| scholarly article | Q13442814 |
| review article | Q7318358 |
| P2093 | author name string | Kassiotis G | |
| Kollias G | |||
| Kontoyiannis D | |||
| Douni E | |||
| P2860 | cites work | A new model for rheumatoid arthritis generated by engraftment of rheumatoid synovial tissue and normal human cartilage into SCID mice | Q71659765 |
| Thymic expression of the golli-myelin basic protein gene in the SJL/J mouse | Q71686658 | ||
| Induction of myelin basic protein-specific experimental autoimmune encephalomyelitis in C57BL/6 mice: mapping of T cell epitopes and T cell receptor V beta gene segment usage | Q71726948 | ||
| The type I interleukin-1 receptor acts in series with tumor necrosis factor (TNF) to induce arthritis in TNF-transgenic mice | Q71889641 | ||
| Control of established experimental allergic encephalomyelitis by inhibition of tumor necrosis factor (TNF) activity within the central nervous system using monoclonal antibodies and TNF receptor-immunoglobulin fusion proteins | Q72194401 | ||
| Modulation of the transcripts for tumor necrosis factor-alpha and its receptors in vivo | Q72285901 | ||
| Synergistic effect of interleukin-1 beta and tumor necrosis factor alpha on interleukin-8 gene expression in synovial fibroblasts. Evidence that interleukin-8 is the major neutrophil-activating chemokine released in response to monokine activation | Q72547418 | ||
| Circulating levels of tumor necrosis factor soluble receptors in systemic lupus erythematosus are significantly higher than in other rheumatic diseases and correlate with disease activity | Q73076877 | ||
| IL-1 alpha and TNF-alpha are required for IL-12-induced development of Th1 cells producing high levels of IFN-gamma in BALB/c but not C57BL/6 mice | Q74195844 | ||
| A role for TNF-alpha and mucosal T helper-1 cytokines in the pathogenesis of Crohn's disease | Q74460284 | ||
| A p55 TNF receptor immunoadhesin prevents T cell-mediated intestinal injury by inhibiting matrix metalloproteinase production | Q74477309 | ||
| TNF accelerates the onset but does not alter the incidence and severity of myelin basic protein-induced experimental autoimmune encephalomyelitis | Q74636533 | ||
| A tumor necrosis factor-induced model of human primary demyelinating diseases develops in immunodeficient mice | Q74636581 | ||
| Different roles of tumour necrosis factor alpha and interleukin 1 in murine streptococcal cell wall arthritis | Q77403524 | ||
| Mucosal immunoregulation and inflammatory bowel disease: new insights from murine models of inflammation | Q77579661 | ||
| TNF-induced enterocyte apoptosis in mice is mediated by the TNF receptor 1 and does not require p53 | Q77646954 | ||
| Local expression of TNFalpha in neonatal NOD mice promotes diabetes by enhancing presentation of islet antigens | Q77658430 | ||
| Mice lacking mature T and B lymphocytes develop arthritic lesions after immunization with type II collagen | Q77899668 | ||
| Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis | Q24564656 | ||
| Human tumor necrosis factor receptor p75/80 (CD120b) gene structure and promoter characterization | Q28117974 | ||
| Effects of anti-CD4 antibody treatment on lymphocyte subsets and stimulated tumor necrosis factor alpha production: a study of 29 multiple sclerosis patients entered into a clinical trial of cM-T412 | Q28235443 | ||
| Challenging cytokine redundancy: inflammatory cell movement and clinical course of experimental autoimmune encephalomyelitis are normal in lymphotoxin-deficient, but not tumor necrosis factor-deficient, mice | Q28506176 | ||
| Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection | Q28509078 | ||
| Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes | Q28593744 | ||
| Decreased sensitivity to tumour-necrosis factor but normal T-cell development in TNF receptor-2-deficient mice | Q28593915 | ||
| Immune and inflammatory responses in TNF alpha-deficient mice: a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune re | Q28594116 | ||
| TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40 | Q28610812 | ||
| The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor | Q28610826 | ||
| Role of cytokines in rheumatoid arthritis | Q29620713 | ||
| Treatment of ulcerative colitis in the cottontop tamarin using antibody to tumour necrosis factor alpha | Q33618096 | ||
| Spontaneous inflammatory demyelinating disease in transgenic mice showing central nervous system-specific expression of tumor necrosis factor alpha | Q33771960 | ||
| Inhibition of Thl responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells | Q34299001 | ||
| Early mucosal changes in Crohn's disease | Q34376449 | ||
| The type 1 receptor (CD120a) is the high-affinity receptor for soluble tumor necrosis factor | Q35739690 | ||
| Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the central nervous system of transgenic mice: models for multiple sclerosis with primary oligodendrogliopathy. | Q35753349 | ||
| Resistance to cerebral malaria in tumor necrosis factor-alpha/beta-deficient mice is associated with a reduction of intercellular adhesion molecule-1 up-regulation and T helper type 1 response | Q35765275 | ||
| Regulatory roles of tumor necrosis factor-alpha and interleukin-1 beta in monocyte chemoattractant protein-1-mediated pulmonary granuloma formation in the rat. | Q35796240 | ||
| The pathophysiology of tumor necrosis factors | Q36135208 | ||
| Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts | Q36351406 | ||
| An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encephalomyelitis | Q36353675 | ||
| Tumor necrosis factor identified in multiple sclerosis brain | Q36356662 | ||
| Chronic tumor necrosis factor alters T cell responses by attenuating T cell receptor signaling | Q36377176 | ||
| Antiviral activity of tumor necrosis factor (TNF) is mediated via p55 and p75 TNF receptors | Q36380797 | ||
| Critical points of tumor necrosis factor action in central nervous system autoimmune inflammation defined by gene targeting | Q36380828 | ||
| Endogenous myelin basic protein inactivates the high avidity T cell repertoire | Q36401074 | ||
| A critical role of the p75 tumor necrosis factor receptor (p75TNF-R) in organ inflammation independent of TNF, lymphotoxin alpha, or the p55TNF-R. | Q36401608 | ||
| Inflammatory bowel disease (1) | Q37278321 | ||
| Shedding kinetics of soluble tumor necrosis factor (TNF) receptors after systemic TNF leaking during isolated limb perfusion. Relevance to the pathophysiology of septic shock. | Q37378024 | ||
| The two different receptors for tumor necrosis factor mediate distinct cellular responses | Q37609601 | ||
| High plasma level of soluble tumor necrosis factor receptor type II (sTNFRII) in asymptomatic HIV-1-infected patients | Q71542182 | ||
| Attenuation of collagen-induced arthritis in 55-kDa TNF receptor type 1 (TNFR1)-IgG1-treated and TNFR1-deficient mice | Q71555684 | ||
| Pattern of soluble TNF receptors I and II in sepsis | Q71585158 | ||
| Depressed Langerhans cell migration and reduced contact hypersensitivity response in mice lacking TNF receptor p75. | Q38502888 | ||
| Leukocyte-endothelial adhesion molecules | Q40392834 | ||
| Soluble receptors for tumour necrosis factor in clinical laboratory diagnosis. | Q40595922 | ||
| Double-blind, placebo-controlled multicenter trial using chimeric monoclonal anti-CD4 antibody, cM-T412, in rheumatoid arthritis patients receiving concomitant methotrexate | Q40678731 | ||
| HLA-D and IA antigens in rheumatoid arthritis and systemic lupus erythematosus | Q40682068 | ||
| Starving the synovium: angiogenesis and inflammation in rheumatoid arthritis | Q40848438 | ||
| Inhibition of Th1 polarization by soluble TNF receptor is dependent on antigen-presenting cell-derived IL-12. | Q40978670 | ||
| Tumor necrosis factors: developments during the last decade. | Q41020160 | ||
| Tumor necrosis factor alpha regulates proliferation in a mouse intestinal cell line | Q41119457 | ||
| Collagen-induced arthritis in CD4- or CD8-deficient mice: CD8+ T cells play a role in initiation and regulate recovery phase of collagen-induced arthritis | Q41195704 | ||
| Transgenic and knockout analyses of the role of TNF in immune regulation and disease pathogenesis. | Q41206974 | ||
| The potential biological and clinical significance of the soluble tumor necrosis factor receptors | Q41276467 | ||
| Induction of apoptosis in mature T cells by tumour necrosis factor | Q41293478 | ||
| Reciprocal IFN-gamma and TGF-beta responses regulate the occurrence of mucosal inflammation | Q41370537 | ||
| Transducing signals of life and death | Q41382894 | ||
| TNF receptors in the microvascular pathology of acute respiratory distress syndrome and cerebral malaria. | Q41453722 | ||
| Mononuclear cells from infants allergic to cow's milk secrete tumor necrosis factor alpha, altering intestinal function. | Q41462878 | ||
| Tumour necrosis factor and Crohn's disease | Q41491900 | ||
| Ligand passing: the 75-kDa tumor necrosis factor (TNF) receptor recruits TNF for signaling by the 55-kDa TNF receptor. | Q41528398 | ||
| Induction of apoptosis by the low-affinity NGF receptor | Q41541620 | ||
| The role of TNF alpha and related cytokines in the development and function of the autoreactive T-cell repertoire | Q41628498 | ||
| Synovial fibroblasts of patients with rheumatoid arthritis attach to and invade normal human cartilage when engrafted into SCID mice | Q41858761 | ||
| Tumor necrosis factor activates human endothelial cells through the p55 tumor necrosis factor receptor but the p75 receptor contributes to activation at low tumor necrosis factor concentration | Q42108713 | ||
| Differentiation of follicular dendritic cells and full antibody responses require tumor necrosis factor receptor-1 signaling | Q42573173 | ||
| Upregulation of NF-kappa B-dependent gene expression mediated by the p75 tumor necrosis factor receptor | Q42830189 | ||
| Immunoregulatory role of interleukin 10 in rheumatoid arthritis | Q42942352 | ||
| Association between Tumor Necrosis Factor-α and Disease Progression in Patients with Multiple Sclerosis | Q43876866 | ||
| T lymphocytes in collagen II-induced arthritis in mice. Characterization of arthritogenic collagen II-specific T-cell lines and clones | Q44700720 | ||
| Tumor necrosis factor receptors in patients with chronic hepatitis B virus infection | Q45786097 | ||
| Modulation of proinflammatory cytokine production in tumour necrosis factor-alpha (TNF-alpha)-transgenic mice by treatment with cells engineered to secrete IL-4, IL-10 or IL-13. | Q45885757 | ||
| Anti-T cell receptor antibody treatment of rats with established autologous collagen-induced arthritis: suppression of arthritis without reduction of anti-type II collagen autoantibody levels | Q46347384 | ||
| Control of IL-12 and IFN-gamma production in response to live or dead bacteria by TNF and other factors | Q47756992 | ||
| Differential tolerance is induced in T cells recognizing distinct epitopes of myelin basic protein | Q47992214 | ||
| Control of Leishmania major infection in mice lacking TNF receptors. | Q48032268 | ||
| Crucial role of tumor necrosis factor (TNF) receptor 2 and membrane-bound TNF in experimental cerebral malaria | Q48037129 | ||
| TANK, a co-inducer with TRAF2 of TNF- and CD 40L-mediated NF-kappaB activation | Q48064873 | ||
| Astrocyte-specific but not neuron-specific transmembrane TNF triggers inflammation and degeneration in the central nervous system of transgenic mice | Q48825088 | ||
| Increased MRI activity and immune activation in two multiple sclerosis patients treated with the monoclonal anti-tumor necrosis factor antibody cA2. | Q48851709 | ||
| Two tumour necrosis factor receptors: structure and function. | Q49167492 | ||
| A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group. | Q53964227 | ||
| Defective co-stimulation and impaired Th1 development in tumor necrosis factor/lymphotoxin-alpha double-deficient mice infected with Candida albicans. | Q54145900 | ||
| Apoptosis of CD8+ T cells is mediated by macrophages through interaction of HIV gp120 with chemokine receptor CXCR4. | Q55067967 | ||
| Tumour necrosis factor as immunomodulator and mediator of monocyte cytotoxicity induced by itself, γ-interferon and interleukin-1 | Q59066301 | ||
| In vivo evidence for a functional role of both tumor necrosis factor (TNF) receptors and transmembrane TNF in experimental hepatitis | Q59276547 | ||
| Predominant pathogenic role of tumor necrosis factor in experimental colitis in mice | Q59276550 | ||
| TNF inhibition and sepsis — sounding a cautionary note | Q59600999 | ||
| Self-association of the Death Domains of the p55 Tumor Necrosis Factor (TNF) Receptor and Fas/APO1 Prompts Signaling for TNF and Fas/APO1 Effects | Q59707705 | ||
| Increased levels of soluble tumor necrosis factor receptors in the sera and synovial fluid of patients with rheumatic diseases | Q61628153 | ||
| Impaired On/Off Regulation of TNF Biosynthesis in Mice Lacking TNF AU-Rich Elements | Q62819809 | ||
| Tumor necrosis factor receptor p55 mediates deletion of peripheral cytotoxic T lymphocytesin vivo | Q63968527 | ||
| Wasting, ischemia, and lymphoid abnormalities in mice expressing T cell-targeted human tumor necrosis factor transgenes. | Q64976931 | ||
| Therapy against murine collagen-induced arthritis with T cell receptor Vβ-specific antibodies | Q67905091 | ||
| Stimulation of human synovial fibroblast DNA synthesis by recombinant human cytokines | Q68100776 | ||
| Low levels of interleukin-4 and high levels of transforming growth factor beta in rheumatoid synovitis | Q68895206 | ||
| Production of cytotoxic factor for oligodendrocytes by stimulated astrocytes | Q70359960 | ||
| Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro | Q70392550 | ||
| Stimulation of human T-cell proliferation by specific activation of the 75-kDa tumor necrosis factor receptor | Q70504053 | ||
| Treatment of septic shock with the tumor necrosis factor receptor:Fc fusion protein. The Soluble TNF Receptor Sepsis Study Group | Q71094855 | ||
| Serum concentrations of inflammatory mediators related to organ failure in patients with acute pancreatitis | Q71147580 | ||
| A double-blind, placebo-controlled study of anti-CD5 immunoconjugate in patients with rheumatoid arthritis. The Xoma RA Investigator Group | Q71160298 | ||
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | rheumatoid arthritis | Q187255 |
| inflammatory bowel diseases | Q917447 | ||
| multiple sclerosis | Q8277 | ||
| TNF | Q18032037 | ||
| P304 | page(s) | I32-9 | |
| P577 | publication date | 1999-11-01 | |
| P1433 | published in | Annals of the Rheumatic Diseases | Q4767876 |
| P1476 | title | The function of tumour necrosis factor and receptors in models of multi-organ inflammation, rheumatoid arthritis, multiple sclerosis and inflammatory bowel disease | |
| P478 | volume | 58 Suppl 1 |
| Q55001725 | A New Venue of TNF Targeting. |
| Q28145391 | A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains |
| Q34283353 | A role for parathyroid hormone-related protein in the pathogenesis of inflammatory/autoimmune diseases |
| Q30385933 | Activation of TRAIL-DR5 pathway promotes sensorineural degeneration in the inner ear. |
| Q33309488 | An extensive phenotypic characterization of the hTNFalpha transgenic mice |
| Q49097159 | Antisense oligonucleotides against TNFR1 prevent toxicity of TNF/IFNγ treatment in mouse tumor models |
| Q36228672 | Autoimmune arthritis associated with mutated interleukin (IL)-6 receptor gp130 is driven by STAT3/IL-7-dependent homeostatic proliferation of CD4+ T cells |
| Q35838247 | BALB/c-Fcgr2bPdcd1 mouse expressing anti-urothelial antibody is a novel model of autoimmune cystitis |
| Q33552079 | Critical role for tumor necrosis factor alpha in controlling the number of lumenal pathogenic bacteria and immunopathology in infectious colitis |
| Q34395739 | Demyelinating and neurologic events reported in association with tumor necrosis factor alpha antagonism: by what mechanisms could tumor necrosis factor alpha antagonists improve rheumatoid arthritis but exacerbate multiple sclerosis? |
| Q36433143 | Depressive symptoms are associated with tumor necrosis factor alpha in systemic lupus erythematosus |
| Q40644687 | Development of a mouse-feline chimeric antibody against feline tumor necrosis factor-alpha |
| Q35044815 | Divergent mechanisms of action of the inflammatory cytokines interleukin 1-beta and tumour necrosis factor-alpha in mouse cremasteric venules |
| Q43110024 | Docosahexaenoic acid (DHA) and docosapentaenoic acid (DPAn-6) algal oils reduce inflammatory mediators in human peripheral mononuclear cells in vitro and paw edema in vivo |
| Q34357992 | Downregulation of the NHE3-binding PDZ-adaptor protein PDZK1 expression during cytokine-induced inflammation in interleukin-10-deficient mice |
| Q42861037 | Elevated red blood cell distribution width and inflammation in printing workers |
| Q44627994 | Evidence that elastase is the TNF-R75 shedding enzyme in resting human polymorphonuclear leukocytes |
| Q49442283 | Fecal Microbiota Transplantation, Commensal Escherichia coli and Lactobacillus johnsonii Strains Differentially Restore Intestinal and Systemic Adaptive Immune Cell Populations Following Broad-spectrum Antibiotic Treatment |
| Q36826576 | Female temperament, tumor development and life span: relation to glucocorticoid and tumor necrosis factor alpha levels in rats |
| Q36025268 | Fibrin(ogen) exacerbates inflammatory joint disease through a mechanism linked to the integrin alphaMbeta2 binding motif |
| Q45193683 | Galectin-3: A Positive Regulator of Leukocyte Recruitment in the Inflamed Microcirculation. |
| Q34079566 | Gene therapy of chronic inflammatory disease |
| Q39086040 | Generation, characterization and therapeutic potential of anti-feline TNF-alpha MAbs for feline infectious peritonitis |
| Q37951648 | Genetic and genomic predictors of anti-TNF response |
| Q42183307 | Glucocorticoid receptor dimerization induces MKP1 to protect against TNF-induced inflammation |
| Q77451287 | IL-1 genes in myasthenia gravis: IL-1A -889 polymorphism associated with sex and age of disease onset |
| Q36955331 | Identification of intra-group, inter-individual, and gene-specific variances in mRNA expression profiles in the rheumatoid arthritis synovial membrane. |
| Q37486715 | Immunogenetics of drug-induced skin blistering disorders. Part II: synthesis |
| Q32134489 | Inhibition of tumour necrosis factor-alpha (TNFalpha)-induced NF-kappaB p52 converts the metabolic effects of microglial-derived TNFalpha on mouse cerebellar neurones to neurotoxicity |
| Q50249242 | Intestinal epithelial cells with impaired autophagy lose their adhesive capacity in the presence of TNF-α. |
| Q41476422 | Killing of Staphylococcus aureus in murine macrophages by chloroquine used alone and in combination with ciprofloxacin or azithromycin |
| Q38998367 | Low level tumor necrosis factor-alpha protects cardiomyocytes against high level tumor necrosis factor-alpha: brief insight into a beneficial paradox. |
| Q36449536 | Matrix metalloproteinases as modulators of inflammation |
| Q33760914 | Maturation-dependent licensing of naive T cells for rapid TNF production |
| Q26781272 | Mechanisms of Kidney Injury in Lupus Nephritis - the Role of Anti-dsDNA Antibodies |
| Q38430919 | Meta-analysis of TNF-α promoter -308A/G polymorphism and SLE susceptibility in Asian populations |
| Q40575624 | Monocytic fasciitis: a newly recognized clinical feature of tumor necrosis factor receptor dysfunction |
| Q37760062 | Neurological adverse events associated with anti-tumor necrosis factor α treatment |
| Q39588803 | Osteocyte apoptosis is mechanically regulated and induces angiogenesis in vitro. |
| Q34674295 | Panax notoginseng Attenuates Bleomycin-Induced Pulmonary Fibrosis in Mice |
| Q35742366 | Post-transcriptional regulation of proinflammatory proteins. |
| Q34071243 | Post-transcriptional regulation of tumour necrosis factor alpha production |
| Q40847654 | Production of porcine TNFα by ADAM17-mediated cleavage negatively regulates porcine reproductive and respiratory syndrome virus infection |
| Q49132489 | Response of TNF-hyporesponsive SPRET/Ei mice in models of inflammatory disorders |
| Q34510873 | Rhesus macaque theta defensins suppress inflammatory cytokines and enhance survival in mouse models of bacteremic sepsis |
| Q77505446 | Severity of elastase-induced emphysema is decreased in tumor necrosis factor-alpha and interleukin-1beta receptor-deficient mice |
| Q21135491 | Shared molecular and functional frameworks among five complex human disorders: a comparative study on interactomes linked to susceptibility genes |
| Q38099248 | Side effects of TNF-α blockers in patients with psoriatic arthritis: evidences from literature studies |
| Q36155358 | Simian immunodeficiency virus-induced alterations in monocyte production of tumor necrosis factor alpha contribute to reduced immune activation in sooty mangabeys |
| Q36380447 | T0001, a variant of TNFR2-Fc fusion protein, exhibits improved Fc effector functions through increased binding to membrane-bound TNFα |
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| Q34542205 | TNF ligands and receptors--a matter of life and death |
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