Action potential evoked transmitter release in central synapses: insights from the developing calyx of Held

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Action potential evoked transmitter release in central synapses: insights from the developing calyx of Held is …
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scholarly articleQ13442814
review articleQ7318358

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P6179Dimensions Publication ID1041247921
P356DOI10.1186/1756-6606-2-36
P932PMC publication ID2794261
P698PubMed publication ID19939269
P5875ResearchGate publication ID40032491

P2093author name stringYi-Mei Yang
Lu-Yang Wang
Michael J Fedchyshyn
P2860cites workRelationship between presynaptic calcium current and postsynaptic potential in squid giant synapseQ24536100
Transmission by presynaptic spike-like depolarization in the squid giant synapseQ24632510
Microdomains of high calcium concentration in a presynaptic terminalQ28182130
Control of synaptic strength and timing by the release-site Ca2+ signalQ33212596
Synaptic mechanisms for coding timing in auditory neuronsQ33547248
The action potential in mammalian central neuronsQ34004305
Time course of transmitter release calculated from simulations of a calcium diffusion modelQ34088480
Three-dimensional reconstruction of a calyx of Held and its postsynaptic principal neuron in the medial nucleus of the trapezoid body.Q34165304
Single calcium channels and acetylcholine release at a presynaptic nerve terminalQ34347240
Timing of neurotransmission at fast synapses in the mammalian brainQ34406384
Short-term plasticity at the calyx of HeldQ34514471
Presynaptic Na+ channels: locus, development, and recovery from inactivation at a high-fidelity synapseQ35878912
Are the presynaptic membrane particles the calcium channels?Q36380701
Mechanism of calcium current modulation underlying presynaptic facilitation and behavioral sensitization in AplysiaQ36417003
R-type Ca2+ currents evoke transmitter release at a rat central synapseQ36480033
The calcium signal for transmitter secretion from presynaptic nerve terminals.Q36534579
The calyx of Held.Q36560428
The sequence of events that underlie quantal transmission at central glutamatergic synapsesQ36885427
Multiple roles of calcium ions in the regulation of neurotransmitter releaseQ37279408
Distinct roles of Kv1 and Kv3 potassium channels at the calyx of Held presynaptic terminal.Q39750979
Presynaptic Ca2+ buffers control the strength of a fast post-tetanic hyperpolarization mediated by the alpha3 Na(+)/K(+)-ATPase.Q39752081
Synaptic vesicle pool size, release probability and synaptic depression are sensitive to Ca2+ buffering capacity in the developing rat calyx of HeldQ40809166
Effect of changes in action potential shape on calcium currents and transmitter release in a calyx-type synapse of the rat auditory brainstemQ40856259
The inhibitory effects of omega-conotoxins on Ca channels and synapsesQ41270818
Co-operative action a calcium ions in transmitter release at the neuromuscular junctionQ41528052
Vesicle pools and Ca2+ microdomains: new tools for understanding their roles in neurotransmitter releaseQ41737185
Timing and efficacy of Ca2+ channel activation in hippocampal mossy fiber boutons.Q42690905
Synaptic vesicle endocytosis at a CNS nerve terminal: faster kinetics at physiological temperatures and increased endocytotic capacity during maturation.Q50455129
Direct patch recording from identified presynaptic terminals mediating glutamatergic EPSCs in the rat CNS, in vitro.Q51625037
Developmental changes in calcium channel types mediating central synaptic transmission.Q52171906
Linearized buffered Ca2+ diffusion in microdomains and its implications for calculation of [Ca2+] at the mouth of a calcium channel.Q53964843
Two modes of fusion pore opening revealed by cell-attached recordings at a synapse.Q55042647
Synaptotagmin has an essential function in synaptic vesicle positioning for synchronous release in addition to its role as a calcium sensorQ64375154
Pre- and postsynaptic whole-cell recordings in the medial nucleus of the trapezoid body of the ratQ71490972
Calcium control of transmitter release at a cerebellar synapseQ71712437
Localization of calcium signals by a mobile calcium buffer in frog saccular hair cellsQ72418257
Calcium sensitivity of glutamate release in a calyx-type terminalQ74152482
Intracellular calcium dependence of transmitter release rates at a fast central synapseQ74265558
Local routes revisited: the space and time dependence of the Ca2+ signal for phasic transmitter release at the rat calyx of HeldQ78872717
The role of physiological afferent nerve activity during in vivo maturation of the calyx of Held synapseQ79775834
A unified model of presynaptic release site gating by calcium channel domainsQ81283466
Size of supramolecular SNARE complex: membrane-directed self-assemblyQ43242382
Presynaptic calcium and serotonin-mediated enhancement of transmitter release at crayfish neuromuscular junctionQ43418645
Fast kinetics of exocytosis revealed by simultaneous measurements of presynaptic capacitance and postsynaptic currents at a central synapseQ43601414
Calcium secretion coupling at calyx of Held governed by nonuniform channel-vesicle topography.Q43906979
Developmental profiles of glutamate receptors and synaptic transmission at a single synapse in the mouse auditory brainstemQ43977803
Optimizing synaptic architecture and efficiency for high-frequency transmissionQ44258616
Isoflurane inhibits transmitter release and the presynaptic action potentialQ44860918
Developmental regulation of the intracellular Ca2+ sensitivity of vesicle fusion and Ca2+-secretion coupling at the rat calyx of HeldQ45042077
Alien intracellular calcium chelators attenuate neurotransmitter release at the squid giant synapseQ45328670
Regulation of transmitter release at the squid giant synapse by presynaptic delayed rectifier potassium current.Q45965973
Synaptic vesicles in mature calyx of Held synapses sense higher nanodomain calcium concentrations during action potential-evoked glutamate releaseQ46178156
Developmental transformation of the release modality at the calyx of Held synapse.Q46448188
Fine-tuning an auditory synapse for speed and fidelity: developmental changes in presynaptic waveform, EPSC kinetics, and synaptic plasticity.Q46689899
Pharmacological identification of two types of presynaptic voltage-dependent calcium channels at CA3-CA1 synapses of the hippocampus.Q46717183
Nanodomain coupling between Ca2+ channels and Ca2+ sensors promotes fast and efficient transmitter release at a cortical GABAergic synapseQ46730437
High-frequency firing helps replenish the readily releasable pool of synaptic vesiclesQ47741527
Parvalbumin is a mobile presynaptic Ca2+ buffer in the calyx of Held that accelerates the decay of Ca2+ and short-term facilitation.Q48257729
Presynaptic rat Kv1.2 channels suppress synaptic terminal hyperexcitability following action potential invasionQ48294517
Calcium channel types with distinct presynaptic localization couple differentially to transmitter release in single calyx-type synapses.Q48310664
Subcellular localization of the voltage-dependent potassium channel Kv3.1b in postnatal and adult rat medial nucleus of the trapezoid body.Q48317618
Amplitude and kinetics of action potential-evoked Ca2+ current and its efficacy in triggering transmitter release at the developing calyx of Held synapse.Q48523206
Calcium current during a single action potential in a large presynaptic terminal of the rat brainstemQ48524790
Control of neurotransmitter release by presynaptic waveform at the granule cell to Purkinje cell synapse.Q48707034
Presynaptic calcium current modulation by a metabotropic glutamate receptor.Q48887621
Calcium influx and transmitter release in a fast CNS synapseQ48892633
Dynamic control of presynaptic Ca(2+) inflow by fast-inactivating K(+) channels in hippocampal mossy fiber boutonsQ49063169
P275copyright licenseCreative Commons Attribution 2.0 GenericQ19125117
P6216copyright statuscopyrightedQ50423863
P921main subjectnervous systemQ9404
mechanism of actionQ3271540
P304page(s)36
P577publication date2009-11-25
P1433published inMolecular BrainQ6895938
P1476titleAction potential evoked transmitter release in central synapses: insights from the developing calyx of Held
P478volume2

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Q64096087Timing constraints of action potential evoked Ca current and transmitter release at a central nerve terminal
Q30446050Tuning and timing in mammalian type I hair cells and calyceal synapses
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Q28272276Upregulation of transmitter release probability improves a conversion of synaptic analogue signals into neuronal digital spikes
Q88123788Variations in Ca2+ Influx Can Alter Chelator-Based Estimates of Ca2+ Channel-Synaptic Vesicle Coupling Distance

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