Single- and multiple-dose kinetics of d-fenfluramine in rats given anorectic and toxic doses

scientific article published in February 1992

Single- and multiple-dose kinetics of d-fenfluramine in rats given anorectic and toxic doses is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3109/00498259209046620
P698PubMed publication ID1632111

P2093author name stringCaccia S
Garattini S
Fracasso C
Anelli M
Ferrarese A
P2860cites workPharmacological treatments that affect CNS activity: serotoninQ39661358
Drug treatment and obesityQ40253392
Fenfluramine and brain serotoninQ40692563
Effects of high-dose fenfluramine treatment on monoamine uptake sites in rat brain: assessment using quantitative autoradiographyQ41197985
Species differences in the rate of disappearance of fenfluramine and its effects on brain serotonin neuronsQ44280223
Reversible, short-lasting, and dose-dependent effect of (+)-fenfluramine on neocortical serotonergic axonsQ48722357
Immunohistochemical study of short- and long-term effects of DL-fenfluramine on the serotonergic innervation of the rat hippocampal formationQ48794164
Effects of intracerebroventricular administration of d-fenfluramine and d-norfenfluramine, as a single injection or 2-hr infusion, on serotonin in brain: relationship to concentrations of drugs in brainQ48799923
Anatomic evidence for a neurotoxic effect of (+/-)-fenfluramine upon serotonergic projections in the rat.Q49057618
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)217-226
P577publication date1992-02-01
P1433published inXenobioticaQ1360678
P1476titleSingle- and multiple-dose kinetics of d-fenfluramine in rats given anorectic and toxic doses
P478volume22

Reverse relations

cites work (P2860)
Q70674116Anorectic effect and brain concentrations of D-fenfluramine in the marmoset: relationship to the in vivo and in vitro effects on serotonergic mechanisms
Q34663159Appetite suppression by commonly used drugs depends on 5-HT receptors but not on 5-HT availability
Q71901657Effect of d-fenfluramine on the indole contents of the rat brain after treatment with different inducers of cytochrome P450 isoenzymes
Q48860049Effects of repeated oral doses of dexnorfenfluramine on 5-HT levels and 5-HT uptake sites in rat brain
Q43557254Elevations in plasmatic titers of corticosterone and aldosterone, in the absence of changes in ACTH, testosterone, or glial fibrillary acidic protein, 72 h following D,L-fenfluramine or D-fenfluramine administration to rats
Q34461106Indan analogs of fenfluramine and norfenfluramine have reduced neurotoxic potential
Q52262139Measurement of dexfenfluramine metabolism in rat liver microsomes by gas chromatography–mass spectrometry
Q48650603Neuropharmacological effects of low and high doses of repeated oral dexfenfluramine in rats: a comparison with fluoxetine
Q28138124Serotonin transporters, serotonin release, and the mechanism of fenfluramine neurotoxicity
Q48319549The role of d-norfenfluramine in the indole-depleting effect of d-fenfluramine in the rat