Metformin inhibits the migration and invasion of esophageal squamous cell carcinoma cells by downregulating the protein kinase B signaling pathway

scientific article published on 28 December 2017

Metformin inhibits the migration and invasion of esophageal squamous cell carcinoma cells by downregulating the protein kinase B signaling pathway is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3892/OL.2017.7699
P932PMC publication ID5778829
P698PubMed publication ID29435022

P2093author name stringXianbin Cai
Hui Hu
Xi Hu
Xiaojun Tan
Xubin Jing
Qinjia Wang
Binming Chen
Yindi He
Yinghong Guan
P2860cites workAnalysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
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Metformin Induced AMPK Activation, G0/G1 Phase Cell Cycle Arrest and the Inhibition of Growth of Esophageal Squamous Cell Carcinomas In Vitro and In VivoQ35702142
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Modulatory role of garlicin in migration and invasion of intrahepatic cholangiocarcinoma via PI3K/AKT pathwayQ38798466
Heterophyllin B inhibits the adhesion and invasion of ECA-109 human esophageal carcinoma cells by targeting PI3K/AKT/β-catenin signalingQ38813473
Metformin inhibits the invasion of human hepatocellular carcinoma cells and enhances the chemosensitivity to sorafenib through a downregulation of the ERK/JNK-mediated NF-κB-dependent pathway that reduces uPA and MMP-9 expressionQ38954232
Metformin blocks melanoma invasion and metastasis development in AMPK/p53-dependent manner.Q39143352
Antitumor effect of metformin in esophageal cancer: in vitro studyQ39228246
Metformin inhibits the development and metastasis of ovarian cancer.Q39321602
Luteinizing hormone facilitates angiogenesis in ovarian epithelial tumor cells and metformin inhibits the effect through the mTOR signaling pathwayQ39370440
Metformin treatment exerts antiinvasive and antimetastatic effects in human endometrial carcinoma cellsQ39614659
Acacetin inhibits TPA-induced MMP-2 and u-PA expressions of human lung cancer cells through inactivating JNK signaling pathway and reducing binding activities of NF-kappaB and AP-1.Q39701554
NF-kappaB promotes epithelial-mesenchymal transition, migration and invasion of pancreatic carcinoma cellsQ39721374
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Relationship between NF-κB, MMP-9, and MICA expression in pituitary adenomas reveals a new mechanism of pituitary adenomas immune escapeQ48204284
P433issue3
P921main subjectesophageal squamous cell carcinomaQ108442577
metforminQ19484
P304page(s)2939-2945
P577publication date2017-12-28
P1433published inOncology LettersQ20640514
P1476titleMetformin inhibits the migration and invasion of esophageal squamous cell carcinoma cells by downregulating the protein kinase B signaling pathway
P478volume15