Intestinal epithelial cells with impaired autophagy lose their adhesive capacity in the presence of TNF-α.

scientific article published on 31 March 2012

Intestinal epithelial cells with impaired autophagy lose their adhesive capacity in the presence of TNF-α. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S10620-012-2133-4
P698PubMed publication ID22466076

P2093author name stringMasaya Saito
Osamu Yokosuka
Toru Sato
Makoto Arai
Keiko Saito
Koutaro Yokote
Sayuri Sazuka
Tatsuro Katsuno
Tomoo Nakagawa
Yoshiko Noguchi
P2860cites workInfliximab, azathioprine, or combination therapy for Crohn's diseaseQ56988763
Autophagy in the intestinal epithelium reduces endotoxin-induced inflammatory responses by inhibiting NF-κB activationQ63609779
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Loss of autophagy in the central nervous system causes neurodegeneration in miceQ28131804
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Regulation mechanisms and signaling pathways of autophagyQ29547416
NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentationQ29615617
Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entryQ29615618
Autophagy and metabolismQ29615974
3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytesQ29617843
Conserved role for autophagy in Rho1-mediated cortical remodeling and blood cell recruitmentQ30495074
TNF-alpha induces actin cytoskeleton reorganization in glomerular epithelial cells involving tyrosine phosphorylation of paxillin and focal adhesion kinaseQ30739769
Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variantQ33375721
The function of tumour necrosis factor and receptors in models of multi-organ inflammation, rheumatoid arthritis, multiple sclerosis and inflammatory bowel diseaseQ33782327
Adhesion complexes implicated in intestinal epithelial cell-matrix interactionsQ34071952
Tumor necrosis factor signaling.Q34185821
Regulation of proliferation, survival and apoptosis by members of the TNF superfamilyQ34269354
Small molecules enhance autophagy and reduce toxicity in Huntington's disease models.Q34626231
The activation dependent adhesion of macrophages to laminin involves cytoskeletal anchoring and phosphorylation of the alpha 6 beta 1 integrinQ36223077
Novel roles for alpha3beta1 integrin as a regulator of cytoskeletal assembly and as a trans-dominant inhibitor of integrin receptor function in mouse keratinocytesQ36290617
New links to the pathogenesis of Crohn disease provided by genome-wide association scansQ36984901
Autophagy as an important process in gut homeostasis and Crohn's disease pathogenesisQ37083978
Cytokine-induced F-actin reorganization in endothelial cells involves RhoA activationQ37138792
The potential for disease modification in Crohn's diseaseQ37687865
TNFR1-induced activation of the classical NF-κB pathwayQ37828175
Integrin structure, activation, and interactionsQ37855345
Integrin alpha3beta1 directs the stabilization of a polarized lamellipodium in epithelial cells through activation of Rac1.Q40533058
Integrins: role in cell adhesion and communicationQ41307237
Both endocytic and endogenous protein degradation in fibroblasts is stimulated by serum/amino acid deprivation and inhibited by 3-methyladenineQ41710692
Rapid Induction and Isolation of Focal Adhesion ComplexesQ42483319
Human-Restricted Bacterial Pathogens Block Shedding of Epithelial Cells by Stimulating Integrin ActivationQ42919010
Mucosal healing and anti TNFs in IBD.Q43139094
Bacteria hijack integrin-linked kinase to stabilize focal adhesions and block cell detachment.Q45986472
Autophagy controls Salmonella infection in response to damage to the Salmonella-containing vacuoleQ50083524
P433issue8
P921main subjectautophagyQ288322
TNFQ18032037
P304page(s)2022-2030
P577publication date2012-03-31
P1433published inDigestive Diseases and SciencesQ15716711
P1476titleIntestinal epithelial cells with impaired autophagy lose their adhesive capacity in the presence of TNF-α.
P478volume57

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cites work (P2860)
Q38099513Autophagy: a new target or an old strategy for the treatment of Crohn's disease?
Q38254327Biological pathways involved in the development of inflammatory bowel disease
Q92409140Crohn's Disease: Potential Drugs for Modulation of Autophagy
Q41969044Escherichia coli O157:H7 suppresses host autophagy and promotes epithelial adhesion via Tir-mediated and cAMP-independent activation of protein kinase A
Q37631619Inhibition of Autophagic Degradation Process Contributes to Claudin-2 Expression Increase and Epithelial Tight Junction Dysfunction in TNF-α Treated Cell Monolayers
Q37205898Intestinal epithelium and autophagy: partners in gut homeostasis
Q99578629Resveratrol alleviates intestinal mucosal barrier dysfunction in dextran sulfate sodium-induced colitis mice by enhancing autophagy
Q59799610The role of autophagy in colitis-associated colorectal cancer
Q36791743Three isoforms of the Atg16L1 protein contribute different autophagic properties

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