CCN4/WISP1 controls cutaneous wound healing by modulating proliferation, migration and ECM expression in dermal fibroblasts via α5β1 and TNFα.

scientific article published on 9 January 2018

CCN4/WISP1 controls cutaneous wound healing by modulating proliferation, migration and ECM expression in dermal fibroblasts via α5β1 and TNFα. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.MATBIO.2018.01.004
P932PMC publication ID6015535
P698PubMed publication ID29330021

P50authorEmilio Satoshi HaraQ38804372
P2093author name stringMarian F Young
Mitsuaki Ono
Tina M Kilts
Takuo Kuboki
Hai Pham
Azusa Maeda
Asuka Masaki
Taishi Komori
P2860cites workWISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumorsQ22008485
Proposal for a unified CCN nomenclatureQ24535512
WISP-1 is a Wnt-1- and beta-catenin-responsive oncogeneQ24608963
The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healingQ24633454
WISP-1/CCN4 regulates osteogenesis by enhancing BMP-2 activityQ24635850
WISP1, a pro-mitogenic, pro-survival factor, mediates tumor necrosis factor-alpha (TNF-alpha)-stimulated cardiac fibroblast proliferation but inhibits TNF-alpha-induced cardiomyocyte deathQ24642477
Cell surface receptors for CCN proteinsQ26751449
Interactions of the Extracellular Matrix and Progenitor Cells in Cutaneous Wound HealingQ27015024
Structural basis of BMP signalling inhibition by the cystine knot protein NogginQ27640149
Metalloproteinases: A parade of functions in matrix biology and an outlook for the futureQ28082670
All in the CCN family: essential matricellular signaling modulators emerge from the bunkerQ28275856
CCN4 regulates vascular smooth muscle cell migration and proliferationQ28567429
Positional differences in the wound transcriptome of skin and oral mucosaQ33655612
Epithelial to mesenchymal transition in human skin wound healing is induced by tumor necrosis factor-alpha through bone morphogenic protein-2.Q33816329
Factors affecting wound healingQ33993981
WISP1/CCN4: a potential target for inhibiting prostate cancer growth and spread to boneQ34971961
Decorin interacts with connective tissue growth factor (CTGF)/CCN2 by LRR12 inhibiting its biological activityQ35085132
Revisiting the matricellular conceptQ35233858
WNT1-induced Secreted Protein-1 (WISP1), a Novel Regulator of Bone Turnover and Wnt Signaling.Q35662340
The matricellular protein CCN1 mediates neutrophil efferocytosis in cutaneous wound healingQ35780076
Structural and functional properties of CCN proteinsQ36053014
Tumor necrosis factor α release in peripheral blood mononuclear cells of cutaneous lupus and dermatomyositis patientsQ36084873
Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-betaQ36663630
Fibroblast differentiation in wound healing and fibrosisQ36729100
Targeting the TGFbeta, endothelin-1 and CCN2 axis to combat fibrosis in sclerodermaQ37093118
TNF-alpha production in the skinQ37282420
Signaling in fibrosis: targeting the TGF beta, endothelin-1 and CCN2 axis in scleroderma.Q37501895
Potential therapeutic targets for cardiac fibrosis: TGFbeta, angiotensin, endothelin, CCN2, and PDGF, partners in fibroblast activationQ37764239
WISP 1 is an important survival factor in human mesenchymal stromal cellsQ38472777
CCN2 in Skin FibrosisQ38979317
CCN2/decorin interactions: a novel approach to combating fibrosis?Q39755174
WISP1 overexpression promotes proliferation and migration of human vascular smooth muscle cells via AKT signaling pathway.Q40692253
The Effect of Pyrroloquinoline Quinone on the Expression of WISP1 in Traumatic Brain InjuryQ41532459
UVB and proinflammatory cytokines synergistically activate TNF-alpha production in keratinocytes through enhanced gene transcriptionQ41900868
Extracellular Matrix Reorganization During Wound Healing and Its Impact on Abnormal ScarringQ43179610
miR-92a regulates TGF-β1-induced WISP1 expression in pulmonary fibrosis.Q45956860
CCN4/WISP-1 positively regulates chondrogenesis by controlling TGF-β3 functionQ47135194
Identification of a myofibroblast-specific expression signature in skin woundsQ47967362
Inflammatory microenvironment and tumor necrosis factor alpha as modulators of periostin and CCN2 expression in human non-healing skin wounds and dermal fibroblasts.Q52958417
P4510describes a project that usesImageJQ1659584
P921main subjectwound healingQ1509074
Cellular communication network factor 4Q21992573
P304page(s)533-546
P577publication date2018-01-09
P1433published inMatrix BiologyQ6787851
P1476titleCCN4/WISP1 controls cutaneous wound healing by modulating proliferation, migration and ECM expression in dermal fibroblasts via α5β1 and TNFα.
P478volume68-69

Reverse relations

cites work (P2860)
Q95831588Activin-mediated alterations of the fibroblast transcriptome and matrisome control the biomechanical properties of skin wounds
Q89078553CD44-dependent inflammation, fibrogenesis, and collagenolysis regulates extracellular matrix remodeling and tensile strength during cutaneous wound healing
Q89701833Carbon nanotubes promote cell migration in hydrogels
Q90031990Conjunction junction, what's the function? CCN proteins as targets in fibrosis and cancers
Q93186092Fibro-Adipogenic Progenitors Cross-Talk in Skeletal Muscle: The Social Network
Q58700915The role of CCN4/WISP-1 in the cancerous phenotype
Q102388692Wisp1 is a circulating factor that stimulates proliferation of adult mouse and human beta cells

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