VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds UBXN7

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-8956099)

VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds UBXN7 is …
instance of (P31):
biological processQ2996394

External links are
P2888exact matchhttps://identifiers.org/reactome:R-HSA-8956099
P3937Reactome IDR-HSA-8956099

P2860cites workThe structure and regulation of Cullin 2 based E3 ubiquitin ligases and their biological functionsQ26746044
UBXN7 docks on neddylated cullin complexes using its UIM motif and causes HIF1α accumulationQ34248457
Role of the NEDD8 modification of Cul2 in the sequential activation of ECV complexQ35249854
NEDD8 links cullin-RING ubiquitin ligase function to the p97 pathwayQ35947206
DCNL1 functions as a substrate sensor and activator of cullin 2-RING ligaseQ39196067
Mitochondrial MUL1 E3 ubiquitin ligase regulates Hypoxia Inducible Factor (HIF-1α) and metabolic reprogramming by modulating the UBXN7 cofactor proteinQ89475475
UBXN7 cofactor of CRL3KEAP1 and CRL2VHL ubiquitin ligase complexes mediates reciprocal regulation of NRF2 and HIF-1α proteinsQ112978064
P703found in taxonHomo sapiensQ15978631
P527has part(s)UBX domain protein 7Q21111016
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol]Q50269383
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5:UBXN7 [cytosol]Q50269388
MUL1 dimer [mitochondrial outer membrane]Q112974923
P361part ofNeddylationQ45317714