| scholarly article | Q13442814 |
| review article | Q7318358 |
| P50 | author | Elke Heiss | Q73104826 |
| Manuel Matzinger | Q91586261 | ||
| P2093 | author name string | Katrin Fischhuber | |
| P2860 | cites work | Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1 | Q22011167 |
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| Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray | Q28202142 | ||
| Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis | Q28242612 | ||
| Differential responses of the Nrf2-Keap1 system to laminar and oscillatory shear stresses in endothelial cells | Q28252919 | ||
| The anti-inflammatory sesquiterpene lactone helenalin inhibits the transcription factor NF-kappaB by directly targeting p65 | Q28290401 | ||
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| Curcumin inhibits hepatic protein-tyrosine phosphatase 1B and prevents hypertriglyceridemia and hepatic steatosis in fructose-fed rats | Q34103434 | ||
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| Curcumin improves insulin resistance in skeletal muscle of rats | Q34103820 | ||
| Sensory neurons and schwann cells respond to oxidative stress by increasing antioxidant defense mechanisms | Q34104944 | ||
| Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis | Q34146310 | ||
| MiR-28 regulates Nrf2 expression through a Keap1-independent mechanism | Q34189586 | ||
| Bardoxolone methyl and kidney function in CKD with type 2 diabetes | Q34194954 | ||
| Advanced glycation end-products: a review | Q34196489 | ||
| Dietary regulation of Keap1/Nrf2/ARE pathway: focus on plant-derived compounds and trace minerals | Q34263561 | ||
| Nrf2-MafG heterodimers contribute globally to antioxidant and metabolic networks | Q34298880 | ||
| Protein kinase C activation: isozyme-specific effects on metabolism and cardiovascular complications in diabetes | Q34300442 | ||
| Detecting causality in complex ecosystems | Q34300961 | ||
| Regulation of Nrf2 transactivation domain activity. The differential effects of mitogen-activated protein kinase cascades and synergistic stimulatory effect of Raf and CREB-binding protein | Q34305832 | ||
| microRNA miR-144 modulates oxidative stress tolerance and associates with anemia severity in sickle cell disease | Q34360379 | ||
| Bardoxolone methyl in type 2 diabetes and stage 4 chronic kidney disease | Q34383685 | ||
| The Triterpenoid 2-Cyano-3,12-dioxooleana-1,9-dien-28-oic-acid Methyl Ester Has Potent Anti-diabetic Effects in Diet-induced Diabetic Mice and Lepr Mice | Q34412580 | ||
| Heme oxygenase-1 drives metaflammation and insulin resistance in mouse and man. | Q34427919 | ||
| Chemistry: Chemical con artists foil drug discovery | Q34440392 | ||
| Genetic polymorphism in the NRF2 gene as a prognosis marker for cancer chemotherapy | Q34448767 | ||
| Epigenetic modifications of Keap1 regulate its interaction with the protective factor Nrf2 in the development of diabetic retinopathy | Q34511162 | ||
| Meriva®, a lecithinized curcumin delivery system, in diabetic microangiopathy and retinopathy | Q34513505 | ||
| The anti-inflammatory natural product parthenolide from the medicinal herb Feverfew directly binds to and inhibits IkappaB kinase | Q34517140 | ||
| Cell signaling. H2O2, a necessary evil for cell signaling | Q34543124 | ||
| Diabetic Retinopathy: A Position Statement by the American Diabetes Association. | Q34551730 | ||
| Oral supplementation of turmeric attenuates proteinuria, transforming growth factor-β and interleukin-8 levels in patients with overt type 2 diabetic nephropathy: a randomized, double-blind and placebo-controlled study. | Q34629660 | ||
| Dimethyl fumarate in the treatment of relapsing-remitting multiple sclerosis: an overview | Q34667496 | ||
| Effect of coenzyme Q10 alone and its combination with metformin on streptozotocin-nicotinamide-induced diabetic nephropathy in rats | Q34684640 | ||
| Nrf2 and redox status in prediabetic and diabetic patients | Q34685338 | ||
| Metabolic effects of metformin in non-insulin-dependent diabetes mellitus | Q34720764 | ||
| Loss of Nrf2 in mice evokes a congenital intrahepatic shunt that alters hepatic oxygen and protein expression gradients and toxicity | Q34737012 | ||
| Adaptive induction of NF-E2-related factor-2-driven antioxidant genes in endothelial cells in response to hyperglycemia | Q34784446 | ||
| Fibroblast growth factor 21 corrects obesity in mice | Q34805555 | ||
| Modification of keap1 cysteine residues by sulforaphane | Q34909588 | ||
| Modulation of Nrf2-mediated antioxidant and detoxifying enzyme induction by the green tea polyphenol EGCG. | Q37033323 | ||
| The Keap1-Nrf2 system prevents onset of diabetes mellitus | Q37036376 | ||
| Metallothionein MT2A A-5G Polymorphism as a Risk Factor for Chronic Kidney Disease and Diabetes: Cross-Sectional and Cohort Studies | Q37041899 | ||
| Antioxidants Enhance Mammalian Proteasome Expression through the Keap1-Nrf2 Signaling Pathway | Q37062266 | ||
| Islet inflammation in type 2 diabetes: from metabolic stress to therapy. | Q37069944 | ||
| AMPK Facilitates Nuclear Accumulation of Nrf2 by Phosphorylating at Serine 550 | Q37073162 | ||
| Human islets contain four distinct subtypes of β cells | Q37089019 | ||
| Mitochondrial reactive oxygen species are obligatory signals for glucose-induced insulin secretion. | Q37105339 | ||
| Broccoli sprout extract prevents diabetic cardiomyopathy via Nrf2 activation in db/db T2DM mice | Q37125260 | ||
| Protective effects of curcumin on retinal Müller cell in early diabetic rats | Q37126821 | ||
| Molecular mechanisms of natural products in chemoprevention: induction of cytoprotective enzymes by Nrf2. | Q37147156 | ||
| Association Between Heme Oxygenase-1 Promoter Polymorphisms and the Development of Albuminuria in Type 2 Diabetes: A Case-Control Study | Q37176238 | ||
| Translational control of Nrf2 within the open reading frame | Q37190534 | ||
| Retinal ganglion cells in diabetes | Q37195552 | ||
| The pathogenesis of diabetic nephropathy | Q37209550 | ||
| Cellular stress response: a novel target for chemoprevention and nutritional neuroprotection in aging, neurodegenerative disorders and longevity. | Q37217435 | ||
| Renoprotective effect of the antioxidant curcumin: Recent findings. | Q37272692 | ||
| Heat-processed Panax ginseng and diabetic renal damage: active components and action mechanism | Q37303174 | ||
| Diabetes and Kidney Disease: Role of Oxidative Stress | Q37349206 | ||
| Genetic variants of nuclear factor erythroid-derived 2-like 2 associated with the complications in Han descents with type 2 diabetes mellitus of Northeast China | Q37370799 | ||
| Diabetic neuropathy: mechanisms, emerging treatments, and subtypes | Q37375109 | ||
| Neural apoptosis in the retina during experimental and human diabetes. Early onset and effect of insulin | Q37384532 | ||
| beta-Cell-specific overexpression of glutathione peroxidase preserves intranuclear MafA and reverses diabetes in db/db mice | Q37418222 | ||
| Fasting induces nuclear factor E2-related factor 2 and ATP-binding Cassette transporters via protein kinase A and Sirtuin-1 in mouse and human | Q37433915 | ||
| Dopamine deficiency contributes to early visual dysfunction in a rodent model of type 1 diabetes | Q37479451 | ||
| The crosstalk between Nrf2 and AMPK signal pathways is important for the anti-inflammatory effect of berberine in LPS-stimulated macrophages and endotoxin-shocked mice | Q37513209 | ||
| The mitochondria-targeted antioxidant MitoQ ameliorated tubular injury mediated by mitophagy in diabetic kidney disease via Nrf2/PINK1. | Q37541642 | ||
| Notch-Nrf2 axis: regulation of Nrf2 gene expression and cytoprotection by notch signaling. | Q37546854 | ||
| Stress and the inflammatory process: a major cause of pancreatic cell death in type 2 diabetes. | Q37568237 | ||
| NOX Activation by Subunit Interaction and Underlying Mechanisms in Disease | Q37574976 | ||
| Happily (n)ever after: Aging in the context of oxidative stress, proteostasis loss and cellular senescence | Q37581663 | ||
| A protective role of nuclear factor-erythroid 2-related factor-2 (Nrf2) in inflammatory disorders | Q37607440 | ||
| Association of Genomic Instability with HbA1c levels and Medication in Diabetic Patients. | Q37620728 | ||
| Sulforaphane attenuation of type 2 diabetes-induced aortic damage was associated with the upregulation of Nrf2 expression and function | Q37636031 | ||
| Epalrestat Upregulates Heme Oxygenase-1, Superoxide Dismutase, and Catalase in Cells of the Nervous System | Q38756779 | ||
| Current Therapies for the Medical Management of Diabetes | Q38766876 | ||
| TAK1 Regulates the Nrf2 Antioxidant System Through Modulating p62/SQSTM1. | Q38767311 | ||
| Dimethyl fumarate ameliorates dextran sulfate sodium-induced murine experimental colitis by activating Nrf2 and suppressing NLRP3 inflammasome activation | Q38770586 | ||
| Bioactive compounds isolated from apple, tea, and ginger protect against dicarbonyl induced stress in cultured human retinal epithelial cells | Q38790188 | ||
| Metformin and Prostate Cancer: a New Role for an Old Drug. | Q38819039 | ||
| Heme Oxygenases in Cardiovascular Health and Disease | Q38823562 | ||
| The changing face of diabetes complications | Q38828410 | ||
| Controversy about pharmacological modulation of Nrf2 for cancer therapy | Q38835943 | ||
| The Keap1-Nrf2-ARE Pathway As a Potential Preventive and Therapeutic Target: An Update | Q38837451 | ||
| The islet endothelial cell: a novel contributor to beta cell secretory dysfunction in diabetes | Q38843326 | ||
| Nrf2 activators modulate oxidative stress responses and bioenergetic profiles of human retinal epithelial cells cultured in normal or high glucose conditions | Q38851637 | ||
| Targeting ABL-IRE1α signaling spares ER-stressed pancreatic β cells to reverse autoimmune diabetes | Q38852387 | ||
| Metabolic control of the proteotoxic stress response: implications in diabetes mellitus and neurodegenerative disorders | Q38862319 | ||
| Emerging role of NRF2 in chemoresistance by regulating drug-metabolizing enzymes and efflux transporters. | Q38869922 | ||
| Using systems biology to evaluate targets and mechanism of action of drugs for diabetes comorbidities | Q38885386 | ||
| Cytoprotective pathways in the vascular endothelium. Do they represent a viable therapeutic target? | Q38926413 | ||
| Multiple regulations of Keap1/Nrf2 system by dietary phytochemicals | Q38927510 | ||
| Pterostilbene Ameliorates Streptozotocin-Induced Diabetes through Enhancing Antioxidant Signaling Pathways Mediated by Nrf2. | Q38928429 | ||
| Opposing effects of Nrf2 and Nrf2-activating compounds on the NLRP3 inflammasome independent of Nrf2-mediated gene expression | Q38936140 | ||
| An overview of chemical inhibitors of the Nrf2-ARE signaling pathway and their potential applications in cancer therapy | Q38955805 | ||
| Rexinoid inhibits Nrf2-mediated transcription through retinoid X receptor alpha. | Q38961531 | ||
| Key elements of metabolomics in the study of biomarkers of diabetes | Q38974645 | ||
| Epigenetic modifications of Nrf2-mediated glutamate-cysteine ligase: implications for the development of diabetic retinopathy and the metabolic memory phenomenon associated with its continued progression | Q38976111 | ||
| The bromodomain protein BRD4 regulates the KEAP1/NRF2-dependent oxidative stress response. | Q38993234 | ||
| Nrf2 signaling pathway: Pivotal roles in inflammation. | Q39003225 | ||
| Actinidia callosa peel (kiwi fruit) ethanol extracts protected neural cells apoptosis induced by methylglyoxal through Nrf2 activation | Q39007027 | ||
| Mediators of diabetic neuropathy: is hyperglycemia the only culprit? | Q39015184 | ||
| Molecular mechanisms of ROS production and oxidative stress in diabetes. | Q39035668 | ||
| Role of endoplasmic reticulum stress signalling in diabetic endothelial dysfunction and atherosclerosis | Q39035700 | ||
| Epalrestat increases intracellular glutathione levels in Schwann cells through transcription regulation | Q39040897 | ||
| Epigenetic regulation of redox signaling in diabetic retinopathy: Role of Nrf2. | Q39052777 | ||
| Naturally Occurring Nrf2 Activators: Potential in Treatment of Liver Injury. | Q39094306 | ||
| Diabetes and arterial extracellular matrix changes in a porcine model of atherosclerosis | Q37643127 | ||
| Therapeutic potential of pterostilbene against pancreatic beta-cell apoptosis mediated through Nrf2. | Q37665625 | ||
| Xanthohumol ameliorates lipopolysaccharide (LPS)-induced acute lung injury via induction of AMPK/GSK3β-Nrf2 signal axis | Q37693737 | ||
| miRNA-141 attenuates UV-induced oxidative stress via activating Keap1-Nrf2 signaling in human retinal pigment epithelium cells and retinal ganglion cells | Q37706575 | ||
| Impact of high cholesterol and endoplasmic reticulum stress on metabolic diseases: An updated mini-review | Q37710429 | ||
| Cytoprotective effect of chlorogenic acid against hydrogen peroxide-induced oxidative stress in MC3T3-E1 cells through PI3K/Akt-mediated Nrf2/HO-1 signaling pathway | Q37716417 | ||
| Evidence for Loss in Identity, De-Differentiation, and Trans-Differentiation of Islet β-Cells in Type 2 Diabetes | Q37729482 | ||
| Sirtuin 2 regulates cellular iron homeostasis via deacetylation of transcription factor NRF2. | Q37730645 | ||
| Impaired redox signaling and antioxidant gene expression in endothelial cells in diabetes: a role for mitochondria and the nuclear factor-E2-related factor 2-Kelch-like ECH-associated protein 1 defense pathway | Q37762813 | ||
| The Nrf2 system as a potential target for the development of indirect antioxidants. | Q37802176 | ||
| Transforming growth factor-beta 1 induces extracellular matrix formation in glomerulonephritis | Q37803699 | ||
| Lipid peroxidation of membrane phospholipids in the vertebrate retina | Q37825284 | ||
| Bioavailability of resveratrol | Q37831925 | ||
| The cytoprotective role of the Keap1-Nrf2 pathway | Q37848718 | ||
| Oxidative stress and Nrf2 in the pathophysiology of diabetic neuropathy: old perspective with a new angle | Q37858072 | ||
| Cardiovascular morbidity and mortality in diabetes mellitus: prediction and prognosis. | Q37914329 | ||
| Does insulin bolster antioxidant defenses via the extracellular signal-regulated kinases-protein kinase B-nuclear factor erythroid 2 p45-related factor 2 pathway? | Q37965587 | ||
| Diabetes mellitus and the β cell: the last ten years | Q37994282 | ||
| Role of oxidative stress in diabetes-mediated vascular dysfunction: unifying hypothesis of diabetes revisited | Q38000380 | ||
| Crosstalk between Nrf2 and the proteasome: therapeutic potential of Nrf2 inducers in vascular disease and aging | Q38009084 | ||
| Chemoprotection against cancer by isothiocyanates: a focus on the animal models and the protective mechanisms | Q38023258 | ||
| Metabolic syndrome, insulin resistance, and roles of inflammation--mechanisms and therapeutic targets | Q38027826 | ||
| When less is more: the forbidden fruits of gene repression in the adult β-cell | Q38057374 | ||
| Signalling danger: endoplasmic reticulum stress and the unfolded protein response in pancreatic islet inflammation | Q38058245 | ||
| Hyperglycemia-induced oxidative stress and its role in diabetes mellitus related cardiovascular diseases | Q38085394 | ||
| Nuclear factor (erythroid-derived 2)-like-2 factor (Nrf2), a key regulator of the antioxidant response to protect against atherosclerosis and nonalcoholic steatohepatitis | Q38087926 | ||
| Nuclear factor (erythroid-derived 2)-like 2 (NFE2L2) is a novel therapeutic target for diabetic complications | Q38097416 | ||
| Nutritional strategies to modulate inflammation and oxidative stress pathways via activation of the master antioxidant switch Nrf2. | Q38104172 | ||
| Molecular understanding of curcumin in diabetic nephropathy | Q38104867 | ||
| Toward clinical application of the Keap1-Nrf2 pathway | Q38105775 | ||
| Nox as a target for diabetic complications | Q38114488 | ||
| Pathogenesis of diabetic neuropathy: focus on neurovascular mechanisms. | Q38122978 | ||
| The multifunctional role and therapeutic potential of HO-1 in the vascular endothelium | Q38153075 | ||
| ER stress in diabetic peripheral neuropathy: A new therapeutic target. | Q38175058 | ||
| Recent developments in delivery, bioavailability, absorption and metabolism of curcumin: the golden pigment from golden spice | Q38187406 | ||
| Reactive oxygen species mediate high glucose-induced plasminogen activator inhibitor-1 up-regulation in mesangial cells and in diabetic kidney | Q42477089 | ||
| Induction of heme oxygenase 1 by moderately oxidized low-density lipoproteins in human vascular smooth muscle cells: role of mitogen-activated protein kinases and Nrf2. | Q42480067 | ||
| Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation | Q42499319 | ||
| Pharmacological stimulation of nuclear factor (erythroid-derived 2)-like 2 translation activates antioxidant responses. | Q42512019 | ||
| Curcumin enhances recovery of pancreatic islets from cellular stress induced inflammation and apoptosis in diabetic rats | Q42703080 | ||
| Resveratrol upregulates Nrf2 expression to attenuate methylglyoxal-induced insulin resistance in Hep G2 cells | Q42716268 | ||
| Cinnamaldehyde enhances Nrf2 nuclear translocation to upregulate phase II detoxifying enzyme expression in HepG2 cells | Q42743920 | ||
| Resveratrol protects diabetic kidney by attenuating hyperglycemia-mediated oxidative stress and renal inflammatory cytokines via Nrf2-Keap1 signaling | Q42744612 | ||
| Pterostilbene is more potent than resveratrol in preventing azoxymethane (AOM)-induced colon tumorigenesis via activation of the NF-E2-related factor 2 (Nrf2)-mediated antioxidant signaling pathway | Q42748324 | ||
| Lithospermic acid B protects β-cells from cytokine-induced apoptosis by alleviating apoptotic pathways and activating anti-apoptotic pathways of Nrf2-HO-1 and Sirt1. | Q42752459 | ||
| Singularity analysis of the AKT signaling pathway reveals connections between cancer and metabolic diseases | Q42773929 | ||
| Characterization of Nrf2 activation and heme oxygenase-1 expression in NIH3T3 cells exposed to aqueous extracts of cigarette smoke | Q42808285 | ||
| Synergistic effects of metformin, resveratrol, and hydroxymethylbutyrate on insulin sensitivity | Q42825276 | ||
| H2O2-dependent activation of GCLC-ARE4 reporter occurs by mitogen-activated protein kinase pathways without oxidation of cellular glutathione or thioredoxin-1. | Q42833714 | ||
| Epalrestat increases glutathione, thioredoxin, and heme oxygenase-1 by stimulating Nrf2 pathway in endothelial cells | Q43047088 | ||
| Protective effects of magnesium lithospermate B against diabetic atherosclerosis via Nrf2-ARE-NQO1 transcriptional pathway. | Q43155390 | ||
| Luteolin improves the impaired nerve functions in diabetic neuropathy: behavioral and biochemical evidences | Q43183929 | ||
| Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice | Q43224118 | ||
| Activation of Nrf2 in endothelial cells protects arteries from exhibiting a proinflammatory state. | Q43281152 | ||
| Curcumin ameliorates diabetic nephropathy by inhibiting the activation of the SphK1-S1P signaling pathway | Q43443950 | ||
| Effect of NFE2L2 genetic polymorphism on the association between oral estrogen therapy and the risk of venous thromboembolism in postmenopausal women | Q43494908 | ||
| Pharmacodynamic and pharmacokinetic study of oral Curcuma extract in patients with colorectal cancer. | Q43670860 | ||
| Dietary flavonoid genistein induces Nrf2 and phase II detoxification gene expression via ERKs and PKC pathways and protects against oxidative stress in Caco-2 cells | Q43805476 | ||
| Uric acid concentration in subjects at risk of type 2 diabetes mellitus: relationship to components of the metabolic syndrome | Q43911594 | ||
| Survival rate of desmodontal cells in relation to their extraoral dehydration | Q44283942 | ||
| Green tea is neuroprotective in diabetic retinopathy. | Q44462308 | ||
| Effects of antioxidants in diabetes-induced oxidative stress in the glomeruli of diabetic rats | Q44521372 | ||
| Endoplasmic reticulum stress contributes to prediabetic peripheral neuropathy | Q44562750 | ||
| Reactive oxygen species from mitochondria induce cyclooxygenase-2 gene expression in human mesangial cells: potential role in diabetic nephropathy | Q44599806 | ||
| Role of poly(ADP-ribose) polymerase activation in diabetic neuropathy | Q44779266 | ||
| Interrelated effects of insulin and glucose on diacylglycerol-protein kinase-C signalling in rat adipocytes and solei muscle in vitro and in vivo in diabetic rats | Q44870510 | ||
| Biguanide related compounds in traditional antidiabetic functional foods | Q45785612 | ||
| Hyperinsulinemic-euglycemic clamp to assess insulin sensitivity in vivo. | Q45979025 | ||
| Induction of heme oxygenase-1 by plant extract KIOM-79 via Akt pathway and NF-E2 related factor 2 in pancreatic beta-cells | Q46055090 | ||
| Nrf2-dependent upregulation of antioxidative enzymes: a novel pathway for proteasome inhibitor-mediated cardioprotection | Q46058228 | ||
| Age-accelerated atherosclerosis correlates with failure to upregulate antioxidant genes | Q46098709 | ||
| Nrf2-mediated liver protection by esculentoside A against acetaminophen toxicity through the AMPK/Akt/GSK3β pathway | Q46372091 | ||
| Salidroside protects rat liver against ischemia/reperfusion injury by regulating the GSK-3β/Nrf2-dependent antioxidant response and mitochondrial permeability transition | Q46382849 | ||
| Effects of blueberry anthocyanins on retinal oxidative stress and inflammation in diabetes through Nrf2/HO-1 signaling | Q46459740 | ||
| Resveratrol upregulates heme oxygenase-1 expression via activation of NF-E2-related factor 2 in PC12 cells | Q46481176 | ||
| Role of PI3K/Akt and MEK/ERK signaling pathways in sulforaphane- and erucin-induced phase II enzymes and MRP2 transcription, G2/M arrest and cell death in Caco-2 cells | Q46492551 | ||
| The Ins2Akita mouse as a model of early retinal complications in diabetes | Q46508398 | ||
| β-Lapachone increases phase II antioxidant enzyme expression via NQO1-AMPK/PI3K-Nrf2/ARE signaling in rat primary astrocytes | Q46540213 | ||
| Green tea polyphenols and dietary fibre protect against kidney damage in rats with diabetic nephropathy | Q46559893 | ||
| Prevention of diabetic nephropathy in rats through enhanced renal antioxidative capacity by inhibition of the proteasome | Q46574591 | ||
| Directly interact with Keap1 and LPS is involved in the anti-inflammatory mechanisms of (-)-epicatechin-3-gallate in LPS-induced macrophages and endotoxemia. | Q46595666 | ||
| Phycocyanin prevents methylglyoxal-induced mitochondrial-dependent apoptosis in INS-1 cells by Nrf2. | Q46605772 | ||
| Heme oxygenase-1-derived bilirubin protects endothelial cells against high glucose-induced damage | Q46666519 | ||
| Lutein suppresses inflammatory responses through Nrf2 activation and NF-κB inactivation in lipopolysaccharide-stimulated BV-2 microglia | Q46723377 | ||
| NF-E2-related factor 2 inhibits lipid accumulation and oxidative stress in mice fed a high-fat diet. | Q46748175 | ||
| 3,4-Dihydroxyphenylacetic acid, a microbiota-derived metabolite of quercetin, protects against pancreatic β-cells dysfunction induced by high cholesterol | Q46748191 | ||
| Combating oxidative stress in diabetic complications with Nrf2 activators: how much is too much? | Q38190096 | ||
| The Nrf2 regulatory network provides an interface between redox and intermediary metabolism | Q38197467 | ||
| Targeting Nrf2-Keap1 signaling for chemoprevention of skin carcinogenesis with bioactive phytochemicals | Q38215938 | ||
| Diabetes, oxidative stress and therapeutic strategies | Q38218198 | ||
| Taurine ameliorates neuropathy via regulating NF-κB and Nrf2/HO-1 signaling cascades in diabetic rats | Q38218424 | ||
| Role of the Keap1-Nrf2 pathway in cancer | Q38224114 | ||
| A molecular web: endoplasmic reticulum stress, inflammation, and oxidative stress. | Q38239644 | ||
| Anthocyanins as a potential therapy for diabetic retinopathy | Q38241451 | ||
| Vascular oxidative stress, nitric oxide and atherosclerosis | Q38253137 | ||
| Endoplasmic reticulum stress is involved in the connection between inflammation and autophagy in type 2 diabetes | Q38254684 | ||
| Aldose reductase in the etiology of diabetic complications. 3. Neuropathy | Q38256991 | ||
| Mechanisms of diabetic neuron damage: Molecular pathways | Q38269662 | ||
| The emerging role of redox-sensitive Nrf2-Keap1 pathway in diabetes | Q38275209 | ||
| Recent advances in understanding the role of oxidative stress in diabetic neuropathy | Q38282396 | ||
| The Keap1-Nrf2 system and diabetes mellitus | Q38295391 | ||
| Plumericin inhibits proliferation of vascular smooth muscle cells by blocking STAT3 signaling via S-glutathionylation | Q38302272 | ||
| Activation of mitogen-activated protein kinase pathways induces antioxidant response element-mediated gene expression via a Nrf2-dependent mechanism | Q38308355 | ||
| Identification of Nrf2-regulated genes induced by chemopreventive isothiocyanate PEITC by oligonucleotide microarray | Q38311648 | ||
| Role of protein kinase C delta in curcumin-induced antioxidant response element-mediated gene expression in human monocytes. | Q38316154 | ||
| Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival | Q38359163 | ||
| Pancreatic β-cell identity, glucose sensing and the control of insulin secretion. | Q38361859 | ||
| Suppression of Nrf2 attenuates adipogenesis and decreases FGF21 expression through PPAR gamma in 3T3-L1 cells. | Q38406322 | ||
| Structural and functional characterization of Nrf2 degradation by glycogen synthase kinase 3/β-TrCP. | Q38456402 | ||
| Sulforaphane protects against cytokine- and streptozotocin-induced beta-cell damage by suppressing the NF-kappaB pathway | Q38497459 | ||
| Endoplasmic reticulum stress and Nrf2 signaling in cardiovascular diseases | Q38519193 | ||
| The antioxidant function of sestrins is mediated by promotion of autophagic degradation of Keap1 and Nrf2 activation and by inhibition of mTORC1. | Q38539085 | ||
| Functional polymorphisms in Nrf2: implications for human disease. | Q38539087 | ||
| Morin activates the Nrf2-ARE pathway and reduces oxidative stress-induced DNA damage in pancreatic beta cells | Q38715751 | ||
| Diabetes and cancer, common threads and missing links | Q38734687 | ||
| Hidden targets of ubiquitin proteasome system: To prevent diabetic nephropathy | Q38736968 | ||
| An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans | Q38752732 | ||
| Berberine, a natural antidiabetes drug, attenuates glucose neurotoxicity and promotes Nrf2-related neurite outgrowth. | Q39108936 | ||
| Endoplasmic Reticulum (ER) Stress and Endocrine Disorders. | Q39139204 | ||
| Putative protective role of lutein and zeaxanthin in diabetic retinopathy | Q39148545 | ||
| Evaluation of the effect of curcumin capsules on glyburide therapy in patients with type-2 diabetes mellitus. | Q39156724 | ||
| The resveratrol derivatives trans-3,5-dimethoxy-4-fluoro-4'-hydroxystilbene and trans-2,4',5-trihydroxystilbene decrease oxidative stress and prolong lifespan in Caenorhabditis elegans | Q39157134 | ||
| RXRα inhibits the NRF2-ARE signaling pathway through a direct interaction with the Neh7 domain of NRF2. | Q39161771 | ||
| Natural antioxidants in the treatment and prevention of diabetic nephropathy; a potential approach that warrants clinical trials. | Q39169974 | ||
| Epigenetic reactivation of Nrf2 in murine prostate cancer TRAMP C1 cells by natural phytochemicals Z-ligustilide and Radix angelica sinensis via promoter CpG demethylation. | Q39188471 | ||
| Sulforaphane enhances Nrf2 expression in prostate cancer TRAMP C1 cells through epigenetic regulation. | Q39193275 | ||
| Prevention by sulforaphane of diabetic cardiomyopathy is associated with up-regulation of Nrf2 expression and transcription activation | Q39204026 | ||
| Nrf2: a potential therapeutic target for diabetic neuropathy | Q39206295 | ||
| Diabetes-induced impairment in visual function in mice: contributions of p38 MAPK, rage, leukocytes, and aldose reductase | Q39238006 | ||
| Hormetic shifting of redox environment by pro-oxidative resveratrol protects cells against stress | Q39295501 | ||
| Copper diethyldithiocarbamate as an activator of Nrf2 in cultured vascular endothelial cells | Q39301184 | ||
| The KEAP1-NRF2 System in Cancer | Q39317112 | ||
| Influencing of antioxidants' gene variants on risk of diabetes mellitus and its complications: a systematic review | Q39332569 | ||
| Role of Endoplasmic Reticulum Stress, Autophagy, and Inflammation in Cardiovascular Disease | Q39335880 | ||
| Ezetimibe, an NPC1L1 inhibitor, is a potent Nrf2 activator that protects mice from diet-induced nonalcoholic steatohepatitis | Q39383977 | ||
| Novel protective mechanism of reducing renal cell damage in diabetes: Activation AMPK by AICAR increased NRF2/OGG1 proteins and reduced oxidative DNA damage | Q39407505 | ||
| Nrf2 and NF-κB modulation by sulforaphane counteracts multiple manifestations of diabetic neuropathy in rats and high glucose-induced changes | Q39453625 | ||
| Stimulation of GSH synthesis to prevent oxidative stress-induced apoptosis by hydroxytyrosol in human retinal pigment epithelial cells: activation of Nrf2 and JNK-p62/SQSTM1 pathways | Q39470258 | ||
| Pharmacodynamics of curcumin as DNA hypomethylation agent in restoring the expression of Nrf2 via promoter CpGs demethylation. | Q39501191 | ||
| Metabolic stress response implicated in diabetic retinopathy: the role of calpain, and the therapeutic impact of calpain inhibitor | Q39554740 | ||
| SCF/{beta}-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner. | Q39606140 | ||
| Renoprotective effects of (+)-catechin in streptozotocin-induced diabetic rat model | Q39609509 | ||
| Grape seed proanthocyanidin extract protects the retina against early diabetic injury by activating the Nrf2 pathway | Q39652240 | ||
| Long‐acting genipin derivative protects retinal ganglion cells from oxidative stress models in vitro and in vivo through the Nrf2/antioxidant response element signaling pathway | Q39672133 | ||
| Piceatannol induces heme oxygenase-1 expression in human mammary epithelial cells through activation of ARE-driven Nrf2 signaling | Q39691488 | ||
| The major green tea polyphenol, (-)-epigallocatechin-3-gallate, induces heme oxygenase in rat neurons and acts as an effective neuroprotective agent against oxidative stress. | Q39722953 | ||
| α-Tocopherol is an effective Phase II enzyme inducer: protective effects on acrolein-induced oxidative stress and mitochondrial dysfunction in human retinal pigment epithelial cells | Q39739875 | ||
| Inhibition of liver fibrosis by solubilized coenzyme Q10: Role of Nrf2 activation in inhibiting transforming growth factor-beta1 expression | Q39818094 | ||
| Nonhuman primate models of atherosclerosis: potential for the study of diabetes mellitus and hyperinsulinemia | Q39835554 | ||
| Synthetic triterpenoids attenuate cytotoxic retinal injury: cross-talk between Nrf2 and PI3K/AKT signaling through inhibition of the lipid phosphatase PTEN. | Q39843104 | ||
| Activation of NF-E2-related factor-2 reverses biochemical dysfunction of endothelial cells induced by hyperglycemia linked to vascular disease | Q39960465 | ||
| Projection of diabetic retinopathy and other major eye diseases among people with diabetes mellitus: United States, 2005-2050. | Q40020452 | ||
| Diabetes and its link with cancer: providing the fuel and spark to launch an aggressive growth regime. | Q40037417 | ||
| Activated AMPK boosts the Nrf2/HO-1 signaling axis--A role for the unfolded protein response | Q36055760 | ||
| Diabetic neuropathies: a statement by the American Diabetes Association | Q36081316 | ||
| Inhibition of nitric oxide and inflammatory cytokines in LPS-stimulated murine macrophages by resveratrol, a potent proteasome inhibitor | Q36086859 | ||
| Expression of transforming growth factor beta is elevated in human and experimental diabetic nephropathy | Q36133581 | ||
| Inhibition of high glucose-induced inflammatory response and macrophage infiltration by a novel curcumin derivative prevents renal injury in diabetic rats | Q36159004 | ||
| Structural and functional characterization of Nrf2 degradation by the glycogen synthase kinase 3/β-TrCP axis | Q36172880 | ||
| Identification of novel NRF2-regulated genes by ChIP-Seq: influence on retinoid X receptor alpha. | Q36180243 | ||
| Dissecting molecular cross-talk between Nrf2 and NF-κB response pathways | Q36184638 | ||
| Discovery of the first dual GSK3β inhibitor/Nrf2 inducer. A new multitarget therapeutic strategy for Alzheimer's disease | Q36329594 | ||
| Deficiency in the nuclear factor E2-related factor 2 renders pancreatic β-cells vulnerable to arsenic-induced cell damage | Q36339374 | ||
| Sulforaphane inhibits multiple inflammasomes through an Nrf2-independent mechanism | Q36356987 | ||
| Transcription factor NF-kappaB: a sensor for smoke and stress signals | Q36357810 | ||
| Sulforaphane prevention of diabetes-induced aortic damage was associated with the up-regulation of Nrf2 and its down-stream antioxidants | Q36392375 | ||
| Nrf2: a potential molecular target for cancer chemoprevention by natural compounds | Q36399767 | ||
| Sulforaphane reduces hepatic glucose production and improves glucose control in patients with type 2 diabetes. | Q36405748 | ||
| Enhanced Nrf2 activity worsens insulin resistance, impairs lipid accumulation in adipose tissue, and increases hepatic steatosis in leptin-deficient mice. | Q36410781 | ||
| Oxidative reactive species in cell injury: Mechanisms in diabetes mellitus and therapeutic approaches | Q36420078 | ||
| Identification of novel microRNAs in post-transcriptional control of Nrf2 expression and redox homeostasis in neuronal, SH-SY5Y cells | Q36454075 | ||
| Vitamin E, Its Beneficial Role in Diabetes Mellitus (DM) and Its Complications | Q36554069 | ||
| Adipose deficiency of Nrf2 in ob/ob mice results in severe metabolic syndrome | Q36635251 | ||
| Endoplasmic reticulum stress plays a key role in the pathogenesis of diabetic peripheral neuropathy | Q36635295 | ||
| Early visual deficits in streptozotocin-induced diabetic long evans rats | Q36683611 | ||
| Polymorphisms in the transcription factor NRF2 and forearm vasodilator responses in humans. | Q36689545 | ||
| Proteomic analysis of ubiquitin ligase KEAP1 reveals associated proteins that inhibit NRF2 ubiquitination | Q36745578 | ||
| Zinc protects against diabetes-induced pathogenic changes in the aorta: roles of metallothionein and nuclear factor (erythroid-derived 2)-like 2. | Q36753482 | ||
| Dietary curcumin significantly improves obesity-associated inflammation and diabetes in mouse models of diabesity | Q36755382 | ||
| Reactive carbonyls and oxidative stress: potential for therapeutic intervention | Q36849897 | ||
| Transcription factor Nrf2-mediated antioxidant defense system in the development of diabetic retinopathy | Q36911967 | ||
| Liver carcinogenesis: from naughty chemicals to soothing fat and the surprising role of NRF2. | Q36927013 | ||
| Genetic Polymorphisms of Transcription Factor NRF2 and of its Host Gene Sulfiredoxin (SRXN1) are Associated with Cerebrovascular Disease in a Finnish Cohort, the TAMRISK Study | Q36934471 | ||
| Identification and functional studies of a new Nrf2 partner IQGAP1: a critical role in the stability and transactivation of Nrf2. | Q36945767 | ||
| Novel role of curcumin in the prevention of cytokine-induced islet death in vitro and diabetogenesis in vivo | Q36977456 | ||
| A glimpse of various pathogenetic mechanisms of diabetic nephropathy | Q36979205 | ||
| Molecular understanding of hyperglycemia's adverse effects for diabetic complications | Q35005662 | ||
| Keap1-knockdown decreases fasting-induced fatty liver via altered lipid metabolism and decreased fatty acid mobilization from adipose tissue | Q35041508 | ||
| Screening of natural compounds as activators of the keap1-nrf2 pathway | Q35059810 | ||
| A new view of diabetic retinopathy: a neurodegenerative disease of the eye. | Q35092253 | ||
| New Insights on Oxidative Stress and Diabetic Complications May Lead to a “Causal” Antioxidant Therapy | Q35115544 | ||
| Combination therapy with oleanolic acid and metformin as a synergistic treatment for diabetes | Q35151581 | ||
| The Epigenetic Impact of Cruciferous Vegetables on Cancer Prevention | Q35163136 | ||
| The cyclopentenone prostaglandin 15d-PGJ2 inhibits the NLRP1 and NLRP3 inflammasomes | Q35163583 | ||
| Diabetes and cancer: A critical appraisal of the pathogenetic and therapeutic links | Q35179959 | ||
| Nrf2 represses FGF21 during long-term high-fat diet-induced obesity in mice | Q35227185 | ||
| Beneficial role of Nrf2 in regulating NADPH generation and consumption | Q35231072 | ||
| Protection against phalloidin-induced liver injury by oleanolic acid involves Nrf2 activation and suppression of Oatp1b2. | Q35243790 | ||
| Advanced glycation end products and oxidative stress in type 2 diabetes mellitus | Q35255473 | ||
| Therapeutic potential of Nrf2 activators in streptozotocin-induced diabetic nephropathy | Q35404877 | ||
| Protective Role of Nuclear Factor E2-Related Factor 2 against Acute Oxidative Stress-Induced Pancreatic β -Cell Damage. | Q35531066 | ||
| miR-200a regulates Nrf2 activation by targeting Keap1 mRNA in breast cancer cells | Q35562532 | ||
| Therapeutic approaches to target inflammation in type 2 diabetes | Q35581498 | ||
| PKCε-CREB-Nrf2 signalling induces HO-1 in the vascular endothelium and enhances resistance to inflammation and apoptosis | Q35606379 | ||
| Oxidative stress as a therapeutic target in diabetes: revisiting the controversy | Q35621286 | ||
| Resveratrol analog piceatannol restores the palmitic acid-induced impairment of insulin signaling and production of endothelial nitric oxide via activation of anti-inflammatory and antioxidative heme oxygenase-1 in human endothelial cells | Q35628421 | ||
| Preventive effects of green tea (Camellia sinensis var. assamica) on diabetic nephropathy | Q35648209 | ||
| The effect of Nrf2 pathway activation on human pancreatic islet cells | Q35674148 | ||
| Mechanism of Tang Luo Ning effect on attenuating of oxidative stress in sciatic nerve of STZ-induced diabetic rats | Q35740491 | ||
| Fisetin Imparts Neuroprotection in Experimental Diabetic Neuropathy by Modulating Nrf2 and NF-κB Pathways | Q35785534 | ||
| Targeting Nrf2 by dihydro-CDDO-trifluoroethyl amide enhances autophagic clearance and viability of β-cells in a setting of oxidative stress | Q35801045 | ||
| Myeloid deletion of nuclear factor erythroid 2-related factor 2 increases atherosclerosis and liver injury | Q35815261 | ||
| Quercetin Attenuates Inflammatory Responses in BV-2 Microglial Cells: Role of MAPKs on the Nrf2 Pathway and Induction of Heme Oxygenase-1 | Q35822864 | ||
| Peptide and small molecule inhibitors of the Keap1-Nrf2 protein-protein interaction. | Q35836115 | ||
| Therapeutic potential of digitoflavone on diabetic nephropathy: nuclear factor erythroid 2-related factor 2-dependent anti-oxidant and anti-inflammatory effect | Q35884405 | ||
| Anti-diabetic and anti-oxidant potential of aged garlic extract (AGE) in streptozotocin-induced diabetic rats | Q35898381 | ||
| Association between the NF-E2 Related Factor 2 Gene Polymorphism and Oxidative Stress, Anti-Oxidative Status, and Newly-Diagnosed Type 2 Diabetes Mellitus in a Chinese Population | Q35902662 | ||
| Promotion of hepatocellular carcinoma by the intestinal microbiota and TLR4. | Q35903501 | ||
| The role of omega-3 long-chain polyunsaturated fatty acids in health and disease of the retina | Q35957608 | ||
| Curcumin attenuates Nrf2 signaling defect, oxidative stress in muscle and glucose intolerance in high fat diet-fed mice | Q35988139 | ||
| NBR1 and p62 as cargo receptors for selective autophagy of ubiquitinated targets | Q57269938 | ||
| Curcumin prevents experimental diabetic retinopathy in rats through its hypoglycemic, antioxidant, and anti-inflammatory mechanisms | Q57840010 | ||
| Preparing for Precision Medicine | Q58045547 | ||
| Coenzyme Q10 prevents GDP-sensitive mitochondrial uncoupling, glomerular hyperfiltration and proteinuria in kidneys from db/db mice as a model of type 2 diabetes | Q58329660 | ||
| Susceptibility of Nrf2-null mice to steatohepatitis and cirrhosis upon consumption of a high-fat diet is associated with oxidative stress, perturbation of the unfolded protein response, and disturbance in the expression of metabolic enzymes but not w | Q59654517 | ||
| De-Meaning of Metabolism | Q60155821 | ||
| The metabolism and excretion of curcumin (1,7-bis-(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) in the rat | Q67425679 | ||
| Role of glucose and insulin resistance in development of type 2 diabetes mellitus: results of a 25-year follow-up study | Q67521964 | ||
| Fatty acid composition of the human macula and peripheral retina | Q67964940 | ||
| Vegetable consumption and lung cancer risk: a population-based case-control study in Hawaii | Q69352332 | ||
| Lipid peroxidation and retinal degeneration | Q70998879 | ||
| Hyperglycemia and intestinal and renal glucose transport: implications for diabetic renal injury | Q71717662 | ||
| Oxidative protein damage in early stage Type 1 diabetic patients | Q73270735 | ||
| Oxidative protein damage in plasma of type 2 diabetic patients | Q73570418 | ||
| Diabetic retinopathy | Q75217418 | ||
| Nutrient control of insulin secretion in isolated normal human islets | Q79386786 | ||
| [Effects of grape seed proanthocyanidins extracts on experimental diabetic nephropathy in rats] | Q79752423 | ||
| Loss of cholinergic and dopaminergic amacrine cells in streptozotocin-diabetic rat and Ins2Akita-diabetic mouse retinas | Q79786378 | ||
| Oral bioavailability of curcumin in rat and the herbal analysis from Curcuma longa by LC-MS/MS | Q80075359 | ||
| A dominant function of IKK/NF-kappaB signaling in global lipopolysaccharide-induced gene expression | Q80128965 | ||
| Action of Nrf2 and Keap1 in ARE-mediated NQO1 expression by quercetin | Q80225202 | ||
| Upregulation of thioredoxin system via Nrf2-antioxidant responsive element pathway in adaptive-retinal neuroprotection in vivo and in vitro | Q80356068 | ||
| Effect of curcumin on hyperglycemia-induced vascular endothelial growth factor expression in streptozotocin-induced diabetic rat retina | Q80698586 | ||
| Absolute bioavailability and dose-dependent pharmacokinetic behaviour of dietary doses of the chemopreventive isothiocyanate sulforaphane in rat | Q81295491 | ||
| Curcumin attenuates insulin resistance in hepatocytes by inducing Nrf2 nuclear translocation | Q82176683 | ||
| Melatonin modulates neuroinflammation and oxidative stress in experimental diabetic neuropathy: effects on NF‐κB and Nrf2 cascades | Q82378720 | ||
| Nrf2 is essential for cholesterol crystal-induced inflammasome activation and exacerbation of atherosclerosis | Q83836296 | ||
| Effect of bardoxolone methyl on kidney function in patients with T2D and Stage 3b-4 CKD | Q83917014 | ||
| Pharmacologic induction of heme oxygenase-1 plays a protective role in diabetic retinopathy in rats | Q84283959 | ||
| Effect of addition of silymarin to renin-angiotensin system inhibitors on proteinuria in type 2 diabetic patients with overt nephropathy: a randomized, double-blind, placebo-controlled trial | Q84538317 | ||
| Nrf2-ARE signaling pathway and natural products for cancer chemoprevention | Q84575827 | ||
| Nrf2 induces fibroblast growth factor 21 in diabetic mice | Q85654740 | ||
| Type 2 diabetes | Q89258111 | ||
| Precision diabetes: learning from monogenic diabetes | Q33453490 | ||
| Phosphorylation of Nrf2 at multiple sites by MAP kinases has a limited contribution in modulating the Nrf2-dependent antioxidant response | Q33492309 | ||
| Nrf2 expression is regulated by epigenetic mechanisms in prostate cancer of TRAMP mice | Q33523039 | ||
| Nuclear factor (erythroid-derived 2)-like 2 regulates drug resistance in pancreatic cancer cells | Q33527780 | ||
| Diabetic peripheral neuropathies: their cost to patient and society and the value of knowledge of risk factors for development of interventions | Q33534160 | ||
| Diabetic neuropathy: mechanisms to management | Q33554384 | ||
| Neuroinflammation and oxidative stress in diabetic neuropathy: futuristic strategies based on these targets. | Q33614346 | ||
| An internal ribosomal entry site mediates redox-sensitive translation of Nrf2. | Q33633725 | ||
| Metformin is associated with survival benefit in pancreatic cancer patients with diabetes: a systematic review and meta-analysis | Q33648824 | ||
| Identification of a common chemical signal regulating the induction of enzymes that protect against chemical carcinogenesis | Q33665840 | ||
| Polymorphism of Nrf2, an antioxidative gene, is associated with blood pressure and cardiovascular mortality in hemodialysis patients | Q33712021 | ||
| Zeaxanthin induces Nrf2-mediated phase II enzymes in protection of cell death | Q33720330 | ||
| ROS signaling, oxidative stress and Nrf2 in pancreatic beta-cell function | Q33724561 | ||
| Expression and functional assessment of candidate type 2 diabetes susceptibility genes identify four new genes contributing to human insulin secretion | Q33726555 | ||
| The protective role of Nrf2 in streptozotocin-induced diabetic nephropathy | Q33750711 | ||
| Nuclear factor erythroid 2-related factor 2 deletion impairs glucose tolerance and exacerbates hyperglycemia in type 1 diabetic mice. | Q33755271 | ||
| NFE2L2 polymorphisms, mortality, and metabolism in the general population | Q33764879 | ||
| Age-related changes in redox signaling and VSMC function | Q33830145 | ||
| Dimethylfumarate attenuates restenosis after acute vascular injury by cell-specific and Nrf2-dependent mechanisms | Q33865212 | ||
| Mechanisms of insulin resistance after insulin-induced hypoglycemia in humans: the role of lipolysis | Q33869737 | ||
| Dietary Lycium barbarum polysaccharide induces Nrf2/ARE pathway and ameliorates insulin resistance induced by high-fat via activation of PI3K/AKT signaling. | Q33871538 | ||
| Age-related retinopathy in NRF2-deficient mice. | Q33894963 | ||
| Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2 | Q33900511 | ||
| Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2. | Q33994850 | ||
| NF-E2–Related Factor 2 Promotes Atherosclerosis by Effects on Plasma Lipoproteins and Cholesterol Transport That Overshadow Antioxidant Protection | Q28295706 | ||
| Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin | Q28300614 | ||
| Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2 | Q28382872 | ||
| When NRF2 talks, who's listening? | Q28384223 | ||
| Hrd1 suppresses Nrf2-mediated cellular protection during liver cirrhosis | Q28385517 | ||
| Small molecule modulators of Keap1-Nrf2-ARE pathway as potential preventive and therapeutic agents | Q28386244 | ||
| Nuclear factor E2-related factor-2 (Nrf2) is required for NLRP3 and AIM2 inflammasome activation | Q28387955 | ||
| Stabilization of endogenous Nrf2 by minocycline protects against Nlrp3-inflammasome induced diabetic nephropathy | Q28391260 | ||
| p62 links autophagy and Nrf2 signaling | Q28392820 | ||
| Sulforaphane Protects against Cardiovascular Disease via Nrf2 Activation | Q28393421 | ||
| Resveratrol protects against methylglyoxal-induced hyperglycemia and pancreatic damage in vivo | Q28393675 | ||
| Association of Nuclear Factor-Erythroid 2-Related Factor 2, Thioredoxin Interacting Protein, and Heme Oxygenase-1 Gene Polymorphisms with Diabetes and Obesity in Mexican Patients | Q28394464 | ||
| Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription | Q28395088 | ||
| Molecular and Cellular Mechanisms of Cardiovascular Disorders in Diabetes | Q28395675 | ||
| Metformin induces a dietary restriction-like state and the oxidative stress response to extend C. elegans Healthspan via AMPK, LKB1, and SKN-1 | Q28472548 | ||
| Effect of graded Nrf2 activation on phase-I and -II drug metabolizing enzymes and transporters in mouse liver | Q28481289 | ||
| Impaired liver regeneration in Nrf2 knockout mice: role of ROS-mediated insulin/IGF-1 resistance | Q28505114 | ||
| Keap1-Independent Regulation of Nrf2 Activity by Protein Acetylation and a BET Bromodomain Protein | Q28552496 | ||
| Effects of curcumin on retinal oxidative stress and inflammation in diabetes | Q28567589 | ||
| Inhibition of NADPH oxidase prevents advanced glycation end product-mediated damage in diabetic nephropathy through a protein kinase C-alpha-dependent pathway | Q28571271 | ||
| The antioxidant defense system Keap1-Nrf2 comprises a multiple sensing mechanism for responding to a wide range of chemical compounds | Q28755952 | ||
| Induction of Nrf2/ARE-mediated cytoprotective genes by red ginseng oil through ASK1-MKK4/7-JNK and p38 MAPK signaling pathways in HepG2 cells | Q28822455 | ||
| Nrf2-Mediated Regulation of Skeletal Muscle Glycogen Metabolism | Q28829068 | ||
| Role of Nrf2 and protective effects of Metformin against tobacco smoke-induced cerebrovascular toxicity | Q29247988 | ||
| Oxidative Stress and Diabetic Complications | Q29615423 | ||
| Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage | Q29616101 | ||
| Inflammasomes in health and disease | Q29616356 | ||
| Oxidative stress, inflammation, and cancer: how are they linked? | Q29616835 | ||
| Immunological and inflammatory functions of the interleukin-1 family | Q29619669 | ||
| Type 1 diabetes mellitus | Q30235021 | ||
| Nuclear Factor (Erythroid-Derived 2)-Like 2 and Thioredoxin-1 in Atherosclerosis and Ischemia/Reperfusion Injury in the Heart | Q30275291 | ||
| Nrf2 deficiency in myeloid cells is not sufficient to protect mice from high-fat diet-induced adipose tissue inflammation and insulin resistance | Q30419533 | ||
| Astrocyte NMDA receptors' activity sustains neuronal survival through a Cdk5-Nrf2 pathway. | Q30678012 | ||
| Lignans Extracted from Eucommia Ulmoides Oliv. Protects Against AGEs-Induced Retinal Endothelial Cell Injury | Q32186350 | ||
| Xanthohumol isolated from Humulus lupulus Inhibits menadione-induced DNA damage through induction of quinone reductase. | Q33221662 | ||
| Screening method for the discovery of potential cancer chemoprevention agents based on mass spectrometric detection of alkylated Keap1. | Q33224234 | ||
| Reactive oxygen species as a signal in glucose-stimulated insulin secretion | Q33280759 | ||
| ??? | Q28204243 | ||
| The pancreatic beta cell. Structure and function | Q40041462 | ||
| Nrf2-mediated haeme oxygenase-1 up-regulation induced by cobalt protoporphyrin has antinociceptive effects against inflammatory pain in the formalin test in mice | Q40061304 | ||
| Hyperglycemia decreases mitochondrial function: the regulatory role of mitochondrial biogenesis. | Q40087204 | ||
| Preconditioning of H2S inhalation protects against cerebral ischemia/reperfusion injury by induction of HSP70 through PI3K/Akt/Nrf2 pathway | Q40102686 | ||
| Salvianolic acid B protects against acetaminophen hepatotoxicity by inducing Nrf2 and phase II detoxification gene expression via activation of the PI3K and PKC signaling pathways | Q40167458 | ||
| Glycogen synthase kinase-3beta inhibits the xenobiotic and antioxidant cell response by direct phosphorylation and nuclear exclusion of the transcription factor Nrf2. | Q40301567 | ||
| The Ecstasy and Agony of Assay Interference Compounds. | Q40314472 | ||
| Glucoraphanin Ameliorates Obesity and Insulin Resistance Through Adipose Tissue Browning and Reduction of Metabolic Endotoxemia in Mice | Q40328936 | ||
| Flavonoids protect retinal ganglion cells from oxidative stress-induced death | Q40348410 | ||
| Lipopolysaccharide-induced heme oxygenase-1 expression in human monocytic cells is mediated via Nrf2 and protein kinase C. | Q40370342 | ||
| Specific patterns of electrophile adduction trigger Keap1 ubiquitination and Nrf2 activation | Q40403963 | ||
| Pterocarpus marsupium extract (Vijayasar) prevented the alteration in metabolic patterns induced in the normal rat by feeding an adequate diet containing fructose as sole carbohydrate | Q40414242 | ||
| Smad3-ATF3 signaling mediates TGF-beta suppression of genes encoding Phase II detoxifying proteins. | Q40475326 | ||
| Physiologic relevance of heterogeneity in the pancreatic beta-cell population | Q40569649 | ||
| Inflammation-induced ROS generation causes pancreatic cell death through modulation of Nrf2/NF-κB and SAPK/JNK pathway. | Q40720666 | ||
| Ester bond-containing tea polyphenols potently inhibit proteasome activity in vitro and in vivo | Q40817505 | ||
| A polymorphism in a major antioxidant gene (Kelch-like ECH-associated protein 1) predicts incident cardiovascular events in chronic kidney disease patients: an exploratory study. | Q40855330 | ||
| Rutin ameliorates diabetic neuropathy by lowering plasma glucose and decreasing oxidative stress via Nrf2 signaling pathway in rats | Q40863629 | ||
| IPF1, a homeodomain-containing transactivator of the insulin gene | Q40874284 | ||
| Rapamycin regulates macrophage activation by inhibiting NLRP3 inflammasome-p38 MAPK-NFκB pathways in autophagy- and p62-dependent manners | Q41092652 | ||
| Mechanistic studies on the inactivation of the proteasome by lactacystin: a central role for clasto-lactacystin beta-lactone | Q41213327 | ||
| Altered protein glycosylation of rat 3Y1 cells induced by activated c-myc gene | Q41684391 | ||
| Active NF-E2-related factor (Nrf2) contributes to keep endothelial NO synthase (eNOS) in the coupled state: role of reactive oxygen species (ROS), eNOS, and heme oxygenase (HO-1) levels. | Q41776091 | ||
| CuZn-superoxide dismutase, Mn-superoxide dismutase, catalase and glutathione peroxidase in pancreatic islets and other tissues in the mouse. | Q41827087 | ||
| Curcumin ameliorates macrophage infiltration by inhibiting NF-κB activation and proinflammatory cytokines in streptozotocin induced-diabetic nephropathy. | Q41854992 | ||
| Metformin directly acts on mitochondria to alter cellular bioenergetics. | Q41897802 | ||
| Spatial frequency threshold and contrast sensitivity of an optomotor behavior are impaired in the Ins2Akita mouse model of diabetes | Q42081969 | ||
| Diabetic retinopathy is associated with oxidative stress and mitigation of gene expression of antioxidant enzymes | Q42113527 | ||
| Rationale and trial design of Bardoxolone Methyl Evaluation in Patients with Chronic Kidney Disease and Type 2 Diabetes: the Occurrence of Renal Events (BEACON). | Q42272174 | ||
| Precision medicine for managing diabetes | Q42346029 | ||
| Transcription factors Hsf1 and Nrf2 engage in crosstalk for cytoprotection. | Q42469610 | ||
| Effect of green tea on kidney tubules of diabetic rats. | Q46770553 | ||
| Epigalloccatechin-3-gallate inhibits ocular neovascularization and vascular permeability in human retinal pigment epithelial and human retinal microvascular endothelial cells via suppression of MMP-9 and VEGF activation | Q46852214 | ||
| Identification of sensor cysteines in human Keap1 modified by the cancer chemopreventive agent sulforaphane | Q46854767 | ||
| Upregulation of heme oxygenase-1 by Epigallocatechin-3-gallate via the phosphatidylinositol 3-kinase/Akt and ERK pathways | Q46868852 | ||
| Gene expression profiles induced by cancer chemopreventive isothiocyanate sulforaphane in the liver of C57BL/6J mice and C57BL/6J/Nrf2 (-/-) mice | Q46974887 | ||
| Nrf2 protects pancreatic β-cells from oxidative and nitrosative stress in diabetic model mice | Q46975887 | ||
| Chrysobalanus icaco L. Leaves Normalizes Insulin Sensitivity and Blood Glucose and Inhibits Weight Gain in High-Fat Diet-Induced Obese Mice | Q47327275 | ||
| Pathogenesis, prevention, and treatment of diabetic nephropathy | Q47770839 | ||
| Oxidative retinal products and ocular damages in diabetic patients | Q47782848 | ||
| Activating or Inhibiting Nrf2? | Q47832612 | ||
| Induction of IAPP amyloid deposition and associated diabetic abnormalities by a prion-like mechanism | Q48002458 | ||
| Nrf2 Improves Leptin and Insulin Resistance Provoked by Hypothalamic Oxidative Stress. | Q48297176 | ||
| Cancer risk among people with type 1 and type 2 diabetes: disentangling true associations, detection bias, and reverse causation | Q48419381 | ||
| Pre-treatment with metformin activates Nrf2 antioxidant pathways and inhibits inflammatory responses through induction of AMPK after transient global cerebral ischemia. | Q48451001 | ||
| RD Lawrence lecture 2013. Stratified approaches to the management of diabetes | Q48524869 | ||
| Metallothionein Is Downstream of Nrf2 and Partially Mediates Sulforaphane Prevention of Diabetic Cardiomyopathy | Q49783549 | ||
| Protective effects of epigallocatechin gallate (EGCG) on streptozotocin-induced diabetic nephropathy in mice. | Q50450586 | ||
| Sulforaphane prevents the development of cardiomyopathy in type 2 diabetic mice probably by reversing oxidative stress-induced inhibition of LKB1/AMPK pathway. | Q50459301 | ||
| Signaling pathways activated by the phytochemical nordihydroguaiaretic acid contribute to a Keap1-independent regulation of Nrf2 stability: Role of glycogen synthase kinase-3. | Q50506579 | ||
| The health care costs of diabetic peripheral neuropathy in the US. | Q50719755 | ||
| Nrf2 as molecular target for polyphenols: A novel therapeutic strategy in diabetic retinopathy. | Q50874501 | ||
| Nigella sativa oil and thymoquinone ameliorate albuminuria and renal extracellular matrix accumulation in the experimental diabetic rats. | Q50879890 | ||
| Attenuation of diabetic nephropathy by Sanziguben Granule inhibiting EMT through Nrf2-mediated anti-oxidative effects in streptozotocin (STZ)-induced diabetic rats. | Q51003797 | ||
| Dihydromyricetin modulates p62 and autophagy crosstalk with the Keap-1/Nrf2 pathway to alleviate ethanol-induced hepatic injury. | Q51051289 | ||
| Role of pterostilbene in attenuating immune mediated devastation of pancreatic beta cells via Nrf2 signaling cascade. | Q51084786 | ||
| Insulin Inhibits Nrf2 Gene Expression via Heterogeneous Nuclear Ribonucleoprotein F/K in Diabetic Mice. | Q51092133 | ||
| The Impact of Resveratrol Supplementation on Blood Glucose, Insulin, Insulin Resistance, Triglyceride, and Periodontal Markers in Type 2 Diabetic Patients with Chronic Periodontitis. | Q51110611 | ||
| Effects of grape seed proanthocyanidin extract on renal injury in type 2 diabetic rats. | Q51313580 | ||
| Synthesis of Keap1-phosphorylated p62 and Keap1-Nrf2 protein-protein interaction inhibitors and their inhibitory activity. | Q51329636 | ||
| Effect of broccoli sprouts on insulin resistance in type 2 diabetic patients: a randomized double-blind clinical trial. | Q51357683 | ||
| Broccoli sprouts powder could improve serum triglyceride and oxidized LDL/LDL-cholesterol ratio in type 2 diabetic patients: a randomized double-blind placebo-controlled clinical trial. | Q51361259 | ||
| Similar reduction of first- and second-phase B-cell responses at three different glucose levels in type II diabetes and the effect of gliclazide therapy. | Q51620127 | ||
| Protective Effects of Coenzyme Q10 Against Hydrogen Peroxide-Induced Oxidative Stress in PC12 Cell: The Role of Nrf2 and Antioxidant Enzymes. | Q51622236 | ||
| Deletion of Nrf2 leads to hepatic insulin resistance via the activation of NF-κB in mice fed a high-fat diet. | Q51697291 | ||
| Quercetin protects human hepatocytes from ethanol-derived oxidative stress by inducing heme oxygenase-1 via the MAPK/Nrf2 pathways. | Q52926548 | ||
| Amelioration of altered antioxidant enzymes activity and glomerulosclerosis by coenzyme Q10 in alloxan-induced diabetic rats. | Q53157164 | ||
| Anti-hyperlipidemic and anti-peroxidative role of pterostilbene via Nrf2 signaling in experimental diabetes. | Q53162677 | ||
| Induction of HO-1 and redox signaling in endothelial cells by advanced glycation end products: a role for Nrf2 in vascular protection in diabetes. | Q53336146 | ||
| Fumaric acid esters prevent the NLRP3 inflammasome-mediated and ATP-triggered pyroptosis of differentiated THP-1 cells. | Q53459121 | ||
| Bardoxolone methyl prevents insulin resistance and the development of hepatic steatosis in mice fed a high-fat diet. | Q53496674 | ||
| Increased number of islet-associated macrophages in type 2 diabetes. | Q53545508 | ||
| Induction of antioxidative Nrf2 gene transcription by coffee in humans: depending on genotype? | Q53668491 | ||
| Sulforaphane ameliorates the insulin responsiveness and the lipid profile but does not alter the antioxidant response in diabetic rats. | Q53725001 | ||
| Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues. | Q53787751 | ||
| Genetic association of NAD(P)H quinone oxidoreductase (NQO1*2) polymorphism with NQO1 levels and risk of diabetic nephropathy. | Q54241709 | ||
| Sulforaphane attenuation of experimental diabetic nephropathy involves GSK-3 beta/Fyn/Nrf2 signaling pathway. | Q54287779 | ||
| Electronegative LDL induction of apoptosis in macrophages: involvement of Nrf2. | Q54450572 | ||
| Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming. | Q54497843 | ||
| Polymorphisms in metallothionein-1 and -2 genes associated with the risk of type 2 diabetes mellitus and its complications. | Q54541622 | ||
| P433 | issue | 6 | |
| P921 | main subject | natural product | Q901227 |
| P304 | page(s) | 1738-1767 | |
| P577 | publication date | 2017-12-28 | |
| P1433 | published in | Biotechnology Advances | Q4915328 |
| P1476 | title | Activation of Nrf2 signaling by natural products-can it alleviate diabetes? | |
| P478 | volume | 36 |
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