals a major role for Ca²⁺ buffering in controlling slow transmitter release. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1523/JNEUROSCI.1990-14.2014
P932PMC publication ID6705322
P698PubMed publication ID25232102

P50authorOlexiy KochubeyQ41046891
P2093author name stringNorbert Babai
Ralf Schneggenburger
Daniel Keller
P2860cites workSr2+ binding to the Ca2+ binding site of the synaptotagmin 1 C2B domain triggers fast exocytosis without stimulating SNARE interactionsQ24338669
A dual-Ca2+-sensor model for neurotransmitter release in a central synapseQ26269875
A new generation of Ca2+ indicators with greatly improved fluorescence propertiesQ27860793
Synaptotagmin I functions as a calcium regulator of release probabilityQ28204147
Synaptotagmin-2 is essential for survival and contributes to Ca2+ triggering of neurotransmitter release in central and neuromuscular synapsesQ28280944
Chelation of divalent cations by ATP, studied by titration calorimetryQ28321274
Synaptotagmin I: a major Ca2+ sensor for transmitter release at a central synapseQ28587672
SNARE protein recycling by αSNAP and βSNAP supports synaptic vesicle primingQ28589671
Asynchronous transmitter release from cholecystokinin-containing inhibitory interneurons is widespread and target-cell independentQ30490991
Intraterminal Ca(2+) and spontaneous transmitter release at the frog neuromuscular junctionQ31816915
Combining deconvolution and noise analysis for the estimation of transmitter release rates at the calyx of held.Q31840785
Usefulness and limitations of linear approximations to the understanding of Ca++ signalsQ33544680
FAST MONTE CARLO SIMULATION METHODS FOR BIOLOGICAL REACTION-DIFFUSION SYSTEMS IN SOLUTION AND ON SURFACES.Q33641314
Detection of spontaneous synaptic events with an optimally scaled templateQ33907017
Strontium as a Substitute for Calcium in the Process of Transmitter Release at the Neuromuscular JunctionQ34024764
Presynaptic strontium dynamics and synaptic transmissionQ34170222
Calcium dynamics associated with a single action potential in a CNS presynaptic terminalQ34424904
Inhibitory regulation of electrically coupled neurons in the inferior olive is mediated by asynchronous release of GABAQ34983523
Two components of transmitter release at a central synapseQ36013914
Action potential evoked transmitter release in central synapses: insights from the developing calyx of HeldQ37638786
Calcium gradients and buffers in bovine chromaffin cellsQ39227699
Co-operative action a calcium ions in transmitter release at the neuromuscular junctionQ41528052
Allosteric modulation of the presynaptic Ca2+ sensor for vesicle fusion.Q42478821
Calmodulin mediates rapid recruitment of fast-releasing synaptic vesicles at a calyx-type synapseQ43832090
Calcium secretion coupling at calyx of Held governed by nonuniform channel-vesicle topography.Q43906979
Development and application of caged calciumQ44351978
Intraterminal Ca2+ concentration and asynchronous transmitter release at single GABAergic boutons in rat collicular culturesQ44364051
Developmental regulation of the intracellular Ca2+ sensitivity of vesicle fusion and Ca2+-secretion coupling at the rat calyx of HeldQ45042077
Dual roles of the C2B domain of synaptotagmin I in synchronizing Ca2+-dependent neurotransmitter release.Q45084937
Asynchronous GABA release generates long-lasting inhibition at a hippocampal interneuron-principal neuron synapseQ46699474
Released fraction and total size of a pool of immediately available transmitter quanta at a calyx synapseQ47261826
High-frequency firing helps replenish the readily releasable pool of synaptic vesiclesQ47741527
Parvalbumin is a mobile presynaptic Ca2+ buffer in the calyx of Held that accelerates the decay of Ca2+ and short-term facilitation.Q48257729
Sr2+-dependent asynchronous evoked transmission at rat striatal inhibitory synapses in vitroQ48329805
Calcium current during a single action potential in a large presynaptic terminal of the rat brainstemQ48524790
Presynaptic depression at a calyx synapse: the small contribution of metabotropic glutamate receptors.Q48617265
Studies of calcium channels in rat clonal pituitary cells with patch electrode voltage clampQ48892721
Synaptotagmin increases the dynamic range of synapses by driving Ca²+-evoked release and by clamping a near-linear remaining Ca²+ sensor.Q50526332
A quantitative measurement of the dependence of short-term synaptic enhancement on presynaptic residual calcium.Q51651514
Synaptotagmin I functions as a calcium sensor to synchronize neurotransmitter release.Q52009038
Mobile and immobile calcium buffers in bovine adrenal chromaffin cells.Q52391238
The C(2)B Ca(2+)-binding motif of synaptotagmin is required for synaptic transmission in vivo.Q52597582
Linearized buffered Ca2+ diffusion in microdomains and its implications for calculation of [Ca2+] at the mouth of a calcium channel.Q53964843
Localization of calcium signals by a mobile calcium buffer in frog saccular hair cellsQ72418257
Simultaneous measurement of intracellular Ca2+ and asynchronous transmitter release from the same crayfish boutonQ73435887
Probing fundamental aspects of synaptic transmission with strontiumQ73870623
Ion selectivities of the Ca(2+) sensors for exocytosis in rat phaeochromocytoma cellsQ74034513
Calcium sensitivity of glutamate release in a calyx-type terminalQ74152482
Intracellular calcium dependence of transmitter release rates at a fast central synapseQ74265558
A mechanism intrinsic to the vesicle fusion machinery determines fast and slow transmitter release at a large CNS synapseQ80005913
Two Ca(2+)-dependent steps controlling synaptic vesicle fusion and replenishment at the cerebellar basket cell terminalQ80646761
P433issue38
P407language of work or nameEnglishQ1860
P304page(s)12622-12635
P577publication date2014-09-01
P1433published inJournal of NeuroscienceQ1709864
P1476titleAn alien divalent ion reveals a major role for Ca²⁺ buffering in controlling slow transmitter release
P478volume34

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cites work (P2860)
Q35995925An Engineered Metal Sensor Tunes the Kinetics of Synaptic Transmission.
Q35624301An Exclusion Zone for Ca2+ Channels around Docked Vesicles Explains Release Control by Multiple Channels at a CNS Synapse
Q58612189Arginine-rich cell-penetrating peptides induce membrane multilamellarity and subsequently enter via formation of a fusion pore
Q38445469Ca2+ channel to synaptic vesicle distance accounts for the readily releasable pool kinetics at a functionally mature auditory synapse.
Q37041611Desensitization-resistant and -sensitive GPCR-mediated inhibition of GABA release occurs by Ca2+-dependent and -independent mechanisms at a hypothalamic synapse
Q39106289Dynamics of volume-averaged intracellular Ca2+ in a rat CNS nerve terminal during single and repetitive voltage-clamp depolarizations.
Q26766019Molecular Machines Regulating the Release Probability of Synaptic Vesicles at the Active Zone
Q38537229Molecular mechanisms governing Ca(2+) regulation of evoked and spontaneous release
Q39633014Parallel processing of afferent olfactory sensory information
Q35740458Reduced endogenous Ca2+ buffering speeds active zone Ca2+ signaling
Q48133011Sr2+ has low efficiency in regulating spontaneous release at the Calyx of Held synapses.
Q48445725Substitution of extracellular Ca2+ by Sr2+ prolongs inspiratory burst in pre-Bötzinger complex inspiratory neurons.
Q88204780Synaptotagmin 7 Mediates Both Facilitation and Asynchronous Release at Granule Cell Synapses

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