Distinct mechanisms for spiro-carbon formation reveal biosynthetic pathway crosstalk

scientific article published on 13 October 2013

Distinct mechanisms for spiro-carbon formation reveal biosynthetic pathway crosstalk is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/NCHEMBIO.1366
P698PubMed publication ID24121553
P5875ResearchGate publication ID257754446

P50authorKenji WatanabeQ41698682
Hisao MoriyaQ56529965
Yuta TsunematsuQ84544304
P2093author name stringKinya Hotta
Hiroshi Noguchi
Yukihiro Goda
Daigo Wakana
Noriyasu Ishikawa
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Tackling the protease problem in Saccharomyces cerevisiaeQ29620845
A biomimetic total synthesis of (-)-spirotryprostatin B and related studiesQ33915265
Fungal indole alkaloid biosynthesis: genetic and biochemical investigation of the tryptoquialanine pathway in Penicillium aethiopicumQ34163017
Optimal alignments in linear spaceQ34177047
Enzymatic processing of fumiquinazoline F: a tandem oxidative-acylation strategy for the generation of multicyclic scaffolds in fungal indole alkaloid biosynthesisQ34425191
The fumitremorgin gene cluster of Aspergillus fumigatus: identification of a gene encoding brevianamide F synthetaseQ34535018
Total synthesis and biosynthesis of the paraherquamides: an intriguing story of the biological Diels-Alder constructionQ34667626
Unraveling terminal C-domain-mediated condensation in fungal biosynthesis of imidazoindolone metabolites.Q35058923
Complexity generation in fungal peptidyl alkaloid biosynthesis: oxidation of fumiquinazoline A to the heptacyclic hemiaminal fumiquinazoline C by the flavoenzyme Af12070 from Aspergillus fumigatus.Q35355749
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Complete reconstitution of a highly reducing iterative polyketide synthaseQ40705862
Biochemical characterization of NotB as an FAD-dependent oxidase in the biosynthesis of notoamide indole alkaloidsQ40964072
A nonribosomal peptide synthetase-derived iron(III) complex from the pathogenic fungus Aspergillus fumigatusQ41518269
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Potent and specific inhibition of the breast cancer resistance protein multidrug transporter in vitro and in mouse intestine by a novel analogue of fumitremorgin C.Q44245530
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A point mutation in ftmD blocks the fumitremorgin biosynthetic pathway in Aspergillus fumigatus strain Af293.Q51015643
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P433issue12
P921main subjectAspergillus fumigatusQ134359
tryptophanQ181003
3-[[6-methoxy-3-(3-methylbut-2-enyl)-2-oxo-1H-indol-3-yl]methyl]-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dioneQ115946946
L-prolineQ20035886
nonribosomal peptide synthetase 11Q61579616
putative monooxygenase (FAD)Q61579705
nonribosomal peptide synthetase 13Q61588331
putative cytochrome P450Q61588397
O-methyltransferase ftmDQ61588445
brevianamide F prenyltransferaseQ61588489
putative cytochrome P450Q61588563
non-heme Fe(II) and alpha-ketoglutarate-dependent dioxygenaseQ61588598
fumitremorgin C monooxygenaseQ61588632
putative prenyltransferase involved in fumitremorgin B biosynthesisQ61588666
F-box domain and ankyrin repeat proteinQ61588705
3-[[6-hydroxy-2-(3-methylbut-2-enyl)-1H-indol-3-yl]methyl]-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dioneQ103817525
1,2-Dihydroxy-12-(2-methylprop-1-enyl)-10,13,19-triazapentacyclo[11.7.0.03,11.04,9.015,19]icosa-3(11),4,6,8-tetraene-14,20-dioneQ103817998
1-hydroxy-12-(2-methylprop-1-enyl)-10,13,19-triazapentacyclo[11.7.0.03,11.04,9.015,19]icosa-3(11),4,6,8-tetraene-14,20-dioneQ115946942
3-[[2,3-dihydroxy-2-(3-methylbut-2-enyl)-1H-indol-3-yl]methyl]-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dioneQ115946943
WDCWQDOJWRMQJI-UHFFFAOYSA-NQ115946944
P304page(s)818-825
P577publication date2013-10-13
P1433published inNature Chemical BiologyQ904026
P1476titleDistinct mechanisms for spiro-carbon formation reveal biosynthetic pathway crosstalk
P478volume9