Pharmacodynamics, pharmacokinetics and safety of ticagrelor in Asian patients with stable coronary artery disease.

scientific article published on 17 June 2014

Pharmacodynamics, pharmacokinetics and safety of ticagrelor in Asian patients with stable coronary artery disease. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S12928-014-0277-1
P698PubMed publication ID24935072

P2093author name stringY Hiasa
R Teng
H Emanuelsson
P2860cites workMatching the evaluation of the clinical efficacy of clopidogrel to platelet function tests relevant to the biological properties of the drugQ28187017
Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevationQ28188284
Pharmacodynamics, pharmacokinetics, and safety of the oral reversible P2Y12 antagonist AZD6140 with aspirin in patients with atherosclerosis: a double-blind comparison to clopidogrel with aspirinQ28195019
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Safety, tolerability, pharmacokinetics and pharmacodynamics of high single-ascending doses of ticagrelor in healthy volunteersQ33163280
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Pharmacokinetics, pharmacodynamics, safety and tolerability of multiple ascending doses of ticagrelor in healthy volunteersQ34019342
Randomized double-blind assessment of the ONSET and OFFSET of the antiplatelet effects of ticagrelor versus clopidogrel in patients with stable coronary artery disease: the ONSET/OFFSET study.Q34020220
Absorption, distribution, metabolism, and excretion of ticagrelor in healthy subjectsQ34120974
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Evaluating the risk-benefit profile of the direct-acting P2Y(12) inhibitor ticagrelor in acute coronary syndromesQ37959155
Genetic polymorphisms and drug interactions leading to clopidogrel resistance: why the Asian population requires special attention.Q38056525
Pharmacokinetics and tolerability of single and multiple doses of ticagrelor in healthy Chinese subjects: an open-label, sequential, two-cohort, single-centre studyQ38479485
Pharmacokinetics, pharmacodynamics, tolerability and safety of single ascending doses of ticagrelor, a reversibly binding oral P2Y(12) receptor antagonist, in healthy subjectsQ43187673
Ticagrelor binds to human P2Y(12) independently from ADP but antagonizes ADP-induced receptor signaling and platelet aggregation.Q45954831
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Comparison of ticagrelor, the first reversible oral P2Y(12) receptor antagonist, with clopidogrel in patients with acute coronary syndromes: Rationale, design, and baseline characteristics of the PLATelet inhibition and patient Outcomes (PLATO) triaQ46068914
Clopidogrel resistance in Japanese patients scheduled for percutaneous coronary interventionQ46184554
In vitro evaluation of potential drug-drug interactions with ticagrelor: cytochrome P450 reaction phenotyping, inhibition, induction, and differential kineticsQ48302970
P433issue4
P921main subjectpharmacokineticsQ323936
pharmacodynamicsQ725307
P304page(s)324-333
P577publication date2014-06-17
P1433published inCardiovascular intervention and therapeuticsQ27724051
P1476titlePharmacodynamics, pharmacokinetics and safety of ticagrelor in Asian patients with stable coronary artery disease.
P478volume29

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cites work (P2860)
Q59799852Compared efficacy of clopidogrel and ticagrelor in treating acute coronary syndrome: a meta-analysis
Q49540317Evaluation of pharmacokinetic, pharmacodynamic, efficacy, and safety data of low-dose ticagrelor versus standard dose in East Asians: a systematic review
Q48348319Higher Risk of Bleeding in Asians Presenting With ST-Segment Elevation Myocardial Infarction: Analysis of the National Inpatient Sample Database.
Q37198888Low-dose ticagrelor yields an antiplatelet efficacy similar to that of standard-dose ticagrelor in healthy subjects: an open-label randomized controlled trial
Q42023858Pharmacodynamics, pharmacokinetics, and safety of ticagrelor in Chinese patients with stable coronary artery disease
Q42694846Pharmacokinetic Profiles of Ticagrelor Orodispersible Tablets in Healthy Western and Japanese Subjects
Q64079786Pharmacokinetic and Pharmacogenetic Factors Contributing to Platelet Function Recovery After Single Dose of Ticagrelor in Healthy Subjects
Q92717119Prediction of Ticagrelor and its Active Metabolite in Liver Cirrhosis Populations Using a Physiologically Based Pharmacokinetic Model Involving Pharmacodynamics
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Q27006031Ticagrelor: Pharmacokinetic, Pharmacodynamic and Pharmacogenetic Profile: An Update
Q38352069Ticagrelor: a review of its use in adults with acute coronary syndromes

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