| P50 | author | Charmaine J Simeonovic | Q87718572 |
| | Christopher R Parish | Q87718574 |
| | Barbara Ludwig | Q98957860 |
| P2093 | author name string | Stefan R Bornstein | |
| | Alberto Pugliese | |
| | Debra J Brown | |
| | Thomas W H Kay | |
| | Helen E Thomas | |
| | Thomas Loudovaris | |
| | Craig Freeman | |
| | Lora M Starrs | |
| | Sarah K Popp | |
| | Andrew F Ziolkowski | |
| | J Dennis Wilson | |
| | Fui Jiun Choong | |
| P2860 | cites work | Mammalian heparanase: gene cloning, expression and function in tumor progression and metastasis | Q22010222 |
| | The Juvenile Diabetes Research Foundation Network for Pancreatic Organ Donors with Diabetes (nPOD) Program: goals, operational model and emerging findings | Q27009048 |
| | The streetlight effect in type 1 diabetes | Q27023064 |
| | Pancreatic biopsy as a procedure for detecting in situ autoimmune phenomena in type 1 diabetes: close correlation between serological markers and histological evidence of cellular autoimmunity | Q73932422 |
| | Identification of sulfated oligosaccharide-based inhibitors of tumor growth and metastasis using novel in vitro assays for angiogenesis and heparanase activity | Q78029718 |
| | Increased neutrophil elastase and proteinase 3 and augmented NETosis are closely associated with β-cell autoimmunity in patients with type 1 diabetes | Q87504016 |
| | Important role of heparan sulfate in postnatal islet growth and insulin secretion | Q46066878 |
| | Novel heparan sulfate structures revealed by monoclonal antibodies | Q46391304 |
| | Free radical generation during chemical depolymerization of heparin. | Q46648645 |
| | Effects of heparan sulfate proteoglycan syndecan-4 on the insulin secretory response in a mouse pancreatic β-cell line, MIN6. | Q47637882 |
| | Autoreactive T cells in type 1 diabetes | Q48004838 |
| | Detection of enterovirus in the islet cells of patients with type 1 diabetes: what do we learn from immunohistochemistry? Reply to Hansson SF, Korsgren S, Pontén F et al [letter]. | Q51852586 |
| | Upregulated Expression of Heparanase in the Vitreous of Patients With Proliferative Diabetic Retinopathy Originates From Activated Endothelial Cells and Leukocytes. | Q53223978 |
| | Islet heparan sulfate but not heparan sulfate proteoglycan core protein is lost during islet isolation and undergoes recovery post-islet transplantation. | Q53457111 |
| | The diagnosis of insulitis in human type 1 diabetes. | Q55057348 |
| | Pancreatic biopsy by minimal tail resection in live adult patients at the onset of type 1 diabetes: experiences from the DiViD study | Q57449051 |
| | Heparanase Is Essential for the Development of Acute Experimental Glomerulonephritis | Q57789449 |
| | Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stress | Q61512382 |
| | Biosynthesis of heparin. II. Formation of sulfamino groups | Q68515786 |
| | Islet loss and alpha cell expansion in type 1 diabetes induced by multiple low-dose streptozotocin administration in mice | Q73631463 |
| | Identification and purification of functional human beta-cells by a new specific zinc-fluorescent probe | Q73644478 |
| | Insulitis in human type 1 diabetes: a comparison between patients and animal models | Q27023712 |
| | Cloning of mammalian heparanase, an important enzyme in tumor invasion and metastasis | Q28138868 |
| | Functions of cell surface heparan sulfate proteoglycans | Q29618521 |
| | Hyaluronan and hyaluronan-binding proteins accumulate in both human type 1 diabetic islets and lymphoid tissues and associate with inflammatory cells in insulitis. | Q33959711 |
| | Heparanase: a key enzyme involved in cell invasion | Q34183747 |
| | Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients. | Q34244112 |
| | Recent lessons learned from prevention and recent-onset type 1 diabetes immunotherapy trials | Q34318993 |
| | Blood and islet phenotypes indicate immunological heterogeneity in type 1 diabetes | Q34393377 |
| | The peri-islet basement membrane, a barrier to infiltrating leukocytes in type 1 diabetes in mouse and human. | Q34471628 |
| | Heparanase powers a chronic inflammatory circuit that promotes colitis-associated tumorigenesis in mice | Q34876266 |
| | Analysis of islet inflammation in human type 1 diabetes. | Q34917032 |
| | Immune intervention for type 1 diabetes, 2013-2014 | Q35098402 |
| | Insulitis in human type 1 diabetes: The quest for an elusive lesion | Q35159105 |
| | Current concepts on the pathogenesis of type 1 diabetes--considerations for attempts to prevent and reverse the disease | Q35630698 |
| | Heparan sulfate and heparanase play key roles in mouse β cell survival and autoimmune diabetes | Q35640553 |
| | The role of heparan sulphate in inflammation | Q36569379 |
| | Insulitis and β-Cell Mass in the Natural History of Type 1 Diabetes. | Q36608775 |
| | Effect of the purinergic inhibitor oxidized ATP in a model of islet allograft rejection | Q36796093 |
| | Molecular composition of the peri-islet basement membrane in NOD mice: a barrier against destructive insulitis | Q36837298 |
| | Reduction of circulating neutrophils precedes and accompanies type 1 diabetes | Q36867514 |
| | Current advances and travails in islet transplantation | Q37360411 |
| | Heparanase and autoimmune diabetes. | Q37413886 |
| | Immunopathology of the human pancreas in type-I diabetes | Q37737985 |
| | State of the art of clinical islet transplantation and novel protocols of immunosuppression | Q37914760 |
| | Through the fog: recent clinical trials to preserve β-cell function in type 1 diabetes | Q38012381 |
| | Anti-cytokine therapies in T1D: Concepts and strategies | Q38091182 |
| | Islet inflammation in human type 1 diabetes mellitus | Q38287783 |
| | Short heparin sequences spaced by glycol-split uronate residues are antagonists of fibroblast growth factor 2 and angiogenesis inhibitors | Q38363705 |
| | Distinct patterns of heparan sulphate in pancreatic islets suggest novel roles in paracrine islet regulation | Q38956297 |
| | Role of heparanase-driven inflammatory cascade in pathogenesis of diabetic nephropathy | Q39162263 |
| | Involvement of heparan sulfate 3-O-sulfotransferase isoform-1 in the insulin secretion pathway | Q39295925 |
| | Heparanase is essential for the development of diabetic nephropathy in mice. | Q39782778 |
| | The Role of Heparanase in the Pathogenesis of Acute Pancreatitis: A Potential Therapeutic Target | Q42004230 |
| | Function of Isolated Pancreatic Islets From Patients at Onset of Type 1 Diabetes: Insulin Secretion Can Be Restored After Some Days in a Nondiabetogenic Environment In Vitro: Results From the DiViD Study | Q42166138 |
| | Infection of human islets of Langerhans with two strains of Coxsackie B virus serotype 1: assessment of virus replication, degree of cell death and induction of genes involved in the innate immunity pathway | Q42254652 |
| | Hydroxyl radicals depolymerize glomerular heparan sulfate in vitro and in experimental nephrotic syndrome | Q42547119 |
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | type-1 diabetes | Q124407 |
| P304 | page(s) | e0191360 | |
| P577 | publication date | 2018-02-07 | |
| P1433 | published in | PLOS One | Q564954 |
| P1476 | title | Loss of intra-islet heparan sulfate is a highly sensitive marker of type 1 diabetes progression in humans | |
| P478 | volume | 13 | |