| scholarly article | Q13442814 |
| P50 | author | Alexander G. Alexandro | Q60311209 |
| Esther Shohami | Q60311212 | ||
| Ronit Pinkas-Kramarski | Q30111759 | ||
| Shlomit Erlich | Q60311207 | ||
| P2093 | author name string | Alexandrovich A | |
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | sirolimus | Q32089 |
| neuroscience | Q207011 | ||
| P304 | page(s) | 86-93 | |
| P577 | publication date | 2007-01-01 | |
| 2007-01-31 | |||
| P1433 | published in | Neurobiology of Disease | Q15716606 |
| P1476 | title | Rapamycin is a neuroprotective treatment for traumatic brain injury | |
| P478 | volume | 26 |
| Q36379761 | A Critical Kinase Cascade in Neurological Disorders: PI 3-K, Akt, and mTOR. |
| Q37419785 | A critical review of mTOR inhibitors and epilepsy: from basic science to clinical trials |
| Q28395005 | Abnormalities in Diffusional Kurtosis Metrics Related to Head Impact Exposure in a Season of High School Varsity Football |
| Q35782367 | Accumulation of p62 in degenerated spinal cord under chronic mechanical compression: functional analysis of p62 and autophagy in hypoxic neuronal cells |
| Q50231758 | Acute spinal cord injury could cause activation of autophagy in dorsal root ganglia |
| Q37377107 | Akt signals through the mammalian target of rapamycin pathway to regulate CNS myelination. |
| Q37434629 | All-you-can-eat: autophagy in neurodegeneration and neuroprotection. |
| Q47272029 | Amyloid β-Derived Diffusible Ligands (ADDLs) Induce Abnormal Autophagy Associated with Aβ Aggregation Degree |
| Q33972087 | Astrocyte activation is suppressed in both normal and injured brain by FGF signaling |
| Q48745538 | Autophagic neuron death |
| Q48387954 | Autophagy Biomarkers Beclin 1 and p62 are Increased in Cerebrospinal Fluid after Traumatic Brain Injury |
| Q37138196 | Autophagy alleviates neurodegeneration caused by mild impairment of oxidative metabolism |
| Q38247994 | Autophagy and neurodegenerative disorders |
| Q91801594 | Autophagy in Neurotrauma: Good, Bad, or Dysregulated |
| Q55228013 | Autophagy in Traumatic Brain Injury: A New Target for Therapeutic Intervention. |
| Q38852246 | Autophagy in acute brain injury |
| Q34612934 | Autophagy in acute brain injury: feast, famine, or folly? |
| Q85172545 | Autophagy in myocardium of murine hearts subjected to ischemia followed by reperfusion |
| Q91542980 | Autophagy induction in the treatment of Alzheimer's disease |
| Q33337389 | Autophagy is activated and might protect neurons from degeneration after traumatic brain injury |
| Q46759661 | Autophagy reduces neuronal damage and promotes locomotor recovery via inhibition of apoptosis after spinal cord injury in rats |
| Q37990880 | Axonal degeneration as a therapeutic target in the CNS. |
| Q61449882 | Baicalin Protects Mice Brain From Apoptosis in Traumatic Brain Injury Model Through Activation of Autophagy |
| Q54369231 | Beclin-1-mediated autophagy protects spinal cord neurons against mechanical injury-induced apoptosis. |
| Q36489622 | Beneficial Effects of Early mTORC1 Inhibition after Traumatic Brain Injury. |
| Q40183907 | Blood-brain barrier leakage after status epilepticus in rapamycin-treated rats II: Potential mechanisms. |
| Q33829410 | CD38 facilitates recovery from traumatic brain injury |
| Q33687969 | Chondrocyte autophagy is stimulated by HIF-1 dependent AMPK activation and mTOR suppression |
| Q40860354 | Combination therapy targeting Akt and mammalian target of rapamycin improves functional outcome after controlled cortical impact in mice |
| Q92441593 | Control of Inflammation by Calorie Restriction Mimetics: On the Crossroad of Autophagy and Mitochondria |
| Q46511515 | Demyelinating sensorimotor polyneuropathy associated with the use of sirolimus: a case report |
| Q35242749 | Detrusor myocyte autophagy protects the bladder function via inhibiting the inflammation in cyclophosphamide-induced cystitis in rats. |
| Q33805859 | Developing Antiepileptogenic Drugs for Acquired Epilepsy: Targeting the Mammalian Target of Rapamycin (mTOR) Pathway |
| Q90049756 | Different Approaches to Modulation of Microglia Phenotypes After Spinal Cord Injury |
| Q37180223 | Dysfunction of the mTOR pathway is a risk factor for Alzheimer's disease. |
| Q38946303 | ER stress and impaired autophagy flux in neuronal degeneration and brain injury. |
| Q90277782 | Effect of autophagy on allodynia, hyperalgesia and astrocyte activation in a rat model of neuropathic pain |
| Q57175060 | Effects of rapamycin and curcumin on inflammation and oxidative stress in vitro and in vivo - in search of potential anti-epileptogenic strategies for temporal lobe epilepsy |
| Q33937774 | Evaluation of autophagy using mouse models of brain injury |
| Q58727047 | Expression profile of plasma microRNAs and their roles in diagnosis of mild to severe traumatic brain injury |
| Q46451320 | FGF2 Attenuates Neural Cell Death via Suppressing Autophagy after Rat Mild Traumatic Brain Injury. |
| Q28243647 | Fighting neurodegeneration with rapamycin: mechanistic insights |
| Q27024547 | Finding a better drug for epilepsy: the mTOR pathway as an antiepileptogenic target |
| Q35014198 | Frontier of epilepsy research - mTOR signaling pathway |
| Q38390761 | Function and Mechanisms of Autophagy in Brain and Spinal Cord Trauma |
| Q34919457 | Genetic activation of mTORC1 signaling worsens neurocognitive outcome after traumatic brain injury |
| Q21996341 | Guidelines for the use and interpretation of assays for monitoring autophagy |
| Q23757358 | Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes |
| Q42914489 | Heat Stroke Induces Autophagy as a Protection Mechanism Against Neurodegeneration in the Brain |
| Q26866001 | How longevity research can lead to therapies for Alzheimer's disease: The rapamycin story |
| Q41072206 | Hydrogen Sulfide Inhibits Autophagic Neuronal Cell Death by Reducing Oxidative Stress in Spinal Cord Ischemia Reperfusion Injury. |
| Q84165333 | Immunosuppressant cytoprotection correlates with HMGB1 suppression in primary astrocyte cultures exposed to combined oxygen-glucose deprivation |
| Q49959235 | Impaired autophagic flux is associated with the severity of trauma and the role of A2AR in brain cells after traumatic brain injury |
| Q41611849 | Impaired autophagy flux is associated with neuronal cell death after traumatic brain injury |
| Q89218723 | In search of antiepileptogenic treatments for post-traumatic epilepsy |
| Q33547453 | Induction of autophagy by cystatin C: a mechanism that protects murine primary cortical neurons and neuronal cell lines |
| Q51025755 | Induction of neuronal mitophagy in acute spinal cord injury in rats. |
| Q28476525 | Influence of stochastic gene expression on the cell survival rheostat after traumatic brain injury |
| Q50047528 | Inhibition of mammalian target of rapamycin complex 1 signaling by n-3 polyunsaturated fatty acids promotes locomotor recovery after spinal cord injury |
| Q37684935 | Inhibition of mammalian target of rapamycin improves neurobehavioral deficit and modulates immune response after intracerebral hemorrhage in rat. |
| Q48501239 | Inhibition of mammalian target of rapamycin reduces epileptogenesis and blood-brain barrier leakage but not microglia activation |
| Q48042335 | Ketamine Exhibits Different Neuroanatomical Profile After Mammalian Target of Rapamycin Inhibition in the Prefrontal Cortex: the Role of Inflammation and Oxidative Stress |
| Q64231716 | Killing Two Angry Birds with One Stone: Autophagy Activation by Inhibiting Calpains in Neurodegenerative Diseases and Beyond |
| Q57454960 | Lithium promotes recovery of neurological function after spinal cord injury by inducing autophagy |
| Q35853337 | Lithium protects dopaminergic cells from rotenone toxicity via autophagy enhancement |
| Q34498303 | Mammalian target of rapamycin (mTOR) inhibition as a potential antiepileptogenic therapy: From tuberous sclerosis to common acquired epilepsies |
| Q37419781 | Mammalian target of rapamycin (mTOR) inhibition: potential for antiseizure, antiepileptogenic, and epileptostatic therapy |
| Q37432305 | Mammalian target of rapamycin (mTOR) pathways in neurological diseases |
| Q35157985 | Mammalian target of rapamycin: hitting the bull's-eye for neurological disorders |
| Q37357038 | Measurement of autophagy flux in the nervous system in vivo |
| Q41116214 | Mechanisms of autophagy and apoptosis mediated by JAK2 signaling pathway after spinal cord injury of rats |
| Q34339959 | Mechanisms of epileptogenesis: a convergence on neural circuit dysfunction. |
| Q36390372 | Methylene blue exerts a neuroprotective effect against traumatic brain injury by promoting autophagy and inhibiting microglial activation |
| Q93139602 | Mitochondrial Division Inhibitor 1 Prevents Early-Stage Induction of Mitophagy and Accelerated Cell Death in a Rat Model of Moderate Controlled Cortical Impact Brain Injury |
| Q42550052 | Neuroprotective Effect of Simvastatin via Inducing the Autophagy on Spinal Cord Injury in the Rat Model |
| Q48847795 | Neuroprotective Effects of Resatorvid Against Traumatic Brain Injury in Rat: Involvement of Neuronal Autophagy and TLR4 Signaling Pathway |
| Q48846493 | Neuroprotective effect of ceftriaxone in a rat model of traumatic brain injury |
| Q38988452 | Neuroprotective effects of intrastriatal injection of rapamycin in a mouse model of excitotoxicity induced by quinolinic acid. |
| Q64096418 | Neuroprotective effects of rapamycin on spinal cord injury in rats by increasing autophagy and Akt signaling |
| Q27004018 | Neuroprotective strategies for traumatic brain injury: improving clinical translation |
| Q26823386 | Novel frontiers in epilepsy treatments: preventing epileptogenesis by targeting inflammation |
| Q39126886 | Novel therapeutic approaches for disease-modification of epileptogenesis for curing epilepsy. |
| Q36432388 | Oxidant stress and signal transduction in the nervous system with the PI 3-K, Akt, and mTOR cascade |
| Q27024171 | Oxidative stress induces autophagy in response to multiple noxious stimuli in retinal ganglion cells |
| Q39321120 | Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles |
| Q48181931 | Phosphorylated retinoblastoma protein (p-Rb) is involved in neuronal apoptosis after traumatic brain injury in adult rats |
| Q40947659 | Poloxamer 188 Attenuates Cerebral Hypoxia/Ischemia Injury in Parallel with Preventing Mitochondrial Membrane Permeabilization and Autophagic Activation |
| Q34999388 | Potential of immunosuppressive agents in cerebral ischaemia. |
| Q48123708 | Preconditioning with morphine protects hippocampal CA1 neurons from ischemia-reperfusion injury via activation of the mTOR pathway |
| Q34458158 | Prevention or Modification of Epileptogenesis after Brain Insults: Experimental Approaches and Translational Research |
| Q39006241 | Progress report on new antiepileptic drugs: A summary of the Thirteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIII). |
| Q38092225 | Prohibitin ligands in cell death and survival: mode of action and therapeutic potential |
| Q98892800 | Rapamycin Pretreatment Alleviates Cerebral Ischemia/Reperfusion Injury in Dose-Response Manner Through Inhibition of the Autophagy and NFκB Pathways in Rats |
| Q36917696 | Rapamycin ameliorates cadmium-induced activation of MAPK pathway and neuronal apoptosis by preventing mitochondrial ROS inactivation of PP2A. |
| Q27319659 | Rapamycin attenuates the development of posttraumatic epilepsy in a mouse model of traumatic brain injury |
| Q45041227 | Rapamycin induces of protective autophagy in vascular endothelial cells exposed to oxygen-glucose deprivation |
| Q36356365 | Rapamycin inhibits Erk1/2-mediated neuronal apoptosis caused by cadmium. |
| Q37707528 | Rapamycin inhibits lipopolysaccharide-induced neuroinflammation in vitro and in vivo |
| Q33748844 | Rapamycin is neuroprotective in a rat chronic hypertensive glaucoma model |
| Q45720343 | Rapamycin plays a neuroprotective effect after spinal cord injury via anti-inflammatory effects |
| Q48406263 | Rapamycin preconditioning attenuates transient focal cerebral ischemia/reperfusion injury in mice |
| Q54378572 | Rapamycin prevents N-methyl-D-aspartate-induced retinal damage through an ERK-dependent mechanism in rats. |
| Q35956394 | Rapamycin prevents cadmium-induced neuronal cell death via targeting both mTORC1 and mTORC2 pathways |
| Q36224840 | Rapamycin protects neurons from brain contusion‑induced inflammatory reaction via modulation of microglial activation |
| Q34974887 | Rapamycin reduces burn wound progression by enhancing autophagy in deep second-degree burn in rats |
| Q34639033 | Rapamycin reverses status epilepticus-induced memory deficits and dendritic damage |
| Q51712501 | Rapamycin suppresses microglial activation and reduces the development of neuropathic pain after spinal cord injury. |
| Q43166018 | Reevaluation of neurodegeneration in lurcher mice: constitutive ion fluxes cause cell death with, not by, autophagy |
| Q37603072 | Regulation of cell death and epileptogenesis by the mammalian target of rapamycin (mTOR): a double-edged sword? |
| Q38179991 | Remote neurodegeneration: multiple actors for one play. |
| Q50105351 | Repeated systemic treatment with rapamycin affects behavior and amygdala protein expression in rats |
| Q45852210 | Resveratrol improves neuron protection and functional recovery through enhancement of autophagy after spinal cord injury in mice |
| Q34171717 | Resveratrol inhibits inflammatory responses via the mammalian target of rapamycin signaling pathway in cultured LPS-stimulated microglial cells |
| Q34153453 | Role of Akt and mammalian target of rapamycin in functional outcome after concussive brain injury in mice |
| Q33685626 | Role of Akt-independent mTORC1 and GSK3β signaling in sublethal NMDA-induced injury and the recovery of neuronal electrophysiology and survival |
| Q26766026 | Role of Glia in Memory Deficits Following Traumatic Brain Injury: Biomarkers of Glia Dysfunction |
| Q39008983 | Role of Microglia Autophagy in Microglia Activation After Traumatic Brain Injury |
| Q38713865 | Role of hypoxia‑inducible factor‑1α in autophagic cell death in microglial cells induced by hypoxia |
| Q48092212 | Roles of autophagy and endoplasmic reticulum stress in intracerebral hemorrhage-induced secondary brain injury in rats |
| Q36224754 | Rosiglitazone exerts neuroprotective effects via the suppression of neuronal autophagy and apoptosis in the cortex following traumatic brain injury |
| Q28386911 | Sex differences in mitochondrial (dys)function: Implications for neuroprotection |
| Q27015640 | Shedding new light on neurodegenerative diseases through the mammalian target of rapamycin |
| Q35161038 | Single rapamycin administration induces prolonged downward shift in defended body weight in rats |
| Q30917098 | Structural MRI biomarkers of shared pathogenesis in autism spectrum disorder and epilepsy |
| Q40615589 | TIMP3 Attenuates the Loss of Neural Stem Cells, Mature Neurons and Neurocognitive Dysfunction in Traumatic Brain Injury |
| Q36140051 | Targeting mTOR as a novel therapeutic strategy for traumatic CNS injuries. |
| Q38024715 | The "Janus-faced role" of autophagy in neuronal sickness: focus on neurodegeneration |
| Q36228346 | The Degradation Pathway of the Mitophagy Receptor Atg32 Is Re-Routed by a Posttranslational Modification |
| Q48201452 | The Interplay Between Apolipoprotein E4 and the Autophagic-Endocytic-Lysosomal Axis. |
| Q41957358 | The Rheb-mTOR pathway is upregulated in reactive astrocytes of the injured spinal cord. |
| Q38875632 | The mTOR signalling cascade: paving new roads to cure neurological disease |
| Q48161711 | The post-therapeutic effect of rapamycin in mild traumatic brain-injured rats ensuing in the upregulation of autophagy and mitophagy. |
| Q46383880 | The role of autophagy in pro-inflammatory responses of microglia activation via mitochondrial reactive oxygen species in vitro |
| Q36304099 | The role of mTOR signaling pathway in spinal cord injury |
| Q28083902 | The role of necroptosis in neurosurgical diseases |
| Q37771378 | Therapeutic approaches to epileptogenesis--hope on the horizon |
| Q35028378 | Therapeutic role of mammalian target of rapamycin (mTOR) inhibition in preventing epileptogenesis |
| Q92514397 | Transplantation of mesenchymal stem cells overexpressing interleukin-10 induces autophagy response and promotes neuroprotection in a rat model of TBI |
| Q91893765 | Traumatic Brain Injuries: Pathophysiology and Potential Therapeutic Targets |
| Q64860576 | Traumatic Brain Injury Altered Normal Brain Signaling Pathways: Implications for Novel Therapeutics Approaches |
| Q38725858 | Tuberous sclerosis complex as a model disease for developing new therapeutics for epilepsy |
| Q28576235 | Upregulation of glutamate transporter GLT-1 by mTOR-Akt-NF-кB cascade in astrocytic oxygen-glucose deprivation |
| Q35906366 | Xuefu Zhuyu decoction, a traditional Chinese medicine, provides neuroprotection in a rat model of traumatic brain injury via an anti-inflammatory pathway |
| Q37385781 | mTOR Inhibition: From Aging to Autism and Beyond. |
| Q39429483 | mTOR as a potential treatment target for epilepsy |
| Q38112211 | mTOR inhibitors as a new therapeutic option for epilepsy. |
| Q38050335 | mTOR kinase, a key player in the regulation of glial functions: relevance for the therapy of multiple sclerosis |
| Q30111759 | Ronit Pinkas-Kramarski | notable work | P800 |
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