scholarly article | Q13442814 |
P50 | author | Changmai Chen | Q85401964 |
P2093 | author name string | Yuan Wang | |
Ivan J Dmochowski | |||
Liangliang Zhang | |||
Jiali Yang | |||
Lijia Yu | |||
Duanwei Liang | |||
Xinjing Tang | |||
Gubu Amu | |||
P2860 | cites work | Off-target effects related to the phosphorothioate modification of nucleic acids. | Q39693685 |
A screen of chemical modifications identifies position-specific modification by UNA to most potently reduce siRNA off-target effects | Q39706132 | ||
Cyclic caged morpholinos: conformationally gated probes of embryonic gene function | Q41881465 | ||
Turning the 10-23 DNAzyme on and off with light | Q42287457 | ||
Synthesis and characterization of small circular double-stranded RNAs | Q42816699 | ||
Dumbbell-shaped nanocircular RNAs for RNA interference | Q42820652 | ||
Highly potent and stable capped siRNAs with picomolar activity for RNA interference | Q44396769 | ||
Tolerance of RNA interference toward modifications of the 5' antisense phosphate of small interfering RNA. | Q50687429 | ||
Asymmetric RNA duplexes mediate RNA interference in mammalian cells. | Q53436494 | ||
Photocaging strategy for functionalisation of oligonucleotides and its applications for oligonucleotide labelling and cyclisation | Q84531333 | ||
Modification of the siRNA passenger strand by 5-nitroindole dramatically reduces its off-target effects | Q84782712 | ||
Locked nucleic acid (LNA) mediated improvements in siRNA stability and functionality | Q24794430 | ||
Argonaute2 is the catalytic engine of mammalian RNAi | Q27860545 | ||
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells | Q27860926 | ||
Two classes of short interfering RNA in RNA silencing | Q28219196 | ||
Current prospects for RNA interference-based therapies | Q28235733 | ||
Natural RNA circles function as efficient microRNA sponges | Q29617892 | ||
Circular RNAs are a large class of animal RNAs with regulatory potency | Q29620042 | ||
Single-cell RNA-seq transcriptome analysis of linear and circular RNAs in mouse preimplantation embryos. | Q30406388 | ||
A universal plasmid library encoding all permutations of small interfering RNA. | Q31146643 | ||
Asymmetric shorter-duplex siRNA structures trigger efficient gene silencing with reduced nonspecific effects | Q33713446 | ||
Off-target effects by siRNA can induce toxic phenotype | Q34703017 | ||
Gene silencing in mammals by small interfering RNAs | Q34931992 | ||
Asymmetric siRNA: new strategy to improve specificity and reduce off-target gene expression | Q35988727 | ||
Improved silencing properties using small internally segmented interfering RNAs | Q36082900 | ||
Strand-specific 5'-O-methylation of siRNA duplexes controls guide strand selection and targeting specificity | Q36400708 | ||
Manipulation of gene expression in zebrafish using caged circular morpholino oligomers. | Q36422235 | ||
Knockdown of TNFR1 by the sense strand of an ICAM-1 siRNA: dissection of an off-target effect | Q36509069 | ||
Caged circular antisense oligonucleotides for photomodulation of RNA digestion and gene expression in cells | Q36668733 | ||
Chemical modification of siRNAs for in vivo use. | Q37331765 | ||
Caged nucleotides/nucleosides and their photochemical biology | Q38153216 | ||
Dynamic Release of Bending Stress in Short dsDNA by Formation of a Kink and Forks | Q38277383 | ||
High affinity nucleic acid aptamers for streptavidin incorporated into bi-specific capture ligands | Q38289432 | ||
Effect of the guide strand 3'-end structure on the gene-silencing potency of asymmetric siRNA. | Q38998025 | ||
Synthesis, structure, and biological activity of dumbbell-shaped nanocircular RNAs for RNA interference | Q39478097 | ||
Improved specificity of gene silencing by siRNAs containing unlocked nucleobase analogs | Q39636192 | ||
P921 | main subject | gene silencing | Q1431332 |
P304 | page(s) | 237-244 | |
P577 | publication date | 2017-12-19 | |
P1433 | published in | Molecular Therapy. Nucleic acids | Q27724110 |
P1476 | title | Circular siRNAs for Reducing Off-Target Effects and Enhancing Long-Term Gene Silencing in Cells and Mice | |
P478 | volume | 10 |
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