Metabolic activation of chemical carcinogens by hepatic preparations from streptozotocin-treated rats

scientific article published in February 1989

Metabolic activation of chemical carcinogens by hepatic preparations from streptozotocin-treated rats is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/BF00505186
P698PubMed publication ID2524416

P2093author name stringP R Flatt
C Ioannides
S L Bass
J Trinick
A D Ayrton
P2860cites workSpecies differences in activating and inactivating enzymes related to the control of mutagenic metabolitesQ34178444
Liver microsomal cytochrome P-450 and related monooxygenase activities in genetically hyperglycemic (ob/ob and db/db) and lean streptozotocin-treated miceQ38356877
Effect of experimental diabetes on drug metabolism in the ratQ39159161
The cytochromes P-448--a unique family of enzymes involved in chemical toxicity and carcinogenesisQ39683773
Altered Activity of Hepatic Mixed-Function Monooxygenase Enzymes in Streptozotocin-induced Diabetic RatsQ39867850
Mechanism of induction of hepatic microsomal drug metabolizing enzymes by a series of barbituratesQ40348454
Metabolism of benzo(a)pyrene and benzo (a)pyrene derivatives to mutagenic products by highly purified hepatic microsomal enzymesQ42063715
Streptozotocin-induced diabetes modulates the metabolic activation of chemical carcinogensQ42204490
Revised methods for the Salmonella mutagenicity testQ50211560
Potentiation of the hepatotoxicity of N-nitrosodimethylamine by fasting, diabetes, acetone, and isopropanol.Q51642633
Cytochrome P-448 and the activation of toxic chemicals and carcinogens.Q53554767
Alterations of microsomal monooxygenase system and carcinogen metabolism by streptozotocin-induced diabetes in ratsQ53562824
The use of nicotinamide to modify the toxicity of streptozotocin diabetes without loss of antitumor activity.Q53709539
UPD-glucuronosyltransferase, epoxide hydrolase and gultathione S-transferaseQ57747366
Effect of streptozotocin on the glutathione S-transferases of mouse liver cytosolQ67278819
Mechanism of induction of cytochrome P-450ac (P-450j) in chemically induced and spontaneously diabetic ratsQ68138698
Decrease in the levels of a constitutive cytochrome P-450 (RLM5) in hepatic microsomes of diabetic ratsQ68942046
Metabolism of nitrosamines by purified rabbit liver cytochrome P-450 isozymesQ70058038
Cholesterol 7 alpha-hydroxylase of rat liver: an insulin sensitive enzymeQ70400946
Purification, characterization and regulation of five rat hepatic microsomal cytochrome P-450 isozymesQ70584258
Determination of glucose by an automatic analyserQ70606258
Glutathione S-transferase activities in rat liver: effect of some factors influencing the metabolism of xenobioticsQ71222925
Purification and characterization of liver microsomal cytochromes p-450: electrophoretic, spectral, catalytic, and immunochemical properties and inducibility of eight isozymes isolated from rats treated with phenobarbital or beta-naphthoflavoneQ71468820
Drug metabolism in a reconstituted system by diabetes-dependent hepatic cytochrome P-450Q71621887
Comparative effects of diabetogenic agents on hepatic drug metabolismQ72529896
THE METABOLISM OF DRUGS BY LIVER MICROSOMES FROM ALLOXAN-DIABETIC RATS: LONG TERM DIABETESQ76665355
P433issue2
P304page(s)135-139
P577publication date1989-02-01
P1433published inDiabetologiaQ5270140
P1476titleMetabolic activation of chemical carcinogens by hepatic preparations from streptozotocin-treated rats
P478volume32

Reverse relations

cites work (P2860)
Q41867914Induction of cytochrome P450III and P450IV family proteins in streptozotocin-induced diabetes
Q72559961The impact of type I diabetes on rat liver gamma-glutamyltranspeptidase

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