'Ischemic tolerance' phenomenon found in the brain

scientific article published in September 1990

'Ischemic tolerance' phenomenon found in the brain is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/0006-8993(90)90189-I
P698PubMed publication ID2245337

P2093author name stringR Fukunaga
M Matsumoto
H Ueda
N Handa
K Kimura
K Mikoshiba
K Kitagawa
M Niinobe
M Tagaya
R Hata
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)21-24
P577publication date1990-09-01
P1433published inBrain ResearchQ4955782
P1476title'Ischemic tolerance' phenomenon found in the brain
P478volume528

Reverse relations

cites work (P2860)
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Q427544011-Methyl-1,2,3,4-tetrahydroisoquinoline and established uncompetitive NMDA receptor antagonists induce tolerance to excitotoxicity.
Q3775201514-3-3gamma and neuroglobin are new intrinsic protective factors for cerebral ischemia
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Q33984045Adaptation to chronic MG132 reduces oxidative toxicity by a CuZnSOD-dependent mechanism
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Q57405390Adenosine A3 receptors and viability of astrocytes
Q43698294Adenosine receptor antagonists cancelled the ischemic tolerance phenomenon in gerbil
Q33916931Adenosine, the imperfect endogenous anti-ischemic cardio-neuroprotector
Q45069718Administration of 5-methoxyindole-2-carboxylic acid that potentially targets mitochondrial dihydrolipoamide dehydrogenase confers cerebral preconditioning against ischemic stroke injury
Q37278544Age-related reduction of cerebral ischemic preconditioning: myth or reality?
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Q48273885Blood as the carrier of ischemic tolerance in rat brain.
Q48464199Blood cells serve as a source of factor-inducing rapid ischemic tolerance in brain
Q43595514Both caspase-dependent and caspase-independent pathways may be involved in hippocampal CA1 neuronal death because of loss of cytochrome c From mitochondria in a rat forebrain ischemia model
Q33180204Bradykinin mediates cardiac preconditioning at a distance
Q57405388Brain Adenosine Receptors as Targets for Therapeutic Intervention in Neurodegenerative Diseases
Q48530031Brain genomic response following hypoxia and re-oxygenation in the neonatal rat. Identification of genes that might contribute to hypoxia-induced ischemic tolerance
Q54108837Brain ischemic preconditioning protects against ischemic injury and preserves the blood-brain barrier via oxidative signaling and Nrf2 activation.
Q37270099Brain tissue responses to ischemia
Q43263233Brief, repeated, oxygen-glucose deprivation episodes protect neurotransmission from a longer ischemic episode in the in vitro hippocampus: role of adenosine receptors
Q28306019CREB and cAMP response element-mediated gene expression in the ischemic brain
Q37355246CaMKII in cerebral ischemia
Q48936730Calcium movement in ischemia-tolerant hippocampal CA1 neurons after transient forebrain ischemia in gerbils
Q48377151Calpain-induced proteolysis after transient global cerebral ischemia and ischemic tolerance in a rat model
Q41004172Cardioprotection by organs in stress or distress
Q34470616Caspase 3 activation is essential for neuroprotection in preconditioning
Q48503436Ceftriaxone modulates uptake activity of glial glutamate transporter-1 against global brain ischemia in rats
Q43570501Cell permeable exogenous ceramide reduces infarct size in spontaneously hypertensive rats supporting in vitro studies that have implicated ceramide in induction of tolerance to ischemia
Q41068397Cell stress genes and neuronal protection
Q37179243Cellular and molecular neurobiology of brain preconditioning
Q38529630Cerebral Ischemic Preconditioning: the Road So Far….
Q42519354Cerebral glucose utilization in transgenic mice overexpressing heat shock protein 70 is altered by dizocilpine
Q49021037Cerebral ischemic pre-conditioning enhances the binding characteristics and glutamate uptake of glial glutamate transporter-1 in hippocampal CA1 subfield of rats
Q42455983Cerebral ischemic preconditioning reduces glutamate excitotoxicity by up-regulating the uptake activity of GLT-1 in rats
Q48337442Cerebrovascular protection by sequential bilateral carotid artery ligation in aged spontaneously hypertensive rats
Q34569580Changes in HSP gene and protein expression in natural scrapie with brain damage
Q43658921Changes in gene expression following induction of ischemic tolerance in rat brain: detection and verification
Q48278407Changes in protein tyrosine phosphorylation in the rat brain after cerebral ischemia in a model of ischemic tolerance
Q26752592Chemical Conditioning as an Approach to Ischemic Stroke Tolerance: Mitochondria as the Target
Q31888925Chemical preconditioning in mice is not mediated by upregulation of nitric oxide synthase isoforms
Q44574724Chemical preconditioning prevents paradoxical increase in glutamate release during ischemia by activating ATP-dependent potassium channels in gerbil hippocampus
Q48623358Chemical preconditioning: a cytoprotective strategy
Q34179036Cholesteryl Glucoside Stimulates Activation of Protein Kinase B/Akt in the Motor Neuron-Derived NSC34 Cell Line
Q36249972Cholinergic treatment: what are the early neuropathological targets?
Q38169985Clinical application of preconditioning and postconditioning to achieve neuroprotection.
Q40825269Comparative analysis of autophagy and tauopathy related markers in cerebral ischemia and Alzheimer's disease animal models
Q46347087Comparison of Hyperemic Impedance Echocardiography with Dobutamine Stress Echocardiography to Detect Inducible Myocardial Ischemia: A Pilot Study
Q42456842Competing processes of cell death and recovery of function following ischemic preconditioning
Q58131545Conditioning Against the Pathology of Parkinson's disease
Q31875032Consolidation of transient ionotropic glutamate signals through nuclear transcription factors in the brain.
Q48384154Cortical spreading depression activates trophic factor expression in neurons and astrocytes and protects against subsequent focal brain ischemia
Q48629246Cortical spreading depression induces long-term alterations of BDNF levels in cortex and hippocampus distinct from lesion effects: implications for ischemic tolerance
Q46094742Cortical spreading depression preconditioning mediates neuroprotection against ischemic stroke by inducing AMP-activated protein kinase-dependent autophagy in a rat cerebral ischemic/reperfusion injury model
Q34976390Critical mechanisms of secondary damage after inflicted head injury in infants and children
Q48479682Cryptic expression of the 70-kDa heat shock protein, hsp72, in gerbil hippocampus after transient ischemia
Q26777973Current insights into the molecular mechanisms of hypoxic pre- and postconditioning using hypobaric hypoxia
Q43543765Decreased epileptic susceptibility correlates with neuropeptide Y overexpression in a model of tolerance to excitotoxicity
Q48259729Delayed induction of JunB precedes CA1 neuronal death after global ischemia in the gerbil
Q48585547Delayed postconditionig initiates additive mechanism necessary for survival of selectively vulnerable neurons after transient ischemia in rat brain
Q36675806Delayed tolerance with repetitive transient focal ischemic preconditioning in the mouse
Q40993382Delivery of a constitutively active form of the heat shock factor using a virus vector protects neuronal cells from thermal or ischaemic stress but not from apoptosis
Q43970038Desferrioxamine induces delayed tolerance against cerebral ischemia in vivo and in vitro
Q52564103Diazoxide inhibits of ER stress‑mediated apoptosis during oxygen‑glucose deprivation in vitro and cerebral ischemia‑reperfusion in vivo.
Q46164224Diethyl dithiocarbamic acid, a possible nuclear factor kappa B inhibitor, attenuates ischemic postconditioning-induced attenuation of cerebral ischemia-reperfusion injury in mice
Q51403268Differences in brain oxygenation between two sequential cardiac arrests during axillobifemoral bypass in a Stanford type A dissecting aneurysm.
Q61807848Differential role of nitric oxide pathway and heat shock protein in preconditioning and lipopolysaccharide-induced brain ischemic tolerance
Q73571730Diphosphorylation of extracellular signal-regulated kinases and c-Jun N-terminal protein kinases in brain ischemic tolerance in rat
Q51025363Disruption of KV2.1 somato-dendritic clusters prevents the apoptogenic increase of potassium currents.
Q40740530Distribution of 72-kDa heat-shock protein in rat brain after hyperthermia
Q45282255Does permanent carotid artery occlusion produce a 'preconditioning-like' effect towards more severe hypotension in energy metabolites? Role of cerebral adenosine
Q43710056Downregulation of nitric oxide in the brain of mice during their hypoxic preconditioning
Q48518347Early electrocortical changes consistent with ischemic preconditioning in rat.
Q48371574Early recovery of protein synthesis following ischemia in hippocampal neurons with induced tolerance in the gerbil
Q30900110Early-onset tolerance in rat global cerebral ischemia induced by a mitochondrial inhibitor
Q48331090Effect of cortical spreading depression on the levels of mRNA coding for putative neuroprotective proteins in rat brain
Q44616792Effect of inherent epileptic seizures on brain injury after transient cerebral ischemia in Mongolian gerbils
Q37110672Effect of ischemic preconditioning on the expression of c-myb in the CA1 region of the gerbil hippocampus after ischemia/reperfusion injury
Q48556658Effect of ischemic preconditioning on the expression of putative neuroprotective genes in the rat brain
Q46086096Effect of noradrenalin and EGb 761 pretreatment on the ischemia-reperfusion injured spinal cord neurons in rabbits
Q45058369Effect of pharmacologic preconditioning with tetrandrine on subsequent ischemia/reperfusion injury in rat liver
Q48271051Effect of seizures on cerebral hypoxic-ischemic lesions in immature rats
Q48720581Effect of spinal cord preconditioning on paraplegia during cross-clamping of the thoracic aorta
Q33256562Effect of sublethal 6-hydroxydopamine on the response to subsequent oxidative stress in dopaminergic cells: evidence for preconditioning
Q46667497Effect of the first window of ischemic preconditioning on mitochondrial dysfunction following global cerebral ischemia
Q37195575Effects of cerebral ischemia on neuronal hemoglobin
Q42347140Effects of ischemic preconditioning on PDGF-BB expression in the gerbil hippocampal CA1 region following transient cerebral ischemia
Q48658222Effects of ischemic preconditioning on blood-brain barrier permeability and MMP-9 expression of ischemic brain
Q48480064Effects of ischemic tolerance on mRNA levels of IP3R1, beta-actin, and neuron-specific enolase in hippocampal CA1 area of the gerbil brain
Q48592076Effects of oxidative stress on the expression of limbic-specific protease neuropsin and avoidance learning in mice
Q39814082Electrophysiology of cerebral ischemia and reperfusion: First evidence for the role of synapse in ischemic tolerance.
Q47141323Endogenous Agmatine Induced by Ischemic Preconditioning Regulates Ischemic Tolerance Following Cerebral Ischemia
Q34286604Endothelial nitric oxide synthase transgenic models of endothelial dysfunction
Q58777893Enhancing and Extending Biological Performance and Resilience
Q42664414Environmental enrichment enhances recovery of function but exacerbates ischemic cell death.
Q34995143Epsilon PKC increases brain mitochondrial SIRT1 protein levels via heat shock protein 90 following ischemic preconditioning in rats
Q44924589Epsilon protein kinase C mediated ischemic tolerance requires activation of the extracellular regulated kinase pathway in the organotypic hippocampal slice
Q28575710Erythropoietin is a paracrine mediator of ischemic tolerance in the brain: evidence from an in vitro model
Q28566249Essential role of the redox-sensitive kinase p66shc in determining energetic and oxidative status and cell fate in neuronal preconditioning
Q43885962Evaluation of preconditioning treatments to protect near-pure cortical neuronal cultures from in vitro ischemia induced acute and delayed neuronal death
Q46421666Evidence for the role of histaminergic pathways in neuroprotective mechanism of ischemic postconditioning in mice
Q48215599Evidence from cultured rat cortical neurons of differences in the mechanism of ischemic preconditioning of brain and heart
Q46848436Evolving possible link between PI3K and NO pathways in neuroprotective mechanism of ischemic postconditioning in mice
Q57798084Experimental Designs for Repeated Mild Traumatic Brain Injury: Challenges and Considerations
Q44097741Expression of 150-kd oxygen-regulated protein in the hippocampus suppresses delayed neuronal cell death
Q41040050Expression of an ADP-ribosylation factor like gene, ARF4L, is induced after transient forebrain ischemia in the gerbil
Q48874700Expression of early gene proteins, structural changes in brain neurons in hypobaric hypoxia, and the correcting effects of preconditioning
Q73466558Extended neuronal protection induced after sublethal ischemia adjacent to the area with delayed neuronal death
Q48839313Focal cerebral ischaemia increases the levels of several classes of heat shock proteins and their corresponding mRNAs
Q26825167From rapid to delayed and remote postconditioning: the evolving concept of ischemic postconditioning in brain ischemia
Q46808223Functional significance of the preconditioning-induced down-regulation of glutamate transporter GLT-1 in neuron/astrocyte co-cultures
Q37226935GABA synapses mediate neuroprotection after ischemic and epsilonPKC preconditioning in rat hippocampal slice cultures.
Q46556382Geldanamycin protects rat brain through overexpression of HSP70 and reducing brain edema after cerebral focal ischemia.
Q43947451Gender-dependent hypoxic tolerance mediated via gender-specific mechanisms
Q48587981Gene expression analysis to identify molecular correlates of pre- and post-conditioning derived neuroprotection
Q33269892Gene expression changes after seizure preconditioning in the three major hippocampal cell layers
Q34692253Global and ocular hypothermic preconditioning protect the rat retina from ischemic damage
Q48766567HSP70 protects murine astrocytes from glucose deprivation injury
Q48619957Heat shock protects cultured neurons from glutamate toxicity
Q35246221Heat shock proteins in hypoxic-ischemic brain injury: a perspective
Q40648790Heat shock response in the central nervous system
Q38808589Help-me signaling: Non-cell autonomous mechanisms of neuroprotection and neurorecovery
Q33744388Heptanol triggers cardioprotection via mitochondrial mechanisms and mitochondrial potassium channel opening in rat hearts.
Q48328606Hilar somatostatin neurons are more vulnerable to an ischemic insult than CA1 pyramidal neurons
Q26801660Histone Deacetylases Exert Class-Specific Roles in Conditioning the Brain and Heart Against Acute Ischemic Injury
Q40796472HspB5/αB-crystallin increases dendritic complexity and protects the dendritic arbor during heat shock in cultured rat hippocampal neurons
Q36697362Hurdles to clear before clinical translation of ischemic postconditioning against stroke
Q35939346Hydrogen sulfide preconditioning or neutrophil depletion attenuates ischemia-reperfusion-induced mitochondrial dysfunction in rat small intestine
Q48726546Hyperthermia-induced neuronal protection against ischemic injury in gerbils
Q48226262Hypobaric hypoxia affects rat behavior and immediate early gene expression in the brain: the corrective effect of preconditioning
Q57100088Hypobaric hypoxia preconditioning attenuates acute lung injury during high-altitude exposure in rats via up-regulating heat-shock protein 70
Q30304687Hypothermia-induced ischemic tolerance
Q30310894Hypothermic preconditioning induces rapid tolerance to focal ischemic injury in the rat.
Q48228110Hypoxia preconditioning attenuates brain edema associated with kainic acid-induced status epilepticus in rats
Q37667292Hypoxia-Inducible Factor-1α Target Genes Contribute to Retinal Neuroprotection
Q37236104Hypoxia-ischemia and retinal ganglion cell damage
Q35765535Hypoxic Conditioning as a New Therapeutic Modality
Q47837079Hypoxic preconditioning improves spatial cognitive ability in mice
Q38012631Hypoxic preconditioning in an autohypoxic animal model
Q44092218Hypoxic tolerance induction in rat brain slices following hypoxic preconditioning due to expression of neuroprotective proteins as revealed by dynamic changes in glucose metabolism
Q48365921Hypoxic-ischemic tolerance phenomenon observed in neonatal rat brain
Q37347684Immediate neuronal preconditioning by NS1619.
Q27022067Immune mechanisms in cerebral ischemic tolerance
Q72403409Immunohistochemical investigation of hypoxic/ischemic brain damage in forensic autopsy cases
Q54185872Immunohistochemical localization of superoxide dismutase in the hippocampus following ischemia in a gerbil model of ischemic tolerance.
Q46692712Implication of mast cell degranulation in ischemic preconditioning-induced prevention of cerebral injury
Q34763983Implications for neuroprotective treatments
Q44176768Improvement in neuronal survival after ischemic preconditioning in hippocampal slice cultures
Q44762664In vitro ischemic tolerance involves upregulation of glutamate transport partly mediated by the TACE/ADAM17-tumor necrosis factor-alpha pathway.
Q48777299Increased hypoxic tolerance by chemical inhibition of oxidative phosphorylation: "chemical preconditioning".
Q48273820Increased intracellular Ca2+ concentration in the hippocampal CA1 area during global ischemia and reperfusion in the rat: a possible cause of delayed neuronal death
Q48219630Increased membrane/nuclear translocation and phosphorylation of p90 KD ribosomal S6 kinase in the brain of hypoxic preconditioned mice
Q51407166Increased neuronal excitability after long-term O(2) deprivation is mediated mainly by sodium channels.
Q48738005Increased phosphorylation of Ets-like transcription factor-1 in neurons of hypoxic preconditioned mice
Q41860972Increased potassium conductance of brain mitochondria induces resistance to permeability transition by enhancing matrix volume
Q48109538Induced hippocampal neuron protection in an optimized gerbil ischemia model: insult thresholds for tolerance induction and altered gene expression defined by ischemic depolarization
Q48783691Induced tolerance to ischemia in gerbil hippocampal neurons
Q46665955Induction of 70-kDa heat shock protein and hsp70 mRNA following transient focal cerebral ischemia in the rat.
Q71853262Induction of Jun-like immunoreactivity in astrocytes in gerbil hippocampus with ischemic tolerance
Q48087514Induction of NADPH-diaphorase activity in the hippocampus in a rat model of cerebral ischemia and ischemic tolerance
Q48094747Induction of ischemic tolerance following brief focal ischemia in rat brain
Q43660771Induction of the HSP110/105 family in the rat hippocampus in cerebral ischemia and ischemic tolerance.
Q41604229Induction of tolerance in rat cortical neurons: hypoxic preconditioning.
Q30924987Infarct tolerance accompanied enhanced BDNF-like immunoreactivity in neuronal nuclei
Q32082619Infarct tolerance against temporary focal ischemia following spreading depression in rat brain
Q38978527Inflammation and Stroke: An Overview
Q35012464Inhalative preconditioning with hydrogen sulfide attenuated apoptosis after retinal ischemia/reperfusion injury.
Q48121175Inhibition of caspase-9 activation and apoptosis is involved in ischemic preconditioning-induced neuroprotection in rat brain
Q34068989Inhibition of prolyl hydroxylases by dimethyloxaloylglycine after stroke reduces ischemic brain injury and requires hypoxia inducible factor-1α.
Q35951508Inhibition of toll-like receptor and cytokine signaling--a unifying theme in ischemic tolerance
Q48882811Interleukin-1 mediates induction of tolerance to global ischemia in gerbil hippocampal CA1 neurons
Q82468426Intermittent hypobaric hypoxia preconditioning induced brain ischemic tolerance by up-regulating glial glutamate transporter-1 in rats
Q52540813Involvement of intracellular regulatory systems in the adaptive effects of transient anoxia in vitro.
Q43540608Is the AMPA receptor subunit GluR2 mRNA an early indicator of cell fate after ischemia? A quantitative single cell RT-PCR study
Q37755882Is there a future for neuroprotective agents in cardiac surgery?
Q33919637Is there a place for cerebral preconditioning in the clinic?
Q73118832Ischaemic pre-conditioning in organotypic hippocampal slice cultures is inversely correlated to the induction of the 72 kDa heat shock protein (HSP72)
Q48876432Ischaemic preconditioning in the rat brain: a longitudinal magnetic resonance imaging (MRI) study
Q35753366Ischaemic preconditioning: therapeutic implications for stroke?
Q91710126Ischemia-Triggered Glutamate Excitotoxicity From the Perspective of Glial Cells
Q73212370Ischemic "cross" tolerance in hypoxic ischemia of immature rat brain
Q29394624Ischemic Postconditioning as a Novel Avenue to Protect against Brain Injury after Stroke
Q39292994Ischemic Preconditioning in the Intensive Care Unit
Q46299827Ischemic Tolerance of the Brain and Spinal Cord: A Review.
Q64052647Ischemic postconditioning prevents surge of presynaptic glutamate release by activating mitochondrial ATP-dependent potassium channels in the mouse hippocampus
Q48730759Ischemic pre-conditioning affects the subcellular distribution of protein kinase C and calcium/calmodulin-dependent protein kinase II in the gerbil hippocampal CA1 neurons
Q34013329Ischemic preconditioning acts upstream of GluR2 down-regulation to afford neuroprotection in the hippocampal CA1
Q48144600Ischemic preconditioning attenuates of ischemia-induced degradation of spectrin and tau: implications for ischemic tolerance
Q46449655Ischemic preconditioning procedure induces behavioral deficits in the absence of brain injury?
Q73589459Ischemic preconditioning protects against paraplegia after transient aortic occlusion in the rat
Q48098412Ischemic preconditioning reduces peripheral oxidative damage associated with brain ischemia in rats.
Q46492192Ischemic preconditioning to prevent lethal ischemic spinal cord injury in a swine model
Q41954356Ischemic preconditioning-induced neuroprotection is associated with differential expression of IL-1beta and IL-1 receptor antagonist in the ischemic cortex.
Q48682213Ischemic preconditioning: a long term survival study using behavioural and histological endpoints
Q48558808Ischemic preconditioning: a novel target for neuroprotective therapy
Q35126696Ischemic tolerance and endogenous neuroprotection
Q37268106Ischemic tolerance as an active and intrinsic neuroprotective mechanism
Q48618934Ischemic tolerance in hippocampal CA1 neurons studied using contralateral controls
Q48281088Ischemic tolerance in murine cortical cell culture: critical role for NMDA receptors
Q37981130Ischemic tolerance in the brain: endogenous adaptive machinery against ischemic stress
Q46229505Isoflurane exerts a short-term but not a long-term preconditioning effect in neonatal rats exposed to a hypoxic-ischaemic neuronal injury
Q37678152Isometric Exercise Training for Managing Vascular Risk Factors in Mild Cognitive Impairment and Alzheimer's Disease
Q73247340K(ATP) channel openers, adenosine agonists and epileptic preconditioning are stress signals inducing hippocampal neuroprotection
Q33896931Killer proteases and little strokes--how the things that do not kill you make you stronger
Q43596404Late preconditioning in rat retina: involvement of adenosine and ATP-sensitive K(+) channel
Q73276362Lethal forebrain ischemia stimulates sphingomyelin hydrolysis and ceramide generation in the gerbil hippocampus
Q36835509Ligation of lateral carotid artery attenuates disturbance of brain function caused by subsequent cerebral ischemia in rabbits
Q41481378Limb remote-preconditioning protects against focal ischemia in rats and contradicts the dogma of therapeutic time windows for preconditioning
Q43548448Lipopolysaccharide-induced ischemic tolerance is associated with increased levels of ceramide in brain and in plasma
Q35705851Lipopolysaccharide-induced microglial activation and neuroprotection against experimental brain injury is independent of hematogenous TLR4
Q35214699Liver ischemic preconditioning: a new strategy for the prevention of ischemia-reperfusion injury
Q48878720Long-lasting neuroprotective effect of sildenafil against 3,4-methylenedioxymethamphetamine- induced 5-hydroxytryptamine deficits in the rat brain.
Q50061129Long-term depression induced by endogenous cannabinoids produces neuroprotection via astroglial CB1R after stroke in rodents
Q36625579Mechanisms of neuroprotection during ischemic preconditioning: lessons from anoxic tolerance
Q35120144Mechanisms, challenges and opportunities in stroke
Q37227909Metabolic downregulation: a key to successful neuroprotection?
Q47822392Methods to detect hypoxia-induced ischemic tolerance in the brain.
Q38711083MicroRNA Changes in Preconditioning-Induced Neuroprotection
Q43589250Microglia/macrophages proliferate in striatum and neocortex but not in hippocampus after brief global ischemia that produces ischemic tolerance in gerbil brain
Q48522340Mild preconditioning hypoxia modifies nerve growth factor-induced gene A messenger RNA expression in the rat brain induced by severe hypoxia
Q34408217Mitogen-activated protein kinases and cerebral ischemia
Q41643072Modulation of apoptosis by adenosine in the central nervous system: a possible role for the A3 receptor. Pathophysiological significance and therapeutic implications for neurodegenerative disorders
Q28565694Molecular cloning of a novel member of the HSP110 family of genes, ischemia-responsive protein 94 kDa (irp94), expressed in rat brain after transient forebrain ischemia
Q37056974Molecular physiology of preconditioning-induced brain tolerance to ischemia
Q33304630Mutant huntingtin can paradoxically protect neurons from death
Q35174569N-methyl-D-aspartate and TrkB receptor activation in cerebellar granule cells: an in vitro model of preconditioning to stimulate intrinsic survival pathways in neurons
Q33792964N-methyl-D-aspartate and TrkB receptors protect neurons against glutamate excitotoxicity through an extracellular signal-regulated kinase pathway
Q59265517NO-induced neuroprotection in ischemic preconditioning stimulates mitochondrial Mn-SOD activity and expression via RAS/ERK1/2 pathway
Q48318714Negative Feedback Regulation of Raf/MEK/ERK Cascade After Sublethal Cerebral Ischemia in the Rat Hippocampus
Q41707869Neurobiology of stroke.
Q48351353Neuronal stress and injury in C57/BL mice after systemic kainic acid administration
Q54642083Neuroprotection Induced In Vitro by Ischemic Preconditioning and Postconditioning: Modulation of Apoptosis and PI3K–Akt Pathways
Q44085160Neuroprotection by hypoxic preconditioning requires sequential activation of vascular endothelial growth factor receptor and Akt.
Q48108690Neuroprotective effect of WIN 55,212-2 pretreatment against focal cerebral ischemia through activation of extracellular signal-regulated kinases in rats
Q52603043Neuroprotective effect of ischemic postconditioning on sciatic nerve transection.
Q34095403Neuroprotective effect of ischemic preconditioning in focal cerebral infarction: relationship with upregulation of vascular endothelial growth factor
Q35891863Neuroprotective effects of ischemic preconditioning in brain mitochondria following cerebral ischemia
Q46460370Neuroprotective effects of preconditioning ischaemia on ischaemic brain injury through inhibition of mixed-lineage kinase 3 via NMDA receptor-mediated Akt1 activation
Q46410692Neuroprotective effects of preconditioning ischemia on ischemic brain injury through down-regulating activation of JNK1/2 via N-methyl-D-aspartate receptor-mediated Akt1 activation
Q48359872Neuropsychological profile of persons with anoxic brain injury: differences regarding physiopathological mechanism
Q44826165Neurotrophism of bone marrow stromal cells to embryonic stem cells: noncontact induction and transplantation to a mouse ischemic stroke model
Q49062681Neurovascular protection by ischaemic tolerance: role of nitric oxide
Q33692425New insights into cardioprotection by ischemic preconditioning and other forms of stress
Q48469170Nitric oxide participates in the induction of brain ischemic tolerance via activating ERK1/2 signaling pathways
Q79963185Nitric oxide produced during ischemia is toxic but crucial to preconditioning-induced ischemic tolerance of neurons in culture
Q46941566Nitric oxide produced during sublethal ischemia is crucial for the preconditioning-induced down-regulation of glutamate transporter GLT-1 in neuron/astrocyte co-cultures
Q36079329Nitric oxide: considerations for the treatment of ischemic stroke
Q28082190Non-Coding RNAs in Stroke and Neuroprotection
Q34121828Non-invasive remote limb ischemic postconditioning protects rats against focal cerebral ischemia by upregulating STAT3 and reducing apoptosis.
Q48648228Normobaric hypoxia induces tolerance to focal permanent cerebral ischemia in association with an increased expression of hypoxia-inducible factor-1 and its target genes, erythropoietin and VEGF, in the adult mouse brain
Q39215230Notch signaling-mediated neural lineage selection facilitates intrastriatal transplantation therapy for ischemic stroke by promoting endogenous regeneration in the hippocampus
Q38527790Novel Cellular Mechanisms for Neuroprotection in Ischemic Preconditioning: A View from Inside Organelles.
Q38871467Novel Treatments in Neuroprotection for Aneurysmal Subarachnoid Hemorrhage
Q81351610Nucleotide hydrolysis in rats submitted to global cerebral ischemia: a possible link between preconditioning and adenosine production
Q33321139Overexpression of UCP2 protects thalamic neurons following global ischemia in the mouse
Q40809083Oxidative preconditioning and apoptosis in L-cells. Roles of protein kinase B and mitogen-activated protein kinases.
Q46557903Oxidative stress activates transcription factor NF-kB-mediated protective signaling in primary rat neuronal cultures
Q44347956Oxygen-sensitive {delta}-opioid receptor-regulated survival and death signals: novel insights into neuronal preconditioning and protection
Q57405393P1 and P2 receptors in cell growth and differentiation
Q73525689Permanent cerebral hypoperfusion: 'preconditioning-like' effects on rat energy metabolism towards acute systemic hypotension
Q42155325Persimmon leaf flavonoid induces brain ischemic tolerance in mice
Q41952540Persimmon leaf flavonoid promotes brain ischemic tolerance
Q72065176Pharmacologic brain protection: specific agents
Q44885318Pharmacological manipulations of ATP-dependent potassium channels and adenosine A1 receptors do not impact hippocampal ischemic preconditioning in vivo: evidence in a highly quantitative gerbil model
Q36771142Pharmacological neuroprotection during cardiac surgery
Q35878138Phosphorylated mitogen-activated protein kinase/extracellular signal-regulated kinase 1/2 may not always represent its kinase activity in a rat model of focal cerebral ischemia with or without ischemic preconditioning
Q38294544Phosphorylation of cAMP response element-binding protein in hippocampal neurons as a protective response after exposure to glutamate in vitro and ischemia in vivo.
Q28573943Phosphorylation-dependent subcellular localization of the small heat shock proteins HspB1/Hsp25 and HspB5/αB-crystallin in cultured hippocampal neurons
Q38344068Positive correlation between prolonged potentiation of binding of double-stranded oligonucleotide probe for the transcription factor AP1 and resistance to transient forebrain ischemia in gerbil hippocampus.
Q38334786Possible involvement of activator protein-1 DNA binding in mechanisms underlying ischemic tolerance in the CA1 subfield of gerbil hippocampus
Q37352186Post-ischemic brain damage: effect of ischemic preconditioning and postconditioning and identification of potential candidates for stroke therapy
Q48490706Postischemic hyperthermia increases expression of hsp72 mRNA after brief ischemia in the gerbil
Q40612077Postischemic temperature as a modulator of the stress response in brain: dissociation of heat shock protein 72 induction from ischemic tolerance after bilateral carotid artery occlusion in the gerbil
Q33632137Potential role of calcineurin for brain ischemia and traumatic injury
Q43516522Potentiation by histamine of synaptically mediated excitotoxicity in cultured hippocampal neurones: a possible role for mast cells
Q43061983Pre-conditioning protection in the brain
Q42935933Pre-ischemic treadmill training induces tolerance to brain ischemia: involvement of glutamate and ERK1/2.
Q44194863Preconditioned resistance to oxygen-glucose deprivation-induced cortical neuronal death: alterations in vesicular GABA and glutamate release
Q26830665Preconditioning for traumatic brain injury
Q48513175Preconditioning in vivo ischemia inhibits anoxic long-term potentiation and functionally protects CA1 neurons in the gerbil
Q35672764Preconditioning induces sustained neuroprotection by downregulation of adenosine 5'-monophosphate-activated protein kinase
Q37401700Preconditioning neuroprotection in global cerebral ischemia involves NMDA receptor-mediated ERK-JNK3 crosstalk
Q48858502Preconditioning of primary rat neuronal cultures against ischemic injury: characterization of the "time window of protection'.
Q37607849Preconditioning provides neuroprotection in models of CNS disease: paradigms and clinical significance.
Q86924137Preconditioning the human brain: practical considerations for proving cerebral protection
Q26853415Preconditioning the human brain: proving the principle in subarachnoid hemorrhage
Q38785169Preconditioning with recombinant high-mobility group box 1 induces ischemic tolerance in a rat model of focal cerebral ischemia-reperfusion
Q33694824Preconditioning-induced ischemic tolerance: a window into endogenous gearing for cerebroprotection
Q73822268Preconditioning-induced neuroprotection is mediated by reactive oxygen species
Q48821577Preferential conditions for and possible mechanisms of induction of ischemic tolerance by repeated hyperbaric oxygenation in gerbil hippocampus
Q48468079Propentofylline potentiates induced ischemic tolerance in gerbil hippocampal neurons via adenosine receptor
Q28363806Protection against beta-amyloid peptide toxicity in vivo with long-term administration of ferulic acid
Q34488047Protection of Tong-Sai-Mai Decoction against Apoptosis Induced by H2O2 in PC12 Cells: Mechanisms via Bcl-2-Mitochondria-ROS-INOS Pathway
Q40973614Protection of neuronal cells from apoptosis by Hsp27 delivered with a herpes simplex virus-based vector
Q49120809Protective conditioning of the brain: expressway or roadblock?
Q38921618Protective effect of hypoxic preconditioning on hypoxic-ischemic injured newborn rats
Q48449365Protective effect of tanreqing injection on axon myelin damage in the brain of mouse model for experimental autoimmune encephalomyelitis.
Q26825585Protective effects and mechanisms of sirtuins in the nervous system
Q48974568Protective preconditioning by transient global ischemia in the rat: components of delayed injury progression and lasting protection distinguished by comparisons of depolarization thresholds for cell loss at long survival times
Q28397786Protein Oxidative Modifications: Beneficial Roles in Disease and Health
Q37286391Protein kinase C regulation of neuronal zinc signaling mediates survival during preconditioning
Q48406263Rapamycin preconditioning attenuates transient focal cerebral ischemia/reperfusion injury in mice
Q34446404Rapid degradation of Bim by the ubiquitin-proteasome pathway mediates short-term ischemic tolerance in cultured neurons
Q41978908Rapid ischemic tolerance induced by adenosine preconditioning results in Bcl-2 interacting mediator of cell death (Bim) degradation by the proteasome.
Q43874157Rapid tolerance to focal cerebral ischemia in rats is attenuated by adenosine A1 receptor antagonist
Q42828608Reaction of small heat-shock proteins to different kinds of cellular stress in cultured rat hippocampal neurons
Q26771748Reconciling the IPC and Two-Hit Models: Dissecting the Underlying Cellular and Molecular Mechanisms of Two Seemingly Opposing Frameworks
Q48379507Recovery of protein synthesis in tolerance-induced hippocampal CA1 neurons after transient forebrain ischemia
Q35193898Redox regulation of intracellular zinc: molecular signaling in the life and death of neurons
Q73583760Reduced [3H]IP3 binding but unchanged IP3 receptor levels in the rat hippocampus CA1 region following transient global ischemia and tolerance induction
Q73455064Reduced glutathione oxidation ratio and 8 ohdG accumulation by mild ischemic pretreatment
Q73731779Reduced nitric oxide is involved in prenatal ischemia-induced tolerance to neonatal hypoxic-ischemic brain injury in rats
Q90440292Refocusing the Brain: New Approaches in Neuroprotection Against Ischemic Injury
Q90408077Regulation of gene expression in ischemic preconditioning in the brain
Q41068412Regulatory mechanism of stress response in mammalian nervous system during cerebral ischaemia or after heat shock
Q34680534Remifentanil ameliorates intestinal ischemia-reperfusion injury
Q38639332Remote ischaemic conditioning-a new paradigm of self-protection in the brain.
Q34171579Remote ischemic limb preconditioning after subarachnoid hemorrhage: a phase Ib study of safety and feasibility
Q44239801Repeated cerebral ischemia induced hippocampal cell death and impairments of spatial cognition in the rat.
Q48443046Repeated electroacupuncture preconditioning attenuates matrix metalloproteinase-9 expression and activity after focal cerebral ischemia in rats
Q37368451Repeated exposure to MDMA provides neuroprotection against subsequent MDMA-induced serotonin depletion in brain
Q48859766Repeated hyperbaric oxygen induces ischemic tolerance in gerbil hippocampus
Q73985050Repetitive intermittent hypoxia-ischemia and brain damage in neonatal rats
Q48509770Repetitive transient forebrain ischemia in gerbils: delayed neuronal damage in the substantia nigra reticulata
Q37156312Requirement for nitric oxide activation of p21(ras)/extracellular regulated kinase in neuronal ischemic preconditioning
Q51569121Response variability to ischemic injury in the Mongolian gerbil: an electroencephalographic and behavioral study.
Q38824286Review of remote ischemic preconditioning: from laboratory studies to clinical trials
Q27003832Role of MicroRNAs in innate neuroprotection mechanisms due to preconditioning of the brain
Q50225669Role of P2X7 purinoceptors in neuroprotective mechanism of ischemic postconditioning in mice
Q36015593Role of histamine and its receptors in cerebral ischemia
Q42114880Role of mitochondrial ATP-sensitive potassium channel-mediated PKC-ε in delayed protection against myocardial ischemia/reperfusion injury in isolated hearts of sevoflurane-preconditioned rats
Q30482431Role of prostaglandin E receptor subtypes EP2 and EP4 in autocrine and paracrine functions of vascular endothelial growth factor in the inner ear.
Q38544023Role of the Toll‑like receptor 3 signaling pathway in the neuroprotective effect of sevoflurane pre‑conditioning during cardiopulmonary bypass in rats
Q34067828Roles of molecular chaperones in the nervous system
Q37056590Secondary stroke prevention: inside the vessels and beyond
Q34617266Seizure preconditioning and epileptic tolerance: models and mechanisms
Q72048513Selective c‐JUN Expression in CA1 Neurons of the Gerbil Hippocampus during and after Acquisition of an Ischemia‐Tolerant State
Q64228796Short-term remote ischemic conditioning may protect monkeys after ischemic stroke
Q42521563Sleep impairment by diethyldithiocarbamate in rat. Protective effects of pre-conditioning and antioxidants
Q40825906Stress protein and proto-oncogene expression as indicators of neuronal pathophysiology after ischemia.
Q35031242Stress proteins and glial functions: possible therapeutic targets for neurodegenerative disorders
Q48969161Stress proteins and tolerance to focal cerebral ischemia
Q34298120Stroke genomics: approaches to identify, validate, and understand ischemic stroke gene expression
Q60597094Subcellular distribution and autophosphorylation of calcium/calmodulin-dependent protein kinase II-α in rat hippocampus in a model of ischemic tolerance
Q48567847Sublethal oxygen-glucose deprivation alters hippocampal neuronal AMPA receptor expression and vulnerability to kainate-induced death
Q37415135Sumo-2/3-ylation following in vitro modeled ischemia is reduced in delayed ischemic tolerance
Q48111602Superoxide dismutase, catalase, and U78517F attenuate neuronal damage in gerbils with repeated brief ischemic insults
Q48762052Suppression subtraction hybridization and northern analysis reveal upregulation of heat shock, trkB, and sodium calcium exchanger genes following global cerebral ischemia in the rat.
Q40917132Synthesis of heat shock/stress proteins during cellular injury
Q48714135TNF-alpha pretreatment induces protective effects against focal cerebral ischemia in mice
Q38332109TNFR1 upregulation mediates tolerance after brain ischemic preconditioning.
Q50850834Tadalafil enhances the neuroprotective effects of ischemic postconditioning in mice, probably in a nitric oxide associated manner.
Q40328996Targets of cytoprotection in acute ischemic stroke: present and future.
Q28344385The A3 adenosine receptor induces cytoskeleton rearrangement in human astrocytoma cells via a specific action on Rho proteins
Q55078229The Janus Face of VEGF in Stroke.
Q38874786The Protective Effects of Ischemic Postconditioning against Stroke: From Rapid to Delayed and Remote Postconditioning
Q40619450The Protective Effects of Preconditioning on Cerebral Endothelial Cells in Vitro
Q35078174The adaptive effects of hypoxic preconditioning of brain neurons
Q34047324The adenosine-induced mechanism for the acquisition of ischemic tolerance in primary rat neuronal cultures
Q36308199The age-associated loss of ischemic preconditioning in the kidney is accompanied by mitochondrial dysfunction, increased protein acetylation and decreased autophagy
Q34061901The effect of treadmill training pre-exercise on glutamate receptor expression in rats after cerebral ischemia
Q33907949The effects of CoCl2 on HIF-1α protein under experimental conditions of autoprogressive hypoxia using mouse models
Q93934928The effects of thrombin preconditioning on focal cerebral ischemia in rats
Q81114873The expression pattern of pro- and antiapoptotic proteins bax and Bcl-2 in rat brain neurons in response to severe hypobaric hypoxia: the correcting effect of hypoxic preconditioning
Q41491290The heat shock stress response after brain lesions: induction of 72 kDa heat shock protein (cell types involved, axonal transport, transcriptional regulation) and protein synthesis inhibition
Q45997124The infarct-limiting effect of cerebral ischaemic postconditioning in rats depends on the middle cerebral artery branching pattern.
Q48391396The mitochondrial antioxidants thioredoxin-2 and Mn-superoxide dismutase are involved in the mechanisms of brain hypoxic tolerance
Q48265009The neuroprotective effect of propofol against brain ischemia mediated by the glutamatergic signaling pathway in rats
Q46845541The phenomenon of "pre-ischaemic conditioning" in the brain only partly involves the NMDA receptor: a magnetic resonance study
Q74534794The regional changes of the catalytic NOS activity in the spinal cord of the rabbit after repeated sublethal ischemia
Q48241154The reversible change of GluR2 RNA editing in gerbil hippocampus in course of ischemic tolerance
Q47749826The role of glutamate transporter-1 in the acquisition of brain ischaemic tolerance in rats induced by electro-acupuncture pre-treatment
Q48860529The role of glutamate transporter-1a in the induction of brain ischemic tolerance in rats
Q92447559The role of microglia in ischemic preconditioning
Q48145538The role of nitric oxide in the neuroprotection of limb ischemic preconditioning in rats
Q41835129The role of protein kinase C in ischemic tolerance induced by hyperoxia in rats with stroke
Q37381217The role of the ubiquitin proteasome system in ischemia and ischemic tolerance
Q34021791The role of volume transmission of adaptogenic signals in forming the adaptive reactions of the brain
Q48307835The upregulation of glial glutamate transporter-1 participates in the induction of brain ischemic tolerance in rats
Q51944494Thioredoxin-1 expression levels in rat hippocampal neurons in moderate hypobaric hypoxia.
Q48597343Time course of neuroprotection induced by normobaric hyperoxia in focal cerebral ischemia
Q55413803Total Flavones of Rhododendron simsii Planch Flower Protect against Cerebral Ischemia-Reperfusion Injury via the Mechanism of Cystathionine-γ-Lyase-Produced H2S.
Q28194708Trans-synaptic increase of hypoxic tolerance in hippocampus upon physical challenge with two-photon microscopy
Q72615825Transfection-mediated expression of human Hsp70i protects rat dorsal root ganglian neurones and glia from severe heat stress
Q44606742Transforming growth factor-beta 1-mediated neuroprotection against excitotoxic injury in vivo
Q73011059Transient NMDA receptor inactivation provides long-term protection to cultured cortical neurons from a variety of death signals
Q48887030Translational downregulation of the noncatalytic growth factor receptor TrkB.T1 by ischemic preconditioning of primary neurons.
Q39274473Ubiquitin proteasome-mediated synaptic reorganization: a novel mechanism underlying rapid ischemic tolerance
Q48158722Ubiquitin stress response in postischemic hippocampal neurons under nontolerant and tolerant conditions
Q48354229Use of suppression subtractive hybridization strategy for discovery of increased tissue inhibitor of matrix metalloproteinase-1 gene expression in brain ischemic tolerance
Q38113219Using hormetic strategies to improve ischemic preconditioning and postconditioning against stroke
Q27028225Vitreous mediators in retinal hypoxic diseases
Q33610147Zn2+ regulates Kv2.1 voltage-dependent gating and localization following ischemia
Q48922414bcl-2 Antisense treatment prevents induction of tolerance to focal ischemia in the rat brain
Q43247175epsilonPKC phosphorylates the mitochondrial K(+) (ATP) channel during induction of ischemic preconditioning in the rat hippocampus
Q49048566p38 MAPK Participates in the Mediation of GLT-1 Up-regulation During the Induction of Brain Ischemic Tolerance by Cerebral Ischemic Preconditioning
Q44805794‘Ischemic tolerance’ phenomenon detected in various brain regions

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