New and emerging therapies for acute and chronic graft versus host disease

scientific article published on 28 November 2017

New and emerging therapies for acute and chronic graft versus host disease is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1177/2040620717741860
P932PMC publication ID5753923
P698PubMed publication ID29317998

P50authorElizabeth J ShpallQ87373605
P2093author name stringKatayoun Rezvani
Partow Kebriaei
Amin Alousi
LaQuisa Hill
Rohtesh Mehta
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L-selectin and beta7 integrin on donor CD4 T cells are required for the early migration to host mesenteric lymph nodes and acute colitis of graft-versus-host diseaseQ42234577
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LPAM (α4β7 integrin) is an important homing integrin on alloreactive T cells in the development of intestinal graft-versus-host diseaseQ44620762
Successful treatment of severe acute intestinal graft-versus-host resistant to systemic and topical steroids with alemtuzumabQ44761574
Recipient nonhematopoietic antigen-presenting cells are sufficient to induce lethal acute graft-versus-host diseaseQ44925138
Different efficacy of mycophenolate mofetil as salvage treatment for acute and chronic GVHD after allogeneic stem cell transplantQ44925296
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Response of Steroid-Refractory Acute GVHD to α1-AntitrypsinQ46361757
Ibrutinib for chronic graft-versus-host disease after failure of prior therapyQ46428638
Extracorporeal photopheresis for the treatment of steroid refractory acute GVHD.Q46460065
The proteasome inhibitor bortezomib depletes plasma cells and protects mice with lupus-like disease from nephritisQ46549173
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High donor FOXP3-positive regulatory T-cell (Treg) content is associated with a low risk of GVHD following HLA-matched allogeneic SCTQ35849935
Tolerance, not immunity, crucially depends on IL-2.Q35877199
Intestinal Blautia Is Associated with Reduced Death from Graft-versus-Host DiseaseQ35892249
Advances in understanding the pathogenesis of graft-versus-host diseaseQ35971439
Mesenchymal stem cell therapy in the treatment of acute and chronic graft versus host diseaseQ35971980
First- and second-line systemic treatment of acute graft-versus-host disease: recommendations of the American Society of Blood and Marrow TransplantationQ36113205
Pathogenesis of acute graft-versus-host disease: from intestinal microbiota alterations to donor T cell activationQ36130498
B cells from patients with chronic GVHD are activated and primed for survival via BAFF-mediated pathwaysQ36250962
Adhesion molecules in inflammatory bowel disease: therapeutic implications for gut inflammation.Q36259898
A case for regulatory B cellsQ36360842
IFNγR signaling mediates alloreactive T-cell trafficking and GVHDQ36395621
Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regenerationQ36483525
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Regulatory T cells and transplantation toleranceQ36630515
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Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism.Q36851405
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An essential role for the IL-2 receptor in Treg cell functionQ37351745
Fecal microbiota transplantation for patients with steroid-resistant acute graft-versus-host disease of the gut.Q37376599
Therapy with mycophenolate mofetil for refractory acute and chronic GVHD.Q37468247
New perspectives on the biology of acute GVHD.Q37641063
Sirolimus in combination with tacrolimus and corticosteroids for the treatment of resistant chronic graft-versus-host diseaseQ46617730
An orally bioavailable spleen tyrosine kinase inhibitor delays disease progression and prolongs survival in murine lupusQ46625173
Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches.Q47365613
Tumor necrosis factor-alpha blockade for the treatment of acute GVHD.Q47804385
Blockade of Syk ameliorates the development of murine sclerodermatous chronic graft-versus-host disease.Q50855347
Spleen tyrosine kinase (Syk) is a potent target for GvHD prevention at different cellular levels.Q52621229
Targeting Integrin α4β7 in Steroid-Refractory Intestinal Graft-versus-Host Disease.Q52994863
Extracorporeal photochemotherapy for treatment of acute and chronic GVHD in childhood.Q53990752
Extracorporeal photochemotherapy in the treatment of severe steroid-refractory acute graft-versus-host disease: a pilot study.Q54035816
Specificity of JAK-kinase inhibition determines impact on human and murine T-cell function.Q54254821
Spleen tyrosine kinase is important in the production of proinflammatory cytokines and cell proliferation in human mesangial cells following stimulation with IgA1 isolated from IgA nephropathy patients.Q54485643
Chronic graft-versus-host diseaseQ56340012
CD4+CD25high regulatory cells in human peripheral bloodQ56905059
Donor interleukin-22 and host type I interferon signaling pathway participate in intestinal graft-versus-host disease via STAT1 activation and CXCL10Q57194209
IL-22 deficiency in donor T cells attenuates murine acute graft-versus-host disease mortality while sparing the graft-versus-leukemia effectQ57194234
B-cell involvement in chronic graft-versus-host diseaseQ57676591
Infliximab treatment for steroid-refractory acute graft-versus-host diseaseQ59281270
Platelet-lysate-Expanded Mesenchymal Stromal Cells as a Salvage Therapy for Severe Resistant Graft-versus-Host Disease in a Pediatric PopulationQ59713756
Mesenchymal Stem Cells for Treatment of Therapy-Resistant Graft-versus-Host DiseaseQ63197317
Blocking L-selectin and alpha4-integrin changes donor cell homing pattern and ameliorates murine acute graft versus host diseaseQ73444018
Circulating levels of soluble CD30 are increased in patients with localized scleroderma and correlated with serological and clinical features of the diseaseQ73613538
CD30+ T cells in rheumatoid synovitis: mechanisms of recruitment and functional roleQ73644574
Inhibition of NF-kappaB-dependent T cell activation abrogates acute allograft rejectionQ77137086
Recombinant human tumor necrosis factor receptor fusion protein as complementary treatment for chronic graft-versus-host diseaseQ77754791
Recombinant human soluble tumor necrosis factor receptor fusion protein as treatment for steroid refractory graft-versus-host disease following allogeneic hematopoietic stem cell transplantationQ80177840
Inhibition of chronic graft-vs-host disease with retention of anti-myeloma effects by the proteasome inhibitor bortezomibQ80288306
Donor APCs are required for maximal GVHD but not for GVLQ80402910
Use of bortezomib in the management of chronic graft-versus-host disease among multiple myeloma patients relapsing after allogeneic transplantationQ80984434
Application of multipotent mesenchymal stromal cells in pediatric patients following allogeneic stem cell transplantationQ81298136
Phase II study of pentostatin in patients with corticosteroid-refractory chronic graft-versus-host diseaseQ81317575
Treatment of refractory acute GVHD with third-party MSC expanded in platelet lysate-containing mediumQ82092596
Chronic graft-versus-host diseaseQ82325119
IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasisQ83163682
Therapy of steroid-refractory acute GVHD with CD52 antibody alemtuzumab is effectiveQ83940125
First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4+CD25+CD127- T regulatory cellsQ84135263
Efficacy of bone marrow-derived mesenchymal stem cells in the treatment of sclerodermatous chronic graft-versus-host disease: clinical reportQ84931084
Adoptive transfer of allogeneic regulatory T cells into patients with chronic graft-versus-host diseaseQ86499606
Activity of therapeutic JAK 1/2 blockade in graft-versus-host diseaseQ87635679
P433issue1
P921main subjectChronic graft versus host diseaseQ111329725
P304page(s)21-46
P577publication date2017-11-28
P1433published inTherapeutic advances in hematologyQ26842172
P1476titleNew and emerging therapies for acute and chronic graft versus host disease
P478volume9

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