scholarly article | Q13442814 |
review article | Q7318358 |
P356 | DOI | 10.1016/S0376-8716(98)00068-4 |
P698 | PubMed publication ID | 9716932 |
P50 | author | Susan Amara | Q18386608 |
P2093 | author name string | M S Sonders | |
P2860 | cites work | Expression cloning of a cocaine- and antidepressant-sensitive human noradrenaline transporter | Q24296225 |
Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter | Q24310836 | ||
Protein kinase C activation regulates human serotonin transporters in HEK-293 cells via altered cell surface expression | Q24311349 | ||
An excitatory amino-acid transporter with properties of a ligand-gated chloride channel | Q24323343 | ||
Expression cloning of a reserpine-sensitive vesicular monoamine transporter | Q24563187 | ||
Identification and characterization of the vesicular GABA transporter | Q28253052 | ||
Functional identification and molecular cloning of a human brain vesicle monoamine transporter | Q28256704 | ||
Mechanisms of amphetamine action revealed in mice lacking the dopamine transporter | Q28263277 | ||
Anterior pituitary hypoplasia and dwarfism in mice lacking the dopamine transporter | Q28504671 | ||
VMAT2 knockout mice: heterozygotes display reduced amphetamine-conditioned reward, enhanced amphetamine locomotion, and enhanced MPTP toxicity | Q28512294 | ||
Cloning and expression of a rat brain GABA transporter | Q28566313 | ||
Cloning and functional characterization of a cocaine-sensitive dopamine transporter | Q28577393 | ||
A cDNA that suppresses MPP+ toxicity encodes a vesicular amine transporter | Q28581165 | ||
Cocaine receptors on dopamine transporters are related to self-administration of cocaine | Q29619876 | ||
Gene transfer of a reserpine-sensitive mechanism of resistance to N-methyl-4-phenylpyridinium | Q33191656 | ||
Cloning of the cocaine-sensitive bovine dopamine transporter | Q33269223 | ||
Membrane transport mechanisms probed by capacitance measurements with megahertz voltage clamp | Q33766008 | ||
Single-channel currents produced by the serotonin transporter and analysis of a mutation affecting ion permeation | Q34041264 | ||
Neurotransmitter transporters: three distinct gene families. | Q34335328 | ||
Amphetamine and other weak bases act to promote reverse transport of dopamine in ventral midbrain neurons. | Q34359201 | ||
Dopamine transporter ligand binding domains. Structural and functional properties revealed by limited proteolysis | Q34388694 | ||
Neurobiology of addiction | Q34390258 | ||
Multiple ionic conductances of the human dopamine transporter: the actions of dopamine and psychostimulants. | Q34413154 | ||
Charged residues in transmembrane domains II and XI of a vesicular monoamine transporter form a charge pair that promotes high affinity substrate recognition | Q34416815 | ||
The role of vesicular transport proteins in synaptic transmission and neural degeneration | Q34418613 | ||
2-Carbomethoxy-3-aryl-8-oxabicyclo[3.2.1]octanes: potent non-nitrogen inhibitors of monoamine transporters | Q34437247 | ||
Cloning and expression of a cocaine-sensitive rat dopamine transporter | Q34983785 | ||
The transport of neurotransmitters into synaptic vesicles | Q35268988 | ||
Molecular cloning of a putative vesicular transporter for acetylcholine | Q35865884 | ||
Chimeric dopamine-norepinephrine transporters delineate structural domains influencing selectivity for catecholamines and 1-methyl-4-phenylpyridinium | Q35993022 | ||
Cloning and expression of the vesamicol binding protein from the marine ray Torpedo. Homology with the putative vesicular acetylcholine transporter UNC-17 from Caenorhabditis elegans | Q36745944 | ||
Dopamine transporter site-directed mutations differentially alter substrate transport and cocaine binding | Q37164373 | ||
Cloning and expression of a functional serotonin transporter from rat brain | Q38332277 | ||
Cloning of a serotonin transporter affected by antidepressants | Q38332817 | ||
Cloning and expression of a cocaine-sensitive dopamine transporter complementary DNA. | Q38332823 | ||
Knockout of the vesicular monoamine transporter 2 gene results in neonatal death and supersensitivity to cocaine and amphetamine. | Q39758343 | ||
The role of dopamine in drug abuse viewed from the perspective of its role in motivation | Q40480641 | ||
A molecular glimpse of vesicular monoamine transporters. | Q40622940 | ||
Permeation properties of neurotransmitter transporters. | Q40624625 | ||
Neurotransmitter transporters | Q40628099 | ||
Neurotransmitter transporters: recent progress | Q40708857 | ||
From synapse to vesicle: the reuptake and storage of biogenic amine neurotransmitters | Q40713073 | ||
A review of the effects of dopaminergic agents on humans, animals, and drug-seeking behavior, and its implications for medication development. Focus on GBR 12909. | Q40945424 | ||
The rat serotonin transporter: identification of cysteine residues important for substrate transport | Q41066643 | ||
Channels in transporters. | Q41103322 | ||
N-linked oligosaccharides are required for cell surface expression of the norepinephrine transporter but do not influence substrate or inhibitor recognition. | Q41180661 | ||
Antipeptide antibodies confirm the topology of the human norepinephrine transporter | Q41349358 | ||
Dopamine transporter mutants selectively enhance MPP+ transport | Q41530541 | ||
Vesicular transport regulates monoamine storage and release but is not essential for amphetamine action. | Q46083768 | ||
Chimeric vesicular monoamine transporters identify structural domains that influence substrate affinity and sensitivity to tetrabenazine | Q46100910 | ||
Ion binding and permeation at the GABA transporter GAT1. | Q46231076 | ||
H+ permeation and pH regulation at a mammalian serotonin transporter. | Q46493814 | ||
Individual residues contribute to multiple differences in ligand recognition between vesicular monoamine transporters 1 and 2. | Q46516697 | ||
Steady states, charge movements, and rates for a cloned GABA transporter expressed in Xenopus oocytes. | Q46655666 | ||
Conducting states of a mammalian serotonin transporter. | Q46682322 | ||
Multiple residues contribute independently to differences in ligand recognition between vesicular monoamine transporters 1 and 2. | Q46833644 | ||
Amphetamine and other psychostimulants reduce pH gradients in midbrain dopaminergic neurons and chromaffin granules: a mechanism of action. | Q48843310 | ||
Analysis of the transmembrane topology and membrane assembly of the GAT-1 gamma-aminobutyric acid transporter | Q48956982 | ||
Drosophila serotonin transporters have voltage-dependent uptake coupled to a serotonin-gated ion channel | Q48957994 | ||
Dopamine transporter cysteine mutants: second extracellular loop cysteines are required for transporter expression. | Q51609169 | ||
Structure-activity relationship studies of N-sulfonyl analogs of cocaine: role of ionic interaction in cocaine binding. | Q51624952 | ||
GABA transport and calcium dynamics in horizontal cells from the skate retina | Q70939145 | ||
Glutamate increases cytosolic calcium in GH 3 pituitary cells acting via a high‐affinity glutamate transporter | Q71846211 | ||
External cysteine residues in the serotonin transporter | Q73139649 | ||
P433 | issue | 1-2 | |
P921 | main subject | neurotransmitter | Q162657 |
P304 | page(s) | 87-96 | |
P577 | publication date | 1998-06-01 | |
P1433 | published in | Drug and Alcohol Dependence | Q5308875 |
P1476 | title | Neurotransmitter transporters as molecular targets for addictive drugs | |
P478 | volume | 51 |
Q36172632 | 18F-FECNT: Validation as PET dopamine transporter ligand in parkinsonism |
Q30511824 | 4-(4-(dimethylamino)phenyl)-1-methylpyridinium (APP+) is a fluorescent substrate for the human serotonin transporter. |
Q36319757 | 5-HT(1B) autoreceptor regulation of serotonin transporter activity in synaptosomes |
Q27653127 | A competitive inhibitor traps LeuT in an open-to-out conformation |
Q48042894 | A partially-open inward-facing intermediate conformation of LeuT is associated with Na+ release and substrate transport. |
Q36369107 | Adolescents with prenatal cocaine exposure show subtle alterations in striatal surface morphology and frontal cortical volumes |
Q47565964 | Allosteric modulation of human dopamine transporter activity under conditions promoting its dimerization. |
Q38873771 | Alpha-synuclein modulates dopamine neurotransmission. |
Q27324017 | Altered neurocircuitry in the dopamine transporter knockout mouse brain |
Q27312593 | Altered reward circuitry in the norepinephrine transporter knockout mouse |
Q37048354 | Amphetamine activates an amine-gated chloride channel to generate behavioral effects in Caenorhabditis elegans |
Q36464578 | Amphetamine modulation of long‐term potentiation in the prefrontal cortex: dose dependency, monoaminergic contributions, and paradoxical rescue in hyperdopaminergic mutant |
Q32063805 | Amphetamine selectively blocks inhibitory glutamate transmission in dopamine neurons |
Q24291930 | Amphetamine, 3,4-methylenedioxymethamphetamine, lysergic acid diethylamide, and metabolites of the catecholamine neurotransmitters are agonists of a rat trace amine receptor |
Q40929859 | An intronic polymorphic domain often associated with susceptibility to affective disorders has allele dependent differential enhancer activity in embryonic stem cells |
Q37268774 | Appetite suppressants, cardiac valve disease and combination pharmacotherapy |
Q44699716 | Association between polymorphism of the dopamine transporter gene and early smoking onset: an interaction risk on nicotine dependence |
Q24649777 | Augmented behavioral response and enhanced synaptosomal calcium transport induced by repeated cocaine administration are decreased by calcium channel blockers |
Q28274119 | Balance between dopamine and serotonin release modulates behavioral effects of amphetamine-type drugs |
Q30580057 | Behavioral effects of cocaine mediated by nitric oxide-GAPDH transcriptional signaling |
Q27654242 | Binding of an octylglucoside detergent molecule in the second substrate (S2) site of LeuT establishes an inhibitor-bound conformation |
Q40905109 | Characterization of the 5'-flanking region of the human dopamine transporter gene |
Q33733368 | Chronic exposure to manganese alters brain responses to amphetamine: a pharmacological magnetic resonance imaging study |
Q35602687 | Cocaine decreases saccharin preference without altering sweet taste sensitivity |
Q104795227 | Cocaine-induced locomotor stimulation involves autophagic degradation of the dopamine transporter |
Q37386620 | Communication networks in the brain: neurons, receptors, neurotransmitters, and alcohol |
Q24656589 | Comparative molecular field analysis using selectivity fields reveals residues in the third transmembrane helix of the serotonin transporter associated with substrate and antagonist recognition |
Q21262013 | Comparison of the monoamine transporters from human and mouse in their sensitivities to psychostimulant drugs |
Q55333423 | Competition between Li+ and Na+ in sodium transporters and receptors: Which Na+-Binding sites are "therapeutic" Li+ targets? |
Q27320918 | Complete mapping of substrate translocation highlights the role of LeuT N-terminal segment in regulating transport cycle |
Q33758304 | Conformational changes in dopamine transporter intracellular regions upon cocaine binding and dopamine translocation |
Q33729757 | Conformational dynamics of ligand-dependent alternating access in LeuT. |
Q44100871 | Consequences of maternal cocaine on cerebral microvascular functions in piglets. |
Q33894614 | Could a common biochemical mechanism underlie addictions? |
Q29616590 | Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters |
Q37614269 | Crystal structures of all-alpha type membrane proteins |
Q33738102 | Design, Synthesis and Interaction at the Vesicular Monoamine Transporter-2 of Lobeline Analogs: Potential Pharmacotherapies for the Treatment of Psychostimulant Abuse |
Q61135975 | Designing a norepinephrine optical tracer for imaging individual noradrenergic synapses and their activity in vivo |
Q52648128 | Development of serotonin transporter reuptake inhibition assays using JAR cells. |
Q38819648 | Differential effects of the tricyclic antidepressant amoxapine on glycine uptake mediated by the recombinant GLYT1 and GLYT2 glycine transporters. |
Q43542096 | Differential sensitivity to NaCl for inhibitors and substrates that recognize mutually exclusive binding sites on the neuronal transporter of dopamine in rat striatal membranes |
Q44262082 | Differential serotonergic inhibition of in vitro striatal [3H]acetylcholine release in prenatally cocaine-exposed male and female rats |
Q33194408 | Distinct Molecular Recognition of Psychostimulants by Human andDrosophilaSerotonin Transporters |
Q42439159 | Dopamine transporter endocytic determinants: carboxy terminal residues critical for basal and PKC-stimulated internalization. |
Q37023778 | Dopamine transporter mutant mice in experimental neuropharmacology |
Q40864474 | Dopamine uptake by mouse neuroblastoma N1E-115 cells stably expressing human dopamine transporter is differentially inhibited by anti-idiotypic ab2beta antibodies mimicking the configuration of cocaine |
Q24815335 | Dopamine-independent locomotor actions of amphetamines in a novel acute mouse model of Parkinson disease |
Q37009426 | Drugs of abuse and human placenta |
Q35029584 | Drugs, flies, and videotape: the effects of ethanol and cocaine on Drosophila locomotion |
Q24647786 | Dual dopamine/serotonin releasers as potential medications for stimulant and alcohol addictions |
Q24641896 | Dual dopamine/serotonin releasers: potential treatment agents for stimulant addiction |
Q35965902 | Eating high fat chow decreases dopamine clearance in adolescent and adult male rats but selectively enhances the locomotor stimulating effects of cocaine in adolescents |
Q48178608 | Eating high fat chow enhances the locomotor-stimulating effects of cocaine in adolescent and adult female rats |
Q47566777 | Effect of Dimerization on the Dynamics of Neurotransmitter:Sodium Symporters. |
Q41510296 | Effect of acute millimeter wave exposure on dopamine metabolism of NGF-treated PC12 cells |
Q54364129 | Effects of co-administration of the GABAB receptor agonist baclofen and a positive allosteric modulator of the GABAB receptor, CGP7930, on the development and expression of amphetamine-induced locomotor sensitization in rats. |
Q42131731 | Effects of methamphetamine on single unit activity in rat medial prefrontal cortex in vivo |
Q44683375 | Effects of serotonin (5-HT)1B receptor ligands on amphetamine-seeking behavior in rats |
Q35741014 | Electrophysiological properties of catecholaminergic neurons in the norepinephrine-deficient mouse |
Q43966743 | Enantioselective synthesis of S-(+)-2beta-carboalkoxy-3alpha-[bis(4-fluorophenyl)methoxy]tropanes as novel probes for the dopamine transporter |
Q36326990 | Energy landscape of LeuT from molecular simulations |
Q35094105 | From genes to integrative physiology: ion channel and transporter biology in Caenorhabditis elegans |
Q24291215 | Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1 |
Q36967668 | Functional internal complexity of amygdala: focus on gene activity mapping after behavioral training and drugs of abuse |
Q40725346 | Functional significance of a highly conserved glutamate residue of the human noradrenaline transporter |
Q47624474 | Gβγ subunit activation promotes dopamine efflux through the dopamine transporter |
Q50072495 | Heterogeneities in Axonal Structure and Transporter Distribution Lower Dopamine Reuptake Efficiency. |
Q28469327 | Hypoinsulinemia regulates amphetamine-induced reverse transport of dopamine |
Q35234897 | Identification of a novel selective serotonin reuptake inhibitor by coupling monoamine transporter-based virtual screening and rational molecular hybridization |
Q44823902 | In vivo evidence that genetic background controls impulse-dependent dopamine release induced by amphetamine in the nucleus accumbens. |
Q48421523 | Increased occupancy of dopamine receptors in human striatum during cue-elicited cocaine craving |
Q31880529 | Individual and combined effects of ethanol and cocaine on the human dopamine transporter in neuronal cell lines |
Q33531756 | Insertion of tetracysteine motifs into dopamine transporter extracellular domains |
Q40803358 | Insights into the Modulation of Dopamine Transporter Function by Amphetamine, Orphenadrine, and Cocaine Binding |
Q37226701 | Interaction of catechol and non-catechol substrates with externally or internally facing dopamine transporters |
Q35017258 | Interaction of tyrosine 151 in norepinephrine transporter with the 2β group of cocaine analog RTI-113. |
Q93078709 | Involvement of CB2 Receptors in the Neurobehavioral Effects of Catha Edulis (Vahl) Endl. (Khat) in Mice |
Q34121740 | Ion/substrate-dependent conformational dynamics of a bacterial homolog of neurotransmitter:sodium symporters. |
Q36754967 | Mechanism of Paroxetine (Paxil) Inhibition of the Serotonin Transporter. |
Q27334784 | Membrane potential shapes regulation of dopamine transporter trafficking at the plasma membrane |
Q43640134 | Methamphetamine increases expression of the apoptotic c-myc and L-myc genes in the mouse brain. |
Q34801642 | Microseconds simulations reveal a new sodium-binding site and the mechanism of sodium-coupled substrate uptake by LeuT |
Q32133977 | Modulation of the neuronal dopamine transporter activity by the metabotropic glutamate receptor mGluR5 in rat striatal synaptosomes through phosphorylation mediated processes |
Q40415118 | Molecular Mechanism of Dopamine Transport by Human Dopamine Transporter |
Q34228641 | Molecular mechanisms of neurotransmitter release |
Q91595356 | Monoamine transporters: structure, intrinsic dynamics and allosteric regulation |
Q35581532 | Na+ and the substrate permeation pathway in dopamine transporters |
Q42489747 | Neurochemical changes in brain serotonin neurons in immature and adult offspring prenatally exposed to cocaine |
Q42719386 | Neurotransmitter/sodium symporter orthologue LeuT has a single high-affinity substrate site |
Q46937479 | Nicotine increases dopamine clearance in medial prefrontal cortex in rats raised in an enriched environment |
Q37004113 | Nonclassical, distinct endocytic signals dictate constitutive and PKC-regulated neurotransmitter transporter internalization |
Q24554381 | Norepinephrine transporter inhibitors and their therapeutic potential |
Q40690434 | Oligomerization and trafficking of the human dopamine transporter. Mutational analysis identifies critical domains important for the functional expression of the transporter |
Q36653973 | On the effects of psychostimulants, antidepressants, and the antiparkinsonian drug levodopa on dopamine neurons. |
Q34416206 | PICKing on transporters |
Q43819039 | Pharmacological characterisation of (E)-N-(3-iodoprop-2-enyl)-2beta-carbomethoxy-3beta-(4'-methylphenyl)nortropane (PE2I) binding to the rat neuronal dopamine transporter expressed in COS cells |
Q28594026 | Physical and functional interaction between the dopamine transporter and the synaptic vesicle protein synaptogyrin-3 |
Q22251021 | Plasma membrane monoamine transporters: structure, regulation and function |
Q43700720 | Plasmalemmal mu-opioid receptor distribution mainly in nondopaminergic neurons in the rat ventral tegmental area |
Q37583405 | Polymorphism of the COMT, MAO, DAT, NET and 5-HTT Genes, and Biogenic Amines in Parkinson's Disease |
Q34811630 | Probes for the dopamine transporter: new leads toward a cocaine-abuse therapeutic--A focus on analogues of benztropine and rimcazole |
Q47302876 | Quantitative Assessment of the Energetics of Dopamine Translocation by Human Dopamine Transporter |
Q42054718 | Recognition properties and competitive assays of a dual dopamine/serotonin selective molecularly imprinted polymer |
Q42933604 | Role of aberrant striatal dopamine D1 receptor/cAMP/protein kinase A/DARPP32 signaling in the paradoxical calming effect of amphetamine |
Q33868543 | Role of the serotonergic system in reduced pulmonary function after exposure to methamphetamine |
Q34188761 | Rotating disk electrode voltammetric measurements of serotonin transporter kinetics in synaptosomes |
Q42283745 | S(+)amphetamine induces a persistent leak in the human dopamine transporter: molecular stent hypothesis |
Q34649517 | SLC6 transporters: structure, function, regulation, disease association and therapeutics |
Q34117810 | Serotonin releasing agents. Neurochemical, therapeutic and adverse effects |
Q35871448 | Simulating the distance distribution between spin-labels attached to proteins |
Q47321062 | Single-Shot Detection of Neurotransmitters in Whole-Blood Samples by Means of the Heat-Transfer Method in Combination with Synthetic Receptors |
Q34130830 | Single-molecule dynamics of gating in a neurotransmitter transporter homologue |
Q42689431 | State-dependent conformations of the translocation pathway in the tyrosine transporter Tyt1, a novel neurotransmitter:sodium symporter from Fusobacterium nucleatum. |
Q45008225 | Structural analysis of dopamine- and amphetamine-induced depolarization currents in the human dopamine transporter. |
Q34061069 | Structure and function of the dopamine transporter |
Q27676749 | Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context |
Q27670914 | Substrate binds in the S1 site of the F253A mutant of LeuT, a neurotransmitter sodium symporter homologue |
Q33600236 | Substrate-dependent proton antiport in neurotransmitter:sodium symporters |
Q35227331 | Substrate-modulated gating dynamics in a Na+-coupled neurotransmitter transporter homologue |
Q44593701 | Synthesis and pharmacological evaluation of ( Z )-9-(Heteroarylmethylene)-7-azatricyclo[4.3.1.0 3,7 ]decanes: thiophene analogues as potent norepinephrine transporter inhibitors |
Q92034249 | The allosteric mechanism of substrate-specific transport in SLC6 is mediated by a volumetric sensor |
Q36781347 | The cost of living in the membrane: a case study of hydrophobic mismatch for the multi-segment protein LeuT. |
Q21091097 | The dopamine metabolite 3-methoxytyramine is a neuromodulator |
Q37004117 | The dopamine transporter constitutively internalizes and recycles in a protein kinase C-regulated manner in stably transfected PC12 cell lines. |
Q40764395 | The dopamine transporter gene (SLC6A3) variable number of tandem repeats domain enhances transcription in dopamine neurons |
Q35012764 | The functioning neuronal transporter for dopamine: kinetic mechanisms and effects of amphetamines, cocaine and methylphenidate. |
Q34435130 | The human dopamine transporter gene: gene organization, transcriptional regulation, and potential involvement in neuropsychiatric disorders |
Q42909481 | The mechanism of a neurotransmitter:sodium symporter--inward release of Na+ and substrate is triggered by substrate in a second binding site |
Q24304470 | The multiple LIM domain-containing adaptor protein Hic-5 synaptically colocalizes and interacts with the dopamine transporter |
Q40804815 | The role of conserved tryptophan and acidic residues in the human dopamine transporter as characterized by site-directed mutagenesis |
Q34142899 | Therapeutic and adverse actions of serotonin transporter substrates |
Q24648659 | Trace amine-associated receptor 1-Family archetype or iconoclast? |
Q37315212 | Transition metal ion FRET uncovers K(+) regulation of a neurotransmitter/sodium symporter. |
Q24658095 | Unfaithful neurotransmitter transporters: focus on serotonin uptake and implications for antidepressant efficacy |
Q24647764 | Vesicular monoamine transporter 2: role as a novel target for drug development |
Q42321747 | WAVE1 in neurons expressing the D1 dopamine receptor regulates cellular and behavioral actions of cocaine |
Q35581536 | What can be learned from studies of multisubstrate mechanisms of neuronal dopamine transport? |
Q27676655 | X-ray structures of LeuT in substrate-free outward-open and apo inward-open states |
Q43653057 | [3H]MFZ 2-12: a novel radioligand for the dopamine transporter. |