| scholarly article | Q13442814 |
| P356 | DOI | 10.1126/SCIENCE.6089341 |
| P953 | full work available at URL | https://syndication.highwire.org/content/doi/10.1126/science.6089341 |
| P698 | PubMed publication ID | 6089341 |
| P2093 | author name string | P. B. Dervan | |
| M. M. Van Dyke | |||
| P2860 | cites work | The Journal of Antibiotics | Q7743552 |
| Cold Spring Harbor Symposia on Quantitative Biology | Q15758412 | ||
| DNAase footprinting a simple method for the detection of protein-DNA binding specificity | Q24615638 | ||
| 57 Sequencing end-labeled DNA with base-specific chemical cleavages | Q27860479 | ||
| Construction of a colicin E1-R factor composite plasmid in vitro: means for amplification of deoxyribonucleic acid | Q33797267 | ||
| Methidiumpropyl-EDTA-Fe(II) and DNase I footprinting report different small molecule binding site sizes on DNA | Q35685739 | ||
| The binding of echinomycin to deoxyribonucleic acid | Q42205589 | ||
| Sequence-dependent variation in the conformation of DNA | Q54403899 | ||
| Chromomycin, mithramycin, and olivomycin binding sites on heterogeneous DNA. Footprinting with methidiumpropyl-EDTA.cntdot.iron(II) | Q55062421 | ||
| Echinomycin: a bifunctional intercalating antibiotic | Q59088008 | ||
| Structure revision of the antibiotic echinomycin | Q66935158 | ||
| Cleavage of DNA with methidiumpropyl-EDTA-iron(II): reaction conditions and product analyses | Q70500973 | ||
| The molecular structure of a DNA-triostin A complex | Q70601821 | ||
| Base Specificity in the Interaction of Polynucleotides with Antibiotic Drugs | Q71157861 | ||
| Binding of actinomycin D to DNA revealed by DNase I footprinting | Q72802107 | ||
| Structure of quinomycin antibiotics. | Q78418491 | ||
| P433 | issue | 4667 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | quinoxaline | Q57263710 |
| P304 | page(s) | 1122-1127 | |
| P577 | publication date | 1984-09-01 | |
| 1984-09-14 | |||
| P1433 | published in | Science | Q192864 |
| P1476 | title | Echinomycin Binding Sites on DNA | |
| P478 | volume | 225 |
| Q36139182 | A comparison of the structure of echinomycin and triostin A complexed to a DNA fragment |
| Q34980943 | A new trinuclear complex of platinum and iron efficiently promotes cleavage of plasmid DNA. |
| Q52991597 | A novel detection technique of polyamide binding sites by photo-induced electron transfer in (Br)U substituted DNA. |
| Q31988423 | Alternative heterocycles for DNA recognition: an N-methylpyrazole/N-methylpyrrole pair specifies for A.T/T.A base pairs |
| Q38596202 | Antibiotics which can alter the rotational orientation of nucleosome core DNA. |
| Q38692127 | Antitumour drug-DNA interactions: NMR studies of echinomycin and chromomycin complexes |
| Q38301289 | Binding of quinomycin antibiotic UK-65,662 to DNA: 1H-n.m.r. studies of drug-induced changes in DNA conformation in complexes with d(ACGT)2 and d(GACGTC)2. |
| Q37479677 | Binding site size limit of the 2:1 pyrrole-imidazole polyamide-DNA motif |
| Q38211407 | Biosynthetic modularity rules in the bisintercalator family of antitumor compounds. |
| Q38342877 | Bisintercalation of ditercalinium into a d(CpGpApTpCpG)2 minihelix: a 1H- and 31P-NMR study |
| Q36724710 | Bisintercalator natural products with potential therapeutic applications: isolation, structure determination, synthetic and biological studies. |
| Q64060387 | Bortezomib and metformin opposingly regulate the expression of hypoxia-inducible factor alpha and the consequent development of chemotherapy-induced painful peripheral neuropathy |
| Q54617896 | Comparison of different footprinting methodologies for detecting binding sites for a small ligand on DNA. |
| Q36088534 | Computer assisted microdensitometric analysis of footprinting autoradiographic DATA |
| Q88613688 | Cooperative recognition of T:T mismatch by echinomycin causes structural distortions in DNA duplex |
| Q43851243 | Cyclic voltammetry of echinomycin and its interaction with double-stranded and single-stranded DNA adsorbed at the electrode |
| Q69545964 | DNA sequence preferences for the anti-cancer drug mitoxanthrone and related anthraquinones revealed by DNase I footprinting |
| Q36093941 | DNA sequence recognition by under-methylated analogues of triostin A. |
| Q40463335 | DNA structural variations produced by actinomycin and distamycin as revealed by DNAase I footprinting. |
| Q39510318 | DNA structure and perturbation by drug binding |
| Q34253203 | DNA-binding small molecules as inhibitors of transcription factors |
| Q67673101 | Differential scanning calorimetric study of the effect of intercalators and other kinds of DNA-binding drugs on the stepwise melting of plasmid DNA |
| Q42823979 | Dissociation of the AT-specific bifunctional intercalator [N-MeCys3,N-MeCys7]TANDEM from TpA sites in DNA |
| Q46966611 | Dual effect of echinomycin on hypoxia-inducible factor-1 activity under normoxic and hypoxic conditions |
| Q40418380 | Echinomycin and distamycin induce rotation of nucleosome core DNA. |
| Q35800183 | Echinomycin binding to alternating AT |
| Q40515848 | Echinomycin binding to the sequence CG(AT)nCG alters the structure of the central AT region |
| Q41540359 | Echinomycin, a bis-intercalating agent, induces C→T mutations via cytosine deamination |
| Q39839425 | Echinomycin: the first bifunctional intercalating agent in clinical trials |
| Q37369127 | Energetics of echinomycin binding to DNA. |
| Q52926478 | Enhancement in intramolecular interactions and in vitro biological activity of a tripodal tetradentate system upon complexation. |
| Q47994680 | Experimental measurement of binding energy, selectivity, and allostery using fluctuation theorems |
| Q40564686 | Footprinting at low temperatures: evidence that ethidium and other simple intercalators can discriminate between different nucleotide sequences |
| Q38298047 | Footprinting methods for analysis of pyrrole-imidazole polyamide/DNA complexes |
| Q42794637 | Footprinting studies on the effect of echinomycin on the structure of a bent DNA fragment |
| Q57696989 | HIF-1 inhibitors as anti-cancer therapy |
| Q72391038 | High resolution mid-prophase human chromosomes induced by echinomycin and ethidium bromide |
| Q43723831 | High-resolution footprinting studies of drug-DNA complexes using chemical and enzymatic probes |
| Q34595139 | Hoogsteen base pairs proximal and distal to echinomycin binding sites on DNA |
| Q36341443 | Hypoxia inducible factor 1α expression and effects of its inhibitors in canine lymphoma |
| Q61660008 | Hypoxia inducible factor down-regulation, cancer and cancer stem cells (CSCs): ongoing success stories |
| Q38097867 | Hypoxia inducible factor pathway inhibitors as anticancer therapeutics. |
| Q81589359 | Hypoxia-inducible factor 1 inhibitors |
| Q40658370 | Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells |
| Q33266897 | Improved nuclear localization of DNA-binding polyamides |
| Q35800171 | Interaction of echinomycin with An.Tn. and (AT)nregions flanking its CG binding site |
| Q27728559 | Interactions of quinoxaline antibiotic and DNA: the molecular structure of a triostin A-d(GCGTACGC) complex |
| Q40567852 | Kinetic evidence that echinomycin migrates between potential DNA binding sites |
| Q42274046 | Localized chemical reactivity in DNA associated with the sequence-specific bisintercalation of echinomycin |
| Q40762697 | Mechanism of DNA-drug interactions |
| Q40560729 | Methidiumpropyl-EDTA-iron(II) cleavage of ribosomal DNA chromatin from Dictyostelium discoideum |
| Q41857906 | Modulating hypoxia-inducible transcription by disrupting the HIF-1-DNA interface |
| Q37397055 | Molecular mechanical studies of d(CGTACG)2: complex of triostin A with the middle A - T base pairs in either Hoogsteen or Watson-Crick pairing |
| Q35012800 | Molecular recognition of B-DNA by Hoechst 33258. |
| Q38829453 | Mononuclear iron(iii) complexes of tridentate ligands with efficient nuclease activity and studies of their cytotoxicity |
| Q90719841 | Multiple weak intercalation as a strategy for the inhibition of polymerases |
| Q36286099 | Negative regulation of human growth hormone gene expression by insulin is dependent on hypoxia-inducible factor binding in primary non-tumor pituitary cells |
| Q52644664 | Non-covalent duplex to duplex crosslinking of DNA in solution revealed by single molecule force spectroscopy. |
| Q46570065 | On the pairing rules for recognition in the minor groove of DNA by pyrrole-imidazole polyamides |
| Q33491521 | Phase II trial of echinomycin in patients with advanced or recurrent colorectal cancer |
| Q33284910 | Probing ligand binding to duplex DNA using KMnO4 reactions and electrospray ionization tandem mass spectrometry |
| Q38330966 | Proton NMR studies of [N-MeCys3,N-MeCys7]TANDEM binding to DNA oligonucleotides: sequence-specific binding at the TpA site |
| Q38328640 | Proton NMR study of the [d(ACGTATACGT)]2-2echinomycin complex: conformational changes between echinomycin binding sites |
| Q38337352 | Proton exchange kinetics in [d(ACGTATACGT)]2-echinomycin and [d(ACGTTAACGT)]2-echinomycin complexes |
| Q34732038 | Quantitative microarray profiling of DNA-binding molecules |
| Q27936377 | Reprogramming of tRNA modifications controls the oxidative stress response by codon-biased translation of proteins |
| Q43836776 | Retinoids and control of epithelial differentiation and keratin biosynthesis in hamster trachea |
| Q35754397 | Screening of threading bis-intercalators binding to duplex DNA by electrospray ionization tandem mass spectrometry |
| Q38322351 | Sequence-specific binding of [N-MeCys3,N-MeCys7]TANDEM to TpA |
| Q40544774 | Sequence-specific binding of luzopeptin to DNA. |
| Q41464146 | Single molecule high-throughput footprinting of small and large DNA ligands |
| Q43184421 | Single-molecule kinetics and footprinting of DNA bis-intercalation: the paradigmatic case of Thiocoraline. |
| Q38335588 | Solution structure of the luzopeptin-DNA complex |
| Q51554951 | Solution-phase synthesis and biological evaluation of triostin A and its analogues. |
| Q59092559 | Structure of DNase I at 2.0 Å resolution suggests a mechanism for binding to and cutting DNA |
| Q40972459 | Synthesis and Biological Evaluation of Kibdelone C and Its Simplified Derivatives |
| Q38339320 | Synthesis of key sandramycin analogs: systematic examination of the intercalation chromophore |
| Q58994430 | Synthesis, Crystal Structure, Antioxidant, Antimicrobial, and Mutagenic Activities and DNA Interaction Studies of Ni(II) Schiff Base 4-Methoxy-3-benzyloxybenzaldehyde Thiosemicarbazide Complexes |
| Q35759208 | Targeting Hypoxia-Inducible Factor 1α in a New Orthotopic Model of Glioblastoma Recapitulating the Hypoxic Tumor Microenvironment |
| Q40535130 | The 2-amino group of guanine is absolutely required for specific binding of the anti-cancer antibiotic echinomycin to DNA |
| Q71656145 | The purine 2-amino group as a critical recognition element for binding of small molecules to DNA |
| Q38352902 | Theoretical analysis of the footprinting experiment |
| Q33851888 | Unstable Hoogsteen base pairs adjacent to echinomycin binding sites within a DNA duplex |
| Q71006852 | Visualising the dissociation of sequence selective ligands from individual binding sites on DNA |
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