Curcumin ameliorates insulin signalling pathway in brain of Alzheimer's disease transgenic mice

scientific article published on 27 July 2016

Curcumin ameliorates insulin signalling pathway in brain of Alzheimer's disease transgenic mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1177/0394632016659494
P932PMC publication ID5806850
P698PubMed publication ID27466310

P2093author name stringJing Shi
Hui Fan
Ying Ren
Hui-Li Feng
Hui-Zi Dang
Jin-Duo Yang
Peng-Wen Wang
Xiao-Pei Chen
Jin-Zhou Tian
Ying-Xue Rao
P2860cites workPathogenesis of synaptic degeneration in Alzheimer's disease and Lewy body diseaseQ26853610
Curcumin as a therapeutic agent in dementia: a mini systematic review of human studiesQ27012755
Brain insulin resistance and deficiency as therapeutic targets in Alzheimer's diseaseQ28259585
Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer's diseaseQ34489699
Curcumin and curcumin-like molecules: from spice to drugsQ34650539
Insulin receptor substrate 2 expression and involvement in neuronal insulin resistance in diabetic neuropathyQ35095336
Immunohistochemical assessment of intrinsic and extrinsic markers of hypoxia in reproductive tissue: differential expression of HIF1α and HIF2α in rat oviduct and endometrium.Q35106512
Curcumin Attenuates Amyloid-β Aggregate Toxicity and Modulates Amyloid-β Aggregation PathwayQ35830463
Insulin resistance in the nervous systemQ36084516
Ganoderma lucidum ethanol extract inhibits the inflammatory response by suppressing the NF-κB and toll-like receptor pathways in lipopolysaccharide-stimulated BV2 microglial cellsQ36603958
Curcumin and neurodegenerative diseases: a perspectiveQ38016212
Neuroprotective properties of curcumin in Alzheimer's disease--merits and limitations.Q38127805
GSK3 in Alzheimer's disease: mind the isoformsQ38164295
Insulin dysfunction and Tau pathology.Q38191590
Deregulation of brain insulin signaling in Alzheimer's diseaseQ38197947
Animal models of dementia and cognitive dysfunctionQ38234442
Examining the potential clinical value of curcumin in the prevention and diagnosis of Alzheimer's disease.Q38664541
Age-dependent accumulation of soluble amyloid beta (Abeta) oligomers reverses the neuroprotective effect of soluble amyloid precursor protein-alpha (sAPP(alpha)) by modulating phosphatidylinositol 3-kinase (PI3K)/Akt-GSK-3beta pathway in Alzheimer mQ42737591
Pioglitazone ameliorates intracerebral insulin resistance and tau-protein hyperphosphorylation in rats with type 2 diabetesQ43503238
Mechanisms and effects of curcumin on spatial learning and memory improvement in APPswe/PS1dE9 miceQ43590947
Rosiglitazone attenuates learning and memory deficits in Tg2576 Alzheimer miceQ46974377
Downregulation of PI3K/Akt/mTOR signaling pathway in curcumin-induced autophagy in APP/PS1 double transgenic miceQ48650093
Effects of curcumin on synapses in APPswe/PS1dE9 miceQ48849905
P433issue4
P921main subjectAlzheimer's diseaseQ11081
curcuminQ312266
P304page(s)734-741
P577publication date2016-07-27
P1433published inInternational Journal of Immunopathology and PharmacologyQ15752195
P1476titleCurcumin ameliorates insulin signalling pathway in brain of Alzheimer's disease transgenic mice
P478volume29

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cites work (P2860)
Q94464611A network pharmacology-based study on Alzheimer disease prevention and treatment of Qiong Yu Gao
Q47647286Chronic diseases, inflammation, and spices: how are they linked?
Q42675935Curcumin inhibits endoplasmic reticulum stress induced by cerebral ischemia-reperfusion injury in rats
Q58776704Curcumin-loaded PLGA-PEG nanoparticles conjugated with B6 peptide for potential use in Alzheimer's disease
Q90396206Dietary habits, lifestyle factors and neurodegenerative diseases
Q52574481Implications of PI3K/AKT/PTEN Signaling on Superoxide Dismutases Expression and in the Pathogenesis of Alzheimer's Disease.
Q90012974Mikania Micrantha Improved Memory Perform on Dementia Model
Q47657359Protective Effects of Indian Spice Curcumin Against Amyloid-β in Alzheimer's Disease
Q64076343Serum and cerebrospinal fluid tau protein level as biomarkers for evaluating acute spinal cord injury severity and motor function outcome
Q47862033Supplementation with Curcuma longa reverses neurotoxic and behavioral damage in models of Alzheimer's disease: A systematic review.
Q39319459The Mechanisms of Action of Curcumin in Alzheimer's Disease

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