Levetiracetam is neuroprotective in murine models of closed head injury and subarachnoid hemorrhage

scientific article published in January 2006

Levetiracetam is neuroprotective in murine models of closed head injury and subarachnoid hemorrhage is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1031949315
P356DOI10.1385/NCC:5:1:71
P698PubMed publication ID16960300

P2093author name stringJunling Gao
Daniel T Laskowitz
David S Warner
Huaxin Sheng
John R Lynch
David L McDonagh
Haichen Wang
Timothy F Lassiter
P2860cites workEffects of levetiracetam on the production of nitric oxide--an in vivo studyQ45292920
Potential effects of common drugs on stroke recoveryQ48482996
A novel therapeutic derived from apolipoprotein E reduces brain inflammation and improves outcome after closed head injuryQ49071765
EPILEPSY AFTER RUPTURED INTRACRANIAL ANEURYSM.Q50285041
Mechanisms of endothelium-dependent vascular smooth muscle relaxation elicited by bradykinin and VIP.Q50900490
Epileptic seizures after subarachnoid hemorrhage.Q51053340
A novel peptide vasoconstrictor, endothelin, is produced by vascular endothelium and modulates smooth muscle Ca2+ channelsQ69851259
Phenytoin-induced thrombocytopeniaQ73217810
Effective improvement of the cerebral vasospasm after subarachnoid hemorrhage with low-dose nitroglycerinQ73344084
Reversal and prevention of cerebral vasospasm by intracarotid infusions of nitric oxide donors in a primate model of subarachnoid hemorrhageQ73826660
Anticonvulsant prophylaxis and timing of seizures after aneurysmal subarachnoid hemorrhageQ74047731
Mouse model of subarachnoid hemorrhage associated cerebral vasospasm: methodological analysisQ74460331
Apolipoprotein E affects the central nervous system response to injury and the development of cerebral edemaQ77466577
A novel apoE-derived therapeutic reduces vasospasm and improves outcome in a murine model of subarachnoid hemorrhageQ82648185
The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetamQ24561949
Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A)Q24655420
The anti-epileptic drug levetiracetam reverses the inhibition by negative allosteric modulators of neuronal GABA- and glycine-gated currentsQ30498688
Effect of levetiracetam on the pharmacokinetics of adjunctive antiepileptic drugs: a pooled analysis of data from randomized clinical trialsQ30986943
Guidelines for nonemergency use of parenteral phenytoin products: proceedings of an expert panel consensus process. Panel on Nonemergency Use of Parenteral Phenytoin ProductsQ33794387
Fluoro-Jade B: a high affinity fluorescent marker for the localization of neuronal degenerationQ33915341
Levetiracetam. A review of its adjunctive use in the management of partial onset seizuresQ34086045
A randomized, double-blind study of phenytoin for the prevention of post-traumatic seizuresQ34155061
Practice parameter: antiepileptic drug prophylaxis in severe traumatic brain injury: report of the Quality Standards Subcommittee of the American Academy of NeurologyQ34170263
Phenytoin exposure is associated with functional and cognitive disability after subarachnoid hemorrhageQ34386555
Clinically important drug interactions in epilepsy: interactions between antiepileptic drugs and other drugsQ35183961
Levetiracetam safety profiles and tolerability in epilepsy patients.Q35873716
Dilantin hypersensitivity reaction.Q40670245
Intravenous administration of fosphenytoin: options for the management of seizuresQ40997741
Phenytoin-induced hepatitis, rhabdomyolysis, and renal dysfunctionQ42198583
Evidence for a unique profile of levetiracetam in rodent models of seizures and epilepsyQ42539954
Reversal of cerebral vasospasm using an intrathecally administered nitric oxide donorQ42540664
Neuroprotective properties of the novel antiepileptic drug levetiracetam in the rat middle cerebral artery occlusion model of focal cerebral ischemiaQ43683385
Simvastatin increases endothelial nitric oxide synthase and ameliorates cerebral vasospasm resulting from subarachnoid hemorrhageQ44240509
Expression of brain-derived neurotrophic factor (BDNF) and inducible nitric oxide synthase (iNOS) in rat astrocyte cultures treated with Levetiracetam.Q44451294
Psychiatric adverse events during levetiracetam therapyQ44578346
A new model of diffuse brain injury in rats. Part I: Pathophysiology and biomechanicsQ45091283
A new model of diffuse brain injury in rats. Part II: Morphological characterizationQ45091286
P433issue1
P921main subject(S)-etiracetamQ417227
murine modelQ122890741
P304page(s)71-78
P577publication date2006-01-01
P1433published inNeurocritical CareQ15745303
P1476titleLevetiracetam is neuroprotective in murine models of closed head injury and subarachnoid hemorrhage
P478volume5

Reverse relations

cites work (P2860)
Q39123432Abbreviated levetiracetam treatment effects on behavioural and histological outcomes after experimental TBI.
Q64120494An experimental study on the early diagnosis of traumatic brain injury in rabbits based on a noncontact and portable system
Q28315817CB1 and CB2 Cannabinoid Receptor Antagonists Prevent Minocycline-Induced Neuroprotection Following Traumatic Brain Injury in Mice
Q37865100Comparison of short-duration levetiracetam with extended-course phenytoin for seizure prophylaxis after subarachnoid hemorrhage.
Q84965433Dose-dependent ultrastructural and morphometric alterations after erythropoietin treatment in rat femoral artery vasospasm model
Q36640693Effects of Different Doses of Levetiracetam on Aquaporin 4 Expression in Rats with Brain Edema Following Fluid Percussion Injury
Q33634989Female gonadal hormone effects on microglial activation and functional outcomes in a mouse model of moderate traumatic brain injury
Q28537667Insights from zebrafish and mouse models on the activity and safety of ar-turmerone as a potential drug candidate for the treatment of epilepsy
Q48239099Lacosamide improves outcome in a murine model of traumatic brain injury
Q41910193Levetiracetam in Neonatal Seizures as First-line Treatment: A Prospective Study.
Q33761706Levetiracetam inhibits both ryanodine and IP3 receptor activated calcium induced calcium release in hippocampal neurons in culture.
Q37688063Levetiracetam: a comprehensive review
Q31110554Levetiracetam: the profile of a novel anticonvulsant drug-part I: preclinical data.
Q38244403Long-term comparison of GOS-E scores in patients treated with phenytoin or levetiracetam for posttraumatic seizure prophylaxis after traumatic brain injury
Q37209019Management of post-subarachnoid hemorrhage vasospasm
Q64055514Neurobehavioral Deficits After Subarachnoid Hemorrhage in Mice: Sensitivity Analysis and Development of a New Composite Score
Q26830325Neurobehavioral effects of levetiracetam in patients with traumatic brain injury
Q33496591Neurological and neurobehavioral assessment of experimental subarachnoid hemorrhage
Q48896314Neuroprotection and anti-seizure effects of levetiracetam in a rat model of penetrating ballistic-like brain injury
Q38684428Neuroprotection as a Potential Therapeutic Perspective in Neurodegenerative Diseases: Focus on Antiepileptic Drugs
Q36034824Neuroprotection in subarachnoid hemorrhage
Q50736416Neuroprotective, neuroplastic, and neurobehavioral effects of daily treatment with levetiracetam in experimental traumatic brain injury.
Q48067659Opposing effects of traumatic brain injury on excitatory synaptic function in the lateral amygdala in the absence and presence of preinjury stress
Q83862861Optimal antiepileptic drug use for patients with subarachnoid hemorrhage
Q36060634Pharmacologic Neuroprotection for Functional Outcomes After Traumatic Brain Injury: A Systematic Review of the Clinical Literature
Q27004055Post-traumatic epilepsy: current and emerging treatment options
Q89164767Prophylactic Seizure Medication and Health-Related Quality of Life After Intracerebral Hemorrhage
Q37276387Prospects of levetiracetam as a neuroprotective drug against status epilepticus, traumatic brain injury, and stroke
Q38166331Seizure prophylaxis in neurocritical care: a review of evidence-based support.
Q38047704Seizures after aneurysmal subarachnoid hemorrhage: a systematic review of outcomes
Q37374151Statins in traumatic brain injury
Q37985377Status epilepticus: a review, with emphasis on refractory cases.
Q47417746The Antiepileptic Drug Levetiracetam Protects Against Quinolinic Acid-Induced Toxicity in the Rat Striatum
Q28535091The antiepileptic drug levetiracetam suppresses non-convulsive seizure activity and reduces ischemic brain damage in rats subjected to permanent middle cerebral artery occlusion
Q37287407Towards clinical management of traumatic brain injury: a review of models and mechanisms from a biomechanical perspective
Q84975640Traumatic Brain Injury Exacerbates Neurodegenerative Pathology: Improvement with an Apolipoprotein E-Based Therapeutic

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