Cinacalcet-mediated activation of the CaMKKβ-LKB1-AMPK pathway attenuates diabetic nephropathy in db/db mice by modulation of apoptosis and autophagy

scientific article published on 15 February 2018

Cinacalcet-mediated activation of the CaMKKβ-LKB1-AMPK pathway attenuates diabetic nephropathy in db/db mice by modulation of apoptosis and autophagy is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S41419-018-0324-4
P932PMC publication ID5833853
P698PubMed publication ID29449563

P50authorSungjin ChungQ88626949
P2093author name stringMin Young Kim
Yoon Sik Chang
Tae Woo Kim
Hye Won Kim
Young Soo Kim
Bum Soon Choi
Yong-Soo Kim
Cheol Whee Park
Hyung Wook Kim
Yaeni Kim
Eun Nim Kim
Ji Hee Lim
P2860cites workComplexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascadeQ21245891
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Calcimimetic R-568 and its enantiomer S-568 increase nitric oxide release in human endothelial cellsQ28732422
Maintenance of endothelial guanosine triphosphate cyclohydrolase I ameliorates diabetic nephropathyQ30541115
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The calcimimetic agent KRN 1493 lowers plasma parathyroid hormone and ionized calcium concentrations in patients with chronic renal failure on haemodialysis both on the day of haemodialysis and on the day without haemodialysisQ35826159
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Apical extracellular calcium/polyvalent cation-sensing receptor regulates vasopressin-elicited water permeability in rat kidney inner medullary collecting ductQ37365322
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AMP-activated protein kinase (AMPK) controls the aging process via an integrated signaling networkQ37970212
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Rearrangements of the cytoskeleton and cell contacts induce process formation during differentiation of conditionally immortalized mouse podocyte cell lines.Q41084039
Coenzyme Q10 Improves Lipid Metabolism and Ameliorates Obesity by Regulating CaMKII-Mediated PDE4 InhibitionQ41420644
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Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1α axis in db/db miceQ42715172
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Direct activation of AMP-activated protein kinase stimulates nitric-oxide synthesis in human aortic endothelial cellsQ44468960
AMPK inhibits fatty acid-induced increases in NF-kappaB transactivation in cultured human umbilical vein endothelial cells.Q45123854
Localization of the extracellular Ca2+/polyvalent cation-sensing protein in rat kidneyQ48495009
Calcimimetic, AMG 073, induces relaxation on isolated rat aortaQ50085937
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue3
P921main subjectautophagyQ288322
diabetic nephropathyQ1129105
P304page(s)270
P577publication date2018-02-15
P1433published inCell Death and DiseaseQ2197222
P1476titleCinacalcet-mediated activation of the CaMKKβ-LKB1-AMPK pathway attenuates diabetic nephropathy in db/db mice by modulation of apoptosis and autophagy
P478volume9

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cites work (P2860)
Q92632140Autophagy Function and Regulation in Kidney Disease
Q91900884Chinese Herbal Medicine in Ameliorating Diabetic Kidney Disease via Activating Autophagy
Q91836850Cognitive dysfunction: A growing link between diabetes and Alzheimer's disease
Q92422210Molecular Interactions Between Reactive Oxygen Species and Autophagy in Kidney Disease

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