Single-channel activity of the Ca2+-dependent K+ channel is modulated by FK506 and rapamycin

scientific article published in March 1998

Single-channel activity of the Ca2+-dependent K+ channel is modulated by FK506 and rapamycin is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0006-8993(97)01435-2
P698PubMed publication ID9555045

P2093author name stringMaeda K
Yasuda M
Hashimoto T
Kawamata T
Nakai M
Tanaka C
Taniguchi T
Terashima A
P2860cites workCalcineurin associated with the inositol 1,4,5-trisphosphate receptor-FKBP12 complex modulates Ca2+ fluxQ28270468
Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexesQ28277749
Immunosuppressants implicate protein phosphatase regulation of K+ channels in guard cellsQ36160975
Role of tyrosine phosphorylation in potassium channel activation. Functional association with prolactin receptor and JAK2 tyrosine kinase.Q36685326
Immunophilins and nervous systemQ40429841
Cellular functions of immunophilinsQ41075701
Stabilization of calcium release channel (ryanodine receptor) function by FK506-binding proteinQ41467443
FKBP12-FK506 Complex Inhibits Phosphatase Activity of Two Mammalian Isoforms of Calcineurin Irrespective of Their Substrates or Activation Mechanisms11Q41572031
Temperature dependence of drug blockade of a calcium-dependent potassium channel in cultured hippocampal neuronsQ42580984
Regulation of NMDA channel function by endogenous Ca(2+)-dependent phosphataseQ46364713
Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin AQ46979889
Rat hippocampal neurons in dispersed cell cultureQ48292684
Protein Kinase Activity Closely Associated with a Reconstituted Calcium-Activated Potassium ChannelQ48675187
Somatostatin stimulates Ca2+-activated K+ channels through protein dephosphorylationQ48707748
On the mechanism of modulation of transient outward current in cultured rat hippocampal neurons by di- and trivalent cations.Q51615839
Single channel activity of the ryanodine receptor calcium release channel is modulated by FK-506.Q54022385
Voltage-gated potassium currents in stratum oriens-alveus inhibitory neurones of the rat CA1 hippocampus.Q54158798
Regulation of NMDA receptors by tyrosine kinases and phosphatasesQ57083922
Potassium channel stimulation by natriuretic peptides through cGMP-dependent dephosphorylationQ59063032
Potassium conductances underlying repolarization and after-hyperpolarization in rat CA1 hippocampal interneuronesQ70939179
P433issue1-2
P407language of work or nameEnglishQ1860
P304page(s)255-258
P577publication date1998-03-01
P1433published inBrain ResearchQ4955782
P1476titleSingle-channel activity of the Ca2+-dependent K+ channel is modulated by FK506 and rapamycin
P478volume786

Reverse relations

cites work (P2860)
Q48093388A resurging boom in new drugs for epilepsy and brain disorders.
Q51801462Calcineurin-independent inhibition of KV1.3 by FK-506 (tacrolimus): a novel pharmacological property.
Q39475200Comparative pharmacodynamic analysis of Q-T interval prolongation induced by the macrolides clarithromycin, roxithromycin, and azithromycin in rats
Q43872400Cyclosporin A, FK506 and rapamycin produce multiple, temporally distinct, effects on memory following single-trial, passive avoidance training in the chick.
Q34973847Disrupting function of FK506-binding protein 1b/12.6 induces the Ca²+-dysregulation aging phenotype in hippocampal neurons
Q39820135Effects of rapamycin on gene expression, morphology, and electrophysiological properties of rat hippocampal neurons
Q33807200Effects of serine/threonine protein phosphatases on ion channels in excitable membranes
Q42521693Electrophysiological actions of cyclosporin A and tacrolimus on rat hippocampal CA1 pyramidal neurons
Q27024547Finding a better drug for epilepsy: the mTOR pathway as an antiepileptogenic target
Q38582924How does the ketogenic diet work? Four potential mechanisms
Q38010957Insights into CNS ageing from animal models of senescence.
Q40743752Insulin release and suppression by tacrolimus, rapamycin and cyclosporin A are through regulation of the ATP-sensitive potassium channel
Q43253697Neuroprotective action of FK-506 (tacrolimus) after seizures induced with pilocarpine: quantitative and topographic elemental analysis of brain tissue
Q38214869Pathogenetic mechanisms of focal cortical dysplasia
Q39006241Progress report on new antiepileptic drugs: A summary of the Thirteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIII).
Q73964528Rapamycin and FK506 induce long-term potentiation by pairing stimulation via an intracellular Ca(2+) signaling mechanism in rat hippocampal CA1 neurons
Q86910950Rapamycin has a beneficial effect on controlling epilepsy in children with tuberous sclerosis complex: results of 7 children from a cohort of 86
Q44437992Rapamycin: signaling in vascular smooth muscle
Q41484523Targeting Kv1.3 channels to reduce white matter pathology after traumatic brain injury
Q38204833Understanding the hysteresis loop conundrum in pharmacokinetic/pharmacodynamic relationships
Q38112211mTOR inhibitors as a new therapeutic option for epilepsy.

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