| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/S1074-7613(02)00418-1 |
| P698 | PubMed publication ID | 12387741 |
| P50 | author | Peter Pfeffer | Q42807563 |
| Meinrad Busslinger | Q42137651 | ||
| P2093 | author name string | Michael Schebesta | |
| P2860 | cites work | Commitment to the B-lymphoid lineage depends on the transcription factor Pax5 | Q22010683 |
| An essential role for BLNK in human B cell development | Q22010875 | ||
| Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk | Q24303475 | ||
| Phosphorylation of platelet pleckstrin activates inositol polyphosphate 5-phosphatase I | Q24313757 | ||
| Pleckstrin inhibits phosphoinositide hydrolysis initiated by G-protein-coupled and growth factor receptors. A role for pleckstrin's PH domains | Q24322201 | ||
| BLNK: a central linker protein in B cell activation | Q24322718 | ||
| The promoter of the CD19 gene is a target for the B-cell-specific transcription factor BSAP | Q24630244 | ||
| SLP-65: a new signaling component in B lymphocytes which requires expression of the antigen receptor for phosphorylation | Q24645697 | ||
| Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases | Q27626747 | ||
| Precursor B cell receptor-dependent B cell proliferation and differentiation does not require the bone marrow or fetal liver environment | Q42947341 | ||
| Early function of Pax5 (BSAP) before the pre-B cell receptor stage of B lymphopoiesis | Q42972627 | ||
| Essential functions of Pax5 (BSAP) in pro-B cell development: difference between fetal and adult B lymphopoiesis and reduced V-to-DJ recombination at the IgH locus. | Q52196159 | ||
| IL-2 receptor alpha chain (CD25, TAC) expression defines a crucial stage in pre-B cell development | Q71659842 | ||
| A conserved degradation signal regulates RAG-2 accumulation during cell division and links V(D)J recombination to the cell cycle | Q71952814 | ||
| NF-kappa B activation by the pre-T cell receptor serves as a selective survival signal in T lymphocyte development | Q73291757 | ||
| B cell development and activation defects resulting in xid-like immunodeficiency in BLNK/SLP-65-deficient mice | Q73505483 | ||
| Molecular cloning and expression of mouse and human cDNAs encoding heparan sulfate D-glucosaminyl 3-O-sulfotransferase | Q28114813 | ||
| BLNK required for coupling Syk to PLC gamma 2 and Rac1-JNK in B cells | Q28137612 | ||
| Engagement of the human pre-B cell receptor generates a lipid raft-dependent calcium signaling complex | Q28138324 | ||
| Requirement for B cell linker protein (BLNK) in B cell development | Q28139413 | ||
| Abnormal development and function of B lymphocytes in mice deficient for the signaling adaptor protein SLP-65 | Q28139860 | ||
| Analysis of C-MYC function in normal cells via conditional gene-targeted mutation | Q28143481 | ||
| RAIDD is a new 'death' adaptor molecule | Q28300622 | ||
| Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism | Q28585177 | ||
| Distinct membrane and cytosolic forms of inositol polyphosphate 5-phosphatase II. Efficient membrane localization requires two discrete domains | Q28586743 | ||
| Syk tyrosine kinase required for mouse viability and B-cell development | Q28586985 | ||
| Cbl suppresses B cell receptor-mediated phospholipase C (PLC)-gamma2 activation by regulating B cell linker protein-PLC-gamma2 binding | Q30840928 | ||
| Regulation of the helix-loop-helix proteins, E2A and Id3, by the Ras-ERK MAPK cascade | Q31929689 | ||
| BLNK: connecting Syk and Btk to calcium signals | Q33830846 | ||
| Introduction of a mu immunoglobulin gene into the mouse germ line: specific expression in lymphoid cells and synthesis of functional antibody | Q34245413 | ||
| Phosphodiesterase profile of human B lymphocytes from normal and atopic donors and the effects of PDE inhibition on B cell proliferation | Q35027305 | ||
| The B cell-restricted adaptor BASH is required for normal development and antigen receptor-mediated activation of B cells | Q35081009 | ||
| The regulated expression of B lineage associated genes during B cell differentiation in bone marrow and fetal liver | Q36362209 | ||
| The cytoplasmic domains of immunoglobulin (Ig) alpha and Ig beta can independently induce the precursor B cell transition and allelic exclusion | Q36365409 | ||
| Adapter proteins SLP-76 and BLNK both are expressed by murine macrophages and are linked to signaling via Fcgamma receptors I and II/III | Q37115143 | ||
| DNA-binding and transactivation properties of Pax-6: three amino acids in the paired domain are responsible for the different sequence recognition of Pax-6 and BSAP (Pax-5). | Q38295887 | ||
| Regulation of Cre recombinase activity by mutated estrogen receptor ligand-binding domains | Q38343320 | ||
| Impaired immune responses and B-cell proliferation in mice lacking the Id3 gene | Q39447043 | ||
| SSeCKS, a major protein kinase C substrate with tumor suppressor activity, regulates G(1)-->S progression by controlling the expression and cellular compartmentalization of cyclin D. | Q39455728 | ||
| Different initiation of pre-TCR and gammadeltaTCR signalling | Q40859942 | ||
| Clonal selection and learning in the antibody system | Q41002744 | ||
| Thymocyte development in the absence of pre-T cell receptor extracellular immunoglobulin domains | Q41041097 | ||
| Down-regulation of RAG1 and RAG2 gene expression in PreB cells after functional immunoglobulin heavy chain rearrangement | Q41278530 | ||
| Internalization of B cell and pre-B cell receptors is regulated by tyrosine kinase and phosphatase activities. | Q41289620 | ||
| Precursor B cells of mouse bone marrow express two different complexes with the surrogate light chain on the surface | Q41371618 | ||
| The c-kit-encoded tyrosine kinase regulates the proliferation of early pre-B cells | Q42467234 | ||
| Identification of BSAP (Pax-5) target genes in early B-cell development by loss- and gain-of-function experiments | Q42642886 | ||
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 473-485 | |
| P577 | publication date | 2002-10-01 | |
| P1433 | published in | Immunity | Q6005457 |
| P1476 | title | Control of pre-BCR signaling by Pax5-dependent activation of the BLNK gene | |
| P478 | volume | 17 |
| Q39285321 | A novel mechanism for the autonomous termination of pre-B cell receptor expression via induction of lysosome-associated protein transmembrane 5. |
| Q39793982 | A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation |
| Q34740831 | Activation of the early B-cell-specific mb-1 (Ig-alpha) gene by Pax-5 is dependent on an unmethylated Ets binding site. |
| Q34044904 | Activation-induced cytidine deaminase (AID)-associated multigene signature to assess impact of AID in etiology of diseases with inflammatory component |
| Q36744575 | B Cell Linker Protein (BLNK) Is a Selective Target of Repression by PAX5-PML Protein in the Differentiation Block That Leads to the Development of Acute Lymphoblastic Leukemia |
| Q35945154 | B cell activator PAX5 promotes lymphomagenesis through stimulation of B cell receptor signaling |
| Q35591032 | B-cell antigen-receptor signalling in lymphocyte development |
| Q33902336 | BCL6 is critical for the development of a diverse primary B cell repertoire |
| Q41871315 | Bruton's tyrosine kinase cooperates with the B cell linker protein SLP-65 as a tumor suppressor in Pre-B cells. |
| Q79988998 | Btk and phospholipase C gamma 2 can function independently during B cell development |
| Q35693333 | CCR5 blockade is well tolerated and induces changes in the tissue distribution of CCR5+ and CD25+ T cells in healthy, SIV-uninfected rhesus macaques |
| Q52110892 | Checks and balances on developing B cells. |
| Q73588967 | Contribution of BCAP to maintenance of mature B cells through c-Rel |
| Q24673653 | Distinct promoters mediate the regulation of Ebf1 gene expression by interleukin-7 and Pax5 |
| Q37377456 | Distinct roles for E12 and E47 in B cell specification and the sequential rearrangement of immunoglobulin light chain loci |
| Q73555532 | Distinct signaling requirements for Dmu selection, IgH allelic exclusion, pre-B cell transition, and tumor suppression in B cell progenitors |
| Q36499759 | Dual role of the adaptor protein SLP-65: organizer of signal transduction and tumor suppressor of pre-B cell leukemia. |
| Q39991478 | Efficient retroviral transduction of human B-lymphoid and myeloid progenitors: marked inhibition of their growth by the Pax5 transgene |
| Q36942506 | Fate decisions regulating bone marrow and peripheral B lymphocyte development |
| Q41182606 | FoxO1 induces Ikaros splicing to promote immunoglobulin gene recombination |
| Q36292892 | Helix-loop-helix proteins and lymphocyte development |
| Q27001749 | Heparan sulfate proteoglycans in the control of B cell development and the pathogenesis of multiple myeloma |
| Q33588862 | Hodgkin lymphoma: an update on its biology with new insights into classification |
| Q37679476 | Impaired B lymphopoiesis in old age: a role for inflammatory B cells? |
| Q37670076 | Increased BCR responsiveness in B cells from patients with chronic GVHD. |
| Q101403195 | Inhibition of inflammatory signaling in Pax5 mutant cells mitigates B-cell leukemogenesis |
| Q36472229 | Integrated signaling in developing lymphocytes: the role of DNA damage responses |
| Q39657462 | Interleukin-7-induced Stat-5 acts in synergy with Flt-3 signaling to stimulate expansion of hematopoietic progenitor cells. |
| Q73836551 | LAT links the pre-BCR to calcium signaling |
| Q36228399 | Lineage specification and plasticity in CD19- early B cell precursors |
| Q38398480 | Locus 'decontraction' and centromeric recruitment contribute to allelic exclusion of the immunoglobulin heavy-chain gene |
| Q24317920 | Long-term cultured E2A-deficient hematopoietic progenitor cells are pluripotent |
| Q36846366 | Lymphocyte development: integration of DNA damage response signaling |
| Q33473001 | MLL rearrangements in pediatric acute lymphoblastic and myeloblastic leukemias: MLL specific and lineage specific signatures |
| Q39649757 | Overexpression of PAX5 induces apoptosis in multiple myeloma cells |
| Q35006755 | PAX5 activates the transcription of the human telomerase reverse transcriptase gene in B cells |
| Q39610277 | PAX5-PML acts as a dual dominant-negative form of both PAX5 and PML. |
| Q48191005 | PI3K induces B-cell development and regulates B cell identity |
| Q41945079 | Pax5 induces V-to-DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene |
| Q33789597 | Pax5 loss imposes a reversible differentiation block in B-progenitor acute lymphoblastic leukemia |
| Q48269882 | Pax5 promotes B lymphopoiesis and blocks T cell development by repressing Notch1. |
| Q36570655 | Pax5--a critical inhibitor of plasma cell fate |
| Q36794303 | Pax5: the guardian of B cell identity and function |
| Q33346071 | Perplexing Pax: from puzzle to paradigm. |
| Q39913649 | PhenomeExpress: a refined network analysis of expression datasets by inclusion of known disease phenotypes |
| Q54637388 | Pre-B-cell leukemias in Btk/Slp65-deficient mice arise independently of ongoing V(D)J recombination activity |
| Q35723998 | Rationale for targeting the pre-B-cell receptor signaling pathway in acute lymphoblastic leukemia |
| Q36399448 | Receptor editing and marginal zone B cell development are regulated by the helix-loop-helix protein, E2A |
| Q35084267 | Regulatory coding of lymphoid lineage choice by hematopoietic transcription factors |
| Q42175565 | Role of STAT5 in controlling cell survival and immunoglobulin gene recombination during pro-B cell development |
| Q35012081 | Roles of EBF and Pax-5 in B lineage commitment and development. |
| Q36978595 | The B-cell-specific transcription factor and master regulator Pax5 promotes Epstein-Barr virus latency by negatively regulating the viral immediate early protein BZLF1. |
| Q36403907 | The BCR-ABL1 kinase bypasses selection for the expression of a pre-B cell receptor in pre-B acute lymphoblastic leukemia cells |
| Q79427919 | The Ig-alpha ITAM is required for efficient differentiation but not proliferation of pre-B cells |
| Q34166538 | The PAX5 gene is frequently rearranged in BCR-ABL1-positive acute lymphoblastic leukemia but is not associated with outcome. A report on behalf of the GIMEMA Acute Leukemia Working Party |
| Q89120229 | The endoplasmic reticulum-resident E3 ubiquitin ligase Hrd1 controls a critical checkpoint in B cell development in mice |
| Q39640399 | The reduced and altered activities of PAX5 are linked to the protein–protein interaction motif (coiled-coil domain) of the PAX5–PML fusion protein in t(9;15)-associated acute lymphocytic leukemia |
| Q36999672 | The regulation of the B-cell gene expression programme by Pax5. |
| Q35555992 | Transcription factors controlling the beginning and end of B-cell differentiation |
| Q37279924 | Transcriptional regulation of early B cell development |
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